James H. Hurley

Also affiliated with Goethe University Frankfurt, Neurosciences Institute, Research Network (United States), University of California, Berkeley

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 44 papers. Top paper: “ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer”.

ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer

The Journal of Cell Biology(2020)10.1083/jcb.201911047

N/A

0.692DataRank · unranked

100 citations

Adam L. Yokom, Chunxin Wang, Lindsey N. Young, Richard J. Youle, James H. Hurley +1 more

Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2315690121

N/A

0.655DataRank · unranked

78 citations

Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Kampmann, Ke Xu +2 more

Dynamics of upstream ESCRT organization at the HIV-1 budding site

Biophysical Journal(2023)10.1016/j.bpj.2023.05.020

N/A

0.396DataRank · unranked

13 citations

James H. Hurley, Gregory A. Voth, Arpa Hudait

Structural basis for growth factor and nutrient signal integration on the lysosomal membrane by mTORC1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.15.623810

N/A

0.208DataRank · unranked

3 citations

Alessandra Esposito, Gennaro Napolitano, Andrea Ballabio, James H. Hurley, Zhicheng Cui

Kinetic investigation reveals an HIV-1 Nef-dependent increase in AP-2 recruitment and productivity at endocytic sites

Molecular Biology of the Cell(2023)10.1091/mbc.e23-04-0126

N/A

0.195DataRank · unranked

2 citations

Anna Ye, Cyna Shirazinejad, James H. Hurley, David G. Drubin, Yuichiro Iwamoto

Crystallization of the Protein Kinase Cδ C1B Domain

Protein Kinase C Protocols10.1385/1-59259-397-6:299

N/A

0.165DataRank · unranked

2 citations

James H. Hurley, Gongyi Zhang

Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes

PLoS ONE(2021)10.1371/journal.pone.0250318

N/A

0.165DataRank · unranked

2 citations

Evan M. Green, Jörg Votteler, Dong Young Kim, Xuefeng Ren, Bei Yang +8 more

Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55

The FASEB Journal(2009)10.1096/fasebj.23.1_supplement.864.1

N/A

0.141DataRank · unranked

1 citations

Natalie Elia, Rodolfo Ghirlando, Jennifer Lippincott‐Schwartz, James H. Hurley, Hyung Ho Lee

Structural Basis for Membrane Recruitment of ATG16L1 by WIPI2 in Autophagy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.14.444175

N/A

0.104DataRank · unranked

1 citations

Chunmei Chang, C. Alexander Boecker, Thomas G. Flower, Cosmo Z. Buffalo, Xuefeng Ren +4 more

Structural mechanism for amino acid-dependent Rag GTPase switching by SLC38A9

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.28.225524

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0DataRank · unranked

0 citations

Rosalie Lawrence, James H. Hurley, Simon A. Fromm

Crystallographic molecular replacement using an in silico‐generated search model of SARS‐CoV‐2 ORF8

Protein Science(2021)10.1002/pro.4050

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0DataRank · unranked

55 citations

James H. Hurley, Thomas G. Flower

Structural basis for the ARF GAP activity and specificity of the C9orf72 complex

Nature Communications(2021)10.1038/s41467-021-24081-0

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0DataRank · unranked

31 citations

Simon A. Fromm, Jonathan Remis, Daniel B. Toso, James H. Hurley, Ming-Yuan Su

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.08.425958

N/A

0DataRank · unranked

6 citations

Xiaoshan Shi, Liv Jensen, Adam L. Yokom, Dorotea Fracchiolla, Sascha Martens +2 more

Crystallographic molecular replacement using an in silico -generated search model of SARS-CoV-2 ORF8

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.05.425441

N/A

0DataRank · unranked

2 citations

James H. Hurley, Thomas G. Flower

Clathrin-associated AP-1 controls termination of STING signalling

Nature(2022)10.1038/s41586-022-05354-0

N/A

0DataRank · unranked

153 citations

Pengbiao Xu, Sophie Rivara, Chong Liu, Jonathan Ricci, Xuefeng Ren +3 more

In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2205590119

N/A

0DataRank · unranked

60 citations

Kevin P. Larsen, Chenxi Ou, Kevin Rose, James H. Hurley, Sankalp Shukla

Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation

Science Advances(2022)10.1126/sciadv.add2926

N/A

0DataRank · unranked

41 citations

Roberta Peruzzo, Simon A. Fromm, Adam L. Yokom, Roberto Zoncu, James H. Hurley +1 more

Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204536119

N/A

0DataRank · unranked

38 citations

Mark Remec Pavlin, Juan P. Castillo, Alex Tong, Kevin P. Larsen, Xuefeng Ren +7 more

Longin domain GAP complexes in nutrient signalling, membrane traffic and neurodegeneration

FEBS Letters(2022)10.1002/1873-3468.14538

N/A

0DataRank · unranked

10 citations

James H. Hurley, Rachel M. Jansen

Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.03.490522

N/A

0DataRank · unranked

5 citations

Shanlin Rao, Martina Schuschnig, A. King Cada, Sascha Martens, Gerhard Hummer +2 more

In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.30.486420

N/A

0DataRank · unranked

1 citations

Kevin P. Larsen, Chenxi Ou, Kevin Rose, James H. Hurley, Sankalp Shukla

Structural basis for FLCN RagC GAP activation in TFEB substrate-selective mTORC1 regulation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.28.498039

N/A

0DataRank · unranked

0 citations

Roberta Peruzzo, Simon A. Fromm, Adam L. Yokom, Roberto Zoncu, James H. Hurley +1 more

Organization of Upstream ESCRT Machinery at the HIV-1 Budding Site

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.13.507863

N/A

0DataRank · unranked

0 citations

James H. Hurley, Gregory A. Voth, Arpa Hudait

Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor TFEB

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.12.507619

N/A

0DataRank · unranked

0 citations

Gennaro Napolitano, Mariana E. G. de Araújo, Alessandra Esposito, Jlenia Monfregola, Lukas A. Huber +3 more

Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

Nature(2023)10.1038/s41586-022-05652-7

N/A

0DataRank · unranked

191 citations

Gennaro Napolitano, Mariana E. G. de Araújo, Alessandra Esposito, Jlenia Monfregola, Lukas A. Huber +3 more

Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.28.555157

N/A

0DataRank · unranked

6 citations

Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Kampmann, Ke Xu +2 more

A Flat Protein Complex Shapes Rough ER Membrane Sheets

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.06.559866

N/A

0DataRank · unranked

2 citations

Liv Jensen, Janet B. Meehl, Kevin P. Larsen, Daniel A. Petito, James H. Hurley +2 more

Structural pathway for class III PI 3-kinase activation by the myristoylated GTP-binding pseudokinase VPS15

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.28.559894

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0DataRank · unranked

1 citations

Minghao Chen, Xuefeng Ren, Shanlin Rao, Samantha N. Garcia, Ainara Claveras Cabezudo +4 more

Kinetic investigation reveals an HIV-1 Nef-dependent increase in AP-2 recruitment and productivity at endocytic sites

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.18.537262

N/A

0DataRank · unranked

0 citations

Anna Ye, Cyna Shirazinejad, James H. Hurley, David G. Drubin, Yuichiro Iwamoto

Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca 2+ -sensor ALG-2

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.17.562764

N/A

0DataRank · unranked

0 citations

Wei Chen, Shanlin Rao, Serim Yang, Chenxi Ou, Kevin P. Larsen +4 more

Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca 2+ -sensor ALG-2

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2318046121

N/A

0DataRank · unranked

21 citations

W. Chen, Shanlin Rao, Serim Yang, Chenxi Ou, Kevin P. Larsen +4 more

Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2021785118

N/A

0DataRank · unranked

271 citations

Cosmo Z. Buffalo, Richard M. Hooy, Marc Allaire, Xuefeng Ren, James H. Hurley +1 more

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex

Nature Structural & Molecular Biology(2025)10.1038/s41594-025-01557-x

N/A

0DataRank · unranked

16 citations

Thanh Ngoc Nguyen, Xuefeng Ren, Grace Khuu, Annan SI Cook, Yuanchang Zhao +4 more

The human autophagy-initiating complexes ULK1C and PI3KC3-C1

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110391

N/A

0DataRank · unranked

12 citations

James H. Hurley, Minghao Chen

Structural basis for mTORC1 regulation by the CASTOR1-GATOR2 complex

Research Square(2025)10.21203/rs.3.rs-5073364/v1

N/A

0DataRank · unranked

1 citations

Clément Maghe, Karla Tapia, Selina Wu, Serim Yang, Xuefeng Ren +3 more

Structural pathway for PI3-kinase regulation by VPS15 in autophagy

Science(2025)10.1126/science.adl3787

N/A

0DataRank · unranked

29 citations

Minghao Chen, Thanh Ngoc Nguyen, Ainara Claveras Cabezudo, Grace Khuu, Shanlin Rao +8 more

A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy

The Journal of Cell Biology(2020)10.1083/jcb.201912098

N/A

0DataRank · unranked

116 citations

Chunmei Chang, James H. Hurley, Sascha Martens, Dorotea Fracchiolla

The ESCRTs – converging on mechanism

Journal of Cell Science(2020)10.1242/jcs.240333

N/A

0DataRank · unranked

88 citations

James H. Hurley, Mark Remec Pavlin

The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment

eLife(2020)10.7554/elife.59099

N/A

0DataRank · unranked

71 citations

Chunmei Chang, Adam L. Yokom, Liv Jensen, James H. Hurley, Xiaoshan Shi

A firehose for phospholipids

The Journal of Cell Biology(2020)10.1083/jcb.202003132

N/A

0DataRank · unranked

11 citations

James H. Hurley, William A. Prinz

Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.27.270637

N/A

0DataRank · unranked

47 citations

Cosmo Z. Buffalo, Richard M. Hooy, Marc Allaire, Xuefeng Ren, James H. Hurley +1 more

Structure of the lysosomal SCARF (L-SCARF) complex, an Arf GAP haploinsufficient in ALS and FTD

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.15.042515

N/A

0DataRank · unranked

4 citations

Roberto Zoncu, James H. Hurley, Ming-Yuan Su

A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.31.927327

N/A

0DataRank · unranked

3 citations

Yoshinori Takahashi, Arpa Hudait, Kevin Rose, Nicholas Tjahjono, Alexander J. Pak +7 more

The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.19.104315

N/A

0DataRank · unranked

2 citations

Chunmei Chang, Adam L. Yokom, James H. Hurley, Xiaoshan Shi