David E. Root

Biochemistry, Genetics and Molecular BiologyEngineering

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

9.7Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

Nature Neuroscience(2018)10.1038/s41593-018-0154-9

Top 4%

5.2DataRank

Top 4%584 citations

Chris Gaiteri, Sarah E. Sullivan, Charles C. White, Shinya Tasaki, Jishu Xu +17 more

Papers

Driven by 60 papers — median percentile 92. Top paper: “A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease”.

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

Nature Neuroscience(2018)10.1038/s41593-018-0154-9

Top 4%

5.2DataRank

Top 4%584 citations

Chris Gaiteri, Sarah E. Sullivan, Charles C. White, Shinya Tasaki, Jishu Xu +17 more

Noncanonical open reading frames encode functional proteins essential for cancer cell survival

Nature Biotechnology(2021)10.1038/s41587-020-00806-2

N/A

4.5DataRank · unranked

198 citations

Oana M. Enache, Victor Luria, Karsten Krug, Karl R. Clauser, Joshua M. Dempster +21 more

Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-3958

N/A

4.2DataRank · unranked

185 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +15 more

Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations

Nature Methods(2024)10.1038/s41592-024-02241-6

Top 8%

2.7DataRank

Top 8%124 citations

Beth A. Cimini, Amy Goodale, Lisa Miller, Maria Kost‐Alimova, Nasim Jamali +18 more

Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

Cell Metabolism(2020)10.1016/j.cmet.2020.10.018

N/A

2.7DataRank · unranked

81 citations

Kevin S. Kapner, Keisuke Yamamoto, Robert S. Banh, Jasper E. Neggers, Albert S.W. Sohn +7 more

Regulation of Cellular Heterogeneity and Rates of Symmetric and Asymmetric Divisions in Triple-Negative Breast Cancer

Cell Reports(2018)10.1016/j.celrep.2018.08.053

N/A

2.0DataRank · unranked

47 citations

Hadas Masury, Reba Condiotti, Yaakov Fixler, Yael Gabai, Tzofia Glikman +15 more

Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.05.475090

Top 12%

1.8DataRank

Top 12%51 citations

Beth A. Cimini, Amy Goodale, Lisa Miller, Maria Kost‐Alimova, Nasim Jamali +18 more

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1491

N/A

1.6DataRank · unranked

63 citations

Joana G. Marques, Tingjian Wang, Maria Trissal, Ilon Liu, Li Jiang +50 more

Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1213

N/A

1.5DataRank · unranked

42 citations

Neekesh V. Dharia, Guillaume Kugener, Alexandra B. Forman, Michael Rothberg, Mai Abdusamad +15 more

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

Molecular Cell(2024)10.1016/j.molcel.2023.12.003

N/A

1.5DataRank · unranked

69 citations

Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R. Clauser +19 more

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

Nature Communications(2022)10.1038/s41467-022-28198-8

N/A

1.3DataRank · unranked

58 citations

Zachary J. Reitman, Sophie D. Lu, Graham Buchan, Gabrielle Gionet, Frank Dubois +51 more

lincRNAs act in the circuitry controlling pluripotency and differentiation

Nature(2011)10.1038/nature10398

N/A

1.1DataRank · unranked

1897 citations

Julie Donaghey, Bryce W. Carey, Manuel Garber, Jennifer K. Grenier, Glen Munson +13 more

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

Cell(2009)10.1016/j.cell.2009.12.018

N/A

0.954DataRank · unranked

576 citations

Irit Gat-Viks, Bennett O.V. Shum, Amelie Dricot, Marciela M. de Grace, Liguo Wu +12 more

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

Cell(2011)10.1016/j.cell.2011.10.022

N/A

0.781DataRank · unranked

182 citations

Philipp Mertins, Maxim N. Artyomov, Alex K. Shalek, Matteo Iannacone, Mark F. Ciaccio +21 more

Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer

Cancer Research(2024)10.1158/0008-5472.can-24-0970

N/A

0.774DataRank · unranked

28 citations

Timothy D. Martin, Haley E. Manchester, Jenny Högström, Na Zhang, Emmalyn Lecky +14 more

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models

Journal of Clinical Investigation(2010)10.1172/jci44165

N/A

0.736DataRank · unranked

134 citations

Ron Chen, Leanne C. Sayles, Chenwei Lin, Randal G. Walker, Anna K. Gillespie +9 more

Non-canonical open reading frames encode functional proteins essential for cancer cell survival

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.10.981001

N/A

0.686DataRank · unranked

12 citations

Oana M. Enache, Victor Luria, Karsten Krug, Karl R. Clauser, Joshua M. Dempster +21 more

A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas

Cancer Discovery(2022)10.1158/2159-8290.cd-22-1230

N/A

0.665DataRank · unranked

83 citations

Tsukasa Shibue, Ashir A. Borah, Benjamin Gaeta, Linh He, Lisa Leung +18 more

Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state

Nature Communications(2022)10.1038/s41467-022-30463-9

N/A

0.550DataRank · unranked

38 citations

Murugappan Sathappa, Jamie A. Moroco, Wei Jiang, Yue Qian, Sumaiya Iqbal +22 more

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.04.539399

N/A

0.504DataRank · unranked

8 citations

Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R. Clauser +19 more

Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis

Cell Reports(2023)10.1016/j.celrep.2023.113355

N/A

0.497DataRank · unranked

12 citations

José A. Seoane, Kanako Yuki, Amanda T. Mah, Amber R. Smith, Kevin S. Kolahi +15 more

A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor

Nature Communications(2020)10.1038/s41467-020-16517-w

N/A

0.464DataRank · unranked

21 citations

Laura Heydmann, Che C. Colpitts, Houssein El Saghire, Federica Piccioni, Frank Jühling +18 more

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

UNC Libraries(2020)10.17615/ge7q-0q17

N/A

0.442DataRank · unranked

18 citations

Sean T. Bailey, David J. Kwiatkowski, Pasi A. Jänne, Jeffrey A. Engelman, Julián Carretero +35 more

EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes

Cancer Research(2023)10.1158/0008-5472.can-23-1475

N/A

0.434DataRank · unranked

17 citations

R. Taylor Durall, Nhi M. Luong, Hans J. Hertzler, Julianna Huang, Prafulla C. Gokhale +21 more

Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/605436

N/A

0.425DataRank · unranked

16 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +15 more

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.22.618529

N/A

0.391DataRank · unranked

9 citations

Julien Dilly, Shengwu Liu, Eejung Kim, Yuemin Bian, Srisathiyanarayanan Dharmaiah +24 more

Morphological map of under- and overexpression of genes in human cells

Nature Methods(2025)10.1038/s41592-025-02753-9

N/A

0.385DataRank · unranked

12 citations

Eric Alix, John Arévalo, Adriana Borowa, Patrick J. Byrne, William G Charles +51 more

Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-0998

N/A

0.385DataRank · unranked

12 citations

Jan Novotný, D. Gulhan, Isabella Klooster, Antuan V. Tran, Macy Kasbo +17 more

Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

Nature Communications(2024)10.1038/s41467-024-48957-z

N/A

0.385DataRank · unranked

12 citations

Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy +12 more

Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin

Communications Biology(2024)10.1038/s42003-024-06140-6

N/A

0.345DataRank · unranked

9 citations

Garrett W. Cooper, Benjamin P. Lee, Yongdong Su, Katie T. Skinner, Jenny Shim +33 more

Vps18 contributes to phagosome membrane integrity in Mycobacterium tuberculosis -infected macrophages

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.01.560397

N/A

0.269DataRank · unranked

5 citations

Amanda M. Marsh, Pooja Uchil, Neha Jain, Zach R. Baskir, Owen T. Glover +4 more

Targeting TRIP13 in Wilms Tumor with Nuclear Export Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.23.481521

N/A

0.269DataRank · unranked

5 citations

Benjamin P. Lee, Garrett W. Cooper, Jenny Shim, Hunter C. Jonus, Won Jun Kim +31 more

EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.15.553204

N/A

0.165DataRank · unranked

2 citations

R. Taylor Durall, Nhi M. Luong, Hans J. Hertzler, Julianna Huang, Prafulla C. Gokhale +21 more

Pan-cancer organoid validation of tumor outlier chromosomal amplification events

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.05.463147

N/A

0.104DataRank · unranked

1 citations

Kanako Yuki, José A. Seoane, Amanda T. Mah, Amber R. Smith, Kevin S. Kolahi +15 more

Supplemental Table 13 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476833.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 5 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476821.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion

Blood Advances(2022)10.1182/bloodadvances.2021006061

N/A

0DataRank · unranked

11 citations

Fabio Ticconi, Inge Snoeren, Ronghui Li, Hélène F.E. Gleitz, Glenn S. Cowley +20 more

Supplemental Table 5 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476821

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 10 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476842

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 6 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476818.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 12 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476836

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 11 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476839.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 11 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476839

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 7 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476815.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 7 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476815

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplementary Data from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476806

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 10 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476842.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 4 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476824

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 3 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476827.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 6 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476818

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 4 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476824.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 13 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476833

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplementary Data from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476806.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 2 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476830.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 8 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476812.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

Supplemental Table 12 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22476836.v1

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

UNC Libraries(2020)10.17615/hcw5-ff74

N/A

0DataRank · unranked

0 citations

Melissa Tai, Zaida G. Ramirez‐Ortiz, Nir Hacohen, Andrew D. Luster, Glenn S. Cowley +6 more

Supplemental Table 3 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476827

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

LKB1/ STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1353

N/A

0DataRank · unranked

46 citations

Praveen Suraneni, Hamza Celik, Andrew Volk, Qiang Wen, Te Ling +20 more

Supplemental Table 8 from Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

(2023)10.1158/1078-0432.22476812

N/A

0DataRank · unranked

0 citations

Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco +16 more

David E. Root

Indexed papers

Top data-sharing exemplar

Papers