Margaret A. Phillips

Also affiliated with Southwestern Medical Center, Southwestern Medical Center, The University of Texas Southwestern Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria”.

Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.001

N/A

0.425DataRank · unranked

16 citations

Suraksha Gahalawat, S. Ray, Nhi Ho, Yan Han, Kurt E. Ward +29 more

Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL)

ACS Infectious Diseases(2023)10.1021/acsinfecdis.2c00527

N/A

0.360DataRank · unranked

10 citations

Aloysus K. Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal +12 more

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00173

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0DataRank · unranked

47 citations

Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey I. Gerasyuto, Sreekanth Kokkonda +39 more

Discovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101219

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0DataRank · unranked

28 citations

Jue Liang, Colin Hanfrey, Margaret A. Phillips, Anthony J. Michael, Bin Li

Total synthesis of (+)-spiroindimicin A and congeners unveils their antiparasitic activity

Chemical Science(2021)10.1039/d1sc02838c

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0DataRank · unranked

26 citations

S. Ray, Leah S. Imlay, Lauren T. Callaghan, Hanspeter Niederstrasser, Prema L. Mallipeddi +5 more

Total Synthesis of (+)-Spiroindimicin A via Asymmetric Palladium-Catalyzed Spirocyclization

ChemRxiv(2021)10.26434/chemrxiv.14515014.v1

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0DataRank · unranked

1 citations

S. Ray, Leah S. Imlay, Lauren Callaghan, Hanspeter Niederstrasser, Prema L. Mallipeddi +5 more

Total Synthesis of (+)-Spiroindimicin A via Asymmetric Palladium-Catalyzed Spirocyclization

ChemRxiv(2021)10.26434/chemrxiv.14515014

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0DataRank · unranked

0 citations

S. Ray, Leah S. Imlay, Lauren Callaghan, Hanspeter Niederstrasser, Prema L. Mallipeddi +5 more

Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2213116119

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0DataRank · unranked

16 citations

Timothy C. Umland, Xiaoyi Deng, Farah El Mazouni, Sreekanth Kokkonda, Ruth Olson +11 more

Development of a biomarker to monitor target engagement after treatment with dihydroorotate dehydrogenase inhibitors

Biochemical Pharmacology(2022)10.1016/j.bcp.2022.115237

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0DataRank · unranked

2 citations

Christopher Leija, Zhiyu Zhao, Xiaoyu Wang, Jessica A. Kilgore, Belén Tornesi +4 more

A fast-killing tyrosine amide (( S )-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus ( Pf CARL)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.16.512381

N/A

0DataRank · unranked

0 citations

Aloysus K. Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal +12 more

Functional polyamine metabolic enzymes and pathways encoded by the virosphere

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2214165120

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0DataRank · unranked

18 citations

Jue Liang, Hamid Baniasadi, Margaret A. Phillips, Anthony J. Michael, Bin Li

Neofunctionalization of S-adenosylmethionine decarboxylase into pyruvoyl-dependent L-ornithine and L-arginine decarboxylases is widespread in bacteria and archaea

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105005

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0DataRank · unranked

1 citations

Jue Liang, Margaret A. Phillips, Anthony J. Michael, Bin Li

Modular Total Synthesis of the 5/5-Spirocyclic Spiroindimicins

ChemRxiv(2023)10.26434/chemrxiv-2023-zcrr5

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0DataRank · unranked

3 citations

Tiffany A. Brisco, S. Ray, Arani Datta, Xiaoyu Zhang, Zhen Zhang +8 more

WITHDRAWN: Knockout of HD domain 5’-nucleotidase in T. brucei triggers cell death linked to DNA damage and downregulation of glutamine uptake

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.19.545529

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0DataRank · unranked

0 citations

Michael A. Pontikos, Hamid Baniasadi, Noelle S. Williams, Margaret A. Phillips, Yue Wen Deng

Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02394

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0DataRank · unranked

11 citations

Roger V. Bonnert, Jet Tsien, Xiaoyi Deng, Chris Higgs, Farah El Mazouni +39 more

Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N1-aminopropylagmatine synthases

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107281

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0DataRank · unranked

11 citations

Jue Liang, Hamid Baniasadi, Shin Kurihara, Margaret A. Phillips, Anthony J. Michael +1 more

A hybrid biosynthetic-catabolic pathway for norspermidine production

Biochemical Journal(2024)10.1042/bcj20240411

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0DataRank · unranked

2 citations

Jue Liang, Margaret A. Phillips, Anthony J. Michael, Bin Li

Synthesis of the 5/5-spiroindimicin alkaloids: development of a general synthetic approach and biological investigations

Organic & Biomolecular Chemistry(2024)10.1039/d4ob01552e

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0DataRank · unranked

0 citations

Tiffany A. Brisco, S. Ray, Arani Datta, Xiaoyu Zhang, Zhen Zhang +8 more

New routes for spermine biosynthesis

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108390

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0DataRank · unranked

5 citations

Hamid Baniasadi, Jue Liang, Margaret A. Phillips, Anthony J. Michael, Bin Li

Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na + Pump ( Pf ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00436

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0DataRank · unranked

3 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na + pump ( Pf ATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.20.655166

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0DataRank · unranked

0 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Optimization of species-selective reversible proteasome inhibitors for the treatment of malaria

ChemRxiv(2025)10.26434/chemrxiv-2025-f64v2

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0DataRank · unranked

0 citations

S. Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Aloysus K. Lawong +21 more

The Pseudomonas aeruginosa Type VI secretion system toxin Tse8 evolved from a novel N-carbamoylputrescine amidohydrolase

Biochemical Journal(2025)10.1042/bcj20253210

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0DataRank · unranked

0 citations

Hamid Baniasadi, Margaret A. Phillips, Anthony J. Michael, Bin Li

Alternative pathways utilize or circumvent putrescine for biosynthesis of putrescine-containing rhizoferrin

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.016738

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0DataRank · unranked

14 citations

Xiaoyi Deng, Sok Ho Kim, Leann Buhrow, Diana R. Tomchick, Margaret A. Phillips +2 more

Optimization of species-selective reversible proteasome inhibitors for the treatment of malaria

ChemRxiv(2025)10.26434/chemrxiv-2025-f64v2-v2

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0DataRank · unranked

0 citations

S. Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Zhe Chen +22 more

Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00311

N/A

0DataRank · unranked

37 citations

Xiaoyi Deng, Karen L. White, Farah El Mazouni, John White, David M. Shackleford +24 more