Timothy S. McMillen

California Institute for Regenerative Medicine

Also affiliated with University of Washington, Maine Farmland Trust

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Enhancing fatty acid oxidation negatively regulates PPARs signaling in the heart”.

Enhancing fatty acid oxidation negatively regulates PPARs signaling in the heart

Journal of Molecular and Cellular Cardiology(2020)10.1016/j.yjmcc.2020.06.008

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20 citations

Jeffrey Ding, Timothy S. McMillen, Outi Villet, Rong Tian, Dan Shao +1 more

Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet

PLoS ONE(2020)10.1371/journal.pone.0242749

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24 citations

Marika Bogdani, Myrian Velasco, Timothy S. McMillen, Cecilia Ridaura, Lisa E. Kelly +6 more

Increasing fatty acid oxidation elicits a sex-dependent response in failing mouse hearts

Journal of Molecular and Cellular Cardiology(2021)10.1016/j.yjmcc.2021.05.004

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38 citations

Timothy S. McMillen, Outi Villet, Sara Young, Stephen C. Kolwicz, Taurence Senn +3 more

Upregulation of mitochondrial ATPase inhibitory factor 1 (ATPIF1) mediates increased glycolysis in mouse hearts

Journal of Clinical Investigation(2022)10.1172/jci155333

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53 citations

Arianne Caudal, Xiaoting Tang, Juan D. Chavez, Timothy S. McMillen, Andrew Keller +10 more

RETRACTED: dATP elevation induces myocardial metabolic remodeling to support improved cardiac function

Journal of Molecular and Cellular Cardiology(2022)10.1016/j.yjmcc.2022.11.010

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4 citations

Jason D. Murray, Galina Flint, Timothy S. McMillen, Gerhard Weber, Majid Shakeri +10 more

dATP Elevation Induces Myocardial Metabolic Remodeling to Support Improved Cardiac Function

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.07.515235

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1 citations

Jason D. Murray, Galina Flint, Timothy S. McMillen, Gerhard Weber, Majid Shakeri +10 more

Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2207615120

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60 citations

Timothy S. McMillen, Matthew C. Childers, Henry Gong, Michael Regnier, Thomas C. Irving +1 more

Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle

Circulation Research(2023)10.1161/circresaha.123.322629

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48 citations

Saffie Mohran, Kyrah L. Turner, Weikang Ma, Amy Martinson, Galina Flint +16 more

Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes

Cell Reports(2023)10.1016/j.celrep.2023.112641

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42 citations

Akira Yoshii, Lauren Abell, Bo Zhou, Ricardo F. Frausto, Julia Ritterhoff +6 more

Raising NAD + Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation

Circulation(2023)10.1161/circulationaha.123.066039

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39 citations

Hongye Chen, Aprajita S. Yadav, Julia Ritterhoff, Outi Villet, Timothy S. McMillen +7 more

Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.23.523684

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5 citations

Isabella M. Reichardt, Kristin A. Zabrecky, Alex J. Goldstein, Logan R.J. Bailey, Darrian Bugg +14 more

Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.526380

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5 citations

Saffie Mohran, Kyrah L. Turner, Weikang Ma, Galina Flint, Lin Qi +16 more

MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy

Journal of Molecular and Cellular Cardiology(2024)10.1016/j.yjmcc.2024.04.010

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14 citations

Saffie Mohran, Logan R.J. Bailey, Timothy S. McMillen, Kristina B. Kooiker, Neil B. Wood +8 more

Calcium has a direct effect on thick filament activation in porcine myocardium

The Journal of General Physiology(2024)10.1085/jgp.202413545

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9 citations

Timothy S. McMillen, Christian Mandrycky, An-Yue Tu, Kristina B. Kooiker, Wenjing Qian +7 more

13 C stable isotope tracing reveals distinct fatty acid oxidation pathways in proliferative versus oxidative cells

American Journal of Physiology-Cell Physiology(2024)10.1152/ajpcell.00611.2023

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5 citations

Timothy S. McMillen, Hanna Foundas, Roland Palkovacs, Gernot Poschet, Arianne Caudal +5 more

The structural and functional effects of myosin regulatory light chain phosphorylation are amplified by increases in sarcomere length and [Ca2+]

The Journal of Physiology(2024)10.1113/jp286802

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5 citations

Blake J. Vander Top, Kristina B. Kooiker, Saffie Mohran, Christian Mandrycky, Timothy S. McMillen +5 more

Mechanisms of a novel regulatory light chain–dependent cardiac myosin inhibitor

The Journal of General Physiology(2024)10.1085/jgp.202313503

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3 citations

Qing-Fen Gan, Ming Yu, Na Sa, Saffie Mohran, Yuanhua Cheng +11 more

MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient-induced stem cell-derived cardiomyocyte model of hypertrophic cardiomyopathy

Biophysical Journal(2024)10.1016/j.bpj.2023.11.1955

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0 citations

Saffie Mohran, Logan R.J. Bailey, Timothy S. McMillen, Kristina B. Kooiker, Neil B. Wood +8 more

Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy

Science(2025)10.1126/science.adv9157

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9 citations

Isabella M. Reichardt, Kristin A. Zabrecky, Abigail Nagle, Logan R.J. Bailey, Darrian Bugg +17 more

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

Journal of Molecular and Cellular Cardiology(2025)10.1016/j.yjmcc.2025.10.008

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2 citations

Saffie Mohran, Matthew C. Childers, Timothy S. McMillen, Ateeqa Naim, Matvey Pilagov +14 more

Myosin modulator Aficamten inhibits force in cardiac muscle by altering myosin’s biochemical activity without changing thick filament structure

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.14.654110

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3 citations

Kristina B. Kooiker, Ateeqa Naim, Matvey Pilagov, Anthony Asencio, Kyrah L. Turner +13 more

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.27.672708

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3 citations

Saffie Mohran, Matthew C. Childers, Timothy S. McMillen, Ateeqa Naim, Matvey Pilagov +14 more