James R. Heath

Also affiliated with Institute for Systems Biology, Parker Institute for Cancer Immunotherapy

EngineeringImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

8.7Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2.

Research Square(2020)10.21203/rs.3.rs-51964/v1

Top 5%

4.7DataRank

Top 5%166 citations

Marissa Vignali, Mark Klinger, Jennifer N. Dines, Ian M. Kaplan, Emily Svejnoha +22 more

Papers

Driven by 61 papers — median percentile 83. Top paper: “Single-cell analysis tools for drug discovery and development”.

Single-cell analysis tools for drug discovery and development

Nature Reviews Drug Discovery(2016)10.1038/nrd.2015.16

N/A

10.9DataRank · unranked

486 citations

Antoni Ribas, Paul S. Mischel, James R. Heath

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

Cell(2020)10.1016/j.cell.2020.10.037

N/A

9.7DataRank · unranked

643 citations

Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Chengzhen L. Dai +50 more

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2.

Research Square(2020)10.21203/rs.3.rs-51964/v1

Top 5%

4.7DataRank

Top 5%166 citations

Marissa Vignali, Mark Klinger, Jennifer N. Dines, Ian M. Kaplan, Emily Svejnoha +22 more

Non-viral precision T cell receptor replacement for personalized cell therapy

Nature(2022)10.1038/s41586-022-05531-1

N/A

4.1DataRank · unranked

281 citations

Kyle Jacoby, Daniela A. Bota, Theresa Hunter, Zheng Pan, Eric Stawiski +49 more

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Genome Medicine(2023)10.1186/s13073-023-01173-8

N/A

1.5DataRank · unranked

78 citations

Estelle Talouarn, Astrid Marchal, Peng Zhang, Jérémy Manry, Yoann Seeleuthner +95 more

Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design

PLoS ONE(2023)10.1371/journal.pone.0286297

Top 16%

1.3DataRank

Top 16%62 citations

Tanayott Thaweethai, Shari B. Brosnahan, Mine Cicek, Megan L. Fitzgerald, Jason D. Goldman +95 more

Characteristics and Factors Associated with COVID-19 Infection, Hospitalization, and Mortality Across Race and Ethnicity

medRxiv(2020)10.1101/2020.10.14.20212803

Top 17%

1.2DataRank

Top 17%15 citations

Sergey A. Kornilov, Ryan Roper, Hannah Cohen‐Cline, Kathleen Jade, Brett Smith +6 more

A large-scale database of T-cell receptor beta sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Frontiers in Immunology(2025)10.3389/fimmu.2025.1488851

Top 20%

1.0DataRank

Top 20%45 citations

Marissa Vignali, Mark Klinger, Jennifer N. Dines, Ian M. Kaplan, Emily Svejnoha +24 more

Future cancer research priorities in the USA: a Lancet Oncology Commission

The Lancet Oncology(2017)10.1016/s1470-2045(17)30698-8

N/A

0.801DataRank · unranked

208 citations

Chi Van Dang, David B. Agus, Brian M. Alexander, Kenneth C. Anderson, Alan Ashworth +64 more

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Nature(2023)10.1038/s41586-023-06717-x

N/A

0.704DataRank · unranked

108 citations

Audrey V. Parent, Xian Liu, Axel Cederholm, Adrian Gervais, Jérémie Rosain +95 more

Characteristics and Factors Associated With Coronavirus Disease 2019 Infection, Hospitalization, and Mortality Across Race and Ethnicity

Clinical Infectious Diseases(2021)10.1093/cid/ciab154

N/A

0.617DataRank · unranked

60 citations

Sergey A. Kornilov, Ryan Roper, Hannah Cohen‐Cline, Kathleen Jade, Brett Smith +6 more

Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

Nature Communications(2021)10.1038/s41467-021-24293-4

N/A

0.505DataRank · unranked

28 citations

Alphonsus H. C. Ng, Frances Chow, Richard G. Everson, Beth A. Helmink, Michael T. Tetzlaff +6 more

The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies

Research Square(2022)10.21203/rs.3.rs-1225906/v1

N/A

0.483DataRank · unranked

24 citations

Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot +95 more

Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort

Nature Communications(2025)10.1038/s41467-025-65239-4

Top 43%

0.436DataRank

Top 43%16 citations

Sarah E. Donohue, Jeffrey N. Martin, Mady Hornig, Jarrod Mosier, Daniel J. Shinnick +49 more

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

Human Genetics and Genomics Advances(2024)10.1016/j.xhgg.2024.100300

N/A

0.306DataRank · unranked

6 citations

Elizabeth T. Cirulli, Iva Neveux, Evangelos Bellos, Ryan S. Thwaites, Kelly M. Schiabor Barrett +79 more

Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content

Advanced Healthcare Materials(2024)10.1002/adhm.202400622

N/A

0.241DataRank · unranked

4 citations

Xilal Y. Rima, Luong T. H. Nguyen, Xinyu Wang, Kwang Joo Kwak, Min Jin Yoon +20 more

KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19

Science(2022)10.1126/science.abi9591

N/A

0DataRank · unranked

248 citations

Maxim Zaslavsky, Yapeng Su, Jing Guo, Michael J. Sikora, Vincent van Unen +31 more

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2200413119

N/A

0DataRank · unranked

196 citations

Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot +95 more

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

The Journal of Experimental Medicine(2022)10.1084/jem.20220514

N/A

0DataRank · unranked

130 citations

Andrés Pizzorno, Lisa Miorin, Paul Bastard, Adrian Gervais, Tom Le Voyer +95 more

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

The Journal of Experimental Medicine(2022)10.1084/jem.20220131

N/A

0DataRank · unranked

117 citations

Daniela Matuozzo, Jérémie Le Pen, Danyel Lee, Leen Moens, Takaki Asano +94 more

Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

The Journal of Experimental Medicine(2022)10.1084/jem.20220202

N/A

0DataRank · unranked

56 citations

Zhiyong Liu, Qian Zhang, Marcela Moncada‐Vélez, Laura Covill, Peng Zhang +94 more

Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression

The Journal of Experimental Medicine(2022)10.1084/jem.20220551

N/A

0DataRank · unranked

50 citations

Yapeng Su, Daniel R. Calabrese, Daniel Chen, Janice Arakawa‐Hoyt, Kole T. Roybal +4 more

Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer

Frontiers in Oncology(2022)10.3389/fonc.2022.914594

N/A

0DataRank · unranked

33 citations

J. Lee, Priyanka Baloni, Christian Diener, James R. Heath, Yapeng Su +1 more

Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2203410119

N/A

0DataRank · unranked

8 citations

Pavlo A. Nesterenko, Jami McLaughlin, Weixian Deng, Giselle Burton Sojo, Donghui Cheng +20 more

Disease diagnostics using machine learning of immune receptors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.26.489314

N/A

0DataRank · unranked

19 citations

Erin Craig, Jackson Michuda, Nidhi Sehgal, Nikhil Ram-Mohan, Ji-Yeun Lee +31 more

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

medRxiv(2022)10.1101/2022.10.22.22281221

N/A

0DataRank · unranked

10 citations

Estelle Talouarn, Astrid Marchal, Jérémy Manry, Yoann Seeleuthner, Yu Zhang +95 more

Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy

Nature(2023)10.1038/s41586-023-05787-1

N/A

0DataRank · unranked

203 citations

Barbara Sennino, Songming Peng, Clifford L. Wang, Zheng Pan, Benjamin Yuen +51 more

Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia

The Journal of Experimental Medicine(2023)10.1084/jem.20220170

N/A

0DataRank · unranked

56 citations

Rebeca Pérez de Diego, Carlos Flores, Darawan Rinchai, Jordi Solé‐Violán, Àngela Deyà‐Martínez +92 more

T cell receptor sequences are the dominant factor contributing to the phenotype of CD8+ T cells with specificities against immunogenic viral antigens

Cell Reports(2023)10.1016/j.celrep.2023.113279

N/A

0DataRank · unranked

28 citations

Jingyi Xie, Yapeng Su, James R. Heath, Daniel Chen

Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis

Communications Biology(2023)10.1038/s42003-023-04899-8

N/A

0DataRank · unranked

18 citations

Jongchan Choi, Jingyi Xie, Mary E. Chaffee, Thomas M. Schmitt, Kathryn A. K. Finton +20 more

Effects of HLA single chain trimer design on peptide presentation and stability

Frontiers in Immunology(2023)10.3389/fimmu.2023.1170462

N/A

0DataRank · unranked

18 citations

Peter B. Rupert, Della Friend, Ana Dinca, Erica S. Lovelace, Matthew Buerger +8 more

Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities

Cell Systems(2023)10.1016/j.cels.2023.03.001

N/A

0DataRank · unranked

7 citations

William Chour, Diana C. DeLucia, Yapeng Su, Ana Jimena Pavlovitch-Bedzyk, Raymond T. Ng +5 more

Non-mass spectrometric targeted single-cell metabolomics

TrAC Trends in Analytical Chemistry(2023)10.1016/j.trac.2023.117300

N/A

0DataRank · unranked

6 citations

Yin Tang, Zhonghan Li, Zhili Guo, James R. Heath, Min Xue +2 more

Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions

Communications Chemistry(2023)10.1038/s42004-023-00890-w

N/A

0DataRank · unranked

2 citations

Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez‐Villalonga, Soo-Kyung Kim +4 more

Integrated antigenic and nucleic acid detection in single virions and virion-infected host-derived extracellular vesicles

medRxiv(2023)10.1101/2023.08.31.23292825

N/A

0DataRank · unranked

1 citations

Xilal Y. Rima, Luong T. H. Nguyen, Xinyu Wang, Kwang Joo Kwak, Min Jin Yoon +20 more

An NKG2A biased immune response confers protection for infection, autoimmune disease, and cancer

Research Square(2023)10.21203/rs.3.rs-3413673/v1

N/A

0DataRank · unranked

0 citations

Daniel Chen, Jingyi Xie, Jongchan Choi, Raymond T. Ng, Rongyu Zhang +13 more

Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer

Cell Reports(2024)10.1016/j.celrep.2024.113872

N/A

0DataRank · unranked

12 citations

Jingyi Xie, Jongchan Choi, Raymond T. Ng, Rongyu Zhang, Sarah Li +13 more

Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.19.581004

N/A

0DataRank · unranked

6 citations

C. Liu, Hui‐Yu Chuang, Xiaoyang Ye, Hanjun Cheng, James R. Heath +3 more

CITE-seq analysis reveals human cytomegalovirus and diabetes-associated adaptive NK cell alterations in cardiovascular disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.581997

N/A

0DataRank · unranked

1 citations

Daniel Chen, Sunil Kumar, James R. Heath, Matthew J. Feinstein, John R. Greenland +5 more

Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition

Cell Systems(2025)10.1016/j.cels.2025.101239

N/A

0DataRank · unranked

4 citations

C. Liu, Hui‐Yu Chuang, Xiaoyang Ye, Hanjun Cheng, James R. Heath +3 more

Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2

Nature Communications(2025)10.1038/s41467-025-65308-8

N/A

0DataRank · unranked

3 citations

Renée M. van der Sluis, Kennith Brian Castelino, Bao‐cun Zhang, Andreas Ronit, Thomas Zillinger +95 more

APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence

Nature Communications(2025)10.1038/s41467-025-56659-3

N/A

0DataRank · unranked

7 citations

Daniel Chen, William Chour, Raymond T. Ng, Rongyu Zhang, Dan Yuan +26 more

High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19

JCI Insight(2025)10.1172/jci.insight.191314

N/A

0DataRank · unranked

1 citations

Tasha Tsao, Irene Lui, Shion A. Lim, Yapeng Su, Ernie Chen +51 more

Whole-Proteome Screening and Multi-Modal Profiling of Antigen-Specific CD4+ T Cells at Single-Cell Resolution

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.21.649828

N/A

0DataRank · unranked

0 citations

Qi Jin, Michaela McKasson, Jongchan Choi, Vanessa Gutiérrez, Conor Brennan +35 more

Hematopoietic Stem Cells Respond Heterogeneously to Inflammatory Signals in an Age-Dependent Manner

Blood(2016)10.1182/blood.v128.22.566.566

N/A

0DataRank · unranked

0 citations

Mati Mann, Monika Kowalczyk, Carl de Boer, Jun Wang, Prisca Liberali +4 more

Systems Immunology of Long Covid: Insights from the STOP-PASC Clinical Trial

medRxiv(2025)10.64898/2025.12.04.25341650

N/A

0DataRank · unranked

0 citations

Woo Joo Kwon, Hong Zheng, Tyler R. Prestwood, Haley Hedlin, Jane W. Liang +24 more

Contributors

Genomic and Personalized Medicine(2013)10.1016/b978-0-12-382227-7.00124-5

N/A

0DataRank · unranked

0 citations

Minhaz Uddin Ahmed, Sun Hee Ahn, R. Rand Allingham, Jude Alsarraj, Matthew L. Anderson +228 more

Contributors

Genomic and Personalized Medicine(2009)10.1016/b978-0-12-369420-1.00122-0

N/A

0DataRank · unranked

0 citations

Matthew L. Anderson, Felicita Andreotti, Brian H. Annex, Anthony Antonellis, Dmitri Artemov +272 more

Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

Nature Communications(2020)10.1038/s41467-020-18376-x

N/A

0DataRank · unranked

173 citations

Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee +7 more

Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line

Nature Communications(2020)10.1038/s41467-020-15956-9

N/A

0DataRank · unranked

105 citations

Melissa E. Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica K. Wang +18 more

Visualizing Subcellular Enrichment of Glycogen in Live Cancer Cells by Stimulated Raman Scattering

Analytical Chemistry(2020)10.1021/acs.analchem.0c02348

N/A

0DataRank · unranked

53 citations

Jiajun Du, Rona Yu, Yapeng Su, James R. Heath, Lu Wei +1 more

Antibody-recruiting protein-catalyzed capture agents to combat antibiotic-resistant bacteria

Chemical Science(2020)10.1039/c9sc04842a

N/A

0DataRank · unranked

18 citations

Ajay Suresh Akhade, Mario L. Arrieta‐Ortiz, Bert Lai, Vivek Srinivas, James P. Hopkins +5 more

Reinfection with SARS-CoV-2 and Failure of Humoral Immunity: a case report

medRxiv(2020)10.1101/2020.09.22.20192443

N/A

0DataRank · unranked

103 citations

Kai Wang, Katharina Röltgen, Sandra C. A. Nielsen, Jared C. Roach, Samia N. Naccache +25 more

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.27.224063

N/A

0DataRank · unranked

17 citations

Daniel Chen, Christopher Lausted, Dan Yuan, Jongchan Choi, Cheng Dai +44 more

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Science Immunology(2021)10.1126/sciimmunol.abl4340

N/A

0DataRank · unranked

634 citations

Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Jérémy Manry +95 more

Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19

Nature Biotechnology(2021)10.1038/s41587-021-01020-4

N/A

0DataRank · unranked

119 citations

Yapeng Su, Priyanka Baloni, Daniel Chen, Ana Jimena Pavlovitch-Bedzyk, Dan Yuan +19 more

Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity across viruses

Immunity(2021)10.1016/j.immuni.2021.03.002

N/A

0DataRank · unranked

76 citations

Aditya Rao, Denis Đermadi, Jiaying Toh, Lara Murphy Jones, Michele Donato +12 more

Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19

medRxiv(2021)10.1101/2021.03.19.21254004

N/A

0DataRank · unranked

3 citations

Dan Yuan, Daniel Chen, Kai Wang, Jongchan Choi, Chengzhen L. Dai +51 more

Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.23.473930

N/A

0DataRank · unranked

2 citations

Maxim Zaslavsky, Yapeng Su, Michael J. Sikora, Vincent van Unen, Asbjørn Christophersen +27 more

Stereochemical engineering of a peptide macrocycle allosteric inhibitor of phospho-Akt2 controls cell penetration by fine-tuning macrocycle-cell membrane interactions

ChemRxiv(2021)10.26434/chemrxiv-2021-kldh7

N/A

0DataRank · unranked

0 citations

Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez‐Villalonga, William A. Goddard +2 more

Multiple early factors anticipate post-acute COVID-19 sequelae

Cell(2022)10.1016/j.cell.2022.01.014

N/A

0DataRank · unranked

1206 citations

Dan Yuan, Daniel Chen, Raymond T. Ng, Kai Wang, Jongchan Choi +68 more

James R. Heath

Indexed papers

Top data-sharing exemplar

Papers