🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Jesse Alt

Johns Hopkins University

ORCID: 0000-0001-5440-7891

Also affiliated with Johns Hopkins Medicine

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 16 papers. Top paper: “Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers”.

Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers

Cancer Immunology Research(2024)10.1158/2326-6066.cir-23-1105
N/A
0.590DataRank · unranked
50 citations

Fan Shen, Alex J. Lee, Liang Zhao, Thomas R. Nirschl, Debebe Theodros +18 more

Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement

Current Drug Metabolism(2021)10.2174/1389200222666210831125041
N/A
0.312DataRank · unranked
7 citations

Sadakatali S. Gori, Kathryn M. Lemberg, Arindom Pal, Vijayabhaskar Veeravalli, Ying Wu +8 more

Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115674
N/A
0.208DataRank · unranked
3 citations

Ajit G. Thomas, Ondřej Štěpánek, Brennan A. Murphy, Niyada Hin, Jan Skácel +10 more

Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity

Translational Psychiatry(2021)10.1038/s41398-021-01547-9
N/A
0DataRank · unranked
5 citations

Aparna Shah, Jacqueline D. Keighron, Ta-Chung M. Mou, Bruce Ladenheim, Jesse Alt +9 more

Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata

PNAS Nexus(2022)10.1093/pnasnexus/pgac297
N/A
0DataRank · unranked
13 citations

Sadakatali S. Gori, Jesse Alt, Sandhya P. Tiwari, Jitesh Iyer, Rashmi Talwar +25 more

1119 Glutamine antagonist prodrug JHU083 reprograms immunosuppressive tumor-associated macrophages to drives tumor immunity in urologic cancers

Regular and Young Investigator Award Abstracts(2022)10.1136/jitc-2022-sitc2022.1119
N/A
0DataRank · unranked
1 citations

Fan Shen, Thomas R. Nirschl, Alex J. Lee, Xiaoxu Wang, Liang Zhao +15 more

Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

Nature Communications(2023)10.1038/s41467-023-43304-0
N/A
0DataRank · unranked
35 citations

Jessica Shen, Shichun Lun, Liang Zhao, Jesse Alt, Benjamin Koleske +7 more

A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis

Science Translational Medicine(2023)10.1126/scitranslmed.abn7491
N/A
0DataRank · unranked
17 citations

Lauren Norris, Lukáš Tenora, Ivan Šnajdr, András K. Ponti, Xiaolei Zhu +10 more

Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity and improves motor function in a rabbit model of cerebral palsy

Journal of Controlled Release(2023)10.1016/j.jconrel.2023.04.017
N/A
0DataRank · unranked
16 citations

Zhi Zhang, Jesse Alt, Siva P. Kambhampati, Anjali Sharma, Sarabdeep Singh +8 more

Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01681
N/A
0DataRank · unranked
10 citations

Lukáš Tenora, Eva Prchalová, James Paule, Jesse Alt, Vijay Veeravalli +10 more

Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0258
N/A
0DataRank · unranked
2 citations

Eunüs S. Ali, Marcela Krečmerová, Joanna Marie H. Aguilar, Jesse Alt, Diane E. Peters +11 more

Targeting NAAG metabolism restores cognition and synaptic integrity in EcoHIV-infected mice

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00782
N/A
0DataRank · unranked
2 citations

Meixiang Huang, R. Michael Maragakis, Peter Pietri, Yu Su, Jesse Alt +7 more

Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome

Theranostics(2020)10.7150/thno.41714
N/A
0DataRank · unranked
28 citations

Anjali Sharma, Rajasekhar R. Ramireddy, Ajit G. Thomas, Jesse Alt, Amanda Fowler +7 more

Mass spectrometry-guided discovery of novel GCPII inhibitor scaffolds

Frontiers in Pharmacology(2025)10.3389/fphar.2025.1646207
N/A
0DataRank · unranked
0 citations

Ajit G. Thomas, John Janiszewski, Nate Hoxie, Chae Bin Lee, Ying Wu +13 more

Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury

Biochemical Pharmacology(2021)10.1016/j.bcp.2021.114796
N/A
0DataRank · unranked
42 citations

Silvia Picciolini, Seung‐Wan Yoo, Ajit G. Thomas, Arindom Pal, Jesse Alt +7 more

Development of EQ-6, a Novel Analogue of Ethoxyquin to Prevent Chemotherapy-Induced Peripheral Neuropathy

Neurotherapeutics(2021)10.1007/s13311-021-01093-8
N/A
0DataRank · unranked
7 citations

Jing Zhu, Xinghua Luan, Jun-Soon Kim, Byoungchol Oh, Cory Brayton +5 more