Hanwen Wang

Also affiliated with Johns Hopkins Medicine, Shanghai Electric (China)

MedicineBiochemistry, Genetics and Molecular BiologyMathematics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer”.

Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2020-002100

N/A

1.4DataRank · unranked

57 citations

Huilin Ma, Richard J. Sové, Leisha A. Emens, Aleksander S. Popel, Hanwen Wang

Virtual clinical trials of anti-PD-1 and anti-CTLA-4 immunotherapy in advanced hepatocellular carcinoma using a quantitative systems pharmacology model

Journal for ImmunoTherapy of Cancer(2022)10.1136/jitc-2022-005414

N/A

1.2DataRank · unranked

49 citations

Babita K. Verma, Hanwen Wang, Won Jin Ho, Mark Yarchoan, Aleksander S. Popel +1 more

Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response

ImmunoInformatics(2021)10.1016/j.immuno.2021.100002

N/A

0.844DataRank · unranked

31 citations

Chang Gong, Álvaro Ruiz-Martínez, Hanwen Wang, Emily F. Davis-Marcisak, Atul Deshpande +3 more

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

PLoS Computational Biology(2022)10.1371/journal.pcbi.1010254

N/A

0.621DataRank · unranked

62 citations

Chang Gong, Hanwen Wang, Richard J. Sové, Haoyang Mi, Holly Kimko +2 more

QSP‐IO: A Quantitative Systems Pharmacology Toolbox for Mechanistic Multiscale Modeling for Immuno‐Oncology Applications

CPT Pharmacometrics & Systems Pharmacology(2020)10.1002/psp4.12546

N/A

0.614DataRank · unranked

59 citations

Mohammad Jafarnejad, Chen Zhao, Hanwen Wang, Huilin Ma, Aleksander S. Popel +1 more

Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of immunotherapy in triple-negative breast cancer

iScience(2022)10.1016/j.isci.2022.104702

N/A

0.553DataRank · unranked

39 citations

Chen Zhao, Cesar A. Santa‐Maria, Leisha A. Emens, Aleksander S. Popel, Hanwen Wang

Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery

Cancer Research(2024)10.1158/0008-5472.can-24-0943

N/A

0.546DataRank · unranked

37 citations

Atul Deshpande, Babita K. Verma, Hanwen Wang, Haoyang Mi, Long Yuan +9 more

Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition

npj Precision Oncology(2023)10.1038/s41698-023-00405-9

N/A

0.529DataRank · unranked

33 citations

Theinmozhi Arulraj, Holly Kimko, Aleksander S. Popel, Hanwen Wang

Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

Frontiers in Pharmacology(2023)10.3389/fphar.2023.1163432

N/A

0.529DataRank · unranked

33 citations

Hanwen Wang, Yu Zhang, Jun Wang, Minu Pilvankar, Masoud Nickaeen +3 more

Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2410911121

N/A

0.416DataRank · unranked

15 citations

Hanwen Wang, Atul Deshpande, Ravi Varadhan, Leisha A. Emens, Elizabeth M. Jaffee +4 more

Eliciting the antitumor immune response with a conditionally activated PD‐L1 targeting antibody analyzed with a quantitative systems pharmacology model

CPT Pharmacometrics & Systems Pharmacology(2023)10.1002/psp4.13060

N/A

0.373DataRank · unranked

11 citations

Hanwen Wang, Yu Zhang, Vahideh Vakil, Hojjat Bazzazi, Aleksander S. Popel +1 more

Virtual clinical trials via a QSP immuno-oncology model to simulate the response to a conditionally activated PD-L1 targeting antibody in NSCLC

Journal of Pharmacokinetics and Pharmacodynamics(2024)10.1007/s10928-024-09928-5

N/A

0.373DataRank · unranked

11 citations

Hanwen Wang, Yu Zhang, Vahideh Vakil, Aleksander S. Popel, Alberto Ippolito

Identifying biomarkers for treatment of uveal melanoma by T cell engager using a QSP model

npj Systems Biology and Applications(2024)10.1038/s41540-024-00434-5

N/A

0.360DataRank · unranked

10 citations

Hanwen Wang, Theinmozhi Arulraj, Masoud Nickaeen, Minu Pilvankar, Jun Wang +3 more

Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.25.538191

N/A

0DataRank · unranked

0 citations

Theinmozhi Arulraj, Holly Kimko, Aleksander S. Popel, Hanwen Wang

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling

npj Digital Medicine(2024)10.1038/s41746-024-01188-4

N/A

0DataRank · unranked

91 citations

Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel, Hanwen Wang

Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model

Journal for ImmunoTherapy of Cancer(2020)10.1136/jitc-2020-001141

N/A

0DataRank · unranked

51 citations

Hanwen Wang, Richard J. Sové, Jun Wang, Craig Giragossian, Aleksander S. Popel +1 more

Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors

Frontiers in Bioengineering and Biotechnology(2020)10.3389/fbioe.2020.00141

N/A

0DataRank · unranked

52 citations

Richard J. Sové, Mohammad Jafarnejad, Sondra Rahmeh, Elizabeth M. Jaffee, Vered Stearns +4 more

Quantitative Systems Pharmacology Modeling in Immuno-Oncology: Hypothesis Testing, Dose Optimization, and Efficacy Prediction

Handbook of experimental pharmacology(2024)10.1007/164_2024_735

N/A

0DataRank · unranked

5 citations

Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel, Hanwen Wang

Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology

Briefings in Bioinformatics(2024)10.1093/bib/bbae131

N/A

0DataRank · unranked

15 citations

Hanwen Wang, Alberto Ippolito, Shuming Zhang, Elana J. Fertig, Aleksander S. Popel +1 more

Quantitative systems pharmacology modeling of macrophage‐targeted therapy combined with PD‐L1 inhibition in advanced NSCLC

Clinical and Translational Science(2024)10.1111/cts.13811

N/A

0DataRank · unranked

13 citations

Theinmozhi Arulraj, Samira Anbari, Aleksander S. Popel, Hanwen Wang

Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.11.553000

N/A

0DataRank · unranked

6 citations

Atul Deshpande, Babita K. Verma, Hanwen Wang, Hao‐Yang Mi, Long Yuan +9 more

A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition

Science Advances(2023)10.1126/sciadv.adg0289

N/A

0DataRank · unranked

29 citations

Hanwen Wang, Leisha A. Emens, Cesar A. Santa‐Maria, Aleksander S. Popel, Theinmozhi Arulraj