Daniel G. Isom

Also affiliated with American Orchid Society, Computing Center, Sylvester Comprehensive Cancer Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 21 papers. Top paper: “Predictable cholesterol binding sites in GPCRs lack consensus motifs”.

Predictable cholesterol binding sites in GPCRs lack consensus motifs

Structure(2021)10.1016/j.str.2021.01.004

N/A

0.663DataRank · unranked

82 citations

Jacob B. Rowe, Nicholas J. Kapolka, Daniel G. Isom, Geoffrey J. Taghon

Proton-gated coincidence detection is a common feature of GPCR signaling

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.08.425945

N/A

0.104DataRank · unranked

1 citations

Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, Daniel G. Isom +1 more

One Year of SARS-CoV-2: How Much Has the Virus Changed?

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.16.423071

N/A

0DataRank · unranked

33 citations

Daniel G. Isom, Santiago Vilar

An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.19.049387

N/A

0DataRank · unranked

0 citations

Zachary Lesecq, Katharine A. White, An Hoang, David A. Scott, Olga Zagnitko +6 more

Protons as Second Messenger Regulators of G Protein Signaling

UNC Libraries(2020)10.17615/h4wd-7g75

N/A

0DataRank · unranked

0 citations

Daniel G. Isom, Sarah T. Clement, Rachael Baker, Henrik Dohlman, Vishwajith Sridharan +1 more

Amino acid metabolites that regulate G protein signaling during osmotic stress

UNC Libraries(2020)10.17615/b5xj-qj51

N/A

0DataRank · unranked

0 citations

Sharon L. Campbell, Henrik Dohlman, Elizabeth Morin‐Kensicki, Guowei Yin, James P. Shellhammer +3 more

Regulation of Ras Paralog Thermostability by Networks of Buried Ionizable Groups

Figshare(2020)10.17615/we7q-fb43

N/A

0DataRank · unranked

0 citations

Daniel G. Isom, Henrik Dohlman, Vishwajith Sridharan

Differences in the Regulation of K-Ras and H-Ras Isoforms by Monoubiquitination

UNC Libraries(2020)10.17615/vnfk-w552

N/A

0DataRank · unranked

0 citations

Henrik Dohlman, Sharon L. Campbell, Daniel G. Isom, Rachael Baker, Kazutaka Sumita +2 more

Proton‐gated coincidence detection is a common feature of GPCR signaling

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04123

N/A

0DataRank · unranked

0 citations

Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, Daniel G. Isom +1 more

The evolution and mechanism of GPCR proton sensing

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.016352

N/A

0DataRank · unranked

74 citations

Nicholas J. Kapolka, Geoffrey J. Taghon, William M. Morgan, Daniel G. Isom, Jacob B. Rowe

Location-biased activation of the proton-sensor GPR65 is uncoupled from receptor trafficking

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2302823120

N/A

0DataRank · unranked

17 citations

Stephanie E. Crilly, Jacob B. Rowe, Daniel G. Isom, Manojkumar A. Puthenveedu, Loyda M. Morales Rodríguez

Compartment-Specific Activation of the Proton-Sensor GPR65 is Uncoupled from Receptor Trafficking

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.18.533272

N/A

0DataRank · unranked

1 citations

Stephanie E. Crilly, Jacob B. Rowe, Daniel G. Isom, Manojkumar A. Puthenveedu, Loyda M. Morales Rodríguez

Designer Autocrine Signaling Networks for Discovering GPCR-modulating Nanobodies

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.260740

N/A

0DataRank · unranked

0 citations

Kyutae Lee, Sam Taylor, Daniel G. Isom, Jacob M. Rowe

Quantifying Acid Adaptivity of Normal and Cancer Cells Using a Next Generation Genetically Encoded pH Biosensor

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.283790

N/A

0DataRank · unranked

0 citations

Sam Taylor, Kyutae Lee, Jacob B. Rowe, Daniel G. Isom

GPR1 and CMKLR1 Control Lipid Metabolism to Support the Development of Clear Cell Renal Cell Carcinoma

Cancer Research(2024)10.1158/0008-5472.can-23-2926

N/A

0DataRank · unranked

27 citations

Iqbal Mahmud, Vijay S. Thakur, Sze Kiat Tan, Daniel G. Isom, David B. Lombard +7 more

Advances in yeast synthetic biology for human G protein–coupled receptor biology and pharmacology

Current Opinion in Biotechnology(2024)10.1016/j.copbio.2024.103176

N/A

0DataRank · unranked

5 citations

Geoffrey J. Taghon, Daniel G. Isom, Nicholas J. Kapolka

PIONEER: A periplasmic display platform for synthetic biology-based screening of genetically encoded protein regulators

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110967

N/A

0DataRank · unranked

2 citations

Kyutae Lee, Daniel G. Isom, Jacob B. Rowe

Non-redundant roles for paralogous proteins in the yeast glucose-sensing pathway

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.07.680982

N/A

0DataRank · unranked

1 citations

Kshitiz Adhikari, Laura E. Herring, Daniel G. Isom, Shuang Li, Scott P. Lyons +5 more

PIONEER: A Periplasmic Display Platform for Synthetic Biology-Based Screening of Genetically Encoded Protein Regulators

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.26.684622

N/A

0DataRank · unranked

0 citations

Kyutae Lee, Daniel G. Isom, Jacob B. Rowe

Cholesterol Binds G Protein‐coupled Receptors in Conserved Sites Without Recurring Motifs

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.03682

N/A

0DataRank · unranked

0 citations

Jacob B. Rowe, Nicholas J. Kapolka, Daniel G. Isom, Geoffrey J. Taghon

Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1

Frontiers in Cell and Developmental Biology(2020)10.3389/fcell.2020.603688

N/A

0DataRank · unranked

29 citations

Balaji T. Moorthy, Devang M. Patel, Akhilesh Kumar, William M. Morgan, Belkis Alfonso +7 more