Denis Fourches

University of North Carolina at Chapel Hill

Also affiliated with Duke University, Institut Supérieur d’Electronique et des Réseaux & Télécommunications

Computer ScienceMaterials ScienceBiochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

9.8Author DataRank

Indexed papers

7in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 7 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Nature Communications(2019)10.1038/s41467-019-09799-2

Top 4%

5.0DataRank

Top 4%368 citations

Dennis Wang, Mike J. Mason, Bence Szalai, Krishna C. Bulusu, Yuanfang Guan +426 more

Papers

Driven by 35 papers — median percentile 48. Top paper: “Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen”.

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Nature Communications(2019)10.1038/s41467-019-09799-2

Top 4%

5.0DataRank

Top 4%368 citations

Dennis Wang, Mike J. Mason, Bence Szalai, Krishna C. Bulusu, Yuanfang Guan +426 more

CATMoS: Collaborative Acute Toxicity Modeling Suite

Environmental Health Perspectives(2021)10.1289/ehp8495

Top 4%

4.9DataRank

Top 4%142 citations

Agnes L. Karmaus, Jeremy Fitzpatrick, Grace Patlewicz, Prachi Pradeep, Domenico Alberga +95 more

QSAR without borders

Chemical Society Reviews(2020)10.1039/d0cs00098a

N/A

1.0DataRank · unranked

870 citations

Jürgen Bajorath, Robert P. Sheridan, Igor V. Tetko, Dmitry Filimonov, Vladimir Poroikov +14 more

A critical overview of computational approaches employed for COVID-19 drug discovery

Chemical Society Reviews(2021)10.1039/d0cs01065k

N/A

0.804DataRank · unranked

212 citations

Rommie E. Amaro, Carolina Horta Andrade, Nathan Brown, Sean Ekins, Denis Fourches +14 more

Structure-based virtual screening of perfluoroalkyl and polyfluoroalkyl substances (PFASs) as endocrine disruptors of androgen receptor activity using molecular docking and machine learning

Environmental Research(2020)10.1016/j.envres.2020.109920

N/A

0.590DataRank · unranked

50 citations

Phum Tachachartvanich, Denis Fourches, Anatoly A. Soshilov, Ching‐Yi Hsieh, Michele A. La Merrill +3 more

Cheminformatics: At the Crossroad of Eras

Challenges and Advances in Computational Chemistry and Physics(2014)10.1007/978-94-017-9257-8_16

N/A

0.467DataRank · unranked

8 citations

Denis Fourches

Protein-adaptive differential scanning fluorimetry using conformationally responsive dyes

Nature Biotechnology(2024)10.1038/s41587-024-02158-7

N/A

0.464DataRank · unranked

21 citations

Joshua C. Yu, Arundhati Suresh, Zachary J. Gale-Day, Matthew G. Alteen, Amanda S. Woo +9 more

Exploring drug space with ChemMaps.com

Bioinformatics(2018)10.1093/bioinformatics/bty412

N/A

0.416DataRank · unranked

15 citations

Nicole C Kleinstreuer, Denis Fourches, Alexandre Borrel

Palbociclib and Ribociclib Analogs Targeting CDK4 and CDK6 for Breast Cancer Treatment: A Molecular Modeling Study

10.26434/chemrxiv.12902504.v1

N/A

0.210DataRank · unranked

2 citations

sravya Kuchibhotla, Denis Fourches, Dhoha TRIKI

Computer-Assisted Decision Support for Student Admissions Based on Their Predicted Academic Performance

UNC Libraries(2020)10.17615/ayad-5482

N/A

0DataRank · unranked

0 citations

Alexander Tropsha, Margaret Reed Lewis, Eugene Muratov, Denis Fourches, Wendy C. Cox

Alarms about structural alerts

UNC Libraries(2020)10.17615/nzc7-rz81

N/A

0DataRank · unranked

0 citations

Stephen J. Capuzzi, Eugene N. Muratov, Alexander Sedykh, Olena Mokshyna, Sherif S. Farag +9 more

Tuning hERG Out: Antitarget QSAR Models for Drug Development

UNC Libraries(2020)10.17615/nrt4-8r96

N/A

0DataRank · unranked

0 citations

Meryck Felipe Brito da Silva, Rodolpho C. Braga, Eugene Muratov, Carolina Horta Andrade, Denis Fourches +2 more

Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds

UNC Libraries(2020)10.17615/n9k1-1442

N/A

0DataRank · unranked

0 citations

Nicole Kleinstreuer, Alexander Tropsha, Vinícius M. Alves, Denis Fourches, Eugene Muratov +2 more

QSAR models of human data can enrich or replace LLNA testing for human skin sensitization

UNC Libraries(2020)10.17615/3vcx-6145

N/A

0DataRank · unranked

0 citations

Nicole Kleinstreuer, Eugene Muratov, Denis Fourches, Alexander Tropsha, Judy Strickland +5 more

Computer-aided design of carbon nanotubes with the desired bioactivity and safety profiles

UNC Libraries(2020)10.17615/3523-ga22

N/A

0DataRank · unranked

0 citations

Liwen Li, Qingxin Mu, Denis Fourches, Bing Yan, Dongqiuye Pu +3 more

Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions

UNC Libraries(2020)10.17615/vf4k-5s65

Top 100%

0DataRank

Top 100%0 citations

Michel Garneau, Jianmin Duan, Denis Fourches, Alexander Tropsha, Alexander Sedykh +3 more

Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome

UNC Libraries(2020)10.17615/wca1-1b08

N/A

0DataRank · unranked

0 citations

Ralph Edwards, Alexander Tropsha, Yen Low, G. Niklas Norén, Xiaoling Zang +4 more

Predicting Binding Affinity of CSAR Ligands Using Both Structure-Based and Ligand-Based Approaches

UNC Libraries(2020)10.17615/733t-6r44

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Eugene Muratov, Feng Ding, Denis Fourches, Alexander Tropsha

Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species

UNC Libraries(2020)10.17615/ak24-6t77

Top 100%

0DataRank

Top 100%0 citations

Denis Fourches, J. Z. Reed, Julie C. Barnes, Nicola C. Day, Alexander Tropsha +1 more

Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization

UNC Libraries(2020)10.17615/x095-3q76

N/A

0DataRank · unranked

0 citations

Carolina Horta Andrade, Eugene Muratov, Vinícius M. Alves, Alexander Tropsha, Denis Fourches +2 more

Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

Figshare(2020)10.17615/d9xv-0d77

N/A

0DataRank · unranked

0 citations

Tetsuro Urushidani, Yohsuke Minowa, Ivan Rusyn, В. Н. Кузьмин, Denis Fourches +8 more

HTS navigator: freely accessible cheminformatics software for analyzing high-throughput screening data

UNC Libraries(2020)10.17615/a39s-h534

N/A

0DataRank · unranked

0 citations

Denis Fourches, Alexander Tropsha, Maria F. Sassano, Bryan L. Roth

Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity

UNC Libraries(2020)10.17615/p7aa-4h44

N/A

0DataRank · unranked

0 citations

Vinícius M. Alves, Carolina Horta Andrade, Eugene Muratov, Rodolpho C. Braga, Luciano M. Lião +3 more

Modeling Liver-Related Adverse Effects of Drugs Using kNN QSAR Method

UNC Libraries(2020)10.17615/n8p2-4851

N/A

0DataRank · unranked

1 citations

Hao Zhu, Denis Fourches, Ivan Rusyn, Alexander Tropsha, Amie D. Rodgers

QSAR Modeling: Where Have You Been? Where Are You Going To?

UNC Libraries(2020)10.17615/xjsa-2e26

N/A

0DataRank · unranked

1 citations

Alexandre Varnek, Denis Fourches, Richard, Ann, Lothar Terfloth, M Cronin +15 more

Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite

Environmental Health Perspectives(2021)10.1289/ehp10369

N/A

0DataRank · unranked

31 citations

Agnes L. Karmaus, Jeremy Fitzpatrick, Grace Patlewicz, Prachi Pradeep, Domenico Alberga +95 more

Data Set Modelability by QSAR

Figshare(2021)10.17615/c343-bx61

N/A

0DataRank · unranked

0 citations

Eugene Muratov, Alexander Golbraikh, Denis Fourches, Alexander Tropsha

Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.23.525251

N/A

0DataRank · unranked

12 citations

Joshua Yu, Arundhati Suresh, Zachary J. Gale-Day, Matthew G. Alteen, Amanda S. Woo +9 more

Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research

UNC Libraries(2020)10.17615/sqys-za24

N/A

0DataRank · unranked

2 citations

Eugene Muratov, Alexander Tropsha, Denis Fourches

A critical overview of computational approaches employed for COVID-19 drug discovery

UNC Libraries(2024)10.17615/bwe6-fp72

N/A

0DataRank · unranked

5 citations

Kenneth M. Merz, Matthew H. Todd, José L. Medina‐Franco, Sean Ekins, Alexey Zakharov +14 more

Chemistry-Wide Association Studies (CWAS): A Novel Framework for Identifying and Interpreting Structure-Activity Relationships

INDIGO (University of Illinois at Chicago)(2024)10.17615/37wt-zh83

N/A

0DataRank · unranked

0 citations

Yen Low, Ivan Rusyn, Eugene Muratov, Vinícius M. Alves, Alexander Tropsha +3 more

Predicting Adverse Drug Effects from Literature- and Database-Mined Assertions

UNC Libraries(2024)10.17615/6st6-6510

N/A

0DataRank · unranked

0 citations

Mary K. La, Alexander Tropsha, Eugene Muratov, Denis Fourches, Alexander Sedykh

Integrative statistical methods for exposure mixtures and health

The Annals of Applied Statistics(2020)10.1214/20-aoas1364

N/A

0DataRank · unranked

7 citations

Yawen Guan, Denis Fourches, Joshua L. Warren, Stefanie Sarnat, Howard H. Chang +1 more

Structure-Based Virtual Screening of Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) as Endocrine Disruptors of Androgen Receptor Activity Using Molecular Docking and Machine Learning

ChemRxiv(2020)10.26434/chemrxiv.11886702

N/A

0DataRank · unranked

0 citations

Phum Tachachartvanich, Denis Fourches, Anatoly A. Soshilov, Jennifer C.Y. Hsieh, Michele A. La Merrill +3 more

Cheminformatics Analysis of Fluoroquinolones and their Inhibition Potency Against Four Pathogens

Molecular Informatics(2020)10.1002/minf.202000215

N/A

0DataRank · unranked

2 citations

Christian Melander, Denis Fourches, Alexandre Borrel

Denis Fourches

Indexed papers

Top data-sharing exemplar

Papers