David M. Margolis

University of North Carolina at Chapel Hill

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.688Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Association Between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death in Nonhospitalized Adults With Mild-to-Moderate COVID-19

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad287

Top 29%

0.688DataRank

Top 29%7 citations

Kara W Chew, Joseph J. Eron, Jonathan Z. Li, Mauricio Pinilla, Carlee Moser +32 more

Papers

Driven by 135 papers — median percentile 0. Top paper: “Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women”.

Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women

New England Journal of Medicine(2021)10.1056/nejmoa2101016

N/A

8.3DataRank · unranked

869 citations

Deborah Donnell, Meredith E. Clement, Brett Hanscom, Leslie Cottle, Lara E. Coelho +60 more

Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat

The Journal of Infectious Diseases(2021)10.1093/infdis/jiab487

N/A

1.2DataRank · unranked

52 citations

Katherine S. James, Marina Tuyishime, Shane D. Falcinelli, Sarah Joseph, Matthew Moeser +18 more

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

Cell(2020)10.1016/j.cell.2020.05.042

N/A

1.1DataRank · unranked

1647 citations

Kenichi Okuda, Caitlin E. Edwards, David R. Martinez, Takanori Asakura, Kenneth H. Dinnon +38 more

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

Science(2020)10.1126/science.abe8499

N/A

1.0DataRank · unranked

998 citations

S. Chiba, Peter Halfmann, Camille Ehré, Makoto Kuroda, Kenneth H. Dinnon +21 more

Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19

Annals of Internal Medicine(2023)10.7326/m22-3428

N/A

0.785DataRank · unranked

31 citations

Kara W Chew, Mark J Giganti, Carlee Moser, Mauricio Pinilla, David A. Wohl +76 more

Curing HIV: Seeking to Target and Clear Persistent Infection

Cell(2020)10.1016/j.cell.2020.03.005

N/A

0.785DataRank · unranked

186 citations

Nancie M. Archin, Myron S. Cohen, Joseph J. Eron, Guido Ferrari, J. Víctor García +7 more

CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption

Nature Medicine(2020)10.1038/s41591-020-0782-y

N/A

0.701DataRank · unranked

106 citations

Shari N. Gordon, Chi Ngai Chan, Hong Wang, Emily Lindemuth, Cristin M. Galardi +25 more

Association Between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death in Nonhospitalized Adults With Mild-to-Moderate COVID-19

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad287

Top 29%

0.688DataRank

Top 29%7 citations

Kara W Chew, Joseph J. Eron, Jonathan Z. Li, Mauricio Pinilla, Carlee Moser +32 more

Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral Therapy

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa718

N/A

0.657DataRank · unranked

79 citations

Kayla W. Kilpatrick, Jenna Read, Ross Murtagh, Brigitte Allard, Simon Ghofrani +11 more

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA

Journal of Virology(2020)10.1128/jvi.01986-20

N/A

0.644DataRank · unranked

72 citations

Shane D. Falcinelli, Elina Stoffel, Jenna Read, Ross Murtagh, Thiago Y. Oliveira +13 more

HIV post-treatment controllers have distinct immunological and virological features

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2218960120

N/A

0.628DataRank · unranked

65 citations

Xiaoming Sun, Yijia Li, Meghan Melberg, Daniela Moïsi, Rachel Gottlieb +23 more

The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy

The Journal of Infectious Diseases(2024)10.1093/infdis/jiad423

N/A

0.483DataRank · unranked

13 citations

Patrick J. Hanley, Shane D. Falcinelli, JoAnn Kuruc, Susan Pedersen, Jennifer Kirchherr +16 more

Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control

Journal of Virology(2022)10.1128/jvi.01254-22

N/A

0.449DataRank · unranked

19 citations

Holly Anne Martin, Yijia Li, Sushama Telwatte, Gayatri Nikhila Kadiyala, Meghan Melberg +12 more

Silk fibers assisted long-term 3D culture of human primary urinary stem cells via inhibition of senescence-associated genes: Potential use in the assessment of chronic mitochondrial toxicity

Materials Today Advances(2022)10.1016/j.mtadv.2022.100261

N/A

0.434DataRank · unranked

17 citations

Sunil George, Xiaoyan Leng, Michael A. Ihnat, Jian‐xing Ma, Guochun Jiang +4 more

Dominant CD4+ T cell receptors remain stable throughout antiretroviral therapy-mediated immune restoration in people with HIV

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101268

N/A

0.406DataRank · unranked

14 citations

Ann Marie Weideman, Jolene S. Ranek, Gatphan Atassi, JoAnn Kuruc, Adaora A. Adimora +10 more

Bispecific antibody-derived molecules to target persistent HIV infection

Journal of Virus Eradication(2022)10.1016/j.jve.2022.100083

N/A

0.406DataRank · unranked

14 citations

Guido Ferrari, David M. Margolis, Jeffrey L. Nordstrom

Depletion of HIV reservoir by activation of ISR signaling in resting CD4+ T cells

iScience(2022)10.1016/j.isci.2022.105743

N/A

0.345DataRank · unranked

9 citations

Lilly Wong, Yuyang Tang, Brigitte Allard, Katherine S. James, George R. Thompson +8 more

Long‐term outcomes after unrelated donor transplantation for severe sickle cell disease on the BMT CTN 0601 trial

American Journal of Hematology(2024)10.1002/ajh.27251

N/A

0.312DataRank · unranked

7 citations

Jianqun Kou, Martin Andreánsky, Monica Bhatia, Joel A. Brochstein, Sonali Chaudhury +15 more

Post-acute COVID-19 outcomes including participant-reported long COVID: amubarvimab/romlusevimab versus placebo in the ACTIV-2 trial

EClinicalMedicine(2024)10.1016/j.eclinm.2024.102787

N/A

0.208DataRank · unranked

3 citations

Carlee Moser, Nikolaus Jilg, Justin Ritz, David A. Wohl, Jonathan Z. Li +89 more

Evaluation of a COVID-19 convalescent plasma program at a U.S. academic medical center

PLoS ONE(2022)10.1371/journal.pone.0277707

N/A

0.165DataRank · unranked

2 citations

Matt Gilleskie, Chih-Huan Lu, Andrew Gilmore, Mariama Evans, Bridget Nelson +18 more

The persistent pool of HIV-1-infected cells is formed episodically during untreated infection

Journal of Virology(2024)10.1128/jvi.00979-24

N/A

0.165DataRank · unranked

2 citations

Matthew Moeser, Amy Sondgeroth, E. Spielvogel, Brian Richardson, Deelan Doolabh +13 more

Acute HIV-1 Infection in the Southeastern United States: A Cohort Study

UNC Libraries(2020)10.17615/334w-n031

Top 100%

0DataRank

Top 100%0 citations

JoAnn Kuruc, Guido Ferrari, Mehri S. Mckellar, Joseph J. Eron, Charles B. Hicks +7 more

Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection

UNC Libraries(2020)10.17615/2ek5-wr30

N/A

0DataRank · unranked

0 citations

Ronald J. Bosch, Daniel Parker, Manzoor Cheema, Myron S. Cohen, Ann Wiegand +4 more

No Effect of Raltegravir Intensification on Viral Replication Markers in the Blood of HIV-1–Infected Patients Receiving Antiretroviral Therapy

UNC Libraries(2020)10.17615/cqt4-n048

N/A

0DataRank · unranked

0 citations

Rajesh T. Gandhi, John W. Mellors, Lu Zheng, Richard DʼAquila, Robert W. Coombs +12 more

Association of HIV neutralizing antibody with lower viral load after treatment interruption in a prospective trial (A5170)

UNC Libraries(2020)10.17615/e30m-2v10

N/A

0DataRank · unranked

0 citations

Nicole Close, Zhaohui Su, Jerome H. Kim, Robert Paris, Cecilia Shikuma +3 more

Eradication Therapies for HIV Infection: Time to Begin Again

UNC Libraries(2020)10.17615/r6y6-tg81

N/A

0DataRank · unranked

0 citations

David M. Margolis

Histone deacetylase inhibitors and HIV latency

UNC Libraries(2020)10.17615/f1ty-8020

N/A

0DataRank · unranked

0 citations

David M. Margolis

Emerging strategies to deplete the HIV reservoir

UNC Libraries(2020)10.17615/r0nj-5308

N/A

0DataRank · unranked

0 citations

Nancie M. Archin, David M. Margolis

Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α–producing and partially matured phenotype

UNC Libraries(2020)10.17615/r5qp-d365

N/A

0DataRank · unranked

0 citations

Linda Rolnitzky, Nina Bhardwaj, Meagan P. O’Brien, Yaming Wang, Rachel Lubong Sabado +6 more

Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells

UNC Libraries(2020)10.17615/6tfn-9g42

N/A

0DataRank · unranked

0 citations

David M. Margolis, Nicholas Bandarenko, Ronald J. Bosch, John M. Coffin, John L. Schmitz +7 more

Curing HIV: Pharmacologic Approaches to Target HIV-1 Latency

UNC Libraries(2020)10.17615/at2w-mf87

N/A

0DataRank · unranked

0 citations

Shailesh K. Choudhary, David M. Margolis

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

UNC Libraries(2020)10.17615/ex85-vx95

N/A

0DataRank · unranked

0 citations

Herbert Dang, Kara S. Keedy, David M. Margolis, Daria J. Hazuda, Amy S. Espeseth +1 more

Dual-Affinity Re-Targeting proteins direct T cell–mediated cytolysis of latently HIV-infected cells

UNC Libraries(2020)10.17615/dpvw-qk63

N/A

0DataRank · unranked

0 citations

Liqin Liu, Cynthia L. Gay, Jennifer Kirchherr, Scott Koenig, Robert E. Parks +24 more

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

UNC Libraries(2020)10.17615/yaw4-y992

N/A

0DataRank · unranked

0 citations

Natalia Soriano-Sarabia, Nancie M. Archin, David M. Margolis, Julia Marsh Sung, Garrido, Carolina

An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

UNC Libraries(2020)10.17615/xy2p-0641

N/A

0DataRank · unranked

0 citations

Nancie M. Archin, Paula C. Soto, Akul Singhania, Celsa A. Spina, Christopher H. Woelk +18 more

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

UNC Libraries(2020)10.17615/t906-m886

N/A

0DataRank · unranked

0 citations

Julia Sung, David M. Margolis, JoAnn Kuruc, Katherine Sholtis, Catherine M. Bollard +4 more

Predictors of residual viremia in patients on long-term suppressive antiretroviral therapy

UNC Libraries(2020)10.17615/30jy-vh84

N/A

0DataRank · unranked

0 citations

Mary F. Kearney, David M. Margolis, Lu Zheng, John W. Mellors, Sarah Read +4 more

Latency reversal and viral clearance to cure HIV-1

UNC Libraries(2020)10.17615/jf1g-1d76

N/A

0DataRank · unranked

0 citations

Daria J. Hazuda, Barton F. Haynes, J. Victor Garcia, David M. Margolis

Expanded Cytotoxic T-cell Lymphocytes Target the Latent HIV Reservoir

UNC Libraries(2020)10.17615/7m10-bw52

N/A

0DataRank · unranked

0 citations

Sharon Lam, Nancie M. Archin, Garrido, Carolina, Julia Sung, David M. Margolis +2 more

Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency

UNC Libraries(2020)10.17615/0r16-dv38

N/A

0DataRank · unranked

0 citations

Nilu Goonetilleke, Erin Stuelke, JoAnn Kuruc, David M. Margolis, Julia Sung +9 more

Polyclonal B Cell Differentiation and Loss of Gastrointestinal Tract Germinal Centers in the Earliest Stages of HIV-1 Infection

UNC Libraries(2020)10.17615/2tyg-me06

N/A

0DataRank · unranked

0 citations

Nathan Vandergrift, Hua‐Xin Liao, Kwan‐Ki Hwang, Daniel C. Parker, George M. Shaw +20 more

Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid

UNC Libraries(2020)10.17615/86nj-jr45

N/A

0DataRank · unranked

0 citations

Daria J. Hazuda, Manzoor Cheema, Daniel Parker, Nancie M. Archin, David M. Margolis +1 more

Therapy for Persistent HI

UNC Libraries(2020)10.17615/9mht-kj52

N/A

0DataRank · unranked

0 citations

David M. Margolis, Kara S. Keedy

Change-point models to estimate the limit of detection

UNC Libraries(2020)10.17615/1d03-z773

N/A

0DataRank · unranked

0 citations

Michael G. Hudgens, Haitao Chu, Abigail C. Lees, Joseph G. Ibrahim, David M. Margolis +1 more

Dose-responsive gene expression in suberoylanilide hydroxamic acid-treated resting CD4+ T cells

UNC Libraries(2020)10.17615/29tc-n011

N/A

0DataRank · unranked

0 citations

Akul Singhania, Nadejda Beliakova‐Bethell, Brian Reardon, Christopher H. Woelk, Douglas Richman +2 more

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

UNC Libraries(2020)10.17615/49bm-cj85

N/A

0DataRank · unranked

0 citations

Dawn J. Marshall, Eleanor Marshal, Kwan Ki Hwang, Jae Sung Yu, John F. Whitesides +27 more

Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies

UNC Libraries(2020)10.17615/mre9-5k02

N/A

0DataRank · unranked

0 citations

David M. Margolis, Joseph J. Eron, JoAnn Kuruc, Nancie M. Archin, Cynthia L. Gay +6 more

Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART

UNC Libraries(2020)10.17615/fnnq-cv59

N/A

0DataRank · unranked

0 citations

Yang Kuo, Olivia D. Snyder, David M. Margolis, Angela D. M. Kashuba, Paul W. Denton +12 more

Selective Targeting of the Repressive Transcription Factors YY1 and cMyc to Disrupt Quiescent Human Immunodeficiency Viruses

UNC Libraries(2020)10.17615/x7tn-7a65

N/A

0DataRank · unranked

0 citations

Kirston Barton, David M. Margolis

Antiretroviral Therapy Initiated During Acute HIV Infection Fails to Prevent Persistent T-Cell Activation

UNC Libraries(2020)10.17615/aagn-qc46

N/A

0DataRank · unranked

0 citations

Anna B. Cope, Guido Ferrari, JoAnn D. Kuruc, Charles B. Hicks, David M. Margolis +5 more

Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection

UNC Libraries(2020)10.17615/d8e0-cw37

N/A

0DataRank · unranked

0 citations

Yanling Zhang, Edward B. Holson, Nancie M. Archin, Kara S. Keedy, David M. Margolis +4 more

Inhibition of HIV Fusion with Multivalent Gold Nanoparticles

INDIGO (University of Illinois at Chicago)(2020)10.17615/y50t-7e15

N/A

0DataRank · unranked

0 citations

Christian Melander, Mary-Catherine Bowman, David M. Margolis, Daniel L. Feldheim, Christopher J. Ackerson +1 more

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

UNC Libraries(2020)10.17615/2xk9-k921

N/A

0DataRank · unranked

0 citations

Matthew A. Szaniawski, Vicente Planelles, David M. Margolis, Ryan M. Van Wagoner, Chris M. Ireland +8 more

Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection

UNC Libraries(2020)10.17615/k5pf-hk04

N/A

0DataRank · unranked

0 citations

Guido Ferrari, Haitao Chu, Cynthia L. Gay, Susan A. Fiscus, Joe Sebastian +9 more

Quantification of the Latent HIV-1 Reservoir Using Ultra Deep Sequencing and Primer ID in a Viral Outgrowth Assay

UNC Libraries(2020)10.17615/0339-qq60

N/A

0DataRank · unranked

0 citations

Michael G. Hudgens, Shuntai Zhou, Nancie M. Archin, Pedro L. Baldoni, E. Spielvogel +3 more

Translational challenges in targeting latent HIV infection and the CNS reservoir problem

UNC Libraries(2020)10.17615/37qq-d914

N/A

0DataRank · unranked

0 citations

Garrido, Carolina, David M. Margolis

Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model

UNC Libraries(2020)10.17615/jzgk-jq02

N/A

0DataRank · unranked

0 citations

Douglas D. Richman, Laura Martins, Vicente Planelles, Bastiaan Moesker, Christopher H. Woelk +5 more

Gold nanoparticles to improve HIV drug delivery

UNC Libraries(2020)10.17615/5f5y-es57

N/A

0DataRank · unranked

0 citations

Daniel C. Whitehead, Carrie A. Simpson, Carly J. Carter, Daniel L. Feldheim, Noelle Dahl +7 more

The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial

UNC Libraries(2020)10.17615/tvqk-k182

N/A

0DataRank · unranked

0 citations

Rajesh T. Gandhi, Sarah Jane Palmer, Ronald J. Bosch, John M. Coffin, Ann Wiegand +12 more

International AIDS Society global scientific strategy: towards an HIV cure 2016

UNC Libraries(2020)10.17615/7q2b-ex16

N/A

0DataRank · unranked

0 citations

Éric A Cohen, Guido Silvestri, Laurindo Garcia, Janet D. Siliciano, Jeffrey Taylor +50 more

Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication

Nature Immunology(2021)10.1038/s41590-021-00898-1

N/A

0DataRank · unranked

111 citations

Qi Wang, Khader Ghneim, Li Wang, Elena Rampanelli, Elizabeth Holley-Guthrie +10 more

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

PLoS Pathogens(2021)10.1371/journal.ppat.1009346

N/A

0DataRank · unranked

56 citations

Samuel D. Burgos, Jackson J. Peterson, Sara R. Selitsky, Anne‐Marie W. Turner, Lindsey I. James +6 more

Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals

mSphere(2021)10.1128/msphere.00275-21

N/A

0DataRank · unranked

48 citations

Natasa Giallourou, D. Ryan Bhowmik, Yixuan J. Hou, A. Martin Lerner, David R. Martinez +19 more

CD8 Lymphocyte Depletion Enhances the Latency Reversal Activity of the SMAC Mimetic AZD5582 in ART-Suppressed Simian Immunodeficiency Virus-Infected Rhesus Macaques

Journal of Virology(2021)10.1128/jvi.01429-20

N/A

0DataRank · unranked

31 citations

Laura E. Liao, Alyssa D. Brooks, Ruian Ke, Cameron Mattingly, Nils Schoof +14 more

Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52

iScience(2021)10.1016/j.isci.2021.103649

N/A

0DataRank · unranked

19 citations

Morgan Dewey, Li Wang, Shane D. Falcinelli, Lilly Wong, Yuyang Tang +6 more

Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size

Clinical Infectious Diseases(2021)10.1093/cid/ciab587

N/A

0DataRank · unranked

12 citations

Catherine Riou, Sarah Joseph, Nancie M. Archin, David M. Margolis, Alan S. Perelson +12 more

Defining Stable Reference Genes in HIV Latency Reversal Experiments

Journal of Virology(2021)10.1128/jvi.02305-20

N/A

0DataRank · unranked

9 citations

Gabrielle Streeter, Kena J. Lemu, Katherine S. James, Simon Ghofrani, Brigitte Allard +4 more

Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART® Molecules

Frontiers in Immunology(2021)10.3389/fimmu.2021.710273

N/A

0DataRank · unranked

7 citations

Amir Dashti, Katelyn Faircloth, Shalini Jha, Jeffrey L. Nordstrom, Barton F. Haynes +5 more

Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals

UNC Libraries(2021)10.17615/8hx6-th21

N/A

0DataRank · unranked

1 citations

Aaron Lerner, Caleb Cornaby, Ralph S. Baric, Natasa Giallourou, Lakshmanane Premkumar +19 more

Sex disparities and neutralizing antibody durability to SARS-CoV-2 infection in convalescent individuals

medRxiv(2021)10.1101/2021.02.01.21250493

N/A

0DataRank · unranked

20 citations

Natasa Giallourou, D. Ryan Bhowmik, Yixuan J. Hou, A. Martin Lerner, David R. Martinez +19 more

Large-scale allosteric switch in the 7SK RNA regulates transcription in response to growth and stress

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.16.460563

N/A

0DataRank · unranked

1 citations

Anne‐Marie W. Turner, J. Winston Arney, Irfana Saleem, Chase A. Weidmann, David M. Margolis +3 more

Combined approaches for HIV cure

UNC Libraries(2021)10.17615/mkg6-xa58

N/A

0DataRank · unranked

0 citations

David M. Margolis, Daria J. Hazuda

Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP

Molecular Cell(2022)10.1016/j.molcel.2022.02.009

N/A

0DataRank · unranked

116 citations

Anne‐Marie W. Turner, J. Winston Arney, Irfana Saleem, Chase A. Weidmann, David M. Margolis +3 more

Microglia-Specific Promoter Activities of HEXB Gene

Frontiers in Cellular Neuroscience(2022)10.3389/fncel.2022.808598

N/A

0DataRank · unranked

20 citations

Lilly Wong, Kendra Ellis, Brittany Bodnar, Sami Saribas, Julia Ting +10 more

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

Pharmaceutics(2022)10.3390/pharmaceutics14051042

N/A

0DataRank · unranked

15 citations

Kalyani Jambunathan, Guochun Jiang, David M. Margolis, Iris Leng, Michael A. Ihnat +4 more

Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants

Journal of Virology(2022)10.1128/jvi.01699-21

N/A

0DataRank · unranked

11 citations

Veronica Obregon-Perko, Brianna Williams, Danielle Oliver, Ferzan Uddin, Margaret Neja +16 more

A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV infected cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.09.491199

N/A

0DataRank · unranked

7 citations

Catherine A. Lewis, Samuel D. Burgos, Manickam Ashokkumar, Yinyan Xu, Allison A Rowley +8 more

Outcomes of convalescent plasma with defined high- versus lower-neutralizing antibody titers against SARS-CoV-2 among hospitalized patients: CoronaVirus Inactivating Plasma (CoVIP), double-blind phase 2 study

medRxiv(2022)10.1101/2022.04.29.22274387

N/A

0DataRank · unranked

2 citations

Alena J. Markmann, Bridget Nelson, Jessica Keys, Heather Root, Heather Henderson +16 more

Crotonate sensitizes IAPi in the disruption of latent HIV by modulating the ncNF‐κB signaling pathway at the step of p100 cleavage into p52

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.0r808

N/A

0DataRank · unranked

0 citations

Dajiang Li, Shane D. Falcinelli, Lilly Wong, Yuyang Tang, Edward P. Browne +3 more

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

UNC Libraries(2022)10.17615/snwa-sm18

N/A

0DataRank · unranked

0 citations

Jian-xing Ma, Huifen Ding, Kalyani Jambunathan, Guochun Jiang, Yuanyuan Zhang +4 more

Integrated single-cell multiomic analysis of HIV latency reversal reveals novel regulators of viral reactivation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.26.501558

N/A

0DataRank · unranked

0 citations

Jackson J. Peterson, Yuriko Harigaya, David M. Murdoch, David M. Margolis, Alex Oesterling +5 more

Outcomes of Convalescent Plasma with Defined High versus Lower Neutralizing Antibody Titers against SARS-CoV-2 among Hospitalized Patients: CoronaVirus Inactivating Plasma (CoVIP) Study

UNC Libraries(2022)10.17615/27bq-xc46

N/A

0DataRank · unranked

0 citations

Heather Henderson, Alena J. Markmann, JoAnn Kuruc, Anne M. Lachiewicz, Luther A. Bartelt +16 more

Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy

Journal of Clinical Investigation(2023)10.1172/jci167417

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147 citations

Antoine Chaillon, Sara Gianella, Lilly Wong, Dajiang Li, Theresa L. Simermeyer +23 more

AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques

Nature Medicine(2023)10.1038/s41591-023-02570-7

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0DataRank · unranked

47 citations

Sophia Sukkestad, Anna M. Horner, Margaret Neja, Zain Siddiqi, Chevaughn Waller +24 more

A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells

Cell chemical biology(2023)10.1016/j.chembiol.2023.11.009

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30 citations

Catherine A. Lewis, Samuel D. Burgos, Manickam Ashokkumar, Yinyan Xu, Allison A. Rowley +8 more

CD8+ lymphocytes do not impact SIV reservoir establishment under ART

Nature Microbiology(2023)10.1038/s41564-022-01311-9

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0DataRank · unranked

19 citations

WANG JIN, Emily J. Fray, Andrew Kam Ho Wong, Mithra R. Kumar, Elizabeth Ferrer +24 more

A truncated HIV Tat demonstrates potent and specific latency reversal activity

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.00417-23

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15 citations

Marion Pardons, Erik Nijs, Nick Verheyen, Koen Dockx, Christel Van den Eynde +13 more

Impact of Cannabis Use on Immune Cell Populations and the Viral Reservoir in People With HIV on Suppressive Antiretroviral Therapy

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad364

N/A

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14 citations

Alicia D. Volkheimer, Lesia Semenova, Ethan Wu, Alexander Richardson, Manickam Ashokkumar +6 more

Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice

PLoS Pathogens(2023)10.1371/journal.ppat.1011824

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12 citations

Chandrav De, Rae Ann Spagnuolo, Nurjahan Begum, Shane D. Falcinelli, Nancie M. Archin +6 more

Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA

Journal of Virus Eradication(2023)10.1016/j.jve.2023.100315

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4 citations

Katharine J. Bar, T. Burdo, Marina Caskey, Ann Chahroudi, M. Farzan +10 more

HIVepsilon-seq—scalable characterization of intact persistent proviral HIV reservoirs in women

Journal of Virology(2023)10.1128/jvi.00705-23

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0DataRank · unranked

1 citations

James M. Ferguson, Ira W. Deveson, Shane D. Falcinelli, Katherine S. James, Jennifer Kirchherr +10 more

Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.16.567386

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0DataRank · unranked

1 citations

Yingfan Wang, Shane D. Falcinelli, Nancie M. Archin, Alicia D. Volkheimer, David M. Margolis +5 more

The histone methyltransferase SETD2 regulates HIV expression and latency through a post-transcriptional mechanism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.15.571871

N/A

0DataRank · unranked

0 citations

Airlie Ward, Anne‐Marie W. Turner, Jackson J. Peterson, Ann Emery, Arturo SR Longoria +4 more

Analysis of the effect of HDAC inhibitors on the formation of the HIV reservoir

mBio(2024)10.1128/mbio.01632-24

N/A

0DataRank · unranked

14 citations

Manse Kim, Andrew Soper, Martina Kovářová, Rae Ann Spagnuolo, Nurjahan Begum +9 more

Nanoparticle delivery of Tat synergizes with classical latency reversal agents to express HIV antigen targets

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.00201-24

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8 citations

Shane D. Falcinelli, Jackson J. Peterson, Ellen Van Gulck, Brigitte Allard, Jennifer Kirchherr +6 more

Characterization of Treatment Resistance and Viral Kinetics in the Setting of Single-Active Versus Dual-Active Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae192

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7 citations

Rinki Deo, Teresa H. Evering, Kara W Chew, Mark J Giganti, Carlee Moser +17 more

Rapid viral suppression using integrase inhibitors during acute HIV-1 infection

Journal of Antimicrobial Chemotherapy(2024)10.1093/jac/dkae391

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6 citations

Jessica Keys, Lindsey M. Filiatreau, Kara McGee, JoAnn D. Kuruc, Guido Ferrari +5 more

Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner?

Pathogens and Immunity(2024)10.20411/pai.v8i2.665

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4 citations

Michael R. Betts, Mathias Lichterfeld, Michaela Müller‐Trutwin, David M. Margolis, Katharine J. Bar +8 more

The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus

PLoS Pathogens(2024)10.1371/journal.ppat.1011974

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7 citations

Melissa-Rose Abrahams, Matthew Moeser, Lynn Tyers, Nancie M. Archin, Amy Sondgeroth +12 more

Sequence Analysis of Inducible, Replication-Competent Virus Reveals No Evidence of HIV-1 Evolution During Suppressive Antiviral Therapy, Indicating a Lack of Ongoing Viral Replication

Open Forum Infectious Diseases(2024)10.1093/ofid/ofae212

N/A

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5 citations

Amy Sondgeroth, Yinyan Xu, Joanna Warren, Shuntai Zhou, Maria Gilleece +9 more

Advancing Toward a Human Immunodeficiency Virus Cure

Infectious Disease Clinics of North America(2024)10.1016/j.idc.2024.06.001

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0DataRank · unranked

5 citations

David M. Margolis

A novel high-throughput microwell outgrowth assay for HIV-infected cells

Journal of Virology(2024)10.1128/jvi.01798-23

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4 citations

Nancie M. Archin, Anne‐Marie W. Turner, Sarah Joseph, Matthew Moeser, David M. Margolis +2 more

Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy

eLife(2024)10.7554/elife.94899

N/A

0DataRank · unranked

4 citations

Yingfan Wang, Shane D. Falcinelli, Nancie M. Archin, Alicia D. Volkheimer, David M. Margolis +5 more

Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal

Figshare(2024)10.17615/bsgz-rc06

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0DataRank · unranked

0 citations

Katherine S. James, Daniel Winecoff, Frances Potjewyd, Lindsey I. James, Nancie M. Archin +6 more

Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52

UNC Libraries(2024)10.17615/8y53-ag31

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0DataRank · unranked

0 citations

Guochun Jiang, Dajiang Li, David M. Margolis, Nancie M. Archin, Xi Chen +6 more

Viral and Symptom Rebound Following Anti–Severe Acute Respiratory Syndrome Coronavirus 2 Monoclonal Antibody Therapy in a Randomized Placebo-Controlled Trial

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae501

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0DataRank · unranked

0 citations

Brooke McGinley, Carlee Moser, Jonathan Z. Li, Teresa H. Evering, Justin Ritz +42 more

Rapid viral suppression using integrase inhibitors during acute HIV-1 infection

UNC Libraries(2024)10.17615/00r2-yy40

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0DataRank · unranked

0 citations

Guido Ferrari, Kara McGee, JoAnn D. Kuruc, Joseph J. Eron, Lindsey M. Filiatreau +5 more

The role of Tat in HIV latency and reactivation

Frontiers in Immunology(2025)10.3389/fimmu.2025.1650385

N/A

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7 citations

Edward P. Browne, David M. Margolis

Association Between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death in Nonhospitalized Adults With Mild-to-Moderate COVID-19

UNC Libraries(2025)10.17615/jgjx-bf38

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ACTIV- A Study Team, William A. Fischer, Jonathan Z. Li, Kara W Chew, Arzhang Cyrus Javan +12 more

Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19

UNC Libraries(2025)10.17615/ryrv-wq75

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0DataRank · unranked

0 citations

Yan Li, Jonathan Z. Li, Rachel Bender Ignacio, Kara W Chew, Bharat Mocherla +23 more

Single cell multiomic analysis of the impact of Delta-9-tetrahydrocannabinol on HIV infected CD4 T cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.02.657468

N/A

0DataRank · unranked

0 citations

Rong-song GE, Alicia D. Volkheimer, David M. Margolis, Quefeng Li, Yuchao Jiang +3 more

The persistent pool of HIV-1-infected cells is formed episodically during untreated infection.

UNC Libraries(2025)10.17615/9zn7-gt17

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0 citations

Ann Emery, Olivia D Council, Amy Sondgeroth, Bonnie E. Shook‐Sa, Sergei L. Kosakovsky Pond +14 more

The role of Tat in HIV latency and reactivation

UNC Libraries(2025)10.17615/jcna-ap30

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0 citations

David M. Margolis, Edward P. Browne

HIV post-treatment controllers have distinct immunological and virological features

UNC Libraries(2025)10.17615/aeyv-ay79

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0 citations

David M. Margolis, Paul A. Volberding, Joseph J. Eron, Jeffrey M. Jacobson, Rachel Gottlieb +23 more

The role of Vpr in a primary CD4+ T-cell model of HIV-1 latency 3672

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1444

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0DataRank · unranked

0 citations

David M. Margolis, Edward P. Browne, Catherine A. Lewis

In Vitro Techniques for Studies of HIV-1 Promoter Activity

HIV Protocols10.1385/0-89603-369-4:197

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0 citations

David M. Margolis, Fabio Romerio

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Nature(2020)10.1038/s41586-020-1946-0

N/A

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196 citations

Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp +23 more

Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo

Nature(2020)10.1038/s41586-020-1951-3

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319 citations

Maud Mavigner, Gavin C. Sampey, Alyssa D. Brooks, Rae Ann Spagnuolo, David M. Irlbeck +38 more

Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa298

N/A

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45 citations

Bonnie E. Shook‐Sa, Morgan Dewey, Sumati Sridhar, Jenna Read, Jennifer Kirchherr +15 more

Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection

Scientific Reports(2020)10.1038/s41598-020-61878-3

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47 citations

JoAnn Kuruc, Shane D. Falcinelli, Joanna Warren, Sarah A. Reifeis, Jennifer Kirchherr +18 more

Real World Outcomes in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma Receiving Palliative Intent Therapies

Clinical Lymphoma Myeloma & Leukemia(2020)10.1016/j.clml.2020.05.008

N/A

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19 citations

David M. Margolis, Daniel J. Landsburg, Emily C. Ayers

Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat

Journal of Virology(2020)10.1128/jvi.00351-20

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9 citations

Shane D. Falcinelli, Alexey Nefedov, Corin L. Dorfmeier, Guoxin Wu, Morgan Dewey +7 more

Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies

Journal of Clinical Investigation(2020)10.1172/jci135557

N/A

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38 citations

Carolina Garrido, Shalini Jha, Matt Moeser, Dieter Mielke, Celia C. LaBranche +6 more

SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques

Journal of Virology(2020)10.1128/jvi.00793-20

N/A

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37 citations

Chevaughn Waller, Maud Mavigner, Nils Schoof, Katharine J. Bar, George M. Shaw +12 more

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Frontiers in Immunology(2020)10.3389/fimmu.2020.01971

N/A

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27 citations

Katherine S. James, Jennifer Kirchherr, Brigitte Allard, Caroline Baker, JoAnn Kuruc +4 more

Curing HIV: Seeking to Target and Clear Persistent Infection

UNC Libraries(2020)10.17615/kv3d-q618

N/A

0DataRank · unranked

3 citations

Joseph Eron, Nilu Goonetilleke, Richard Hafner, Ronald Swanstom, Nancie M. Archin +7 more

LB-8. Summary of COVID-Related Impact on Cabotegravir and Rilpivirine Long-Acting (CAB+RPV LA) Dosing Across the Six Ongoing Global Phase IIb and IIIb Clinical Trials

Open Forum Infectious Diseases(2020)10.1093/ofid/ofaa515.1905

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2 citations

Paul Benn, Cynthia McCoig, Sandy Griffith, Krischan J Hudson, Kenneth Sutton +9 more

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

UNC Libraries(2020)10.17615/1qs8-pe15

N/A

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2 citations

Hong Dang, Takafumi Kato, Sarah R. Leist, Aravinda de Silva, Mark J. Cameron +38 more

Measuring the Haystack’s Needles

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa533

N/A

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1 citations

David M. Margolis

H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4 + T Cells

UNC Libraries(2020)10.17615/phj5-gn39

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1 citations

David M. Margolis

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Nature(2020)10.1038/s41586-020-2002-9

N/A

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28 citations

Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp +23 more

The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies

medRxiv(2020)10.1101/2020.05.06.20093377

N/A

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26 citations

Bruno Segovia-Chumbez, Ramesh Jadi, David R. Martinez, Rajendra Raut, Alena J. Markmann +19 more

Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.07.330787

N/A

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10 citations

Shane D. Falcinelli, Elina Stoffel, Jenna Read, Ross Murtagh, Thiago Y. Oliveira +13 more

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.24.220012

N/A

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2 citations

S. Burgos, Jackson J. Peterson, Sara R. Selitsky, Anne‐Marie W. Turner, Lindsey I. James +4 more

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

UNC Libraries(2020)10.17615/dsyq-qr93

N/A

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0 citations

Rachel L. Graham, Rhianna E. Lee, Richard C. Boucher, Noriko Nakajima, Kenneth H. Dinnon +21 more

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