Tyler Jacks

Also affiliated with Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Allen Institute, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

CUT&RUN Supplementary Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

INDIGO (University of Illinois at Chicago)(2023)10.1158/2159-8290.22541093.v1

Top 100%

0DataRank

Top 100%0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Papers

Driven by 57 papers — median percentile 0. Top paper: “The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer”.

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-1825

N/A

9.7DataRank · unranked

292 citations

Chai Bandlamudi, Jessica A. Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi +18 more

Nuclear factor I/B is an oncogene in small cell lung cancer

Genes & Development(2011)10.1101/gad.2046711

N/A

8.2DataRank · unranked

178 citations

Monte M. Winslow, Derek Y. Chiang, Shantanu Banerji, Nicolas Stransky, Talya L. Dayton +10 more

Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.25.267336

N/A

1.6DataRank · unranked

35 citations

Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Payman Yadollahpour, Rahul Mohan +46 more

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

Genes & Development(2022)10.1101/gad.349659.122

N/A

1.2DataRank · unranked

39 citations

Christina M. Cabana, Lindsay M. LaFave, Rodrigo Romero, Sean-Luc Shanahan, Arjun Bhutkar +8 more

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Cell(2010)10.1016/j.cell.2010.06.040

N/A

1.1DataRank · unranked

2079 citations

Mitchell Guttman, David Feldser, Manuel Garber, Magdalena J. Koziol, Daniela Kenzelmann-Broz +11 more

Lung adenocarcinoma promotion by air pollutants

Nature(2023)10.1038/s41586-023-05874-3

N/A

0.998DataRank · unranked

775 citations

Emilia L. Lim, Clare E. Weeden, Claudia Lee, Marcellus Augustine, Kezhong Chen +95 more

The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.25.256214

N/A

0.986DataRank · unranked

10 citations

Peter Winter, Andrew W. Navia, Hannah L. Williams, Alan DenAdel, Radha L. Kalekar +36 more

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

Cell(2021)10.1016/j.cell.2021.11.017

N/A

0.959DataRank · unranked

597 citations

Peter Winter, Andrew W. Navia, Hannah L. Williams, Alan DenAdel, Kristen E. Lowder +42 more

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

Cancer Cell(2020)10.1016/j.ccell.2020.06.012

N/A

0.896DataRank · unranked

393 citations

Matan Hofree, Jason E. Chan, David A. Canner, Katherine Wu, Marianna Trakala +33 more

Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

Cell(2017)10.1016/j.cell.2017.07.028

N/A

0.889DataRank · unranked

374 citations

Tuomas Tammela, Matan Hofree, Jinwook Choi, Nemanja Despot Marjanovic, Seungmin Han +9 more

Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution

Cell(2022)10.1016/j.cell.2022.04.015

N/A

0.879DataRank · unranked

350 citations

Matthew G. Jones, Santiago Naranjo, William M. Rideout, Kyung Hoi Min, Raymond Ho +18 more

Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

Immunity(2021)10.1016/j.immuni.2021.08.026

N/A

0.839DataRank · unranked

267 citations

Rebecca H. Herbst, David A. Canner, Amy Li, Michelle Hillman, Sean-Luc Shanahan +17 more

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Cancer Cell(2021)10.1016/j.ccell.2021.07.007

N/A

0.834DataRank · unranked

259 citations

Laurens J. Lambert, Zackery A. Ely, Nimisha B. Pattada, Arjun J. Bhutkar, George Eng +21 more

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

Cancer Cell(2020)10.1016/j.ccell.2020.06.006

N/A

0.820DataRank · unranked

236 citations

Vinay K. Kartha, Sai Ma, Kevin Meli, Isabella Del Priore, Caleb A. Lareau +13 more

Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data

IEEE Transactions on Visualization and Computer Graphics(2022)10.1109/tvcg.2022.3209378

N/A

0.798DataRank · unranked

22 citations

Robert Krueger, Ajit J. Nirmal, Giorgio Gaglia, J. M. Jessup, Cecily C. Ritch +8 more

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

Cell(2020)10.1016/j.cell.2020.03.062

N/A

0.766DataRank · unranked

164 citations

Jaffarguriqbal Singh, Lauren Lawres, Kimberly Judith Dorans, Cathy Garcia, Daniel B. Burkhardt +24 more

Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

Cell(2021)10.1016/j.cell.2021.08.020

N/A

0.766DataRank · unranked

164 citations

Amanda M. Cruz, Grace E. Crossland, Giorgio Gaglia, Cecily C. Ritch, Sarah E. Blatt +23 more

Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

Cancer Discovery(2021)10.1158/2159-8290.cd-21-0248

N/A

0.714DataRank · unranked

116 citations

Sai Ma, Lindsay M. LaFave, Arjun Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling

Science Translational Medicine(2020)10.1126/scitranslmed.aaw0262

N/A

0.694DataRank · unranked

101 citations

Andrew Warren, Ava P. Soleimany, Peter M.K. Westcott, Justin C. Voog, Carmen Martin-Alonso +5 more

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Cancer Research(2020)10.1158/0008-5472.can-20-1744

N/A

0.624DataRank · unranked

63 citations

Carla P. Concepcion, Caroline G. Fahey, Hasmik Keshishian, Arjun Bhutkar, Christine F. Brainson +23 more

PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

Genes & Development(2017)10.1101/gad.295857.117

N/A

0.617DataRank · unranked

60 citations

Jordan M.E. Bartlebaugh, Yunpeng Liu, Arjun J. Bhutkar, Abraham S. Weintraub, Jason D. Buenrostro +9 more

Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

Cancer Discovery(2021)10.1158/2159-8290.cd-21-0441

N/A

0.581DataRank · unranked

47 citations

Triantafyllia Karakousi, Allison L. Richards, Àlvaro Quintanal-Villalonga, Angeliki Karatza, Rebecca Caeser +20 more

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

Nature Communications(2021)10.1038/s41467-021-25279-y

N/A

0.571DataRank · unranked

44 citations

Carly G.K. Ziegler, Constantine N. Tzouanas, Benjamin E. Mead, Alex M. Jaeger, Andrew W. Navia +10 more

Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

Nature Communications(2021)10.1038/s41467-021-25917-5

N/A

0.561DataRank · unranked

41 citations

A. B. Miller, Lara Meier, Max A. Stockslager, Sheng Rong Ng, Emily King +16 more

Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumour growth and metastasis

10.1101/2024.10.21.619529

N/A

0.489DataRank · unranked

25 citations

Dawei Sun, Kyung Hoi Min, William N. Colgan, Haoyu Wang, Tivadar Török +26 more

A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells

Nature Communications(2022)10.1038/s41467-021-27731-5

N/A

0.483DataRank · unranked

24 citations

Rodrigo Romero, Emma V. Watson, Anthony C. Liang, Megan L. Burger, Peter M.K. Westcott +7 more

Lineage Recording Reveals the Phylodynamics, Plasticity and Paths of Tumor Evolution

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.12.464111

N/A

0.439DataRank · unranked

10 citations

Matthew G. Jones, Santiago Naranjo, William M. Rideout, Kyung Hoi Min, Raymond Ho +18 more

Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.11.503237

N/A

0.312DataRank · unranked

7 citations

Megan L. Burger, Cecily C. Ritch, Danae Rammos, Yang Dai, Grace Crossland +13 more

The CLCF1-CNTFR axis drives an immunosuppressive tumor microenvironment and blockade enhances the effects of established cancer therapies

Research Square(2024)10.21203/rs.3.rs-4046823/v1

N/A

0.241DataRank · unranked

4 citations

Kieren D. Marini, Emma C. Champion, Alex Pui‐Wai Lee, Isabelle Young, Stanley G. Leung +5 more

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

Cancer Cell(2025)10.1016/j.ccell.2025.02.025

N/A

0.165DataRank · unranked

2 citations

Vinay K. Kartha, Sai Ma, Kevin Meli, Isabella Del Priore, Santiago Naranjo +13 more

Longitudinal Single Cell Profiling of Regulatory T Cells Identifies IL-33 as a Driver of Tumor Immunosuppression

SSRN Electronic Journal(2019)10.2139/ssrn.3353223

N/A

0.139DataRank · unranked

1 citations

Rebecca H. Herbst, David A. Canner, Jason M. Schenkel, Jonathan Y. Kim, Michelle Hillman +14 more

Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2102611118

N/A

0DataRank · unranked

136 citations

Elise Alspach, Jeffrey P. Ward, Alexander P. Miceli, Daniele Runci, J. Michael White +8 more

Supplementary Figures S1-S7 from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

INDIGO (University of Illinois at Chicago)(2023)10.1158/2159-8290.22541081.v1

N/A

0DataRank · unranked

0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

CUT&RUN Supplementary Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

INDIGO (University of Illinois at Chicago)(2023)10.1158/2159-8290.22541093.v1

Top 100%

0DataRank

Top 100%0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Single-nucleus RNA-seq of frozen archival primary pancreatic ductal adenocarcinoma uncovers multi-compartment intratumoral heterogeneity associated with neoadjuvant treatment.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.4633

N/A

0DataRank · unranked

0 citations

Hannah I. Hoffman, Orr Ashenberg, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Samouil Farhi +18 more

Bulk ATAC-seq Supplementary Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

(2023)10.1158/2159-8290.22541096

Top 100%

0DataRank

Top 100%0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma

STAR Protocols(2021)10.1016/j.xpro.2021.100583

N/A

0DataRank · unranked

19 citations

Sai Ma, Jonathan Strecker, Tyler Jacks, Lindsay M. LaFave, Jason D. Buenrostro +1 more

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues

Nature(2021)10.1038/s41586-021-04217-4

N/A

0DataRank · unranked

276 citations

Zachary Chiang, Julia W. Morriss, Lindsay M. LaFave, Evan Murray, Isabella Del Priore +10 more

Multiscale profiling of enzyme activity in cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.11.468288

N/A

0DataRank · unranked

5 citations

Jesse D. Kirkpatrick, Cathy S. Wang, Alex M. Jaeger, Susan Su, Santiago Naranjo +5 more

Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma

eLife(2020)10.7554/elife.56782

N/A

0DataRank · unranked

84 citations

Zhaoqi Li, Laura V. Danai, Anna M. Westermark, Alicia M. Darnell, Raphaël Ferreira +14 more

Multiscale profiling of protease activity in cancer

Nature Communications(2022)10.1038/s41467-022-32988-5

N/A

0DataRank · unranked

60 citations

Jesse D. Kirkpatrick, Cathy S. Wang, Alex M. Jaeger, Susan Su, Santiago Naranjo +5 more

Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.01.350918

N/A

0DataRank · unranked

0 citations

A. B. Miller, Lara Meier, Max A. Stockslager, Emily M. King, Sheng Rong Ng +11 more

CUT&RUN Supplementary Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

(2023)10.1158/2159-8290.22541093

Top 100%

0DataRank

Top 100%0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

(2023)10.1158/2159-8290.c.6549551.v1

N/A

0DataRank · unranked

0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Spatially-Resolved Live Cell Tagging and Isolation Using Protected Photoactivatable Cell Dyes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.28.966598

N/A

0DataRank · unranked

0 citations

Carly G.K. Ziegler, Constantine N. Tzouanas, Ben Mead, Alex M. Jaeger, Andrew W. Navia +5 more

Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

(2023)10.1158/2159-8290.c.6549551

N/A

0DataRank · unranked

0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Nature Biotechnology(2023)10.1038/s41587-023-01783-y

N/A

0DataRank · unranked

59 citations

Nicolas Mathey‐Andrews, Santiago Naranjo, Samuel I. Gould, Kim L. Mercer, Gregory A. Newby +22 more

Data from ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice

(2023)10.1158/0008-5472.c.6494688

N/A

0DataRank · unranked

0 citations

Erik Wilker, Margaret E. McLaughlin, Keara Lane, Ram Gowda, Shanie Coven +7 more

Data from Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

(2023)10.1158/2159-8290.c.6549427.v1

N/A

0DataRank · unranked

0 citations

Triantafyllia Karakousi, Allison L. Richards, Àlvaro Quintanal-Villalonga, Angeliki Karatza, Rebecca Caeser +20 more

Data from Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

(2023)10.1158/2159-8290.c.6549427

N/A

0DataRank · unranked

0 citations

Triantafyllia Karakousi, Allison L. Richards, Àlvaro Quintanal-Villalonga, Angeliki Karatza, Rebecca Caeser +20 more

Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment

Nature Genetics(2024)10.1038/s41588-024-01890-9

N/A

0DataRank · unranked

72 citations

Jingyi Cao, Dennis Gong, Mark Gregory, Nicholas J Caldwell, Xunqin Yin +27 more

Inhalable point-of-care urinary diagnostic platform

Science Advances(2024)10.1126/sciadv.adj9591

N/A

0DataRank · unranked

27 citations

Edward K.W. Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D. Kirkpatrick +5 more

Longitudinal Intravascular Antibody Labeling Identified Regulatory T Cell Recruitment as a Therapeutic Target in a Mouse Model of Lung Cancer

The Journal of Immunology(2024)10.4049/jimmunol.2400268

N/A

0DataRank · unranked

12 citations

Nikesh Kunder, Charles Inaku, Natalie B. Hagan, Grace Gibbons, Nicolas Mathey‐Andrews +6 more

NINJA: an inducible genetic model for creating neoantigens in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.09.900894

N/A

0DataRank · unranked

0 citations

Brittany Fitzgerald, Yisi Lu, Mursal Nader, Ivana William, Julie F. Cheung +16 more

The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.26.672505

N/A

0DataRank · unranked

0 citations

Nicole A. Lester, Ella Perrault, Jennifer Su, Dennis Gong, Carina Shiau +33 more

RNA-seq (cell line) Supplementary Data from Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

INDIGO (University of Illinois at Chicago)(2023)10.1158/2159-8290.22541090.v1

Top 100%

0DataRank

Top 100%0 citations

Sai Ma, Lindsay M. LaFave, Arjun J. Bhutkar, Manyuan Liu, Lydia P. DeAngelo +18 more

Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.09.984237

N/A

0DataRank · unranked

2 citations

Zhaoqi Li, Laura V. Danai, Anna M. Westermark, Alicia M. Darnell, Raphaël Ferreira +14 more

Tyler Jacks

Indexed papers

Top data-sharing exemplar

Papers