Lin Xu

The University of Texas Southwestern Medical Center

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.273Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research

JCO Clinical Cancer Informatics(2023)10.1200/cci.23.00104

Top 58%

0.273DataRank

Top 58%4 citations

Qinbo Zhou, Lauren Furman-Cline, Xian Cheng, Danni Luo, Hongyin Lai +21 more

Papers

Driven by 61 papers — median percentile 42. Top paper: “Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice”.

Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice

Nature Medicine(2023)10.1038/s41591-022-02176-5

N/A

4.3DataRank · unranked

169 citations

Miao Cui, Francesco Chemello, Hui Li, Kenian Chen, Wei Tan +8 more

Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1

Cancer Research(2024)10.1158/0008-5472.can-24-1388

N/A

0.924DataRank · unranked

36 citations

Shaked Nir Heyman, Lei Guo, Lydia Flores, Trisha K. Savage, Juan Villarreal +6 more

Deep learning-based prediction of the T cell receptor–antigen binding specificity

Nature Machine Intelligence(2021)10.1038/s42256-021-00383-2

N/A

0.857DataRank · unranked

301 citations

Ze Zhang, James Zhu, Yunguan Wang, Peixin Jiang, Xue Xiao +8 more

Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing

Developmental Cell(2020)10.1016/j.devcel.2020.02.019

N/A

0.781DataRank · unranked

181 citations

Zhaoning Wang, Kenian Chen, Akansha M. Shah, Wei Tan, Lauren Duan +7 more

A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer

Nature Communications(2024)10.1038/s41467-024-44861-8

N/A

0.745DataRank · unranked

25 citations

Ryan R. Kowash, Hai-Cheng Huang, Silvia Siteni, Mingrui Zhu, Kenian Chen +10 more

VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis

Cell Reports(2023)10.1016/j.celrep.2023.112013

N/A

0.636DataRank · unranked

18 citations

Collette A. LaVigne, Lin Xu, Didier Surdez, Joanna Cyrta, Delia Calderon +12 more

Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden

Cancer Cell(2023)10.1016/j.ccell.2023.09.006

N/A

0.617DataRank · unranked

60 citations

Jiwoong Kim, Qing Deng, Biagio Ricciuti, Joao V. Alessi, Buse Eglenen-Polat +12 more

Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture

Cell(2023)10.1016/j.cell.2023.11.008

N/A

0.571DataRank · unranked

44 citations

Enbo Zhang, Leqian Yu, Baiquan Ci, Masahiro Sakurai, Lei Guo +19 more

Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation

Nature Communications(2023)10.1038/s41467-023-37567-w

N/A

0.564DataRank · unranked

42 citations

Jessica S. Hook, Ding Qing, Xue Xiao, Stephen S. Chung, Marcel Mettlen +4 more

Elimination of CaMKIIδ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice

Circulation(2023)10.1161/circulationaha.123.065117

N/A

0.538DataRank · unranked

35 citations

Xurde M. Caravia, Francesco Chemello, Wei Tan, John McAnally, Kenian Chen +5 more

Genomic profiling of subcutaneous patient-derived xenografts reveals immune constraints on tumor evolution in childhood solid cancer

Nature Communications(2023)10.1038/s41467-023-43373-1

N/A

0.406DataRank · unranked

14 citations

Abhik Bandyopadhyay, Laura J. Klesse, Anna Rogojina, Sang H. Chun, Erin Butler +23 more

Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma

Molecular Cell(2024)10.1016/j.molcel.2023.12.010

N/A

0.360DataRank · unranked

10 citations

Yanfeng Zhang, Lei Guo, Hua Zhong, Ling Xie, Jin Zhou +20 more

The MYC-YBX1 Circuit in Maintaining Stem-like Vincristine-Resistant Cells in Rhabdomyosarcoma

Cancers(2023)10.3390/cancers15102788

N/A

0.330DataRank · unranked

8 citations

Kenian Chen, Weiliang Tang, Spencer Stinson, Thao Pham, Yadong Wang +3 more

Assessing next-generation sequencing-based computational methods for predicting transcriptional regulators with query gene sets

Briefings in Bioinformatics(2024)10.1093/bib/bbae366

N/A

0.330DataRank · unranked

8 citations

Xue Xiao, Qiang Zheng, Xinlei Wang, Lin Xu, Zeyu Lu

Net39 protects muscle nuclei from mechanical stress during the pathogenesis of Emery-Dreifuss muscular dystrophy

Journal of Clinical Investigation(2023)10.1172/jci163333

N/A

0.312DataRank · unranked

7 citations

Andres Ramirez-Martinez, Kenian Chen, John McAnally, Chunyu Cai, Mateusz Z. Durbacz +7 more

Cellular Reprogramming by PHF7 Enhances Cardiac Function Following Myocardial Infarction

Circulation(2025)10.1161/circulationaha.124.072733

N/A

0.292DataRank · unranked

6 citations

Matthieu Dos Santos, Kenian Chen, Wei Tan, Svetlana Bezprozvannaya, Peiheng Gan +5 more

Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research

JCO Clinical Cancer Informatics(2023)10.1200/cci.23.00104

Top 58%

0.273DataRank

Top 58%4 citations

Qinbo Zhou, Lauren Furman-Cline, Xian Cheng, Danni Luo, Hongyin Lai +21 more

Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice

Nature Communications(2023)10.1038/s41467-023-39586-z

N/A

0DataRank · unranked

51 citations

Lin Xu, Haiyan Chu, Jun Peng, Anastasia Sacharidou, Hsi-Hsien Hsieh +15 more

Spatial transcriptomic interrogation of the murine bone marrow signaling landscape

Bone Research(2023)10.1038/s41413-023-00298-1

N/A

0DataRank · unranked

51 citations

Conan Juan, Tingsheng Yu, Cedric R. Uytingco, Neda Vishlaghi, Dimitri Sokolowskei +5 more

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization

Nature Communications(2021)10.1038/s41467-021-20987-x

N/A

0DataRank · unranked

28 citations

Yichi Zhang, Kenian Chen, Jiwoong Kim, Bercin Kutluk Cenik, John McAnally +11 more

Regulation of cold-induced thermogenesis by the RNA binding protein FAM195A

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2104650118

N/A

0DataRank · unranked

35 citations

Mengle Shao, Yu An, Svetlana Bezprozvannaya, Shiuhwei Chen, Jiwoong Kim +8 more

CRISPR-Cas9 base editing of pathogenic CaMKIIδ improves cardiac function in a humanized mouse model

Journal of Clinical Investigation(2023)10.1172/jci175164

N/A

0DataRank · unranked

39 citations

Xurde M. Caravia, Leon G. Straub, Damir Alzhanov, Wei Tan, Hui Li +8 more

Itaconate-producing neutrophils regulate local and systemic inflammation following trauma

JCI Insight(2023)10.1172/jci.insight.169208

N/A

0DataRank · unranked

37 citations

Sonya Ostashevskaya-Gohstand, Stefano Comazzetto, Jessica S. Hook, Lei Guo, Neda Vishlaghi +8 more

MB-GAN: Microbiome Simulation via Generative Adversarial Network

GigaScience(2021)10.1093/gigascience/giab005

N/A

0DataRank · unranked

49 citations

Shuang Jiang, Lin Xu, Guanghua Xiao, Yang Xie, Dajiang J. Liu +3 more

Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Nature Communications(2021)10.1038/s41467-021-25653-w

N/A

0DataRank · unranked

151 citations

Ayhan Atmanli, María Gabriela Morales, Wei Tan, Kenian Chen, Xue Xiao +5 more

ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells

Cell Reports(2023)10.1016/j.celrep.2023.113280

N/A

0DataRank · unranked

12 citations

Yi‐Heng Hao, Chunhui Jiang, Seoyeon Jang, Tsung-Cheng Chang, Isabella N. Brown +16 more

Comprehensive characterization of patient-derived xenograft models of pediatric leukemia

iScience(2023)10.1016/j.isci.2023.108171

N/A

0DataRank · unranked

8 citations

Laura J. Klesse, Erin Butler, Jiwoong Kim, He Zhang, Xue Xiao +25 more

Hepatic sialic acid synthesis modulates glucose homeostasis in both liver and skeletal muscle

Molecular Metabolism(2023)10.1016/j.molmet.2023.101812

N/A

0DataRank · unranked

7 citations

Liming Yu, Linzhang Huang, Vivian A. Paschoal, Haiyan Chu, Camila Oliveira de Souza +9 more

Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.07.531525

N/A

0DataRank · unranked

5 citations

Enwei Zhang, Leqian Yu, Baiquan Ci, Lei Guo, Masahiro Sakurai +13 more

Reconstructing Spatial Transcriptomics at the Single-cell Resolution with BayesDeep

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.07.570715

N/A

0DataRank · unranked

5 citations

Lei Dong, Shidan Wang, Zhuoyu Wen, Mingyi Chen, Lin Xu +3 more

Integrating Image and Molecular Profiles for Spatial Transcriptomics Analysis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.18.545488

N/A

0DataRank · unranked

4 citations

Shidan Wang, Lei Guo, Zhuoyu Wen, Liwei Jia, Lin Xu +3 more

Tumor Neoantigenicity Assessment with CSiN Score Incorporates Clonality and Immunogenicity to Predict Immunotherapy Outcomes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.23.917625

N/A

0DataRank · unranked

5 citations

Shidan Wang, Lin Xu, Qinbo Zhou, Nirmish Singla, Jianjun Gao +8 more

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

Bone Research(2024)10.1038/s41413-024-00320-0

N/A

0DataRank · unranked

34 citations

Amy L. Strong, Yuxiao Sun, Lei Guo, Conan Juan, Alec C. Bancroft +13 more

Tumor neoantigenicity assessment with CSiN score incorporates clonality and immunogenicity to predict immunotherapy outcomes

Science Immunology(2020)10.1126/sciimmunol.aaz3199

N/A

0DataRank · unranked

50 citations

Shidan Wang, Lin Xu, Qinbo Zhou, Nirmish Singla, Jianjun Gao +9 more

iIMPACT: integrating image and molecular profiles for spatial transcriptomics analysis

Genome biology(2024)10.1186/s13059-024-03289-5

N/A

0DataRank · unranked

25 citations

Shidan Wang, Lei Guo, Bencong Zhu, Zhuoyu Wen, Liwei Jia +4 more

CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2315925121

N/A

0DataRank · unranked

10 citations

Akansha M. Shah, Víctor López, Vincent S. Tagliabracci, Kenian Chen, Lin Xu +4 more

BayeSMART: Bayesian clustering of multi-sample spatially resolved transcriptomics data

Briefings in Bioinformatics(2024)10.1093/bib/bbae524

N/A

0DataRank · unranked

7 citations

Bencong Zhu, Chen Tang, Ruichen Rong, Ying Ma, Guanghua Xiao +3 more

An interpretable Bayesian clustering approach with feature selection for analyzing spatially resolved transcriptomics data

Biometrics(2024)10.1093/biomtc/ujae066

N/A

0DataRank · unranked

6 citations

Bencong Zhu, Xi Jiang, Lei Guo, Yang Xie, Lin Xu +2 more

BIT: Bayesian Identification of Transcriptional Regulators from Epigenomics-Based Query Region Sets

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.02.597061

N/A

0DataRank · unranked

1 citations

Lin Xu, Xinlei Wang, Zeyu Lu

PGLYRP-1 mediated intracellular peptidoglycan detection promotes mucosal protection

Research Square(2024)10.21203/rs.3.rs-5118704/v1

N/A

0DataRank · unranked

1 citations

Shuyuan Chen, Rachel Putnik, Zhiheng Li, Alka Diwaker, Marina Vasconcelos +12 more

Assessing NGS-based computational methods for predicting transcriptional regulators with query gene sets

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.01.578316

N/A

0DataRank · unranked

0 citations

Xue Xiao, Qiang Zheng, Xinlei Wang, Lin Xu, Zeyu Lu

Cooperative integration of spatially resolved multi-omics data with COSMOS

Nature Communications(2025)10.1038/s41467-024-55204-y

N/A

0DataRank · unranked

40 citations

Xue Xiao, Lei Dong, Chen Tang, Guanghua Xiao, Lin Xu +1 more

PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection

Nature Communications(2025)10.1038/s41467-025-57126-9

N/A

0DataRank · unranked

19 citations

Rachel Putnik, Zhiheng Li, Alka Diwaker, Marina Vasconcelos, Shuzhen Liu +14 more

Genomic Editing of a Pathogenic Sequence Variant in ACTA2 Rescues Multisystemic Smooth Muscle Dysfunction Syndrome in Mice

Circulation(2025)10.1161/circulationaha.125.074218

N/A

0DataRank · unranked

11 citations

Peiheng Gan, Zhi‐Sheng Xu, Hui Li, Lei Guo, Camryn MacDonald +9 more

Secretogranin 2 binds LILRB4 resulting in immunosuppression

Nature Immunology(2025)10.1038/s41590-025-02233-4

N/A

0DataRank · unranked

10 citations

Ryan Yuki Huang, Meng Fang, Yubo He, Jingjing Xie, Xiaoye Liu +13 more

BBOX1 restrains TBK1-mTORC1 oncogenic signaling in clear cell renal cell carcinoma

Nature Communications(2025)10.1038/s41467-025-56955-y

N/A

0DataRank · unranked

7 citations

Lianxin Hu, Liwei Jia, Jin Zhou, Tao Wang, Kangsan Kim +18 more

CD8+ T cells in the tumor microenvironment modulate the response to endocrine therapy in breast cancer

Journal of Clinical Investigation(2025)10.1172/jci188458

N/A

0DataRank · unranked

4 citations

Yunguan Wang, Dhivya R. Sudhan, Paula I. González-Ericsson, Luigi Formisano, Nisha Unni +26 more

BIT: Bayesian Identification of Transcriptional regulators from epigenomics-based query region sets

Nature Communications(2025)10.1038/s41467-025-60269-4

N/A

0DataRank · unranked

3 citations

Lin Xu, Xinlei Wang, Zeyu Lu

Blocking LAIR1 signaling in immune cells inhibits tumor development

Frontiers in Immunology(2022)10.3389/fimmu.2022.996026

N/A

0DataRank · unranked

32 citations

Xun Gui, Mi Deng, Heyu Chen, Yuanzhi Chen, Xiaoye Liu +15 more

Dimensionality reduction for visualizing spatially resolved profiling data using SpaSNE

GigaScience(2025)10.1093/gigascience/giaf002

N/A

0DataRank · unranked

3 citations

Chen Tang, Xue Xiao, Xiaowei Zhan, Tao Wang, Guanghua Xiao +2 more

A regularized Bayesian Dirichlet-multinomial regression model for integrating single-cell-level omics and patient-level clinical study data

Biometrics(2025)10.1093/biomtc/ujaf005

N/A

0DataRank · unranked

0 citations

Lei Yu, Lei Guo, Lin Xu, Qiwei Li, Yanghong Guo

Reprogramming lineage features promotes epithelial behavior in carcinoma cells

Cancer Letters(2025)10.1016/j.canlet.2025.218117

N/A

0DataRank · unranked

0 citations

Guosheng Fu, Chengxu Liao, Zhenyi Ma, Zhe Liu, Lin Xu +3 more

ARHGEF2 Isoform Switching Couples Intestinal Epithelial Barrier Function with Autophagic Response to Pathogens

Research Square(2025)10.21203/rs.3.rs-8252764/v1

N/A

0DataRank · unranked

0 citations

Shuyuan Chen, Alka Diwaker, Zhiheng Li, Abdulmajeed Salamah, Lei Guo +12 more

Targeting kinesin family member 20A sensitizes stem-like triple-negative breast cancer cells to standard chemotherapy

UNC Libraries(2025)10.17615/wy0f-mf84

N/A

0DataRank · unranked

0 citations

Yayoi Adachi, Jin Zhou, Wang, Tao, Cheng Zhang, Masashi Takeda +17 more

Engineering a serum response factor superactivator of smooth muscle gene expression with a condensate-forming domain

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2514363122

N/A

0DataRank · unranked

3 citations

Xinyi Zhou, Akansha M. Shah, Svetlana Bezprozvannaya, Kenian Chen, Qianqian Ding +5 more

Loss of function of the nuclear envelope protein LEMD2 causes DNA damage–dependent cardiomyopathy

Journal of Clinical Investigation(2022)10.1172/jci158897

N/A

0DataRank · unranked

23 citations

Andres Ramirez-Martinez, Peiheng Gan, Feng Wang, John McAnally, Lin Xu +4 more

Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention

Acta Pharmaceutica Sinica B(2022)10.1016/j.apsb.2022.02.020

N/A

0DataRank · unranked

11 citations

Na Li, Mingyang Huang, Xi Chen, Yu An, Jianping Li +13 more

Cross-Talk Between Histone Methyltransferases and Demethylases Regulate REST Transcription During Neurogenesis

Frontiers in Oncology(2022)10.3389/fonc.2022.855167

N/A

0DataRank · unranked

11 citations

Shinji Maegawa, Shavali Shaik, Ajay Sharma, Javiera Bravo‐Alegria, Lei Guo +4 more

Long-term maintenance of dystrophin expression and resistance to injury of skeletal muscle in gene edited DMD mice

Molecular Therapy — Nucleic Acids(2022)10.1016/j.omtn.2022.03.004

N/A

0DataRank · unranked

34 citations

Yu Zhang, Francesco Chemello, Yi-Li Min, Jian Huang, Jiwoong Kim +6 more

Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease

Science(2023)10.1126/science.ade1105

N/A

0DataRank · unranked

121 citations

Francesco Chemello, Xurde M. Caravia, Wei Tan, Hui Li, Kenian Chen +5 more

Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy

Science Translational Medicine(2022)10.1126/scitranslmed.ade1633

N/A

0DataRank · unranked

160 citations

Yu Zhang, Miao Cui, Hui Li, Efrain Sanchez‐Ortiz, John McAnally +7 more

Lin Xu

Indexed papers

Top data-sharing exemplar

Papers