Robert J. Lee

Hospital of the University of Pennsylvania

Also affiliated with University of Pennsylvania Health System, University of Pennsylvania

NursingNeuroscienceEngineeringMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “The ion channel CALHM6 controls bacterial infection‐induced cellular cross‐talk at the immunological synapse”.

The ion channel CALHM6 controls bacterial infection‐induced cellular cross‐talk at the immunological synapse

The EMBO Journal(2023)10.15252/embj.2022111450

N/A

0.854DataRank · unranked

25 citations

Zhongming Ma, Eirini Pantazi, Amrendra Kumar, Benjamin Demarco, Fabian A. Fischer +7 more

Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation

Nature Communications(2021)10.1038/s41467-020-20449-w

N/A

0.655DataRank · unranked

78 citations

Qinqin Fei, Vasudha Shukla, Hyunwook Lee, Pragi Patel, Rachel K. Putman +9 more

Impact of sweet, umami, and bitter taste receptor (TAS1R and TAS2R) genomic and expression alterations in solid tumors on survival

Scientific Reports(2022)10.1038/s41598-022-12788-z

N/A

0.500DataRank · unranked

27 citations

Tae‐Beom Kim, Noam A. Cohen, Robert J. Lee, Kevin T. Nead, Ryan M. Carey

HSP90 Modulates T2R Bitter Taste Receptor Nitric Oxide Production and Innate Immune Responses in Human Airway Epithelial Cells and Macrophages

Cells(2022)10.3390/cells11091478

N/A

0.483DataRank · unranked

24 citations

Benjamin M. Hariri, Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee, Ryan M. Carey

Interkingdom Detection of Bacterial Quorum-Sensing Molecules by Mammalian Taste Receptors

Microorganisms(2023)10.3390/microorganisms11051295

N/A

0.477DataRank · unranked

23 citations

Robert J. Lee, Yobouet Inès Kouakou

Small-molecule Akt-activation in airway cells induces NO production and reduces IL-8 transcription through Nrf-2

Respiratory Research(2021)10.1186/s12931-021-01865-y

N/A

0.434DataRank · unranked

17 citations

Li Eon Kuek, Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee, Indiwari Gopallawa

A deadly taste: linking bitter taste receptors and apoptosis

APOPTOSIS(2025)10.1007/s10495-025-02091-3

N/A

0.360DataRank · unranked

10 citations

Ryan M. Carey, Robert J. Lee, Zoey A. Miller

The bitter end: T2R bitter receptor agonists elevate nuclear calcium and induce apoptosis in non-ciliated airway epithelial cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.16.444376

N/A

0.279DataRank · unranked

5 citations

Li Eon Kuek, Madeline E. Johnson, Paige O. Johnson, Rachel L.J. Horn, Ryan M. Carey +4 more

Akt activator SC79 stimulates antibacterial nitric oxide generation in human nasal epithelial cells in vitro

International Forum of Allergy & Rhinology(2024)10.1002/alr.23318

N/A

0.208DataRank · unranked

3 citations

Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee

Quercetin as a Bitter Taste Receptor Agonist with Anticancer Effects in Head and Neck Cancer Cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.17.676947

N/A

0.104DataRank · unranked

1 citations

Sarah M. Sywanycz, B. Buchler, Robert D. Wardlow, Robert J. Lee, Ryan M. Carey +1 more

Savory Signaling: T1R umami receptor modulates endoplasmic reticulum calcium store content and release dynamics in airway epithelial cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.07.519477

N/A

0.104DataRank · unranked

1 citations

Jennifer F. Jolivert, Li Eon Kuek, Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee +1 more

Hops bitter β‐acids have antibacterial effects against sinonasal Staphylococcus aureus but also induce sinonasal cilia and mitochondrial dysfunction

International Forum of Allergy & Rhinology(2024)10.1002/alr.23487

N/A

0DataRank · unranked

4 citations

Joel C. Thompson, Li Tan, Zoey A. Miller, Ray Z., Nithin D. Adappa +4 more

Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer

Head & Neck(2025)10.1002/hed.28120

N/A

0DataRank · unranked

9 citations

Brianna L. Hill, Joel C. Thompson, Zoey A. Miller, Arielle Mueller, Robert J. Lee +2 more

Quercetin as a Bitter Taste Receptor Agonist with Anticancer Effects in Head and Neck Cancer Cells

Nutrients(2025)10.3390/nu17203224

N/A

0DataRank · unranked

2 citations

Sarah M. Sywanycz, B. Buchler, Robert D. Wardlow, Robert J. Lee, Ryan M. Carey +1 more

T2R5 agonist phendione decreases cell viability and induces apoptosis in head and neck squamous cell carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.14.654120

N/A

0DataRank · unranked

0 citations

Brianna L. Hill, Zoey A. Miller, Gavin Turner, Lily Huang, Kyle Polen +3 more

Altered polarization of PAR-2 signaling during airway epithelial remodeling

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.09.900555

N/A

0DataRank · unranked

0 citations

Jenna R. Freund, Benjamin M. Hariri, Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee +1 more

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy & Rhinology(2025)10.1002/alr.70084

N/A

0DataRank · unranked

0 citations

April Park, Yobouet Inès Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa +3 more

The bitter end: T2R bitter receptor agonists elevate nuclear calcium and induce apoptosis in non-ciliated airway epithelial cells

Cell Calcium(2021)10.1016/j.ceca.2021.102499

N/A

0DataRank · unranked

40 citations

Li Eon Kuek, Madeline E. Johnson, Paige O. Johnson, Rachel L.J. Horn, Ryan M. Carey +4 more

Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections

Pharmaceuticals(2022)10.3390/ph15040452

N/A

0DataRank · unranked

23 citations

Derek B. McMahon, Ray Ma, Zoey A. Miller, Jennifer F. Jolivert, Nithin D. Adappa +3 more

Microbial metabolite succinate activates solitary chemosensory cells in the human sinonasal epithelium

International Forum of Allergy & Rhinology(2022)10.1002/alr.23104

N/A

0DataRank · unranked

11 citations

Li Tan, Cailu Lin, John V. Bosso, Nithin D. Adappa, Robert J. Lee +4 more

Taste receptor T1R3 in nasal cilia detects Staphylococcus aureus D-amino acids to increase apical glucose uptake and enhance innate immunity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.21.512955

N/A

0DataRank · unranked

2 citations

Benjamin M. Hariri, Nithin D. Adappa, Nithin D. Adappa, Robert F. Margolskee, Noam A. Cohen +2 more

Bitter taste receptor-stimulated nitric oxide innate immune responses are reduced by loss of CFTR function in nasal epithelial cells and macrophages

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.21.508717

N/A

0DataRank · unranked

0 citations

Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee, Ryan M. Carey

Akt activator SC79 stimulates antibacterial nitric oxide production from human nasal epithelial cells and increases macrophage phagocytosis in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.31.514559

N/A

0DataRank · unranked

0 citations

Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee

Savory Signaling: T1R Umami Receptor Modulates Endoplasmic Reticulum Calcium Store Content and Release Dynamics in Airway Epithelial Cells

Nutrients(2023)10.3390/nu15030493

N/A

0DataRank · unranked

8 citations

Jennifer F. Jolivert, Li Eon Kuek, Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee +1 more

Data from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses

(2023)10.1158/0008-5472.c.6496785

N/A

0DataRank · unranked

0 citations

Nina Dmitrieva, Davide Gianni, Elisabeth J. Fontana, Xiaogang Pan, Yanhui Lu +13 more

Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer’s disease

Brain Behavior and Immunity(2024)10.1016/j.bbi.2024.05.006

N/A

0DataRank · unranked

29 citations

Kylene P. Daily, Mostafa Eltobgy, Shady Estfanous, Michelle H. Tan, Jimmy Chun‐Tien Kuo +19 more

Effects of Akt Activator SC79 on Human M0 Macrophage Phagocytosis and Cytokine Production

Cells(2024)10.3390/cells13110902

N/A

0DataRank · unranked

6 citations

Nithin D. Adappa, Nithin D. Adappa, Robert J. Lee