Ajit G. Thomas

Also affiliated with Johns Hopkins Medicine

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 17 papers. Top paper: “Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease”.

Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00278

N/A

0.581DataRank · unranked

47 citations

Kristen R. Hollinger, Ajit G. Thomas, Ranjeet Prasad Dash, Carolyn Tallon, Vijayabhaskar Veeravalli +12 more

Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome

Theranostics(2020)10.7150/thno.41714

N/A

0.505DataRank · unranked

28 citations

Anjali Sharma, Rajasekhar R. Ramireddy, Ajit G. Thomas, Jesse Alt, Amanda Fowler +7 more

A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis

Science Translational Medicine(2023)10.1126/scitranslmed.abn7491

N/A

0.434DataRank · unranked

17 citations

Lauren Norris, Lukáš Tenora, Ivan Šnajdr, András K. Ponti, Xiaolei Zhu +10 more

Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115698

N/A

0.416DataRank · unranked

15 citations

Sarah C. Zimmermann, Run-Duo Gao, Ajit G. Thomas, Filip Kalčic, Vijayabhaskar Veeravalli +7 more

Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115674

N/A

0.208DataRank · unranked

3 citations

Ajit G. Thomas, Ondřej Štěpánek, Brennan A. Murphy, Niyada Hin, Jan Skácel +10 more

Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00759

N/A

0.208DataRank · unranked

3 citations

Yannan Li, Ajit G. Thomas, A. Sharma, Wathsala Liyanage, Tomáš Tichý +13 more

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model

Translational Neurodegeneration(2023)10.1186/s40035-023-00383-9

N/A

0DataRank · unranked

24 citations

Benjamin J. Bell, Medhinee M. Malvankar, Pragney Deme, Carlos Nogueras‐Ortiz, Erden Eren +12 more

T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade

JCI Insight(2023)10.1172/jci.insight.160345

N/A

0DataRank · unranked

23 citations

Elizabeth A. Thompson, Sepideh Gharaie, Chirag H. Patel, Johanna T. Kurzhagen, Phillip M. Pierorazio +6 more

Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity and improves motor function in a rabbit model of cerebral palsy

Journal of Controlled Release(2023)10.1016/j.jconrel.2023.04.017

N/A

0DataRank · unranked

16 citations

Zhi Zhang, Jesse Alt, Siva P. Kambhampati, Anjali Sharma, Sarabdeep Singh +8 more

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer’s disease

Research Square(2023)10.21203/rs.3.rs-3131295/v1

N/A

0DataRank · unranked

4 citations

Benjamin J. Bell, Medhinee M. Malvankar, Pragney Deme, Carlos Nogueras‐Ortiz, Erden Eren +12 more

GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice

International Journal of Molecular Sciences(2024)10.3390/ijms25136893

N/A

0DataRank · unranked

5 citations

Meixiang Huang, Ajit G. Thomas, John Maragakis, Kaitlyn Huizar, Yuxin Zheng +4 more

Mass spectrometry-guided discovery of novel GCPII inhibitor scaffolds

Frontiers in Pharmacology(2025)10.3389/fphar.2025.1646207

N/A

0DataRank · unranked

0 citations

Ajit G. Thomas, John Janiszewski, Nate Hoxie, Chae Bin Lee, Ying Wu +13 more

Inhibition of neutral sphingomyelinase 2 promotes remyelination

Science Advances(2020)10.1126/sciadv.aba5210

N/A

0DataRank · unranked

37 citations

Amit Agarwal, Matthew D. Smith, Saja S. Khuder, Emily G. Baxi, Ajit G. Thomas +7 more

Microglia-targeted dendrimer-2PMPA therapy robustly inhibits GCPII and improves cognition in a mouse model of multiple sclerosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.22.055228

N/A

0DataRank · unranked

1 citations

Anjali Sharma, Carolyn Tallon, Lyndah Lovell, Ajit G. Thomas, Xiaolei Zhu +9 more

Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis

Nanotheranostics(2021)10.7150/ntno.63158

N/A

0DataRank · unranked

47 citations

Anjali Sharma, Carolyn Tallon, Lyndah Lovell, Ajit G. Thomas, Xiaolei Zhu +11 more

Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury

Biochemical Pharmacology(2021)10.1016/j.bcp.2021.114796

N/A

0DataRank · unranked

42 citations

Silvia Picciolini, Seung‐Wan Yoo, Ajit G. Thomas, Arindom Pal, Jesse Alt +7 more

Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice

Pharmaceutics(2022)10.3390/pharmaceutics14102066

N/A

0DataRank · unranked

27 citations

Benjamin J. Bell, Anjali Sharma, Arindom Pal, Medhinee M. Malvankar, Ajit G. Thomas +10 more