Sean F. Brady

MedicineBiochemistry, Genetics and Molecular BiologyEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance”.

Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance

Science(2022)10.1126/science.abn4213

N/A

4.1DataRank · unranked

123 citations

Bimal Koirala, Yözen Hernández, Matthew Zimmerman, Sean F. Brady, Zongqiang Wang

A naturally inspired antibiotic to target multidrug-resistant pathogens

Nature(2022)10.1038/s41586-021-04264-x

N/A

0.818DataRank · unranked

233 citations

Bimal Koirala, Yözen Hernández, Matthew Zimmerman, Steven Park, David S. Perlin +2 more

Total Synthesis of Malacidin A by β‐Hydroxyaspartic Acid Ligation‐Mediated Cyclization and Absolute Structure Establishment

Angewandte Chemie International Edition(2020)10.1002/anie.202009092

N/A

0.533DataRank · unranked

34 citations

Zhuo Shang, Nicholas Forelli, Kathy Hiu Laam Po, Sheng Chen, Sean F. Brady +2 more

Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis

Nature Communications(2022)10.1038/s41467-022-28292-x

N/A

0.494DataRank · unranked

26 citations

Nicholas Forelli, Yözen Hernández, Melinda A. Ternei, Sean F. Brady, Zongqiang Wang

Discovery of Paenibacillaceae Family Gram-Negative-Active Cationic Lipopeptide Antibiotics Using Evolution-Guided Chemical Synthesis

Organic Letters(2022)10.1021/acs.orglett.2c01879

N/A

0.425DataRank · unranked

16 citations

Bimal Koirala, Yözen Hernández, Sean F. Brady, Zongqiang Wang

Unraveling function and diversity of bacterial lectins in the human microbiome

Nature Communications(2022)10.1038/s41467-022-29949-3

N/A

0.396DataRank · unranked

13 citations

Sun M. Han, Pearson Lau, Daniela Guisado, Yupu Liang, Toshiki G. Nakashige +5 more

Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn‐BNP)‐Coupled Metagenomics

Angewandte Chemie International Edition(2024)10.1002/anie.202317187

N/A

0.265DataRank · unranked

4 citations

Amanda C. Kasper, Mai Takahashi, Adrian Morales Amador, Abir Bhattacharjee, Jingbo Kan +4 more

High-throughput retrieval of target sequences from complex clone libraries using CRISPRi

Nature Biotechnology(2022)10.1038/s41587-022-01531-8

N/A

0DataRank · unranked

9 citations

Vincent Libis, Yözen Hernández, Liliana Guerrero-Porras, Melinda A. Ternei, Sean F. Brady +1 more

Bacterial cGAS senses a viral RNA to initiate immunity

Nature(2023)10.1038/s41586-023-06743-9

N/A

0DataRank · unranked

62 citations

Cameron G. Roberts, Adrián Morales-Amador, Brandon A. Berryhill, Waqas Chaudhry, Bruce R. Levin +3 more

Present and future outlooks on environmental DNA-based methods for antibiotic discovery

Current Opinion in Microbiology(2023)10.1016/j.mib.2023.102335

N/A

0DataRank · unranked

7 citations

Ján Burian, Sean F. Brady, Adam Rosenzweig

Bacterial cGAS senses a viral RNA to initiate immunity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.07.531596

N/A

0DataRank · unranked

13 citations

Cameron G. Roberts, Adrian Morales Amador, Sean F. Brady, Luciano A. Marraffini, Dalton V. Banh

Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma

Nature(2024)10.1038/s41586-024-08224-z

N/A

0DataRank · unranked

30 citations

Swathi V. Iyer, David Chun-Cheng Hsieh, Buren Li, Harold K. Elias, Tao Wang +11 more

DNA glycosylases provide antiviral defence in prokaryotes

Nature(2024)10.1038/s41586-024-07329-9

N/A

0DataRank · unranked

26 citations

Ying Z. Pigli, Christian F. Baca, Søren Heissel, Alexis Thomas, Vincent Libis +6 more

Identification of an Optimized Clinical Development Candidate from Cilagicin, an Antibiotic That Evades Resistance by Dual Polyprenyl Phosphate Binding

ACS Infectious Diseases(2024)10.1021/acsinfecdis.4c00018

N/A

0DataRank · unranked

5 citations

Kaylyn Spotton, Abir Bhattacharjee, Adrián Morales-Amador, Sean F. Brady, Adam Rosenzweig

Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn‐BNP)‐Coupled Metagenomics

Angewandte Chemie(2024)10.1002/ange.202317187

N/A

0DataRank · unranked

1 citations

Amanda C. Kasper, Mai Takahashi, Adrian Morales Amador, Abir Bhattacharjee, Jingbo Kan +4 more

Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.27.596031

N/A

0DataRank · unranked

1 citations

Adrian Morales, Yözen Hernández, Melinda A. Ternei, Christophe Lemetre, Logan W Maclntyre +3 more

Bioactive molecules unearthed by terabase-scale long-read sequencing of a soil metagenome

Nature Biotechnology(2025)10.1038/s41587-025-02810-w

N/A

0DataRank · unranked

8 citations

Robert E. Boer, Yözen Hernández, Adrián Morales-Amador, Linhai Jiang, Abir Bhattacharjee +4 more

A Semisynthetic Kanglemycin Shows In Vivo Efficacy against High-Burden Rifampicin Resistant Pathogens

ACS Infectious Diseases(2020)10.1021/acsinfecdis.0c00223

N/A

0DataRank · unranked

18 citations

Jiayi Xu, Han Wang, Shraddha Suryavanshi, Matthew Zimmerman, Riccardo Russo +4 more

Environmental resistome–guided development of resistance-tolerant antibiotics

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2504781122

N/A

0DataRank · unranked

3 citations

Abir Bhattacharjee, Ján Burian, David Chun-Cheng Hsieh, Yözen Hernández, Melinda A. Ternei +3 more

Total Synthesis of Malacidin A by β‐Hydroxyaspartic Acid Ligation‐Mediated Cyclization and Absolute Structure Establishment

Angewandte Chemie(2020)10.1002/ange.202009092

N/A

0DataRank · unranked

4 citations

Zhuo Shang, Nicholas Forelli, Kathy Hiu Laam Po, Sheng Chen, Sean F. Brady +2 more

Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals

mSphere(2021)10.1128/msphere.00711-21

N/A

0DataRank · unranked

29 citations

Hans-Heinrich Hoffmann, Young Joo Choi, Gabriel I. Small, Alison W. Ashbrook, Bimal Koirala +5 more

Metagenome‐Guided Analogue Synthesis Yields Improved Gram‐Negative‐Active Albicidin‐ and Cystobactamid‐Type Antibiotics

Angewandte Chemie International Edition(2021)10.1002/anie.202104874

N/A

0DataRank · unranked

20 citations

Amanda C. Kasper, Rabia Mehmood, Melinda A. Ternei, Shaogang Li, Joel S. Freundlich +2 more

Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.128484

N/A

0DataRank · unranked

10 citations

Bimal Koirala, Sean F. Brady, James Peek

Multiplexed functional metagenomic analysis of the infant microbiome identifies effectors of NF-κB, autophagy, and cellular redox state

Cell Reports(2021)10.1016/j.celrep.2021.109746

N/A

0DataRank · unranked

7 citations

Shawn T. Whitfield, Toshiki G. Nakashige, Andréia Bergamo Estrela, Thahmina Ali, Sean F. Brady +1 more

Multiplexed mobilization and expression of biosynthetic gene clusters

Nature Communications(2022)10.1038/s41467-022-32858-0

N/A

0DataRank · unranked

40 citations

Logan W. MacIntyre, Rabia Mehmood, Liliana Guerrero, Melinda A. Ternei, Niv Antonovsky +4 more