Timothy L. Frankel

Also affiliated with Michigan Medicine, Ann Arbor Center for Independent Living

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Data from Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

(2023)10.1158/2159-8290.c.6651113.v1

Top 100%

0DataRank

Top 100%0 citations

Ahmed M. Elhossiny, Padma Kadiyala, Jay Li, Jake McGue, Brian D. Griffith +25 more

Papers

Driven by 41 papers — median percentile 0. Top paper: “Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma”.

Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma

Cancers(2020)10.3390/cancers12123816

N/A

0.701DataRank · unranked

106 citations

Jayati Chakrabarti, Joanne Lundy, Daniel Croagh, Pritha Adhikary, Scott S. Richards +13 more

KRASG12D drives immunosuppression in lung adenocarcinoma through paracrine signaling

JCI Insight(2025)10.1172/jci.insight.182228

N/A

0.491DataRank · unranked

13 citations

Ivana Barravecchia, Elyse McLintock, Jennifer M. Lee, Sarah F. Ferris, Carlos E. Espinoza +12 more

Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms Reveals Divergent Indolent and Malignant States

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-24-1529

N/A

0.345DataRank · unranked

9 citations

Ashley A. Fletcher, Jude Ogechukwu Okoye, Chanjuan Shi, Fengming Chen, Elishama Kanu +8 more

Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.25.493422

N/A

0.345DataRank · unranked

9 citations

Amanda K. Huber, Rashi Singhal, Ryan J. Rebernick, Roshan Kumar, Nupur K. Das +17 more

Analysis of donor pancreata defines the transcriptomic signature and microenvironment of early pre-neoplastic pancreatic lesions

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.13.523300

N/A

0.208DataRank · unranked

3 citations

Ahmed M. Elhossiny, Padma Kadiyala, Jay Li, Jake McGue, Brian D. Griffith +24 more

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer

Cell Metabolism(2022)10.1016/j.cmet.2022.11.013

N/A

0DataRank · unranked

176 citations

Amanda K. Huber, Rashi Singhal, Navyateja Korimerla, Ryan J. Rebernick, Roshan Kumar +21 more

Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.02.016

N/A

0DataRank · unranked

90 citations

Katelyn L. Donahue, Kristee L. Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar +22 more

Cellular engagement and interaction in the tumor microenvironment predict non-response to PD-1/PD-L1 inhibitors in metastatic non-small cell lung cancer

Scientific Reports(2022)10.1038/s41598-022-13236-8

N/A

0DataRank · unranked

15 citations

Fatima Lima, Samantha L. Bell, Gregory P. Kalemkerian, Bryan J. Schneider, Nithya Ramnath +6 more

MHC Class II Expression Influences the Composition and Distribution of Immune Cells in the Metastatic Colorectal Cancer Microenvironment

Cancers(2022)10.3390/cancers14174092

N/A

0DataRank · unranked

15 citations

Simon Turcotte, Jenny Lazarus, Fátima Lima, Samantha L. Bell, Lawrence Delrosario +11 more

GaWRDenMap: a quantitative framework to study the local variation in cell–cell interactions in pancreatic disease subtypes

Scientific Reports(2022)10.1038/s41598-022-06602-z

N/A

0DataRank · unranked

8 citations

Shariq Mohammed, Timothy L. Frankel, Arvind Rao, Santhoshi Krishnan

Towards the characterization of the tumor microenvironment through dictionary learning-based interpretable classification of multiplexed immunofluorescence images

Physics in Medicine and Biology(2022)10.1088/1361-6560/aca86a

N/A

0DataRank · unranked

2 citations

Souptik Barua, Timothy L. Frankel, Arvind Rao, Santhoshi Krishnan

Multiplex Immunohistochemistry and Immunofluorescence: A Practical Update for Pathologists

Modern Pathology(2023)10.1016/j.modpat.2023.100197

N/A

0DataRank · unranked

174 citations

Timothy L. Frankel, Myrto Moutafi, Arvind Rao, David L. Rimm, Janis M. Taube +4 more

Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

Cancer Cell(2023)10.1016/j.ccell.2022.12.008

N/A

0DataRank · unranked

151 citations

Jae Eun Choi, Ilona Kryczek, Yilun Sun, Peng Liao, Shasha Li +22 more

Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

Cancer Discovery(2023)10.1158/2159-8290.cd-23-0013

N/A

0DataRank · unranked

144 citations

Ahmed M. Elhossiny, Padma Kadiyala, Jay Li, Jake McGue, Brian D. Griffith +25 more

Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression

iScience(2023)10.1016/j.isci.2023.107408

N/A

0DataRank · unranked

36 citations

Srija Chakraborty, Lena Bercz, Liliana D’Alesio, Jessica Wedig, Molly Torok +14 more

KRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-1421

N/A

0DataRank · unranked

31 citations

Padma Kadiyala, Ahmed M. Elhossiny, Samantha B. Kemp, Jay Li, Nina G. Steele +41 more

Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice

Molecular Cancer Research(2023)10.1158/1541-7786.mcr-23-0480

N/A

0DataRank · unranked

10 citations

Jennifer M. Lee, Jason Manassa, Brian Magnuson, Sarah F. Ferris, Sophia Cavanaugh +8 more

Unique characteristics of the tumor immune microenvironment in young patients with metastatic colorectal cancer

Frontiers in Immunology(2023)10.3389/fimmu.2023.1289402

N/A

0DataRank · unranked

10 citations

Jenny Lazarus, Jake McGue, Santhoshi Krishnan, Michael I. D’Angelica, Jinru Shia +6 more

Data from Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

(2023)10.1158/2159-8290.c.6651113.v1

Top 100%

0DataRank

Top 100%0 citations

Ahmed M. Elhossiny, Padma Kadiyala, Jay Li, Jake McGue, Brian D. Griffith +25 more

Data from Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

(2023)10.1158/2159-8290.c.6651113.v2

Top 100%

0DataRank

Top 100%0 citations

Ahmed M. Elhossiny, Padma Kadiyala, Jay Li, Jake McGue, Brian D. Griffith +25 more

Clinicogenomic analysis of rare histologic variants of pancreatic carcinoma: Undifferentiated carcinomas with and without osteoclast-like giant cells.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.e16001

N/A

0DataRank · unranked

0 citations

Valerie Gunchick, Jiaqi Shi, Aaron M. Udager, Timothy L. Frankel, Vaibhav Sahai +2 more

Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.20.545616

N/A

0DataRank · unranked

0 citations

Jennifer M. Lee, Jason Manassa, Brian Magnuson, Sophia Cavanaugh, Nina G. Steele +7 more

The Aryl Hydrocarbon Receptor: Impact on the Tumor Immune Microenvironment and Modulation as a Potential Therapy

Cancers(2024)10.3390/cancers16030472

N/A

0DataRank · unranked

30 citations

Timothy L. Frankel, Brian D. Griffith

SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma

JCI Insight(2024)10.1172/jci.insight.184826

N/A

0DataRank · unranked

16 citations

Marwa O. El-Derany, Jadyn G. James, Zhuwen Wang, Ashley N. Pearson, Erin A. Holcomb +26 more

A Comparison of Spatial and Phenotypic Immune Profiles of Pancreatic Ductal Adenocarcinoma and Its Precursor Lesions

International Journal of Molecular Sciences(2024)10.3390/ijms25052953

N/A

0DataRank · unranked

15 citations

Jiaqi Shi, Jake McGue, Brian D. Griffith, Lei Sun, Vaibhav Sahai +3 more

CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival

Cancer Immunology Immunotherapy(2024)10.1007/s00262-024-03678-6

N/A

0DataRank · unranked

7 citations

Shrina Jasani, Debasmita Mukherjee, Hannah Lathrop, Priya Matreja, Timothy Pfau +16 more

Proximogram—A multi-omics network-based framework to capture tissue heterogeneity integrating single-cell omics and spatial profiling

Computers in Biology and Medicine(2024)10.1016/j.compbiomed.2024.109082

N/A

0DataRank · unranked

6 citations

Sunjong Ji, Ahmed M. Elhossiny, Achyutha Rao, Timothy L. Frankel, Arvind Rao +1 more

Development of a Multiplex Immunofluorescence Assay for Tumor Microenvironment Studies of Human and Murine Merkel Cell Carcinoma

Laboratory Investigation(2024)10.1016/j.labinv.2024.102128

N/A

0DataRank · unranked

5 citations

Monique Verhaegen, Jake McGue, Alberto C. Olivei, Andrzej A. Dlugosz, Timothy L. Frankel +2 more

Assessing the Tumor Immune Landscape Across Multiple Spatial Scales to Differentiate Immunotherapy Response in Metastatic Non-Small Cell Lung Cancer

Laboratory Investigation(2024)10.1016/j.labinv.2024.102148

N/A

0DataRank · unranked

4 citations

Santhoshi Krishnan, Joel Eliason, Jake J. McGue, Angel Qin, Timothy L. Frankel +2 more

Characterization of undifferentiated carcinomas of the pancreas with and without osteoclast-like giant cells

JNCI Cancer Spectrum(2024)10.1093/jncics/pkae097

N/A

0DataRank · unranked

2 citations

Valerie Gunchick, Jake McGue, Zhaoping Qin, Chandan Kumar‐Sinha, Filip Bednar +7 more

Primary and metastatic cellular landscapes in human pancreatic cancer

iScience(2025)10.1016/j.isci.2025.113012

N/A

0DataRank · unranked

6 citations

Veerin R. Sirihorachai, Ahmed M. Elhossiny, Ian M. Loveless, Padma Kadiyala, Monica E. Bonilla +16 more

IL-22BP Modulates Injury in Acute Pancreatitis but Delays Tissue Recovery in Chronic Pancreatitis

Cellular and Molecular Gastroenterology and Hepatology(2025)10.1016/j.jcmgh.2025.101520

N/A

0DataRank · unranked

4 citations

A Spiteri, Brian D. Griffith, Yaqing Zhang, Marina Pasca di Magliano, Alberto C. Olivei +4 more

Immunocompetent Murine Models Recapitulate the Heterogeneous Tumor-Immune Microenvironment of Human Liposarcoma

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-25-1628

N/A

0DataRank · unranked

1 citations

Emma Kenna, Lexi-Ann F. Golden, Ahmed M. Elhossiny, Kyle D. Perry, Jodi Wilkowski +16 more

Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0377

N/A

0DataRank · unranked

1 citations

Padma Kadiyala, Jake McGue, Lei Sun, Aadith Kumar, Carlos E. Espinoza +16 more

EGFR activation in cholangiocytes promotes extrahepatic bile duct regeneration after injury

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.22.649788

N/A

0DataRank · unranked

2 citations

Takuki Sakaguchi, Mirabelle Peter, John W. Tobias, Timothy L. Frankel, Nataliya Razumilava +1 more

Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer

Nature Cancer(2020)10.1038/s43018-020-00121-4

N/A

0DataRank · unranked

584 citations

Eileen S. Carpenter, Samantha B. Kemp, Veerin R. Sirihorachai, Stephanie The, Lawrence Delrosario +34 more

Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.31.634916

N/A

0DataRank · unranked

0 citations

Emma Kenna, Lexi-Ann F. Golden, Ahmed M. Elhossiny, Kyle Perry, Jodi Wilkowski +16 more

Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-3715

N/A

0DataRank · unranked

281 citations

Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard, Li-Jyun Syu +31 more

IFNγ signaling integrity in colorectal cancer immunity and immunotherapy

Cellular and Molecular Immunology(2021)10.1038/s41423-021-00735-3

N/A

0DataRank · unranked

144 citations

Timothy L. Frankel, Michael Green, Weiping Zou, Wan Du

Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages

Life Science Alliance(2021)10.26508/lsa.202000935

N/A

0DataRank · unranked

142 citations

Nina G. Steele, Eileen S. Carpenter, Katelyn L. Donahue, Grace G. Bushnell, Aaron H. Morris +19 more

Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.26.457660

N/A

0DataRank · unranked

3 citations

Katelyn L. Donahue, Kristee Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar +18 more

Timothy L. Frankel

Indexed papers

Top data-sharing exemplar

Papers