Xuan Zhang

Also affiliated with Jiangsu University of Science and Technology, Green Chemistry

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity”.

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Nature Communications(2020)10.1038/s41467-020-15838-0

N/A

0.838DataRank · unranked

266 citations

Xuan Zhang, Jianhui Chang, Ha‐Neui Kim, Peiyi Zhang, Yingying Wang +17 more

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Journal of Hematology & Oncology(2020)10.1186/s13045-020-00928-9

N/A

0.739DataRank · unranked

137 citations

Raphael Koch, Vivekananda Budamagunta, Peiyi Zhang, Xuan Zhang, Sajid Khan +11 more

Rosetta’s Predictive Ability for Low-Affinity Ligand Binding in Fragment-Based Drug Discovery

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.18.512794

N/A

0.104DataRank · unranked

1 citations

Shannon T. Smith, Brian J. Bender, Brittany Allison, Soumya Ganguly, Alexander R. Geanes +4 more

Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112186

N/A

0DataRank · unranked

115 citations

Dinesh Thummuri, Xingui Liu, Wanyi Hu, Peiyi Zhang, Sajid Khan +4 more

Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation

Cell(2020)10.1016/j.cell.2020.02.020

N/A

0DataRank · unranked

106 citations

Do‐Hwan Lim, Wubin Ma, Brandon E. Aubol, Yajing Hao, Xin Wang +15 more

Discovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112397

N/A

0DataRank · unranked

65 citations

Yonghan He, Peiyi Zhang, Vivekananda Budamagunta, Dongwen Lv, Dinesh Thummuri +6 more

Deuteration of the farnesyl terminal methyl groups of δ-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115498

N/A

0DataRank · unranked

8 citations

Zhengya Gao, Qiang Fu, Lin Song, Peiyi Zhang, Xuan Zhang +5 more

PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

Exploration of Targeted Anti-tumor Therapy(2020)10.37349/etat.2020.00017

N/A

0DataRank · unranked

23 citations

Xuan Zhang, Xingui Liu, Sajid Khan, Daohong Zhou, Guangrong Zheng +1 more

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Nature Communications(2021)10.1038/s41467-021-27210-x

N/A

0DataRank · unranked

149 citations

Pratik Pal, Xingui Liu, Yannan Jia, Dinesh Thummuri, Peiyi Zhang +19 more

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-21-0474

N/A

0DataRank · unranked

74 citations

Sajid Khan, Patrick W. Underwood, Peiyi Zhang, J Wiegand, Xuan Zhang +13 more

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells

Nature Communications(2021)10.1038/s41467-021-21573-x

N/A

0DataRank · unranked

55 citations

Umasankar De, Sajid Khan, Yuewan Luo, Myung‐Chul Kim, Haijun Yu +14 more

Concise Synthesis of (S)-δ-CEHC, a Metabolite of Vitamin E

ACS Omega(2021)10.1021/acsomega.0c05658

N/A

0DataRank · unranked

4 citations

Pratik Pal, Peiyi Zhang, Xuan Zhang, Guangrong Zheng, Matthew Burke

Piperlongumine (PL) conjugates induce targeted protein degradation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.21.474712

N/A

0DataRank · unranked

6 citations

Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Yaxia Yuan +12 more

Co-targeting BCL-X L and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.12.507616

N/A

0DataRank · unranked

0 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Piperlongumine conjugates induce targeted protein degradation

Cell chemical biology(2023)10.1016/j.chembiol.2023.01.004

N/A

0DataRank · unranked

71 citations

Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Yaxia Yuan +12 more

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell Death Discovery(2023)10.1038/s41420-022-01296-8

N/A

0DataRank · unranked

43 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation

Cell chemical biology(2023)10.1016/j.chembiol.2023.07.010

N/A

0DataRank · unranked

43 citations

Seth Hale, Nikee Awasthee, Chengcheng Meng, Xuan Zhang, Yi Liu +8 more

Design and optimization of piperlongumine analogs as potent senolytics

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129593

N/A

0DataRank · unranked

4 citations

Yonghan He, Xingui Liu, Xin Zhang, Peizhong Shi, Yingying Wang +3 more

Discovery of XZ338, a highly potent BCL-XL degrader

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117624

N/A

0DataRank · unranked

5 citations

Dinesh Thummuri, Wanyi Hu, Xingui Liu, Peiyi Zhang, Shuo Zhou +3 more

Discovery of PZ671, a highly potent and in vivo active CRBN-recruiting Bcl-xL degrader

RSC Medicinal Chemistry(2025)10.1039/d5md00119f

N/A

0DataRank · unranked

3 citations

Dinesh Thummuri, Wanyi Hu, Sajid Khan, Yonghan He, Xuan Zhang +5 more

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

Journal of Hematology & Oncology(2020)10.1186/s13045-020-00924-z

N/A

0DataRank · unranked

123 citations

Sajid Khan, Zhiguang Huo, Dongwen Lv, Xuan Zhang, Xingui Liu +6 more

Discovery of histone deacetylase 3 (HDAC3)-specific PROTACs

Chemical Communications(2020)10.1039/d0cc03243c

N/A

0DataRank · unranked

120 citations

Wei Jia, Lisa Zhao, Xinyi Chen, Guangrong Zheng, Xuan Zhang +2 more