Albert R. La Spada

Also affiliated with University of California System

NeuroscienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.380Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics

Neuron(2025)10.1016/j.neuron.2025.05.014

Top 48%

0.380DataRank

Top 48%9 citations

Ricardo Miramontes, Jie Wu, Ravinder Gulia, Madhu Sudhana Saddala, Alice Lau +7 more

Papers

Driven by 37 papers — median percentile 52. Top paper: “Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders”.

Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders

Nature Communications(2023)10.1038/s41467-023-36311-8

N/A

1.2DataRank · unranked

57 citations

Frederick J. Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels +4 more

Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics

Neuron(2025)10.1016/j.neuron.2025.05.014

Top 48%

0.380DataRank

Top 48%9 citations

Ricardo Miramontes, Jie Wu, Ravinder Gulia, Madhu Sudhana Saddala, Alice Lau +7 more

Harmony Lost: Cell–Cell Communication at the Neuromuscular Junction in Motor Neuron Disease

Trends in Neurosciences(2020)10.1016/j.tins.2020.07.002

N/A

0DataRank · unranked

29 citations

Albert R. La Spada, Anastasia Gromova

Tight expression regulation of senataxin, linked to motor neuron disease and ataxia, is required to avert cell-cycle block and nucleolus disassembly

Heliyon(2020)10.1016/j.heliyon.2020.e04165

N/A

0DataRank · unranked

14 citations

Bryce L. Sopher, Albert R. La Spada, Craig L. Bennett

Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice

Disease Models & Mechanisms(2020)10.1242/dmm.042424

N/A

0DataRank · unranked

13 citations

Leonette Victoria Naakuma Delali Annan, James R. Dick, Albert R. La Spada, Michael G. Hanna, Linda Greensmith +2 more

In vivo assessment of neurodegeneration in Spinocerebellar Ataxia type 7

medRxiv(2020)10.1101/2020.10.05.20207340

N/A

0DataRank · unranked

0 citations

Shabbir Hussain I. Merchant, Sanaz Attaripour-Isfahani, Hyun Joo Cho, Patrick Mcgurrin, Brian P. Brooks +5 more

SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease

Molecular Genetics & Genomic Medicine(2021)10.1002/mgg3.1745

N/A

0DataRank · unranked

27 citations

Albert R. La Spada, Craig L. Bennett

Respiratory dysfunction in a mouse model of spinocerebellar ataxia type 7

Disease Models & Mechanisms(2021)10.1242/dmm.048893

N/A

0DataRank · unranked

21 citations

Logan A. Pucci, Paweł M. Świtoński, Debolina D. Biswas, Angela L. McCall, Amanda F. Kahn +5 more

Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7

Cell Reports(2021)10.1016/j.celrep.2021.110062

N/A

0DataRank · unranked

20 citations

Joe R. Delaney, Luke C. Bartelt, Chenchen Niu, María Ramos Zapatero, Nathanael J. Spann +7 more

De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01277-5

N/A

0DataRank · unranked

15 citations

Kathie J. Ngo, Daniel Y. Conway, John Provias, Steven K. Baker, Lauren Brady +5 more

In vivo assessment of neurodegeneration in Spinocerebellar Ataxia type 7

NeuroImage Clinical(2021)10.1016/j.nicl.2021.102561

N/A

0DataRank · unranked

6 citations

Shabbir Hussain I. Merchant, Sanaz Attaripour-Isfahani, Hyun Joo Cho, Patrick Mcgurrin, Brian P. Brooks +5 more

Clonally expanded CD8 T cells characterize Amyotrophic Lateral Sclerosis 4

Research Square(2021)10.21203/rs.3.rs-798338/v1

N/A

0DataRank · unranked

1 citations

Laura Campisi, Shahab Chizari, Anastasia Gromova, Frederick J. Arnold, Lorena Mosca +13 more

Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4

Nature(2022)10.1038/s41586-022-04844-5

N/A

0DataRank · unranked

92 citations

Shahab Chizari, Jessica Ho, Anastasia Gromova, Frederick J. Arnold, Lorena Mosca +21 more

Skeletal Muscle TFEB Signaling Promotes Central Nervous System Function and Reduces Neuroinflammation during Aging and Neurodegenerative Disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.07.482891

N/A

0DataRank · unranked

9 citations

Allison Birnbaum, Anastasia Gromova, Amy Huang, Kailin Liu, Eleanor A. Liu +16 more

Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease

Cell Reports(2023)10.1016/j.celrep.2023.113436

N/A

0DataRank · unranked

36 citations

Allison Birnbaum, Anastasia Gromova, Amy Huang, Kailin Liu, Eleanor A. Liu +16 more

Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability

Cell(2023)10.1016/j.cell.2023.09.008

N/A

0DataRank · unranked

27 citations

Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit Laxmikant Deshmukh +34 more

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function

Science Advances(2023)10.1126/sciadv.ade1694

N/A

0DataRank · unranked

12 citations

Laura Tosatto, Emanuela Zuccaro, Eric N. Anderson, Antonella Falconieri, María José Polanco +17 more

MAP4K3 inhibits Sirtuin-1 to repress the LKB1–AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex

Life Science Alliance(2023)10.26508/lsa.202201525

N/A

0DataRank · unranked

4 citations

Cynthia L. Hsu, Kohta Ohnishi, Wen-Chuan Shen, Elian Lee, Jill Meisenhelder +6 more

Protocol for mapping double-stranded DNA break sites across the genome with translocation capture sequencing

STAR Protocols(2023)10.1016/j.xpro.2023.102205

N/A

0DataRank · unranked

1 citations

Albert R. La Spada, Joe R. Delaney

PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.09.536178

N/A

0DataRank · unranked

2 citations

Ryan Baumert, Gabrielle Séjourné, Dhanesh Sivadasan Bindu, Kylie Dimond, Kristina Sakers +12 more

Respiratory neuropathology in spinocerebellar ataxia type 7

JCI Insight(2024)10.1172/jci.insight.170444

N/A

0DataRank · unranked

3 citations

Yihan Shi, Léa El Haddad, Ronit Sethi, Meredith Huston, Sean Kehoe +8 more

Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue

Cell Reports Methods(2024)10.1016/j.crmeth.2024.100816

N/A

0DataRank · unranked

2 citations

Mouad Fakhri, Grażyna Adamek, Magdalena Trybus, Anna Samelak-Czajka, Paulina Jackowiak +5 more

Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7

Frontiers in Molecular Neuroscience(2024)10.3389/fnmol.2024.1478110

N/A

0DataRank · unranked

1 citations

Maile Adams, Julien Philippe, Albert R. La Spada, Joshua G. Macopson-Jones

Polymeric nanoantibiotics based on two orthogonal binding motifs coalesce with bacterial matter

ChemRxiv(2024)10.26434/chemrxiv-2024-k1wxk

N/A

0DataRank · unranked

1 citations

Eduardo Estrada, Jacob Deyell, Melody Sun, Albert R. La Spada, Seunghyun Sim +1 more

TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia

Journal of Clinical Investigation(2025)10.1172/jci182088

N/A

0DataRank · unranked

24 citations

Ya Cui, Sebastian Michels, Michael R. Colwin, Cameron Stockford, Wenbin Ye +19 more

An optimized variant prioritization process for rare disease diagnostics: recommendations for Exomiser and Genomiser

Genome Medicine(2025)10.1186/s13073-025-01546-1

N/A

0DataRank · unranked

8 citations

Shruti Marwaha, Alistair Ward, Shilpa N. Kobren, Jennefer N. Carter, Undiagnosed Diseases Network +94 more

Antibacterial Polymers Based on Two Orthogonal Binding Motifs Coalesce with Bacterial Matter

ACS Applied Bio Materials(2025)10.1021/acsabm.4c01872

N/A

0DataRank · unranked

4 citations

Eduardo Estrada, Jacob Deyell, Melody Sun, Albert R. La Spada, Seunghyun Sim +1 more

Neuromuscular junction transcriptome analysis of spinal and bulbar muscular atrophy mice implicates sarcomere gene expression and calcium flux dysregulation in disease pathogenesis

Human Molecular Genetics(2025)10.1093/hmg/ddaf074

N/A

0DataRank · unranked

1 citations

Byeonggu Cha, Nhat Nguyen, Diya Garg, Connor Coscolluela, Laura M. Strickland +6 more

PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

eLife(2025)10.7554/elife.107556

N/A

0DataRank · unranked

2 citations

Ryan Baumert, Gabrielle Séjourné, Dhanesh Sivadasan Bindu, Kylie Dimond, Kristina Sakers +12 more

Huntingtin preserves mitochondrial genome integrity in neurons, which is impaired in Huntington’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.24.666629

N/A

0DataRank · unranked

1 citations

Sagar Gaikwad, Chi-Lin Tsai, Charlene Smith, Nan Zhang, Keegan Bush +14 more

PQBP1-dependent alternative RNA splicing underlies high calorie diet-induced cognitive impairment

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.02.657545

N/A

0DataRank · unranked

0 citations

Hidenori Homma, Xigui Chen, Hikari Tanaka, Kyota Fujita, Albert R. La Spada +2 more

PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

eLife(2025)10.7554/elife.107556.1

N/A

0DataRank · unranked

0 citations

Ryan Baumert, Gabrielle Séjourné, Dhanesh Sivadasan Bindu, Kylie Dimond, Kristina Sakers +12 more

Bactericidal activities of copolymers incorporating formylphenyl motif for targeting surface proteins

ChemRxiv(2025)10.26434/chemrxiv-2025-qv01g

N/A

0DataRank · unranked

0 citations

Melody Sun, Michael R. Colwin, Albert R. La Spada, Seunghyun Sim, Esteban Bautista

Bactericidal Activities of Copolymers Incorporating Formylphenyl Motif for Targeting Surface Proteins

ACS Polymers Au(2025)10.1021/acspolymersau.5c00095

N/A

0DataRank · unranked

0 citations

Melody Sun, Michael R. Colwin, Albert R. La Spada, Seunghyun Sim, Esteban Bautista

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72

Nature Neuroscience(2020)10.1038/s41593-020-0619-5

N/A

0DataRank · unranked

235 citations

Jie Jiang, Tania F. Gendron, Melissa McAlonis‐Downes, Lu-Lin Jiang, Amy E. Taylor +13 more

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.17.692628

N/A

0DataRank · unranked

0 citations

Jonathan Hasselmann, Linda Stroud, Urmimala Raychaudhuri, Yunzi Guo, Byeonggu Cha +8 more

Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors

PLoS Genetics(2020)10.1371/journal.pgen.1008558

N/A

0DataRank · unranked

53 citations

Chandni Patel, Jaidev Bapat, Christian M. Jones, María Ramos Zapatero, Katherine K. Ortell +10 more

Albert R. La Spada

Indexed papers

Top data-sharing exemplar

Papers