Leo A. B. Joosten

Also affiliated with Iuliu Hațieganu University of Medicine and Pharmacy, Radboud University Medical Center

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 45 papers. Top paper: “Defining trained immunity and its role in health and disease”.

Defining trained immunity and its role in health and disease

Nature reviews. Immunology(2020)10.1038/s41577-020-0285-6

N/A

1.2DataRank · unranked

2393 citations

Jorge Domínguez‐Andrés, Luis B. Barreiro, Triantafyllos Chavakis, Maziar Divangahi, Elaine Fuchs +12 more

Linoleoyl-lysophosphatidylcholine suppresses immune-related adverse events due to immune checkpoint blockade

medRxiv(2024)10.1101/2024.08.07.24310974

N/A

0.208DataRank · unranked

3 citations

Priyanka Saminathan, Mir Henglin, Mingyue Liu, Namratha Nadig, Camille Fang +28 more

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

Nature Immunology(2020)10.1038/s41590-020-00845-6

N/A

0DataRank · unranked

603 citations

Peter Aaby, Shabaana A. Khader, Luis B. Barreiro, Siroon Bekkering, Triantafyllos Chavakis +39 more

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial

The Lancet Rheumatology(2020)10.1016/s2665-9913(20)30065-5

N/A

0DataRank · unranked

296 citations

Tim Jansen, M. Janssen, Antoaneta Comarniceanu, M. Efdé, Isak W. Tengesdal +8 more

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

BMC Bioinformatics(2020)10.1186/s12859-020-03576-5

N/A

0DataRank · unranked

78 citations

Niek de Klein, Jennifer Di Tommaso, Annique Claringbould, Monique G.P. van der Wijst, Dylan H. de Vries +23 more

Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout

Arthritis Research & Therapy(2020)10.1186/s13075-020-2136-z

N/A

0DataRank · unranked

62 citations

Amanda Phipps‐Green, Ruth Topless, Tanya J. Major, Murray Cadzow, Philip L. Riches +10 more

Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects

European Journal of Immunology(2020)10.1002/eji.201948390

N/A

0DataRank · unranked

33 citations

Martin Jaeger, Inge van den Munckhof, Rob ter Horst, Kiki Schraa, Jelle Zwaag +13 more

Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease

Cytokine(2020)10.1016/j.cyto.2020.155334

N/A

0DataRank · unranked

26 citations

Ralph J. A. Maas, Sanne P. Smeekens, Elan Eisenmesser, Jasmina S. Redzic, Monique M. Helsen +8 more

Impact of rare and common genetic variation in the Interleukin-1 pathway on human cytokine responses

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.14.949602

N/A

0DataRank · unranked

2 citations

Peer Arts, Giulio Cavalli, Martin Jaeger, Marloes Steehouwer, Maartje van de Vorst +9 more

Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout

Research Square(2020)10.21203/rs.2.20347/v2

N/A

0DataRank · unranked

2 citations

Amanda Phipps‐Green, Ruth Topless, Tanya J. Major, Murray Cadzow, Philip L. Riches +10 more

Pleiotropic effect of ABCG2 in gout: involvement in serum urate levels and progression from hyperuricemia to gout

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.06.894899

N/A

0DataRank · unranked

0 citations

Amanda Phipps‐Green, Ruth Topless, Tanya J. Major, Murray Cadzow, Philip L. Riches +10 more

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

Nature Communications(2021)10.1038/s41467-021-25213-2

N/A

0DataRank · unranked

93 citations

Godfrey S. Temba, Hera Vlamakis, Vesla Kullaya, Furaha S. Lyamuya, Blandina T. Mmbaga +6 more

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2000915118

N/A

0DataRank · unranked

194 citations

Dinoop Ravindran Menon, Douglas G. Osborne, C. Preston Neff, Nicholas E. Powers, Fabia Gamboni +17 more

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression

Frontiers in Immunology(2021)10.3389/fimmu.2021.661323

N/A

0DataRank · unranked

127 citations

Alberto Dinarello, Nicholas E. Powers, Matthew A. Burchill, Leo A. B. Joosten, Carlo Marchetti +2 more

Prosaposin mediates inflammation in atherosclerosis

Science Translational Medicine(2021)10.1126/scitranslmed.abe1433

N/A

0DataRank · unranked

102 citations

Thijs J. Beldman, Yohana C. Toner, Marnix Lameijer, Nils Rother, Siroon Bekkering +28 more

The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity

Cell Reports(2021)10.1016/j.celrep.2021.108955

N/A

0DataRank · unranked

72 citations

Isak W. Tengesdal, Mark S. Gresnigt, Travis Nemkov, Rob J.W. Arts, Jorge Domínguez‐Andrés +16 more

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

Genome biology(2021)10.1186/s13059-021-02413-z

N/A

0DataRank · unranked

70 citations

Martin Jaeger, Joep Beumer, Olivier B. Bakker, Raúl Aguirre‐Gamboa, Marije Oosting +28 more

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

JCI Insight(2021)10.1172/jci.insight.145928

N/A

0DataRank · unranked

69 citations

Lisa Van de Wijer, Farid Keramati, Wim Trypsteen, Sofie Rutsaert, Rob ter Horst +13 more

IL-1 family cytokines as drivers and inhibitors of trained immunity

Cytokine(2021)10.1016/j.cyto.2021.155773

N/A

0DataRank · unranked

69 citations

Rob J.W. Arts, Mihai G. Netea, Charles A. Dinarello, Leo A. B. Joosten, Lisa U. Teufel

Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes

Cell Reports(2021)10.1016/j.celrep.2021.110028

N/A

0DataRank · unranked

64 citations

Simone J.C.F.M. Moorlag, Ariel Lefkovith, Bihua Li, Vasiliki Matzaraki, Liesbeth van Emst +7 more

The influence of the gut microbiome on BCG-induced trained immunity

Genome biology(2021)10.1186/s13059-021-02482-0

N/A

0DataRank · unranked

51 citations

Vera P. Mourits, Valerie A. C. M. Koeken, L. Charlotte J. de Bree, Simone J.C.F.M. Moorlag, Leo A. B. Joosten +5 more

A modular approach toward producing nanotherapeutics targeting the innate immune system

Science Advances(2021)10.1126/sciadv.abe7853

N/A

0DataRank · unranked

47 citations

Anu E. Meerwaldt, Alexandre Berchouchi, Yohana C. Toner, Marianne E. Burnett, Emma D. Klein +24 more

Urate-induced epigenetic modifications in myeloid cells

Arthritis Research & Therapy(2021)10.1186/s13075-021-02580-1

N/A

0DataRank · unranked

46 citations

Orsolya I. Gaal, Maartje C. P. Cleophas, Viola Klück, Robab Davar, Ehsan Habibi +14 more

IL-38 prevents induction of trained immunity by inhibition of mTOR signaling

Journal of Leukocyte Biology(2021)10.1002/jlb.3a0220-143rrr

N/A

0DataRank · unranked

39 citations

Lisa U. Teufel, Frank L. van de Veerdonk, Leo A. B. Joosten, Mihai G. Netea, Charles A. Dinarello +2 more

Interleukin-38 in Health and Disease

Cytokine(2022)10.1016/j.cyto.2022.155824

N/A

0DataRank · unranked

38 citations

Lisa U. Teufel, Leo A. B. Joosten, Charles A. Dinarello, Dennis M. de Graaf

Activation of Host-NLRP3 Inflammasome in Myeloid Cells Dictates Response to Anti-PD-1 Therapy in Metastatic Breast Cancers

Pharmaceuticals(2022)10.3390/ph15050574

N/A

0DataRank · unranked

23 citations

Suzhao Li, Nicholas E. Powers, Makenna May, C. Preston Neff, Leo A. B. Joosten +3 more

IL-38 Gene Deletion Worsens Murine Colitis

Frontiers in Immunology(2022)10.3389/fimmu.2022.840719

N/A

0DataRank · unranked

16 citations

Ruth X. Wang, Jesús Amo‐Aparicio, J. Scott Lee, Alexander S. Dowdell, Isak W. Tengesdal +5 more

Circulating interleukin-38 concentrations in healthy adults

Frontiers in Immunology(2022)10.3389/fimmu.2022.964365

N/A

0DataRank · unranked

11 citations

Dennis M. de Graaf, Mihai G. Netea, Charles A. Dinarello, Leo A. B. Joosten, Rob J.W. Arts +1 more

Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients

Immunity Inflammation and Disease(2022)10.1002/iid3.712

N/A

0DataRank · unranked

1 citations

Lisa U. Teufel, Aline H. de Nooijer, Adriaan J. van Gammeren, Antonius A.M. Ermens, Ildikó O. Gaál +7 more

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

Nature Biomedical Engineering(2023)10.1038/s41551-023-01050-0

N/A

0DataRank · unranked

89 citations

Rutger J. Röring, Jeroen Deckers, Anne de Dreu, Yohana C. Toner, Geoffrey Prévot +27 more

A genome-wide association analysis reveals new pathogenic pathways in gout

Nature Genetics(2024)10.1038/s41588-024-01921-5

N/A

0DataRank · unranked

85 citations

Riku Takei, Hirotaka Matsuo, Megan Leask, Nicholas A. Sumpter, Ruth Topless +94 more

Polymersomes with splenic avidity target red pulp myeloid cells for cancer immunotherapy

Nature Nanotechnology(2024)10.1038/s41565-024-01727-w

N/A

0DataRank · unranked

31 citations

Jari F. Scheerstra, Mandy M. T. van Leent, Abraham J. P. Teunissen, Bram Priem, Thijs J. Beldman +30 more

Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro

Stem Cell Reports(2024)10.1016/j.stemcr.2024.09.004

N/A

0DataRank · unranked

28 citations

Willemijn Hobo, Diede van Ens, Elise L. Kessler, Boris Novakovic, Nicolaas Schaap +6 more

Candida albicans N-Linked Mannans Potentiate the Induction of Trained Immunity via Dectin-2

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae112

N/A

0DataRank · unranked

25 citations

Arnab Pradhan, Julia I. P. van Heck, Leonie Helder, Martin Jaeger, Neil A. R. Gow +6 more

Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling

Cell Reports(2024)10.1016/j.celrep.2024.114664

N/A

0DataRank · unranked

21 citations

Rianne Maas, Inge Jonkman, Y. Negishi, Willem Tielemans Zamora, Cansu Yanginlar +21 more

Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity

Cell Reports(2024)10.1016/j.celrep.2024.113932

N/A

0DataRank · unranked

15 citations

María Moreno, Lisa U. Teufel, Sofía Chilibroste, Samuel T. Keating, Laszlo Groh +11 more

Trained immunity suppression determines kidney allograft survival

American Journal of Transplantation(2024)10.1016/j.ajt.2024.08.006

N/A

0DataRank · unranked

11 citations

Maaike Jacobs, Y. Negishi, Cansu Yanginlar, Joost H.A. Martens, Marijke Baltissen +16 more

Plasma proteome adaptations during feminizing gender-affirming hormone therapy

Nature Medicine(2025)10.1038/s41591-025-04023-9

N/A

0DataRank · unranked

8 citations

Den Celestra, Lachlan M. Angus, Toby Mansell, Rebecca Shepherd, Bo Won Kim +14 more

C1q reprograms innate immune memory

Frontiers in Immunology(2025)10.3389/fimmu.2025.1515127

N/A

0DataRank · unranked

7 citations

Maaike Jacobs, Y. Negishi, Julia I. P. van Heck, Vasiliki Matzaraki, Joost H.A. Martens +12 more

Unveiling genetic signatures of immune response in immune-related diseases through single-cell eQTL analysis across diverse conditions

Nature Communications(2025)10.1038/s41467-025-61192-4

N/A

0DataRank · unranked

7 citations

Wenchao Li, Qiuyao Zhan, Michelle Aillaud, Javier Botey-Bataller, Martijn Zoodsma +9 more

Targeting mTOR in myeloid cells prevents infection-associated inflammation

iScience(2025)10.1016/j.isci.2025.112163

N/A

0DataRank · unranked

8 citations

Jazz Munitz, Geoffrey Prévot, Judit Morlà‐Folch, William Wang, Yuri van Elsas +38 more

Inflammatory markers in the cerebrospinal fluid linked to mortality in tuberculous meningitis

Brain Communications(2025)10.1093/braincomms/fcaf273

N/A

0DataRank · unranked

5 citations

Valerie A. C. M. Koeken, Edwin Ardiansyah, Ahmad Rizal Ganiem, Kirsten van Abeelen, Raúl Aguirre‐Gamboa +12 more

Interleukin-38 is a negative regulator of trained immunity—A retrospective multi-omics study

iScience(2025)10.1016/j.isci.2025.113758

N/A

0DataRank · unranked

2 citations

Vasiliki Matzaraki, Lukas Folkman, Dennis M. de Graaf, Rob ter Horst, Simone J.C.F.M. Moorlag +8 more

Sex differences in adenosine deaminase activity associate with disparities in SARS-CoV-2 innate immunity

iScience(2025)10.1016/j.isci.2025.112418

N/A

0DataRank · unranked

3 citations

Ian T. Mathews, Ahmad Alimadadi, Kai Fung, Kiyokazu Kakugawa, Leo A. B. Joosten +6 more

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

Cell(2020)10.1016/j.cell.2020.09.059

N/A

0DataRank · unranked

208 citations

Mandy M. T. van Leent, Abraham J. P. Teunissen, Alexandros Marios Sofias, Vera P. Mourits, Lisa Willemsen +40 more