Christopher M. Sassetti

University of Massachusetts Chan Medical School

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 49 papers. Top paper: “Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells”.

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

eLife(2021)10.7554/elife.65109

N/A

1.3DataRank · unranked

52 citations

Katelyn McCann, Daniel Mott, Steven M Holland, Samuel M. Behar, Christopher M. Sassetti +2 more

Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research

Genetics(2020)10.1534/genetics.120.303596

N/A

0.710DataRank · unranked

113 citations

Matthew W Blanchard, Ralph S. Baric, Timothy A. Bell, Jennifer Brennan, Gudrun A. Brockmann +64 more

Cell Wall Damage Reveals Spatial Flexibility in Peptidoglycan Synthesis and a Nonredundant Role for RodA in Mycobacteria

Journal of Bacteriology(2022)10.1128/jb.00540-21

N/A

0.670DataRank · unranked

22 citations

Takehiro Kado, Alam García‐Heredia, Kuldeepkumar Ramnaresh Gupta, Xavier Méniche, Yasu S Morita +4 more

Genome-wide screen of Mycobacterium tuberculosis-infected macrophages revealed GID/CTLH complex-mediated modulation of bacterial growth

Nature Communications(2024)10.1038/s41467-024-53637-z

N/A

0.598DataRank · unranked

26 citations

Luana Johnston, Paulina Pavinski Bitar, Eleni Jaecklein, Craig Altier, Christopher M. Sassetti +2 more

Host genetic background is a barrier to broadly effective vaccine–mediated protection against tuberculosis

Journal of Clinical Investigation(2023)10.1172/jci167762

N/A

0.546DataRank · unranked

37 citations

Diana Gong, Travis Williams, Abiola F. Ogunsola, Kelly Cavallo, Cecilia S. Lindestam Arlehamn +7 more

Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice

G3 Genes Genomes Genetics(2023)10.1093/g3journal/jkad147

N/A

0.536DataRank · unranked

15 citations

Jarukit E. Long, Adrián Jinich, Kyu Y. Rhee, David G. Ashbrook, Robert W. Williams +3 more

Modeling Site-Specific Nucleotide Biases Affecting Himar1 Transposon Insertion Frequencies in TnSeq Data Sets

mSystems(2021)10.1128/msystems.00876-21

N/A

0.406DataRank · unranked

14 citations

A. J. P. Brown, Chidiebere Akusobi, Eric J. Rubin, Christopher M. Sassetti, Thomas R. Ioerger +1 more

Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake

PLoS Pathogens(2023)10.1371/journal.ppat.1011650

N/A

0.396DataRank · unranked

13 citations

Bonnie J. Cuthbert, Thaís Klevorn, Alex Chao, Jessica Mendoza, Mark A. Arbing +8 more

Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice

Infection and Immunity(2023)10.1128/iai.00510-22

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0.396DataRank · unranked

13 citations

Rachel K. Meade, Emma Heckenberg, Jacob Dockterman, Jörn Coers, Christopher M. Sassetti +3 more

Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

eLife(2024)10.7554/elife.102980

N/A

0.395DataRank · unranked

9 citations

Eleni Jaecklein, Christopher M. Sassetti, David G. Russell, Nelson V. Simwela

The structure of Mycobacterium thermoresistibile MmpS5 reveals a conserved disulfide bond across mycobacteria

Metallomics(2024)10.1093/mtomcs/mfae011

N/A

0.312DataRank · unranked

7 citations

Jessica Mendoza, Rodger de Miranda, Kadamba Papavinasasundaram, Christopher M. Sassetti, Celia W. Goulding +1 more

The updated mouse universal genotyping array bioinformatic pipeline improves genetic QC in laboratory mice

G3 Genes Genomes Genetics(2024)10.1093/g3journal/jkae193

N/A

0.312DataRank · unranked

7 citations

John Sebastian Sigmon, Jennifer Brennan, Chidima Ahulamibe, Michelle E Allen, Sam Ardery +32 more

Mitochondrial respiration contributes to the interferon gamma response in antigen presenting cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.22.393538

N/A

0.269DataRank · unranked

5 citations

Daniel Mott, Samuel M. Behar, Christopher M. Sassetti, Andrew J. Olive, Michael C Kiritsy

The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis

mSphere(2023)10.1128/msphere.00389-22

N/A

0.269DataRank · unranked

5 citations

John T. Williams, John A. Buglino, Subhalaxmi Nambi, Lisa J. Lojek, Michael S. Glickman +3 more

Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2417525122

N/A

0.208DataRank · unranked

3 citations

Eun‐Ik Koh, Megan K. Proulx, Charlotte J. Reames, Kadamba Papavinasasundaram, Kenan C. Murphy +4 more

Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and Mycobacterium tuberculosis Infection

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.19.508548

N/A

0.165DataRank · unranked

2 citations

Diana Gong, Travis Williams, Abiola F. Ogunsola, Kelly Cavallo, Cecilia S. Lindestam Arlehamn +7 more

Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.08.439092

N/A

0.165DataRank · unranked

2 citations

Peter O. Oluoch, Nadine Ruecker, Megan K. Proulx, Vijay Soni, Kenan C. Murphy +19 more

Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2301394120

N/A

0DataRank · unranked

37 citations

Michael J. Luna, Luca Freschi, Maximillian G. Marin, Ruby Froom, Kenan C. Murphy +5 more

Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes

Nature Communications(2023)10.1038/s41467-023-41519-9

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0DataRank · unranked

27 citations

Lorissa J. Smulan, Michael L. Jameson, Clare M. Smith, Kelly Cavallo, Michelle M. Bellerose +6 more

High Bacillary Burden and the ESX-1 Type VII Secretion System Promote MHC Class I Presentation by Mycobacterium tuberculosis–Infected Macrophages to CD8 T Cells

The Journal of Immunology(2023)10.4049/jimmunol.2300001

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0DataRank · unranked

19 citations

Jason D. Yang, Christina E. Baer, Kadamba Papavinasasundaram, Christopher M. Sassetti, Samuel M. Behar +1 more

Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System

International Journal of Molecular Sciences(2023)10.3390/ijms24032861

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0DataRank · unranked

15 citations

Clare M. Smith, Christina E. Baer, Jörn Coers, Christopher M. Sassetti, Andrew J. Olive

Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.05.528534

N/A

0DataRank · unranked

0 citations

Jarukit E. Long, Adrián Jinich, Kyu Y. Rhee, David G. Ashbrook, Robert W. Williams +3 more

Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice

Nature Microbiology(2024)10.1038/s41564-024-01797-5

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0DataRank · unranked

38 citations

Gauri Prasad, Sandeep Upadhyay, Jully Sadadiwala, Andrew J. Olive, Guozhe Yang +3 more

Cross species modeling reveals a role for the unfolded protein response in shaping the transcriptional reaction to Mycobacterium tuberculosis infection

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.19.590290

N/A

0DataRank · unranked

1 citations

Ryan Finethy, Seung-Hyun B Ko, Charlotte J. Reames, Christopher M. Sassetti, Douglas A. Lauffenburger +1 more

The updated mouse universal genotyping array bioinformatic pipeline improves genetic QC in laboratory mice

UNC Libraries(2024)10.17615/vjs1-0445

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0DataRank · unranked

0 citations

Kelsey E. Noll, David Truong Nguyen, Megan K. Proulx, Marta C Cruz Cisneros, Pablo Hock +32 more

Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans

The Journal of Experimental Medicine(2025)10.1084/jem.20241760

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0DataRank · unranked

14 citations

Christine Davis, Charlotte J. Reames, Chin‐Jen Wu, Michael C Kiritsy, Ping Xu +9 more

Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction

Immunity(2025)10.1016/j.immuni.2025.05.004

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0DataRank · unranked

14 citations

Joshua M. Peters, Jaimie Sixsmith, Richard Lu, Edward B. Irvine, Corinne Luedeman +22 more

Targeted delivery of antitubercular drugs using glucan lipid particles

Microbiology Spectrum(2025)10.1128/spectrum.02744-24

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0DataRank · unranked

6 citations

Kadamba Papavinasasundaram, Gary R. Ostroff, Christopher M. Sassetti, Ernesto R. Soto, Eleni Jaecklein

Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection

npj Systems Biology and Applications(2025)10.1038/s41540-024-00487-6

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0DataRank · unranked

3 citations

Ryan Finethy, Seung-Hyun B Ko, Charlotte J. Reames, Christopher M. Sassetti, Douglas A. Lauffenburger +1 more

Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes

JCI Insight(2025)10.1172/jci.insight.194450

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0DataRank · unranked

1 citations

Denis Awany, Anele Gela, Temwa-Dango Mwambene, Sherry L. Kurtz, Richard E. Baker +5 more

Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

eLife(2025)10.7554/elife.102980.2

N/A

0DataRank · unranked

0 citations

Eleni Jaecklein, Christopher M. Sassetti, David G. Russell, Nelson V. Simwela

Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.05.652268

N/A

0DataRank · unranked

0 citations

Denis Awany, Anele Gela, Temwa-Dango Mwanbene, Christopher M. Sassetti, Thomas J. Scriba +2 more

Impaired autophagy in myeloid cell disrupts pulmonary B cell follicles and exacerbates chronic tuberculosis 2340

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.266

N/A

0DataRank · unranked

0 citations

K. Prasad, Sandeep K Upadhyay, Jully Sadadiwala, Andrew J. Olive, Christopher M. Sassetti +2 more

Granulocytes act as a niche for Mycobacterium tuberculosis growth

Mucosal Immunology(2020)10.1038/s41385-020-0300-z

N/A

0DataRank · unranked

110 citations

Christina E. Baer, Bibhuti B. Mishra, Clare M. Smith, Christopher M. Sassetti, Rustin R. Lovewell

CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis

PLoS Pathogens(2020)10.1371/journal.ppat.1008621

N/A

0DataRank · unranked

81 citations

Shayla Boyce, Jennifer Powers, Christina E. Baer, Christopher M. Sassetti, Samuel M. Behar +1 more

Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis

mSystems(2020)10.1128/msystems.00396-20

N/A

0DataRank · unranked

64 citations

Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, Christopher M. Sassetti +1 more

Phosphorylation on PstP Regulates Cell Wall Metabolism and Antibiotic Tolerance in Mycobacterium smegmatis

Journal of Bacteriology(2020)10.1128/jb.00563-20

N/A

0DataRank · unranked

15 citations

Kadamba Papavinasasundaram, Samantha Y. Quintanilla, Aditya C. Bandekar, Christopher M. Sassetti, Cara C. Boutte +1 more

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

PLoS Pathogens(2020)10.1371/journal.ppat.1009000

N/A

0DataRank · unranked

33 citations

Nathan Hicks, Shayla Boyce, Kenan C. Murphy, Kadamba Papavinasasundaram, Stephen M. Carpenter +7 more

Host-pathogen genetic interactions underlie tuberculosis susceptibility

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.405514

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0DataRank · unranked

6 citations

Richard E. Baker, Megan K. Proulx, Bibhuti B. Mishra, Jarukit E. Long, Sae Woong Park +21 more

Mycobacterium tuberculosis evasion of Guanylate Binding Protein-mediated host defense in mice requires the ESX1 secretion system

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.27.223362

N/A

0DataRank · unranked

2 citations

Clare M. Smith, Christina E. Baer, Jörn Coers, Christopher M. Sassetti, Andrew J. Olive

Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.21.260737

N/A

0DataRank · unranked

0 citations

Eleni Jaecklein, Jared S. Mackenzie, Kadamba Papavinasasundaram, Andrew J. Olive, Xinchun Chen +3 more

Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

PLoS Pathogens(2021)10.1371/journal.ppat.1008911

N/A

0DataRank · unranked

30 citations

Eleni Jaecklein, Jared S. Mackenzie, Kadamba Papavinasasundaram, Andrew J. Olive, Xinchun Chen +3 more

Characterization of Drug-Resistant Lipid-Dependent Differentially Detectable Mycobacterium tuberculosis

Journal of Clinical Medicine(2021)10.3390/jcm10153249

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0DataRank · unranked

9 citations

Seung-Hun Baek, Chuan-Chin Huang, Youngmi Kim, Sung‐Rae Cho, Thomas R. Ioerger +5 more

Modeling site-specific nucleotide biases affecting Himar1 transposon insertion frequencies in TnSeq datasets

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.01.450749

N/A

0DataRank · unranked

7 citations

A. J. P. Brown, Chidiebere Akusobi, Eric J. Rubin, Christopher M. Sassetti, Thomas R. Ioerger +1 more

Cell wall damage reveals spatial flexibility in peptidoglycan synthesis and a non-redundant role for RodA in mycobacteria

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.26.465981

N/A

0DataRank · unranked

6 citations

Takehiro Kado, Alam García‐Heredia, Kuldeepkumar Ramnaresh Gupta, Xavier Méniche, Yasu S Morita +4 more

REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk

The Journal of Immunology(2022)10.4049/jimmunol.2100671

N/A

0DataRank · unranked

9 citations

Alex J. Warr, Andrew D. Graustein, Aparajita Saha, Sarah J. Dunstan, Nguyễn Thụy Thương Thương +21 more

Two‐way regulation of protein expression for identification and validation of on‐target inhibitors of Mycobacterium tuberculosis

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7723

N/A

0DataRank · unranked

0 citations

Curtis A. Engelhart, Esther Perez‐Herran, Divya Tiwari, Wei Li, Katherine A. Abrahams +9 more

High bacillary burden and the ESX-1 type VII secretion system promote MHC class I presentation by Mycobacterium tuberculosis infected macrophages to CD8 T-cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.20.513087

N/A

0DataRank · unranked

0 citations

Jason D. Yang, Christina E. Baer, Kadamba Papavinasasundaram, Christopher M. Sassetti, Samuel M. Behar +1 more

Differential requirement for IRGM proteins during tuberculosis infection in mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.09.515519

N/A

0DataRank · unranked

0 citations

Rachel K. Meade, Emma Heckenberg, Jacob Dockterman, Jörn Coers, Christopher M. Sassetti +3 more