Alexandria M. Chan

Also affiliated with University of Utah, Huntsman Cancer Institute

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 9 papers. Top paper: “Shifting the paradigm in treating multi-factorial diseases: polypharmacological co-inhibitors of HDAC6”.

Shifting the paradigm in treating multi-factorial diseases: polypharmacological co-inhibitors of HDAC6

RSC Medicinal Chemistry(2020)10.1039/d0md00286k

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0DataRank · unranked

12 citations

Steven Fletcher, Alexandria M. Chan

Recent applications of covalent chemistries in protein–protein interaction inhibitors

RSC Medicinal Chemistry(2022)10.1039/d2md00112h

N/A

0DataRank · unranked

15 citations

Christopher C. Goodis, Elie G. Pommier, Steven Fletcher, Alexandria M. Chan

1‐Sulfonylated 1,2,3,4‐tetrahydroquinoline‐6‐carboxylic acids as simple, readily‐accessible MCL‐1 inhibitors

Drug Development Research(2022)10.1002/ddr.22004

N/A

0DataRank · unranked

4 citations

Alexandria M. Chan, Paul T. Wilder, Steven Fletcher, Lijia Chen

The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN–GIL hybrid single-molecule inhibitors

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.117190

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0DataRank · unranked

7 citations

Christian Eberly, Alexandria M. Chan, Minjung Kim, Brandon D. Lowe, Curt I. Civin +2 more

Histone deacetylase (HDAC) inhibitor specificity determinants are preserved in a class of dual HDAC/non-covalent proteasome inhibitors

Bioorganic & Medicinal Chemistry(2024)10.1016/j.bmc.2024.117680

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0DataRank · unranked

6 citations

Ashley Mitchell, Lena Grogan, Paul Shapiro, Steven Fletcher, Alexandria M. Chan

diaPASEF-Powered Chemoproteomics Enables Deep Kinome Interaction Profiling

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.22.624841

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0DataRank · unranked

2 citations

Thankhoe A. Rants’o, Alexandria M. Chan, Tanmay Sapre, Grace E. Mastin, Kathleen M. Maguire +3 more

Augmenting the Anti‐Leukemic Activity of the BCL‐2 Inhibitor Venetoclax Through Its Transformation Into Polypharmacologic Dual BCL‐2/HDAC1 and Dual BCL‐2/HDAC6 Inhibitors

Drug Development Research(2025)10.1002/ddr.70084

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0DataRank · unranked

5 citations

Christian Eberly, Brandon Drennen, Christopher C. Goodis, Zoe Wuyts, Curt I. Civin +2 more

First-in-Class Potent, Dual HDAC6/Proteasome Inhibitors Lacking a Hydroxamic Acid Motif: Discovery of Novel Anti-Multiple Myeloma Agents

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.5c00500

N/A

0DataRank · unranked

3 citations

Brandon D. Lowe, Andrea L. Cottingham, Daniel Van Eker, Asaminew H. Aytenfisu, Jace W. Jones +4 more

Multiomic Analyses Reveal Brainstem Metabolic Changes in a Mouse Model of Dravet Syndrome

Cells(2025)10.3390/cells15010067

N/A

0DataRank · unranked

0 citations

Alexandria M. Chan, Audrey Scholl, Aidan J. Mulligan, Janint Camacho, Ireland Rose Kearns +9 more