Damian J. Krysan

MedicineBiochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “A single Leishmania adenylate–forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA”.

A single Leishmania adenylate–forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107879

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0.241DataRank · unranked

4 citations

Taiwo E. Esan, Jonah Propp, Andrew Fuller, Drashti G. Daraji, Charles L. Lail +8 more

Enantioselective Synthesis of (+)-Hippolide J and Reevaluation of Antifungal Activity

Organic Letters(2020)10.1021/acs.orglett.0c02979

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7 citations

Sarah R. Beattie, Damian J. Krysan, M. Kevin Brown, Renyu Guo

The Ndr/LATS kinase Cbk1 regulates a specific subset of Ace2 functions and suppresses the hyphae-to-yeast transition in Candida albicans

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.10.198242

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0 citations

Laura C. Ristow, Mark A. Stamnes, Anuj Kumar, Damian J. Krysan, Rohan S. Wakade

A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus

mSphere(2021)10.1128/msphere.00539-21

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18 citations

Damian J. Krysan, Sarah R. Beattie

The Cbk1-Ace2 axis guides Candida albicans from yeast to hyphae and back again

Current Genetics(2021)10.1007/s00294-020-01152-1

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15 citations

Damian J. Krysan, Rohan S. Wakade

Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2A Δ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis

mSphere(2021)10.1128/msphere.00830-21

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14 citations

Bao Gia Vu, Daniel Murante, Josie E. Parker, Lucia Šimoničová, Laura A. Doorley +6 more

Loss-of-function ROX1 mutations suppress the fluconazole susceptibility of upc2A Δ mutation in Candida glabrata , implicating additional positive regulators of ergosterol biosynthesis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.07.463606

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1 citations

Bao Gia Vu, Daniel Murante, Josie E. Parker, Lucia Šimoničová, Laura A. Doorley +6 more

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans

eLife(2022)10.7554/elife.82563

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30 citations

Tuyetnhu Pham, Xiaofeng Xie, Laura C. Ristow, Damian J. Krysan, Xiaorong Lin +1 more

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Journal of Visualized Experiments(2022)10.3791/64258

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11 citations

Damian J. Krysan, Melanie Wellington, Rohan S. Wakade

Candida albicans filamentation does not require the cAMP-PKA pathway in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.25.485899

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0 citations

Juraj Kamara, Melanie Wellington, Damian J. Krysan, Rohan S. Wakade

FKS1 is required for Cryptococcus neoformans fitness in vivo : application of copper-regulated gene expression to mouse models of cryptococcosis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.24.485727

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0DataRank · unranked

0 citations

Andrew J. Jezewski, Laura C. Ristow, Melanie Wellington, Damian J. Krysan, Sarah R. Beattie

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Journal of Visualized Experiments(2022)10.3791/64258-v

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0 citations

Damian J. Krysan, Melanie Wellington, Rohan S. Wakade

The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and oral commensalism

mBio(2023)10.1128/mbio.01521-23

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39 citations

Juraj Kramara, Tomye Ollinger, Norma V. Solis, Robert Żarnowski, Rohan S. Wakade +10 more

Candida albicans Oropharyngeal Infection Is an Exception to Iron-Based Nutritional Immunity

mBio(2023)10.1128/mbio.00095-23

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19 citations

Rohan S. Wakade, Scott G. Filler, Damian J. Krysan, Norma V. Solis

Carbon Dioxide Potentiates Flucytosine Susceptibility in Cryptococcus neoformans

Microbiology Spectrum(2023)10.1128/spectrum.04783-22

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12 citations

Laura C. Ristow, Damian J. Krysan, Andrew J. Jezewski

Novel Keto-Alkyl-Pyridinium Antifungal Molecules Active in Models of In Vivo Candida albicans Vascular Catheter Infection and Ex Vivo Candida auris Skin Colonization

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.00081-23

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11 citations

Taiwo E. Esan, Robert Żarnowski, Emily F. Eix, Jeniel E. Nett, David R. Andes +3 more

CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.00567-23

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12 citations

Sarah R. Beattie, Soumitra Guin, Thomas P. Conway, Marvin J. Meyers, W. Scott Moye‐Rowley +2 more

The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition

Frontiers in Oncology(2023)10.3389/fonc.2023.1295185

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7 citations

Anita Venzke, Soumitra Guin, Andrew Fuller, Andrew J. Jezewski, Sarah R. Beattie +4 more

Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor

Acta Crystallographica Section F Structural Biology Communications(2023)10.1107/s2053230x23003801

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2 citations

Madison Bolejack, Taiwo E. Esan, Damian J. Krysan, Timothy J. Hagen, Jan Abendroth +1 more

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain-dependent

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.15.571891

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0DataRank · unranked

1 citations

Melanie Wellington, Damian J. Krysan, Rohan S. Wakade

Candida albicans oropharyngeal infection is an exception to iron-based nutritional immunity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.11.523704

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0DataRank · unranked

0 citations

Rohan S. Wakade, Scott G. Filler, Damian J. Krysan, Norma V. Solis

Novel keto-alkyl-pyridinium antifungal molecules active in models of in vivo Candida albicans vascular catheter infection and ex vivo Candida auris skin colonization

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.19.524835

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0DataRank · unranked

0 citations

Taiwo E. Esan, Robert Żarnowski, Emily F. Eix, Jeniel E. Nett, David R. Andes +3 more

CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.01.538946

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0DataRank · unranked

0 citations

Sarah R. Beattie, Soumitra Guin, Thomas P. Conway, Marvin J. Meyers, W. Scott Moye‐Rowley +2 more

Comparative dynamics of gene expression during in vitro and in vivo Candida albicans filamentation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.21.558874

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0 citations

Damian J. Krysan, Rohan S. Wakade

Systematic analysis of the Candida albicans kinome reveals environmentally contingent protein kinase-mediated regulation of filamentation and biofilm formation in vitro and in vivo

mBio(2024)10.1128/mbio.01249-24

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11 citations

Min-Ju Kim, Tomye L. Ollinger, Laura C. Ristow, Rohan S. Wakade, Robert Żarnowski +5 more

Temporal dynamics of Candida albicans morphogenesis and gene expression reveals distinctions between in vitro and in vivo filamentation

mSphere(2024)10.1128/msphere.00110-24

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10 citations

Melanie Wellington, Damian J. Krysan, Rohan S. Wakade

Synthesis and Antifungal Activity of Stereoisomers of Mefloquine Analogs

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00031

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7 citations

Katy M. Alden, Damian J. Krysan, Marvin J. Meyers, Soumitra Guin

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent

mSphere(2024)10.1128/msphere.00785-23

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0DataRank · unranked

10 citations

Melanie Wellington, Damian J. Krysan, Rohan S. Wakade

Analogs of the anti-malaria drug mefloquine have broad-spectrum antifungal activity and are efficacious in a model of disseminated Candida auris infection

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01301-24

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1 citations

Marhiah C. Montoya, Xiaoyu Wang, Robert Żarnowski, David R. Andes, Marvin J. Meyers +3 more

Temporal dynamics of Candida albicans morphogenesis and gene expression reveals distinctions between in vitro and in vivo filamentation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.20.581211

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2 citations

Melanie Wellington, Damian J. Krysan, Rohan S. Wakade

Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.19.613905

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0 citations

Bao Gia Vu, Sarah R. Beattie, Damian J. Krysan, W. Scott Moye‐Rowley, Thomas P. Conway

Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs

mSphere(2024)10.1128/msphere.00792-24

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0DataRank · unranked

0 citations

Bao Gia Vu, Sarah R. Beattie, Damian J. Krysan, W. Scott Moye‐Rowley, Thomas P. Conway

An improved synthesis of alkyl AMP esters

Tetrahedron Letters(2024)10.1016/j.tetlet.2024.155329

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0DataRank · unranked

0 citations

Charles L. Lail, Drashti G. Daraji, Damian J. Krysan, Timothy J. Hagen, Taiwo E. Esan

Microevolution of Cryptococcus neoformans in high CO2 converges on mutations isolated from patients with relapsed cryptococcosis

Cell Reports(2025)10.1016/j.celrep.2025.115349

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8 citations

Laura C. Ristow, Edith Blackburn, Xiaofeng Xie, Damian J. Krysan, Xiaorong Lin +1 more

Second generation repurposing of phenothiazine antipsychotic drugs as antifungal lead molecules via optimization of phenoxazine derivatives

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118373

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2 citations

Katy M. Alden, Emily Harshbarger, Laurie C. Ristow, Andrew J. Jezewski, Damian J. Krysan +2 more

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor

Nature Communications(2025)10.1038/s41467-025-64183-7

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2 citations

Katy M. Alden, Jonah Propp, Drashti G. Daraji, Charles L. Lail, Michael E. Heene +10 more

Gene dosage and protein valency impact phase separation and fungal cell fate

PLoS Genetics(2025)10.1371/journal.pgen.1011810

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1 citations

Puming He, Corey Frazer, Damian J. Krysan, Richard J. Bennett, Collin Ganser

Antifungal Structure–Activity Relationship Studies of Broad-Spectrum Phenothiazines

ACS Omega(2025)10.1021/acsomega.4c09833

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1 citations

Soumitra Guin, Gregory Giovine, Carlos Gadalla, Miguel A. Campos, Alisa Mara +7 more

Discovery and mechanism of a highly selective, antifungal acetyl CoA synthetase inhibitor

Research Square(2025)10.21203/rs.3.rs-5619443/v1

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1 citations

Damian J. Krysan

Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2

Cell chemical biology(2020)10.1016/j.chembiol.2019.12.008

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0DataRank · unranked

61 citations

Álvaro Lorente‐Macías, P.J. Stogios, E. Evdokimova, Sabrina Hyde, Melanie Wellington +11 more

Synthesis and evaluation of acyl-AMP phosphate isosteres as inhibitors of fungal acetyl CoA synthetase

Bioorganic & Medicinal Chemistry Letters(2025)10.1016/j.bmcl.2025.130389

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0DataRank · unranked

0 citations

Andrew J. Jezewski, Katy M. Alden, Jonah Propp, Michael E. Heene, Calvin A Soldan +7 more