🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Natalia Mast

Case Western Reserve University

ORCID: 0000-0001-6427-640X

MedicinePharmacology, Toxicology and PharmaceuticsBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 15 papers. Top paper: “Cholestenoic Acid Is an Important Elimination Product of Cholesterol in the Retina: Comparison of Retinal Cholesterol Metabolism with That in the Brain”.

Cholestenoic Acid Is an Important Elimination Product of Cholesterol in the Retina: Comparison of Retinal Cholesterol Metabolism with That in the Brain

Investigative Opthalmology & Visual Science(2011)10.1167/iovs.10-6021

N/A

0.688DataRank · unranked

97 citations

Rachel Reem, Ilya Bederman, Suber Huang, Pier Luigi DiPatre, Ingemar Bjorkhem +2 more

CYP46A1 activation by low-dose efavirenz enhances brain cholesterol metabolism in subjects with early Alzheimer’s disease

Alzheimer s Research & Therapy(2022)10.1186/s13195-022-01151-z

N/A

0.546DataRank · unranked

37 citations

Steven E. Arnold, Erin Maxfield, Aaron Koenig, Maria E. Toth, Brooke Fortin +8 more

Cholesterol crystal formation is a unifying pathogenic mechanism in the development of diabetic retinopathy

Diabetologia(2023)10.1007/s00125-023-05949-w

N/A

0.489DataRank · unranked

25 citations

Tim F. Dorweiler, Delaney McFarland, Yvonne Adu-Agyeiwaah, Natalia Mast, Nicole El‐Darzi +8 more

Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100555

N/A

0.330DataRank · unranked

8 citations

Makaya Butts, Irina A. Pikuleva, Natalia Mast

The normalizing effects of the CYP46A1 activator efavirenz on retinal sterol levels and risk factors for glaucoma in Apoj−/− mice

Cellular and Molecular Life Sciences(2023)10.1007/s00018-023-04848-y

N/A

0.269DataRank · unranked

5 citations

Natalia Mast, Yong Li, Brian Dailey, Min Hyung Kang, Douglas J. Rhee +2 more

The Hydroxylation Position Rather than Chirality Determines How Efavirenz Metabolites Activate Cytochrome P450 46A1 In Vitro

Drug Metabolism and Disposition(2022)10.1124/dmd.122.000874

N/A

0.241DataRank · unranked

4 citations

Anna Fotinich, Irina A. Pikuleva, Natalia Mast

2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis

Journal of Lipid Research(2022)10.1016/j.jlr.2022.100323

N/A

0DataRank · unranked

5 citations

Natalia Mast, Sandra S. Hammer, Tim F. Dorweiler, Julia V. Busik, Irina A. Pikuleva +1 more

Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1917421117

N/A

0DataRank · unranked

89 citations

Roberto Angelini, Mark Baumert, Natalia Mast, Irina A. Pikuleva, Jillian Newton +6 more

CYP46A1 Activation By Low-Dose Efavirenz Enhances Brain Cholesterol Metabolism In Subjects With Mild Cognitive Impairment Due To Alzheimer’s Disease

Research Square(2022)10.21203/rs.3.rs-1348328/v1

N/A

0DataRank · unranked

0 citations

Steven E. Arnold, Erin Maxfield, Aaron Koenig, Mária Tóth, Brooke Fortin +8 more

Characterizations of Hamster Retina as a Model for Studies of Retinal Cholesterol Homeostasis

Biology(2021)10.3390/biology10101003

N/A

0DataRank · unranked

10 citations

Natalia Mast, Brian Dailey, John A. Denker, Yong Li, Joseph E. Vance +2 more

Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters

Journal of Lipid Research(2023)10.1016/j.jlr.2023.100401

N/A

0DataRank · unranked

10 citations

Nicole El‐Darzi, Yong Li, Irina A. Pikuleva, Natalia Mast

2‐Hydroxypropyl‐β‐cyclodextrin reduces retinal cholesterol in wild‐type and Cyp27a1−/−Cyp46a1−/− mice with deficiency in the oxysterol production

British Journal of Pharmacology(2020)10.1111/bph.15209

N/A

0DataRank · unranked

30 citations

Natalia Mast, Alexey M. Petrov, Irina A. Pikuleva, Nicole El‐Darzi

APOB100 transgenic mice exemplify how the systemic circulation content may affect the retina without altering retinal cholesterol input

Cellular and Molecular Life Sciences(2024)10.1007/s00018-023-05056-4

N/A

0DataRank · unranked

9 citations

Natalia Mast, Yong Li, Irina A. Pikuleva, Nicole El‐Darzi

Synthesis and pharmacokinetic study of a 11C-labeled cholesterol 24-hydroxylase inhibitor using ‘in-loop’ [11C]CO2 fixation method

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127068

N/A

0DataRank · unranked

11 citations

Jiahui Chen, Natalia Mast, Jian Rong, Xiaoyun Deng, Tuo Shao +9 more

CYP46A1-dependent and independent effects of efavirenz treatment

Brain Communications(2020)10.1093/braincomms/fcaa180

N/A

0DataRank · unranked

22 citations

Nicole El‐Darzi, Alexey M. Petrov, Young Li, Irina A. Pikuleva, Natalia Mast