🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

John Ravits

Columbia University Irving Medical Center

ORCID: 0000-0001-6521-4649

Also affiliated with University of California San Diego

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile
0.874Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Human motor neurons are rare and can be transcriptomically divided into known subtypes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.05.535689
Top 37%
0.530DataRank
Top 37%10 citations

Jacob A. Blum, James Maksymetz, Derek Chen, Christoph Schweingruber, Irene Mei +6 more

Papers

Driven by 25 papers — median percentile 56. Top paper: “A framework for sharing of clinical and genetic data for precision medicine applications”.

A framework for sharing of clinical and genetic data for precision medicine applications

Nature Medicine(2024)10.1038/s41591-024-03239-5
N/A
0.857DataRank · unranked
32 citations

Ulugbek K. Baymuradov, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach +63 more

Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis

EBioMedicine(2024)10.1016/j.ebiom.2024.105323
N/A
0.856DataRank · unranked
46 citations

Eric A. Macklin, Andrea Malaspina, Mary‐Louise Rogers, Eran Hornstein, Vittoria Lombardi +25 more

TDP-43 loss induces cryptic polyadenylation in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02050-w
N/A
0.593DataRank · unranked
23 citations

Anna‐Leigh Brown, Max Z. Y. J. Chien, Dario Dattilo, Puja R. Mehta, Francesca Mattedi +94 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

iScience(2021)10.1016/j.isci.2021.103221
N/A
0.593DataRank · unranked
51 citations

Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono +92 more

Human motor neurons are rare and can be transcriptomically divided into known subtypes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.05.535689
Top 37%
0.530DataRank
Top 37%10 citations

Jacob A. Blum, James Maksymetz, Derek Chen, Christoph Schweingruber, Irene Mei +6 more

Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis

Acta Neuropathologica(2021)10.1007/s00401-021-02374-4
N/A
0.500DataRank · unranked
27 citations

Vivian I. Ko, Sonia Vazquez‐Sanchez, Ruth Chia, Olubankole Aladesuyi Arogundade, María José Gómez-Rodríguez +4 more

Effectiveness of long-term noninvasive ventilation measured by remote monitoring in neuromuscular disease

ERJ Open Research(2023)10.1183/23120541.00163-2023
Top 51%
0.344DataRank
Top 51%4 citations

Kenneth S. Chen, Florin Vaida, Christopher N. Schmickl, Chamindra G. Laverty, John Ravits +5 more

Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.14.464447
N/A
0.292DataRank · unranked
6 citations

Jiaojiao Hu, Bankhole Aladesuyi, Alexander Goginashvili, Sonia Vazquez‐Sanchez, Jolene K. Diedrich +9 more

Radiogenomics ofC9orf72Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment

Journal of Neuroscience(2022)10.1523/jneurosci.1448-22.2022
N/A
0DataRank · unranked
12 citations

Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang +20 more

Radiogenomics of C9orf72 expansion carriers reveals global transposable element de-repression and enables prediction of thalamic atrophy and clinical impairment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.28.501897
N/A
0DataRank · unranked
2 citations

Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang +20 more

Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation

Nature Neuroscience(2023)10.1038/s41593-023-01496-0
N/A
0DataRank · unranked
49 citations

Mariana Bravo‐Hernández, Maximiliano Presa, Michael W. Baughn, Ze’ev Melamed, Melinda S. Beccari +21 more

Challenges of profiling motor neuron transcriptomes from human spinal cord

Neuron(2023)10.1016/j.neuron.2023.10.035
N/A
0DataRank · unranked
28 citations

Jacob A. Blum, James Maksymetz, Derek Chen, Christoph Schweingruber, Irene Mei +6 more

Somatic mosaicism in amyotrophic lateral sclerosis and frontotemporal dementia identifies focal mutations associated with widespread degeneration

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.30.569436
N/A
0DataRank · unranked
3 citations

Jun‐Ho Kim, August Yue Huang, Matthew Nolan, Junseok Park, Ryan N. Doan +19 more

CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation

Neurobiology of Disease(2024)10.1016/j.nbd.2024.106516
N/A
0DataRank · unranked
20 citations

Kailee Ong, Don W. Cleveland, Haiyang Yu, John Ravits, Vivian I. Ko

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis

Acta Neuropathologica Communications(2024)10.1186/s40478-024-01902-z
N/A
0DataRank · unranked
7 citations

Kailee Ong, Deborah Y. Kwon, Xueying Li, Alicia Pietrasiewicz, James Harvey +5 more

Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy

Acta Neuropathologica(2024)10.1007/s00401-024-02732-y
N/A
0DataRank · unranked
7 citations

Alex Meng, John Ravits, Isabel Costantino

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72

Nature Neuroscience(2020)10.1038/s41593-020-0619-5
N/A
0DataRank · unranked
235 citations

Jie Jiang, Tania F. Gendron, Melissa McAlonis‐Downes, Lu-Lin Jiang, Amy E. Taylor +13 more

Shared burden of ultra-rare genetic variants across a spectrum of motor neuron diseases

Translational Neurodegeneration(2025)10.1186/s40035-025-00516-2
N/A
0DataRank · unranked
1 citations

Wenan Chen, Joanne Wuu, Angita Jain, Jason R. Myers, Isabell Cordts +26 more

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

Nature Communications(2020)10.1038/s41467-020-14312-1
N/A
0DataRank · unranked
60 citations

Isaac A. Chaim, Jorge A. Benítez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner +16 more

Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis

EMBO Molecular Medicine(2020)10.15252/emmm.202012595
N/A
0DataRank · unranked
28 citations

Michael Benatar, Joanne Wuu, Evadnie Rampersaud, Laura Hennessy, Vivianna M. Van Deerlin +29 more

Nucleolar stress in C9orf72 and sporadic ALS spinal motor neurons precedes TDP-43 mislocalization

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01125-6
N/A
0DataRank · unranked
37 citations

Sandra Nguyen, Ringo Leung, Danielle Wainio, María José Gómez-Rodríguez, John Ravits +1 more

Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition

Research Square(2021)10.21203/rs.3.rs-933368/v1
N/A
0DataRank · unranked
13 citations

Jiaojiao Hu, Bankhole Aladesuyi, Alexander Goginashvili, Sonia Vazquez‐Sanchez, Jolene K. Diedrich +9 more

Nuclear depletion of RNA binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.03.446017
N/A
0DataRank · unranked
6 citations

Vivian I. Ko, Sonia Vazquez‐Sanchez, Ruth Chia, Olubankole Aladesuyi Arogundade, María José Gómez-Rodríguez +4 more

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature(2022)10.1038/s41586-022-04436-3
N/A
0DataRank · unranked
525 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee +90 more

Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis

Acta Neuropathologica(2022)10.1007/s00401-022-02450-3
N/A
0DataRank · unranked
23 citations

Emily C. Wheeler, Martin Regensburger, Tom Boerstler, Holger Wend, Anthony Q. Vu +10 more