William B. Isaacs

Johns Hopkins University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

10.5Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Papers

Driven by 36 papers — median percentile 0. Top paper: “Pan-cancer analysis of whole genomes”.

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

JCI Insight(2021)10.1172/jci.insight.146827

N/A

1.5DataRank · unranked

58 citations

Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel +16 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial

Cancer Prevention Research(2020)10.1158/1940-6207.capr-19-0450

N/A

0DataRank · unranked

9 citations

İbrahim Kulaç, Berrak Gümüşkaya, Javier Baena-Del Valle, Inés Benedetti, Fan Pan +13 more

Genomic and Clinicopathologic Characterization of ATM -deficient Prostate Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-0764

N/A

0DataRank · unranked

42 citations

Daniela C. Salles, Sanjana Murali, Jessica Hicks, Minh Nguyen, Colin C. Pritchard +8 more

Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer

European Urology(2020)10.1016/j.eururo.2020.07.038

N/A

0DataRank · unranked

42 citations

Shannon K. McDonnell, Liesel M. FitzGerald, Lissa DeRycke, Zachary C. Fogarty, Graham G. Giles +34 more

Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for prostate cancer Genetics using novel sumLINK and sumLOD analyses

UNC Libraries(2020)10.17615/cv63-ck59

N/A

0DataRank · unranked

0 citations

Ingrid Oakley‐Girvan, Douglas F. Easton, Gianluca Severi, Stephen N. Thibodeau, Alice S. Whittemore +27 more

Genome-wide Scan of 29,141 African Americans Finds No Evidence of Directional Selection since Admixture

UNC Libraries(2020)10.17615/2zpw-wt34

N/A

0DataRank · unranked

0 citations

Graham Casey, Adam B. Murphy, Michael F. Press, Cathryn H. Bock, Melinda C. Aldrich +27 more

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry

UNC Libraries(2020)10.17615/g911-ez39

N/A

0DataRank · unranked

0 citations

Benjamin A. Rybicki, Janet L. Stanford, William B. Isaacs, Sonja I. Berndt, Esther M. John +16 more

Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease

UNC Libraries(2020)10.17615/ba4b-zw14

N/A

0DataRank · unranked

0 citations

Anna M. Ray, Kathleen A. Cooney, Douglas F. Easton, Christiane Maier, Géraldine Cancel‐Tassin +27 more

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21

UNC Libraries(2020)10.17615/3mny-1202

Top 100%

0DataRank

Top 100%0 citations

Rosalind A. Eeles, Melissa C. Southey, Olivier Cussenot, Kathleen A. Cooney, Johanna Schleutker +36 more

Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer

UNC Libraries(2020)10.17615/wk90-0y29

N/A

0DataRank · unranked

0 citations

William B. Isaacs, Jianfeng Xu, Waibov A. Tembe, Elena M. Stoffel, Christiane M. Robbins +8 more

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

UNC Libraries(2020)10.17615/azx9-qr47

N/A

0DataRank · unranked

0 citations

Fredrik Wiklund, Michael J. Ackerman, Kathleen A. Cooney, Zsofia Kote‐Jarai, Elaine A. Ostrander +27 more

Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer

UNC Libraries(2020)10.17615/84ka-ac36

N/A

0DataRank · unranked

0 citations

Jessica V. Ribado, Jin Li, Qing Duan, Anna Marie Johnson, William B. Isaacs +11 more

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

UNC Libraries(2020)10.17615/gd7n-3n77

Top 100%

0DataRank

Top 100%0 citations

Olivier Cussenot, Diptasri Mandal, Nilah M. Ioannidis, Graham G. Giles, Shannon K. McDonnell +36 more

Germline Mutations in HOXB13 and Prostate-Cancer Risk

UNC Libraries(2020)10.17615/14fr-m757

N/A

0DataRank · unranked

0 citations

Patrick C. Walsh, Kimberly A. Zuhlke, Waibhav Tembe, Guifang Yan, Sarah D. Isaacs +20 more

Homologous recombination deficiency (HRD) score in germline BRCA2- versus ATM-altered prostate cancer

Modern Pathology(2021)10.1038/s41379-020-00731-4

N/A

0DataRank · unranked

118 citations

Harsimar Kaur, Daniela C. Salles, Sanjana Murali, Edward M. Schaeffer, Jerry S. Lanchbury +8 more

Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study

European Urology Oncology(2021)10.1016/j.euo.2020.12.001

N/A

0DataRank · unranked

73 citations

Mark N. Brook, Tokhir Dadaev, Sarah Wakerell, Edward J. Saunders, Kenneth Muir +38 more

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG)

UNC Libraries(2021)10.17615/ktmt-6886

N/A

0DataRank · unranked

6 citations

Kimberly A. Zuhlke, Nicola J. Camp, Zsofia Kote‐Jarai, Lingyi Lu, Nancy Hamel +45 more

Health inequity drives disease biology to create disparities in prostate cancer outcomes

Journal of Clinical Investigation(2022)10.1172/jci155031

N/A

0DataRank · unranked

39 citations

Otis W. Brawley, William B. Isaacs, Elizabeth A. Platz, Srinivasan Yegnasubramanian, Karen S. Sfanos +3 more

A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry

European Urology(2022)10.1016/j.eururo.2021.12.023

N/A

0DataRank · unranked

48 citations

Raymond W. Hughley, Aaron Pfennig, Ujani Hazra, C.P.S. Fan, Peggy Wan +95 more

Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing

Molecular Cancer Research(2022)10.1158/1541-7786.mcr-21-0683

N/A

0DataRank · unranked

8 citations

Anuj Gupta, Harshath Gupta, Ajay Vaghasia, Alyza Skaist, McKinzie A. Garrison +10 more

Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry

European Urology(2023)10.1016/j.eururo.2023.01.022

N/A

0DataRank · unranked

51 citations

Ravi Madduri, Alex A Rodriguez, Burcu F. Darst, Alisha Chou, Xin Sheng +95 more

FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-genomic Features of Prostate Cancer

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0248

N/A

0DataRank · unranked

10 citations

Lia DePaula Oliveira, Ethan Schaffer, Thiago Vidotto, Adrianna A. Mendes, Jiayun Lu +11 more

Characterization of HOXB13 expression patterns in localized and metastatic castration‐resistant prostate cancer

The Journal of Pathology(2023)10.1002/path.6216

N/A

0DataRank · unranked

26 citations

Erolcan Sayar, Ilsa Coleman, Martine P. Roudier, Brian Hanratty, Jin‐Yih Low +23 more

Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry

The American Journal of Human Genetics(2023)10.1016/j.ajhg.2023.05.010

N/A

0DataRank · unranked

25 citations

Jiayi Shen, Ravi Madduri, Alexis Rodriguez, Yukai Xiao, Xin Sheng +95 more

Clinical and Functional Analyses of an African-ancestry Gain-of-function HOXB13 Variant Implicated in Aggressive Prostate Cancer

European Urology Oncology(2023)10.1016/j.euo.2023.09.012

N/A

0DataRank · unranked

11 citations

Yidong Chen, Daniel Rabizadeh, Lauren Vera, Changxue Lu, Sarah M. Nielsen +7 more

De novo variants identified by trio whole exome sequencing of bladder exstrophy epispadias complex

American Journal of Medical Genetics Part A(2023)10.1002/ajmg.a.63501

N/A

0DataRank · unranked

3 citations

Elizabeth Wohler, Renan Paulo Martin, Heather N. Di Carlo, William B. Isaacs, Joan Ko +6 more

Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry

medRxiv(2023)10.1101/2023.05.12.23289860

N/A

0DataRank · unranked

2 citations

Jiayi Shen, Ravi Madduri, Alexis Rodriguez, Yukai Xiao, Xin Sheng +95 more

Data from Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent

(2023)10.1158/1055-9965.c.6514782.v1

Top 100%

0DataRank

Top 100%0 citations

Elaine Spangler, Stephen Gallagher, Christopher A. Haiman, Brian E. Henderson, William B. Isaacs +29 more

Data from Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent

(2023)10.1158/1055-9965.c.6514782

Top 100%

0DataRank

Top 100%0 citations

Elaine Spangler, Stephen Gallagher, Christopher A. Haiman, Brian E. Henderson, William B. Isaacs +29 more

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry

UNC Libraries(2023)10.17615/fjrp-xk90

N/A

0DataRank · unranked

0 citations

Shiv Srivastava, Marie‐Élise Parent, Peter E. Clark, Kosj Yamoah, Mark Sanderson +67 more

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Nature Communications(2022)10.1038/s41467-022-32343-8

N/A

0DataRank · unranked

0 citations

PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal, Samirkumar B. Amin, Pratiti Bandopadhayay, Rameen Beroukhim +1242 more

Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors

Oncogene(2020)10.1038/s41388-020-01479-6

N/A

0DataRank · unranked

105 citations

Susan L. Dalrymple, Ilsa M. Coleman, Shun Zheng, Jianfeng Xu, Jody E. Hooper +10 more

Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

Nature Communications(2020)10.1038/s41467-020-18843-5

N/A

0DataRank · unranked

79 citations

Е. В. Рябченко, Sinja Taavitsainen, Matti Kankainen, Gunes Gundem, Daniel Brewer +13 more

William B. Isaacs

Indexed papers

Top data-sharing exemplar

Papers