Yann Le Guen

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 44 papers. Top paper: “Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference”.

Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference

Alzheimer s & Dementia(2024)10.1002/alz.13877

N/A

1.1DataRank · unranked

33 citations

Michaël E. Belloy, Elizabeth Blue, Gregory R. Bowman, María C. Carrillo, Xiaoying Chen +55 more

Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease

Acta Neuropathologica(2024)10.1007/s00401-024-02721-1

N/A

1.1DataRank · unranked

52 citations

Tamil Iniyan Gunasekaran, Michaël E. Belloy, Dolly Reyes‐Dumeyer, Dörthe Jülich, Hüseyin Tayran +25 more

Organ aging signatures in the plasma proteome track health and disease

Nature(2023)10.1038/s41586-023-06802-1

N/A

0.957DataRank · unranked

588 citations

Jarod Rutledge, Daniel Nachun, Róbert Pálovics, Olamide Abiose, Patricia Moran‐Losada +31 more

A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease

Nature Medicine(2025)10.1038/s41591-025-03565-2

N/A

0.688DataRank · unranked

97 citations

Deniz Yagmur Urey, Linda Karlsson, Zeyu Zhu, Yuanyuan Shen, Amelia Farinas +33 more

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease

JAMA Neurology(2022)10.1001/jamaneurol.2022.1166

N/A

0.681DataRank · unranked

93 citations

Michaël E. Belloy, Benjamin Grenier‐Boley, Itziar de Rojas, Atahualpa Castillo-Morales, Iris E. Jansen +95 more

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease

Nature Genetics(2024)10.1038/s41588-024-01972-8

N/A

0.639DataRank · unranked

70 citations

Jigyasha Timsina, Lihua Wang, Ciyang Wang, Chengran Yang, Carlos Cruchaga +37 more

Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum

Neuron(2025)10.1016/j.neuron.2025.02.014

N/A

0.601DataRank · unranked

54 citations

Jigyasha Timsina, Daniel Western, Menghan Liu, Aleksandra Beric, John Budde +24 more

Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

Molecular Neurodegeneration(2024)10.1186/s13024-023-00687-4

N/A

0.601DataRank · unranked

54 citations

Niko-Petteri Nykänen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li +28 more

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s disease

Research Square(2023)10.21203/rs.3.rs-2814616/v1

N/A

0.561DataRank · unranked

41 citations

Daniel Western, Jigyasha Timsina, Lihua Wang, Ciyang Wang, Chengran Yang +26 more

Role of the X Chromosome in Alzheimer Disease Genetics

JAMA Neurology(2024)10.1001/jamaneurol.2024.2843

N/A

0.533DataRank · unranked

34 citations

Yann Le Guen, Ilaria Stewart, Kennedy Williams, Joachim Herz, Richard Sherva +9 more

Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping

Alzheimer s Research & Therapy(2022)10.1186/s13195-022-00962-4

N/A

0.464DataRank · unranked

21 citations

Sarah J. Eger, Yann Le Guen, Vincent Damotte, Shahzad Ahmad, M Arfan Ikram +24 more

Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease.

Research Square(2024)10.21203/rs.3.rs-3631708/v1

N/A

0.406DataRank · unranked

14 citations

Muhammad Ali, Yuanyuan Shen, Anh Do, Lihua Wang, Daniel Western +23 more

Cardiac Troponin Screening and Clinical Outcomes in Patients Receiving Immunotherapy

JACC CardioOncology(2025)10.1016/j.jaccao.2025.06.009

N/A

0.385DataRank · unranked

12 citations

Maja Ivanovic, Antonia Chan, Sidra Xu, Miguel Franquiz, Carissa Lee +19 more

Loop diuretics association with Alzheimer’s disease risk

Frontiers in Aging(2023)10.3389/fragi.2023.1211571

N/A

0.373DataRank · unranked

11 citations

Justin Lee, Kyan Younes, Michael D. Greicius, Yann Le Guen, Zihuai He +1 more

Clonal Hematopoiesis Mutations Increase Risk of Alzheimer’s Disease with APOE ε3/ε3 Genotype

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.19.654981

N/A

0.311DataRank · unranked

3 citations

Kyung Park, Yann Le Guen, Jong-Ho Park, Zinan Zhou, Liz Enyenihi +7 more

Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.22.604680

N/A

0.269DataRank · unranked

5 citations

Deniz Yagmur Urey, Linda Karlsson, Zeyu Zhu, Yuanyuan Shen, Amelia Farinas +28 more

Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

medRxiv(2023)10.1101/2023.06.14.23291409

N/A

0.208DataRank · unranked

3 citations

Niko-Petteri Nykänen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li +26 more

Challenges at the APOE locus: A robust quality control approach for accurate APOE genotyping

medRxiv(2021)10.1101/2021.10.19.21265022

N/A

0.165DataRank · unranked

2 citations

Sarah J. Eger, Yann Le Guen, Vincent Damotte, Shahzad Ahmad, M Arfan Ikram +24 more

Improving genetic risk prediction across diverse population by disentangling ancestry representations

Communications Biology(2023)10.1038/s42003-023-05352-6

N/A

0DataRank · unranked

18 citations

Yann Le Guen, Xiaoxia Liu, Michaël E. Belloy, Hua Tang, James Zou +2 more

Sex‐ and APOE‐specific genetic risk factors for late‐onset Alzheimer's disease: Evidence from gene–gene interaction of longevity‐related loci

Aging Cell(2023)10.1111/acel.13938

N/A

0DataRank · unranked

14 citations

Francesco De Rango, Paolina Crocco, Stefano Pallotti, Michaël E. Belloy, Yann Le Guen +5 more

Summary statistics knockoff inference empowers identification of putative causal variants in genome-wide association studies

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.06.471440

N/A

0DataRank · unranked

2 citations

Linxi Liu, Michaël E. Belloy, Yann Le Guen, Aaron Sossin, Xiaoxia Liu +9 more

A 3’UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP

medRxiv(2023)10.1101/2023.07.06.23292312

N/A

0DataRank · unranked

11 citations

Yann Le Guen, Yi Zeng, John E. Gorzynski, Tanner Jensen, Chengran Yang +13 more

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s Disease pathology

medRxiv(2023)10.1101/2023.07.20.23292771

N/A

0DataRank · unranked

5 citations

Yann Le Guen, Sunny Chen, Eun-Gyung Lee, Lesley Leong, John E. Gorzynski +18 more

Bumetanide Exposure Association with Alzheimer’s Disease Risk

Research Square(2023)10.21203/rs.3.rs-2574215/v1

N/A

0DataRank · unranked

2 citations

Justin Lee, Kyan Younes, Michael D. Greicius, Yann Le Guen, Zihuai He +1 more

A fast and robust strategy to remove variant level artifacts in Alzheimer’s Disease Sequencing Project data

medRxiv(2021)10.1101/2021.10.28.21265577

N/A

0DataRank · unranked

2 citations

Yann Le Guen, Sarah J. Eger, Valerio Napolioni, Michael D. Greicius, Zihuai He +1 more

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.08.434451

N/A

0DataRank · unranked

4 citations

Linxi Liu, Chen Wang, Yann Le Guen, Justin Lee, Stephanie M. Gogarten +8 more

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s disease pathology

Neuron(2024)10.1016/j.neuron.2024.01.008

N/A

0DataRank · unranked

41 citations

Yann Le Guen, Sunny Chen, Eun-Gyung Lee, Lesley Leong, John E. Gorzynski +23 more

Plasma Aβ 42 /Aβ 40 is sensitive to early cerebral amyloid accumulation and predicts risk of cognitive decline across the Alzheimer's disease spectrum

Alzheimer s & Dementia(2024)10.1002/alz.14442

N/A

0DataRank · unranked

37 citations

Christina B. Young, Hillary Vossler, Javier Ramos Benitez, Karly Alex Cody, Jaime Mendiola +30 more

A novel age-informed approach for genetic association analysis in Alzheimer’s disease

medRxiv(2021)10.1101/2021.01.05.21249292

N/A

0DataRank · unranked

4 citations

Michaël E. Belloy, Valerio Napolioni, Sarah J. Eger, Gabriel Kennedy, Ran Tao +4 more

A 3′UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated With Increased Risk for FTLD-TDP

Neurology Genetics(2024)10.1212/nxg.0000000000200124

N/A

0DataRank · unranked

12 citations

Yann Le Guen, Yi Zeng, John E. Gorzynski, Tanner Jensen, Chengran Yang +13 more

Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference

Alzheimer s & Dementia(2024)10.1002/alz.14291

N/A

0DataRank · unranked

6 citations

Simin Mahinrad, Christopher J. Barnum, André F. Batista, Elizabeth M. Bradshaw, Brittany Butts +37 more

KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers

Neurobiology of Aging(2021)10.1016/j.neurobiolaging.2021.01.008

N/A

0DataRank · unranked

21 citations

Sarah J. Eger, Yann Le Guen, Valerio Napolioni, Kacie Deters, Hyun‐Sik Yang +13 more

Beyond guilty by association at scale: searching for causal variants on the basis of genome-wide summary statistics

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.28.582621

N/A

0DataRank · unranked

5 citations

Benjamin B. Chu, James Yang, Jiaqi Gu, Zhaomeng Chen, Linxi Liu +12 more

The Role of X Chromosome in Alzheimer’s Disease Genetics

medRxiv(2024)10.1101/2024.04.22.24306094

N/A

0DataRank · unranked

5 citations

Yann Le Guen, Ilaria Stewart, Joachim Herz, Richard Sherva, Rui Zhang +9 more

Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.10.009

N/A

0DataRank · unranked

30 citations

Yann Le Guen, Linxi Liu, Justin Lee, Shiyang Ma, Andrew C. Yang +13 more

A novel age-informed approach for genetic association analysis in Alzheimer’s disease

Alzheimer s Research & Therapy(2021)10.1186/s13195-021-00808-5

N/A

0DataRank · unranked

39 citations

Yann Le Guen, Michaël E. Belloy, Valerio Napolioni, Sarah J. Eger, Gabriel Kennedy +4 more

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

Nature Communications(2021)10.1038/s41467-021-22889-4

N/A

0DataRank · unranked

42 citations

Linxi Liu, Chen Wang, Yann Le Guen, Justin Lee, Stephanie M. Gogarten +8 more

Synaptic proteins that aggregate and degrade slower with aging accumulate in microglia

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.20.654652

N/A

0DataRank · unranked

1 citations

Viktoria Wagner, Patricia Moran Losada, Sophia M. Shi, Kelly Chen, Barbara T Meese +14 more

CD44 cross-linking promotes Plasmodium falciparum invasion

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.30.667750

N/A

0DataRank · unranked

0 citations

S.W. Scally, Yann Le Guen, Praveesh Valissery, Nichole D. Salinas, Alan F. Cowman +3 more

Deep neural networks with controlled variable selection for the identification of putative causal genetic variants

Nature Machine Intelligence(2022)10.1038/s42256-022-00525-0

N/A

0DataRank · unranked

18 citations

Fred Lu, Yann Le Guen, Michaël E. Belloy, Zihuai He, Peyman Hosseinzadeh Kassani

Common X-chromosome variants are associated with Parkinson’s disease risk

medRxiv(2020)10.1101/2020.12.18.20248459

N/A

0DataRank · unranked

5 citations

Valerio Napolioni, Michaël E. Belloy, Eric Yu, Lynne Krohn, Jennifer A. Ruskey +5 more

Improving genetic risk prediction across diverse population by disentangling ancestry representations

Research Square(2022)10.21203/rs.3.rs-1829520/v1

N/A

0DataRank · unranked

4 citations

Yann Le Guen, Xiaoxia Liu, Hua Tang, James Zou, Zihuai He +1 more

GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies

Nature Communications(2022)10.1038/s41467-022-34932-z

N/A

0DataRank · unranked

29 citations

Linxi Liu, Michaël E. Belloy, Yann Le Guen, Aaron Sossin, Xiaoxia Liu +10 more

Association ofKlotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who CarryAPOE4

JAMA Neurology(2020)10.1001/jamaneurol.2020.0414

N/A

0DataRank · unranked

116 citations

Valerio Napolioni, Summer S. Han, Yann Le Guen, Michael D. Greicius, for the Alzheimer’s Disease Neuroimaging Initiative +1 more