Alan E. Renton

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.435Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in DIAN

medRxiv(2024)10.1101/2024.08.08.24311689

Top 52%

0.331DataRank

Top 52%7 citations

Eric McDade, Jorge J. Llibre‐Guerra, Johannes Levin, Richard J. Perrin, Laura Ibáñez +37 more

Papers

Driven by 50 papers — median percentile 35. Top paper: “The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease”.

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Nature(2020)10.1038/s41586-020-2681-2

N/A

8.5DataRank · unranked

398 citations

Georgia Frost, Xianzhong Wu, Christina J. Crump, Si Pan, Eitan Wong +26 more

Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups

Brain(2021)10.1093/brain/awab402

N/A

1.4DataRank · unranked

66 citations

Zalak Shah, Ruth Chia, Sandra E. Black, Ziv Gan‐Or, Julia Keith +81 more

17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes

Molecular Neurodegeneration(2022)10.1186/s13024-022-00551-x

N/A

1.3DataRank · unranked

60 citations

Derian A. Pugh, Yiyuan Liu, Tulsi Patel, Alan E. Renton, Sara Bandrés‐Ciga +15 more

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial

The Lancet Neurology(2025)10.1016/s1474-4422(25)00024-9

N/A

1.2DataRank · unranked

41 citations

Yan Li, Eric McDade, Jorge J. Llibre‐Guerra, David B. Clifford, Alireza Atri +62 more

Association ofBDNFVal66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease

JAMA Neurology(2022)10.1001/jamaneurol.2021.5181

N/A

1.2DataRank · unranked

37 citations

Paul Maruff, Nicolas R. Barthélemy, Alison Goate, Jason Hassenstab, Chihiro Sato +87 more

Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease

JAMA Neurology(2024)10.1001/jamaneurol.2024.0991

N/A

1.0DataRank · unranked

29 citations

Haiyan Liu, Guoqiao Wang, Xinyu Shi, Tobias Bittner, Marzia A. Scelsi +94 more

The complex genetic architecture of Alzheimer's disease: novel insights and future directions

EBioMedicine(2023)10.1016/j.ebiom.2023.104511

N/A

0.888DataRank · unranked

371 citations

Alan E. Renton, Brian Fulton‐Howard, Anna Podlesny‐Drabiniok, Edoardo Marcora, Alison Goate +1 more

Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease

Nature Medicine(2023)10.1038/s41591-023-02476-4

N/A

0.781DataRank · unranked

181 citations

Shijia Bian, Rafi U. Haque, Kathleen Carter, Caroline M Watson, Brian A. Gordon +93 more

Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study

The Lancet Neurology(2022)10.1016/s1474-4422(21)00375-6

N/A

0.652DataRank · unranked

76 citations

Stephanie A. Schultz, Eric McDade, Aaron P. Schultz, Lei Liu, Bernard Hanseeuw +34 more

CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease

Cell(2024)10.1016/j.cell.2024.08.049

N/A

0.628DataRank · unranked

65 citations

Jigyasha Timsina, Gyujin Heo, Aleksandra Beric, Muhammad Ali, Ciyang Wang +88 more

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

Nature Communications(2024)10.1038/s41467-024-52025-x

N/A

0.568DataRank · unranked

43 citations

Jack Humphrey, Timothy S. Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa +55 more

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Acta Neuropathologica(2021)10.1007/s00401-021-02379-z

N/A

0.553DataRank · unranked

39 citations

SoongHo Kim, Natalia Han, Megan A. Iida, Elias Gonzalez, Marcos Otero‐García +84 more

Genome‐Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene

Journal of the American Heart Association(2023)10.1161/jaha.123.031459

N/A

0.533DataRank · unranked

18 citations

Andrew Bakshi, Gerald F. Watts, Alan E. Renton, Brian Fulton‐Howard, Alison Goate +12 more

γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)

The Lancet Neurology(2024)10.1016/s1474-4422(24)00236-9

N/A

0.529DataRank · unranked

33 citations

Lei Liu, Aaron P. Schultz, Colleen Fitzpatrick, Raina Levin, Jean‐Pierre Bellier +94 more

Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease

Nature Communications(2024)10.1038/s41467-024-52937-8

N/A

0.510DataRank · unranked

29 citations

Lisa M. Häsler, Marius Lambert, Stephan A. Kaeser, Susanne Gräber‐Sultan, Ulrike Obermüller +88 more

Novel TARDBP Sequence Variant and C9ORF72 Repeat Expansion in a Family With Frontotemporal Dementia

Alzheimer Disease & Associated Disorders(2014)10.1097/wad.0b013e318266fae5

N/A

0.457DataRank · unranked

20 citations

Virpi Moilanen, Marko Kervinen, Alan E. Renton, Bryan J. Traynor, Kari Majamaa +2 more

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.09.565552

N/A

0.456DataRank · unranked

11 citations

Jack Humphrey, Timothy S. Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa +42 more

Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred

Alzheimer s & Dementia(2023)10.1002/alz.13021

N/A

0.449DataRank · unranked

19 citations

Juliana Acosta‐Uribe, Bianca Esposito, Lucía Madrigal, David Aguillón, Margarita Giraldo +25 more

Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2021)10.1002/dad2.12226

N/A

0.442DataRank · unranked

18 citations

Brian Fulton‐Howard, Moeen Riaz, Simon M. Laws, Robert Sebra, Joanne Ryan +11 more

Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal‐dominant Alzheimer's disease

Aging Cell(2023)10.1111/acel.13871

N/A

0.426DataRank · unranked

11 citations

Zahra Shirzadi, Aaron P. Schultz, Lei Liu, Colleen Fitzpatrick, Eric McDade +42 more

Investigation of the genetic aetiology of Lewy body diseases with and without dementia

Brain Communications(2024)10.1093/braincomms/fcae190

N/A

0.385DataRank · unranked

12 citations

Raquel Real, Alejandro Martínez-Carrasco, Ruth Chia, Michael Lawton, Maryam Shoai +93 more

Systematic proteomics in Autosomal dominant Alzheimer’s disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways

medRxiv(2024)10.1101/2024.01.12.24301242

N/A

0.373DataRank · unranked

11 citations

Muhammad Ali, Jigyasha Timsina, Ciyang Wang, Anh Do, Daniel Western +32 more

Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging

EBioMedicine(2024)10.1016/j.ebiom.2024.105080

N/A

0.373DataRank · unranked

11 citations

Austin McCullough, Brian A. Gordon, Charles D. Chen, Nicole S. McKay, Diana A. Hobbs +86 more

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial

medRxiv(2024)10.1101/2024.10.29.24316289

N/A

0.351DataRank · unranked

6 citations

Yan Li, Eric McDade, Jorge J. Llibre‐Guerra, David B. Clifford, Alireza Atri +63 more

Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease

Annals of Clinical and Translational Neurology(2023)10.1002/acn3.51757

N/A

0.345DataRank · unranked

9 citations

Annie Lee, Dolly Reyes‐Dumeyer, Giuseppe Tosto, Kelley Faber, Alison Goate +15 more

Ubiquitin–proteasome system in the different stages of dominantly inherited Alzheimer's disease

Alzheimer s & Dementia(2025)10.1002/alz.70243

N/A

0.345DataRank · unranked

9 citations

Quoc Bui, Jason Hassenstab, Brian A. Gordon, Tammie L.S. Benzinger, Jigyasha Timsina +32 more

15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in DIAN

medRxiv(2024)10.1101/2024.08.08.24311689

Top 52%

0.331DataRank

Top 52%7 citations

Eric McDade, Jorge J. Llibre‐Guerra, Johannes Levin, Richard J. Perrin, Laura Ibáñez +37 more

Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2021)10.1002/dad2.12255

N/A

0.330DataRank · unranked

8 citations

William S. Bush, Alan E. Renton, Edoardo A. Marcora, Joshua C. Bis, Brian W. Kunkle +13 more

Frequency of Variants in Mendelian Alzheimer’s Disease Genes within the Alzheimer’s Disease Sequencing Project (ADSP)

medRxiv(2023)10.1101/2023.10.24.23297227

N/A

0.292DataRank · unranked

6 citations

Alexandra Scalici, Yanbing Wang, Honghuang Lin, Achilleas Pitsillides, Nancy L. Heard‐Costa +16 more

Association of cardiovascular disease management drugs with Lewy body dementia: a case–control study

Brain Communications(2023)10.1093/braincomms/fcad346

N/A

0.292DataRank · unranked

6 citations

Brian Moroz, Sara Sáez-Atiénzar, Ruth Chia, Elizabeth K. Cahoon, Clifton L. Dalgard +93 more

Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data

Cell Genomics(2024)10.1016/j.xgen.2024.100679

N/A

0.292DataRank · unranked

6 citations

Cleide Dos Santos Souza, Ruth Chia, Selina N. Beal, Ileana Lorenzini, Ruili Huang +92 more

Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease

Acta Neuropathologica(2025)10.1007/s00401-025-02890-7

N/A

0.292DataRank · unranked

6 citations

Erin Franklin, Yan Li, Nelly Joseph‐Mathurin, Aime Burns, Diana A. Hobbs +93 more

Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry

JVS Vascular Science(2020)10.1016/j.jvssci.2020.09.001

N/A

0.241DataRank · unranked

4 citations

Alan E. Renton, Ella Taubenfeld, Rami O. Tadros, Edoardo Marcora, R. Lookstein +3 more

O2‐10‐06: A Common Allele in SPI1 Lowers Risk and Delays Age at Onset for Alzheimer's Disease

Alzheimer's & Dementia(2016)10.1016/j.jalz.2016.06.453

N/A

0.241DataRank · unranked

4 citations

Sheng Chih Jin, Oscar Harari, Manav Kapoor, Sarah Bertelsen, Jake Czajkowski +36 more

Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer’s disease

Brain(2025)10.1093/brain/awaf106

N/A

0.208DataRank · unranked

3 citations

Logan Dumitrescu, Derek B. Archer, Alexandra N. Regelson, Shubhabrata Mukherjee, Michael L. Lee +58 more

Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population

medRxiv(2020)10.1101/2020.10.11.20210963

N/A

0.104DataRank · unranked

1 citations

Aamira Huq, Joanne Ryan, Suzanne G. Orchard, Jane Tiller, Jessica E. Lockery +13 more

The National Institute on Aging Late Onset Alzheimer’s Disease Family Based Study: A Critical Component of the International Effort to Understand Alzheimer’s Disease

medRxiv(2021)10.1101/2021.04.12.21255332

Top 78%

0.104DataRank

Top 78%1 citations

Kelley Faber, Badri N. Vardarajan, Alison Goate, Alan E. Renton, Michael J. Chao +12 more

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis

JAMA Neurology(2021)10.1001/jamaneurol.2021.2598

N/A

0DataRank · unranked

85 citations

Ruth Chia, Danny E. Miller, Rachel Li, Ravindran Kumaran, Yevgeniya Abramzon +87 more

The Role of Genomic-Informed Risk Assessments in Predicting Dementia Outcomes

medRxiv(2024)10.1101/2024.04.27.24306488

N/A

0DataRank · unranked

1 citations

Paulina Tolosa-Tort, Mary B. Makarious, Brian Fulton‐Howard, Alan E. Renton, Jennifer S. Yokoyama +3 more

Dementia Risk Scores, APOE, and risk of Alzheimer disease: one size does not fit all

medRxiv(2024)10.1101/2024.04.27.24306486

N/A

0DataRank · unranked

0 citations

Ana I Boeriu, Michaël E. Belloy, Alan E. Renton, Brian Fulton‐Howard, Willa D. Brenowitz +3 more

A Genome-Wide Association Study of Myasthenia Gravis

UNC Libraries(2020)10.17615/hk4s-3m41

N/A

0DataRank · unranked

0 citations

Emanuela Bartoccioni, Michael A. Nalls, Mamatha Pasnoor, Mario Sabatelli, April McVey +27 more

CASP8 intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2416885122

N/A

0DataRank · unranked

7 citations

Ramadan Ajredini, Shu Guo, Lisa E. L. Romano, Rodrigo F. Tomas, Logan Bell +25 more

Integrative effects of Telomere Length, Epigenetic Age, and Mitochondrial DNA abundance in Alzheimer’s Disease

medRxiv(2025)10.1101/2025.07.16.25331683

N/A

0DataRank · unranked

0 citations

Rakshya U Sharma, Brendan A. Mitchell, Tong Tong, Luke W. Bonham, Alan E. Renton +6 more

Remote Digital Cognitive Assessment in a Trial-Ready Alzheimer’s Cohort: A Scalable Approach for Early Intervention Studies

(2025)10.31234/osf.io/mz62t_v1

N/A

0DataRank · unranked

0 citations

Hannah Wilks, Matthew S. Welhaf, Samhita Katteri, Sarah H. Stout, Martin J. Sliwinski +19 more

Unraveling the complex role of MAPT-containing H1 and H2 haplotypes in neurodegenerative diseases

Molecular Neurodegeneration(2024)10.1186/s13024-024-00731-x

N/A

0DataRank · unranked

33 citations

Sarah A. Weitzman, Alan E. Renton, Alison Goate, Chiara Pedicone

Social determinants of health but not global genetic ancestry predict dementia prevalence in Latin America

Alzheimer s & Dementia(2024)10.1002/alz.14041

N/A

0DataRank · unranked

28 citations

Miao Jiang, Isaac Acosta, Ana Luisa Sosa, Daisy Acosta, Ivonne Z. Jimenez‐Velasquez +11 more

Validation of newly derived polygenic risk scores for dementia in a prospective study of older individuals

Alzheimer s & Dementia(2023)10.1002/alz.13113

N/A

0DataRank · unranked

23 citations

Joanne Ryan, Suzanne G. Orchard, Catherine Robb, Robyn L. Woods, Rory Wolfe +13 more

Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2108672119

N/A

0DataRank · unranked

133 citations

Sara Sáez-Atiénzar, Natalie A. Murphy, Adriano Chiò, Cornelis Blauwendraat, Ricardo H. Roda +48 more

The role of genomic‐informed risk assessments in predicting dementia outcomes

Alzheimer s & Dementia(2025)10.1002/alz.70826

N/A

0DataRank · unranked

0 citations

Paulina Tolosa‐Tort, Mary B. Makarious, Brian Fulton‐Howard, Alan E. Renton, Jennifer S. Yokoyama +3 more

Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population

Aging Cell(2021)10.1111/acel.13384

N/A

0DataRank · unranked

49 citations

Aamira Huq, Joanne Ryan, Suzanne G. Orchard, Jane Tiller, Jessica E. Lockery +13 more

Alan E. Renton

Indexed papers

Top data-sharing exemplar

Papers