Michael A. Brehm

University of Massachusetts Chan Medical School

Immunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 34 papers. Top paper: “Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV‐1 pathogenesis”.

Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV‐1 pathogenesis

The EMBO Journal(2023)10.15252/embj.2023114153

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0.636DataRank · unranked

20 citations

Lawrence M. Lifshitz, Noah J. Silverstein, Esther Mintzer, Kevin Luk, Pamela StLouis +5 more

Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells

Cell Reports(2020)10.1016/j.celrep.2020.107894

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83 citations

Elad Sintov, Torsten Meißner, Michael A. Brehm, Dale L. Greiner, David M. Harlan +2 more

A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic‐related cytokine release syndrome

The FASEB Journal(2020)10.1096/fj.202001203r

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62 citations

Hongyuan Yang, Mingshan Cheng, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm +2 more

Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge

Microorganisms(2020)10.3390/microorganisms8020295

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14 citations

Agata Jurczyk, Basanthi Satish, Sambra D. Redick, Natasha Qaisar, Melanie I. Trombly +9 more

Humanized mice for immune system investigation: progress, promise and challenges

UNC Libraries(2020)10.17615/yar2-3h52

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0 citations

Dale L. Greiner, Leonard D. Shultz, J. Víctor García, Michael A. Brehm

An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis

Molecular Therapy(2021)10.1016/j.ymthe.2021.11.007

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46 citations

Nicole Wetoska, Mark Kelly, Dimas Echeverria, Kyounghee Min, Lawrence M. Lifshitz +13 more

Modeling human T1D-associated autoimmune processes

Molecular Metabolism(2021)10.1016/j.molmet.2021.101417

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40 citations

Rachel Madley, Chiara Borsotti, Leonardo M. R. Ferreira, Robert C. Sharp, Michael A. Brehm +6 more

Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg null mice expressing human IL15

The FASEB Journal(2022)10.1096/fj.202200045r

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56 citations

Lisa Burzenski, Li‐Chin Yao, James Keck, Dale L. Greiner, Leonard D. Shultz +2 more

Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model

Methods in molecular biology(2022)10.1007/978-1-0716-1971-1_18

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3 citations

Stephen J. Libby, Joyce E. Karlinsey, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz +3 more

Humanized mouse models for immuno-oncology research

Nature Reviews Clinical Oncology(2023)10.1038/s41571-022-00721-2

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0DataRank · unranked

371 citations

Hannah Buettner, Mina O. Seedhom, Dale L. Greiner, James Keck, Fumihiko Ishikawa +3 more

γδ T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors

Nature Cancer(2023)10.1038/s43018-023-00589-w

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69 citations

Alexandra Zaborowski, Haim Moore, Pamela St. Louis, Karen Slattery, Danielle Duquette +12 more

Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer

Science Translational Medicine(2023)10.1126/scitranslmed.ade5855

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42 citations

Christi A Wisniewski, Choua Xiong, Peter Chhoy, Hira Lal Goel, Ayush Kumar +11 more

Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response

Science Advances(2023)10.1126/sciadv.ade9488

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25 citations

Minglin Ma, Atieh Sadraei, Hok Hei Tam, Shady Farah, Jennifer Hollister‐Lock +14 more

Simultaneous evaluation of treatment efficacy and toxicity for bispecific T‐cell engager therapeutics in a humanized mouse model

The FASEB Journal(2023)10.1096/fj.202300040r

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19 citations

Jing Jiao, Kyle Draheim, Guoxiang Yang, Hongyuan Yang, Li‐Chin Yao +11 more

CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-0433

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23 citations

Magali de Sauvage, Jane Chuprin, Emily Sullivan, Mohini Singh, Consuelo Torrini +8 more

NOD-scid IL2rγnull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity

Journal of Leukocyte Biology(2023)10.1093/jleuko/qiac020

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10 citations

Leonard D. Shultz, Lisa Burzenski, Dale L. Greiner, Michael A. Brehm, Ken‐Edwin Aryee

Generation and molecular characterization of human pluripotent stem cell-derived pharyngeal foregut endoderm

Developmental Cell(2023)10.1016/j.devcel.2023.08.024

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9 citations

Macrina Lobo, Ryan M. Genga, Ryan G. Abramowitz, Krishna Mohan Parsi, Jiang Min +8 more

Generation of the NeoThy mouse model for human immune system studies

Lab Animal(2023)10.1038/s41684-023-01196-z

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8 citations

Liupei Huang, Lydia Murphy, Jayalaxmi Suresh Babu, Cross Matthew Daffada, W. John Haynes +5 more

I-Ag7 β56/57 polymorphisms regulate non-cognate negative selection to CD4+ T cell orchestrators of type 1 diabetes

Nature Immunology(2023)10.1038/s41590-023-01441-0

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15 citations

Sarah B. Cleveland, Michael A. Brehm, Dale L. Greiner, Priya G. Huseby, Eric S. Huseby +1 more

Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies

Life Science Alliance(2023)10.26508/lsa.202101355

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11 citations

Cliff I. Oduor, Catherine S. Forconi, Viriato M’Bana, Courtney S. Bly, Rachel M. Gerstein +8 more

Physical activity regulates the immune response to breast cancer by a hematopoietic stem cell-autonomous mechanism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.30.560299

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2 citations

Katherine M. Hayes, Amanda Tutto, Amruta Samant, Lindsay M Ferreira, Tammy Nguyen +3 more

A human immune/muscle xenograft model of FSHD muscle pathology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.17.567590

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2 citations

Jing Yan, Lisa Burzenski, Jamie Kady, Leonard D. Shultz, Michael A. Brehm +2 more

Human Bone Marrow Adipose Tissue is a Hematopoietic Niche for Leptin-Driven Monopoiesis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.29.555167

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1 citations

Amruta Samant, Anand Desai, Tiffany DeSouza, Haley Cirka, Mai Ceesay +14 more

Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead

Nature Reviews Endocrinology(2024)10.1038/s41574-024-01029-0

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82 citations

Gregory S. Korbutt, Alice A. Tomei, Andrés J. Garcı́a, Andrew R. Pepper, Cherie L. Stabler +25 more

Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages

mBio(2024)10.1128/mbio.00454-24

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14 citations

Larissa A. Singletary, Fermin E. Guerra, Joyce E. Karlinsey, Stephen J. Libby, Sarah L. Jaslow +8 more

Neuropilin-2–expressing breast cancer cells mitigate radiation-induced oxidative stress through nitric oxide signaling

Journal of Clinical Investigation(2024)10.1172/jci181368

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12 citations

Hira Lal Goel, Christi A Wisniewski, T. Wang, Yansong Geng, Mengdie Wang +10 more

The co-receptor Neuropilin-1 enhances proliferation in inv(16) acute myeloid leukemia via VEGF signaling

Leukemia(2024)10.1038/s41375-024-02471-9

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8 citations

Mohd Hafiz Ahmad, Roger Mulet‐Lazaro, Mayumi Sugita, Rui Li, Kai Hu +9 more

IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas

Journal of Experimental & Clinical Cancer Research(2024)10.1186/s13046-024-03187-5

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7 citations

Karthik Dhatchinamoorthy, Laura Orellano-Ariza, Lydia Masako Ferreira, Michael A. Brehm, Kenneth L. Rock +1 more

IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas

Research Square(2024)10.21203/rs.3.rs-4997954/v1

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0DataRank · unranked

0 citations

Karthik Dhatchinamoorthy, Laura Orellano-Ariza, Lindsay M Ferreira, Michael A. Brehm, Kenneth L. Rock +1 more

Partial remission of type 1 diabetes: Do immunometabolic events define the honeymoon period?

Diabetes Obesity and Metabolism(2025)10.1111/dom.16480

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0DataRank · unranked

7 citations

Clive Wasserfall, Michael A. Brehm, Michael D. Karlstad, J. Jason Collier

Closing the Gap Between Vision and Victory in Type 1 Diabetes: The NIDDK Human Islet Research Network (HIRN) Initiative

Diabetes(2025)10.2337/db25-0097

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2 citations

Ashutosh Agarwal, Juan R. Alvarez‐Dominguez, Rafael Arrojo e Drigo, Mark A. Atkinson, Michael A. Brehm +10 more

Transplantation of human kidney organoids elicited a robust allogeneic response in a humanized mouse model

Kidney International(2025)10.1016/j.kint.2025.02.027

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1 citations

John Y. Choi, Jamie Kady, Marina de Cos, Jenny Wong, Emily King +21 more

Innovations, challenges, and minimal information for standardization of humanized mice

EMBO Molecular Medicine(2020)10.15252/emmm.201708662

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0DataRank · unranked

138 citations

Christian Münz, Jan Jacob Schuringa, Karl‐Dimiter Bissig, Brian W. Soper, Terrence Meeham +18 more

Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model

Journal of Pharmaceutical Sciences(2025)10.1016/j.xphs.2025.103964

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0DataRank · unranked

0 citations

Lisa Burzenski, Michael A. Brehm, Dale L. Greiner, Sathy V. Balu‐Iyer, Leonard D. Shultz +1 more