Siddharthan Chandran

Also affiliated with Edinburgh Royal Infirmary, MRC Centre for Regenerative Medicine, UK Dementia Research Institute, University of Edinburgh

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 25 papers. Top paper: “Improving the translational hit of experimental treatments in multiple sclerosis”.

Improving the translational hit of experimental treatments in multiple sclerosis

Multiple Sclerosis Journal(2010)10.1177/1352458510379612

N/A

7.5DataRank · unranked

182 citations

Emily S Sena, Charles ffrench-Constant, Anna Williams, Siddharthan Chandran, Malcolm R Macleod +1 more

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Journal of Clinical Investigation(2020)10.1172/jci139741

N/A

4.5DataRank · unranked

259 citations

Jack Humphrey, Sarah Pickles, Anna‐Leigh Brown, Sarah E. Hill, Jennifer M. Kachergus +47 more

CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity

Alzheimer s & Dementia(2022)10.1002/alz.12760

N/A

0.895DataRank · unranked

28 citations

Haibo Wang, Arun Kumar Tharkeshwar, Julien Couthouis, Elke Braems, Pegah Masrori +25 more

Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

Cell(2022)10.1016/j.cell.2022.08.021

N/A

0.862DataRank · unranked

313 citations

Ryan Baumann, Xiaohui Gao, Myra Mendoza, Sneha Singh, Ilana Katz Sand +38 more

A framework for sharing of clinical and genetic data for precision medicine applications

Nature Medicine(2024)10.1038/s41591-024-03239-5

N/A

0.857DataRank · unranked

32 citations

Ulugbek K. Baymuradov, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach +63 more

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

Nature Communications(2022)10.1038/s41467-021-27702-w

N/A

0.819DataRank · unranked

234 citations

Sachin S. Tiwari, Rolando Xavier Aviles‐Reyes, Monique Hooley, David W. Hampton, Megan Torvell +26 more

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

Nature Communications(2023)10.1038/s41467-023-40937-z

N/A

0.786DataRank · unranked

188 citations

Nurun Fancy, Maria Weinert, Stergios Tsartsalis, Manuel Marzin, Robert C. J. Muirhead +45 more

Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease

Brain and Neuroscience Advances(2022)10.1177/23982128221086464

N/A

0.650DataRank · unranked

17 citations

Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie Rose +9 more

TDP-43 loss induces cryptic polyadenylation in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02050-w

N/A

0.593DataRank · unranked

23 citations

Anna‐Leigh Brown, Max Z. Y. J. Chien, Dario Dattilo, Puja R. Mehta, Francesca Mattedi +94 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

iScience(2021)10.1016/j.isci.2021.103221

N/A

0.593DataRank · unranked

51 citations

Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono +92 more

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns

Molecular Autism(2020)10.1186/s13229-020-00351-4

N/A

0.524DataRank · unranked

32 citations

Rakhi Pal, K. R. Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Nisha Raj, Krishna Kumar Samaga +11 more

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

Stem Cell Research(2020)10.1016/j.scr.2020.101851

N/A

0.457DataRank · unranked

20 citations

Lindsay Panther, Loren Ornelas, Chunyan Liu, Emilda Gomez, Raquel Martín‐Ibáñez +18 more

Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study

International Journal of Stroke(2021)10.1177/1747493020974282

N/A

0.425DataRank · unranked

16 citations

Angus B Gane, Laura Middleton, Brendan Sargent, Tom J. Moullaali, Mark Rodrigues +161 more

C9orf72 hexanucleotide repeat expansions impair microglial response in ALS

Nature Neuroscience(2025)10.1038/s41593-025-02075-1

N/A

0.396DataRank · unranked

13 citations

Baukje Bijnens, Laura Fumagalli, Kristofer Davie, Suresh Poovathingal, Tim Meese +17 more

Logistic Regression–Based Model Is More Efficient Than U-Net Model for Reliable Whole Brain Magnetic Resonance Imaging Segmentation

Topics in Magnetic Resonance Imaging(2022)10.1097/rmr.0000000000000296

N/A

0.373DataRank · unranked

11 citations

Rozanna Meijboom, Serhat V. Okar, Tianxia Wu, Prasanna Parvathaneni, Yair Mina +5 more

Myelin sheaths in the central nervous system can withstand damage and dynamically remodel

Science(2026)10.1126/science.adr4661

N/A

0.330DataRank · unranked

8 citations

Julia van de Korput, Philipp N. Braaker, Kieran P. Higgins, Niels R. C. Meijns, Katy L. H. Marshall-Phelps +20 more

Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10 + 16 mutation

Neuropathology and Applied Neurobiology(2024)10.1111/nan.13006

N/A

0.269DataRank · unranked

5 citations

Robert I. McGeachan, Jamie McQueen, Paul Baxter, Nathan Rockley, Hannah McAlister +11 more

Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10+16 mutation

medRxiv(2024)10.1101/2024.04.09.24305501

N/A

0.269DataRank · unranked

5 citations

Robert I. McGeachan, Jamie McQueen, Paul Baxter, Nathan Rockley, Hannah McAlister +11 more

Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

Efficacy and Mechanism Evaluation(2020)10.3310/eme07030

N/A

0DataRank · unranked

27 citations

Peter Connick, Richard Parker, Domenico Plantone, Anisha Doshi, Nevin John +23 more

Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis

Neuropathology and Applied Neurobiology(2022)10.1111/nan.12851

N/A

0DataRank · unranked

18 citations

G. Campbell, Arpan R. Mehta, Katie McGill, Alex Symonds, Sarah Al‐Azki +18 more

Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis

Acta Neuropathologica(2020)10.1007/s00401-020-02179-x

N/A

0DataRank · unranked

94 citations

G. Campbell, Marco A. Cañizares, Arpan R. Mehta, Angus B. Gane, Katie McGill +32 more

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature(2022)10.1038/s41586-022-04436-3

N/A

0DataRank · unranked

525 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee +90 more

Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.24.469829

N/A

0DataRank · unranked

0 citations

Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie Rose +9 more

Fatigue in early multiple sclerosis: MRI metrics of neuroinflammation, relapse and neurodegeneration

Brain Communications(2024)10.1093/braincomms/fcae278

N/A

0DataRank · unranked

6 citations

Peter Foley, Niall MacDougall, Yair Mina, Elizabeth N. York, Agniete Kampaite +13 more

CRISPR/Cas9 Screen in Human iPSC-Derived Cortical Neurons Identifies NEK6 as a Novel Disease Modifier of C9orf72 Poly (PR) Toxicity

SSRN Electronic Journal(2020)10.2139/ssrn.3753807

N/A

0DataRank · unranked

1 citations

Arun Kumar Tharkeshwar, Julien Couthouis, Elke Braems, Pegah Masrori, Yannan Fan +19 more