Darrel W. Stafford

University of North Carolina at Chapel Hill

NursingMedicinePharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Nucleotide sequence of a 5S ribosomal RNA gene in the sea urchin Lytechinus variegatus

UNC Libraries(2020)10.17615/bks1-q160

Top 100%

0DataRank

Top 100%0 citations

Darrel W. Stafford, Aidong Lu, Deborah A. Steege

Papers

Driven by 26 papers — median percentile 0. Top paper: “A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle”.

A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle

Blood(2020)10.1182/blood.2019004234

N/A

0DataRank · unranked

12 citations

Caihong Li, Da‐Yun Jin, Brian O. Ingram, Zhenyu Hao, Xue Bai +4 more

Conformational Transitions in the Membrane Scaffold Protein of Phospholipid Bilayer Nanodiscs

UNC Libraries(2020)10.17615/76m6-d929

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0DataRank · unranked

0 citations

John R. Engen, Kasper D. Rand, Darrel W. Stafford, James W. Jorgenson, Christine M. Hebling +1 more

Human Vitamin K Epoxide Reductase and Its Bacterial Homologue Have Different Membrane Topologies and Reaction Mechanisms

UNC Libraries(2020)10.17615/2h3k-t115

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0DataRank · unranked

0 citations

Darrel W. Stafford, Da Yun Jin, Jian Ke Tie

A Conformational Investigation of Propeptide Binding to the Integral Membrane Protein γ-Glutamyl Carboxylase Using Nanodisc Hydrogen Exchange Mass Spectrometry

Figshare(2020)10.17615/krn5-w035

N/A

0DataRank · unranked

0 citations

Darrel W. Stafford, Christine H. Parker, John R. Engen, Kasper D. Rand, Christopher R. Morgan +1 more

Employing a Gain-of-Function Factor IX Variant R338L to Advance the Efficacy and Safety of Hemophilia B Human Gene Therapy: Preclinical Evaluation Supporting an Ongoing Adeno-Associated Virus Clinical Trial

UNC Libraries(2020)10.17615/fzyc-s786

N/A

0DataRank · unranked

0 citations

Tong Gui, Scott McPhee, Carmen J. Booth, Junjiang Sun, Tal Kafri +11 more

Nucleotide sequence of a 5S ribosomal RNA gene in the sea urchin Lytechinus variegatus

UNC Libraries(2020)10.17615/bks1-q160

Top 100%

0DataRank

Top 100%0 citations

Darrel W. Stafford, Aidong Lu, Deborah A. Steege

Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry

Figshare(2020)10.17615/1tp2-h420

N/A

0DataRank · unranked

0 citations

Kasper D. Rand, Christine M. Hebling, Christopher R. Morgan, Darrel W. Stafford, John R. Engen +1 more

Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions

UNC Libraries(2020)10.17615/395r-b130

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0DataRank · unranked

0 citations

Jian‐Ke Tie, Darrel W. Stafford, Balaji Chandra Sekhar Sinhadri, Da‐Yun Jin

Identification of the N-Linked Glycosylation Sites of Vitamin K-Dependent Carboxylase and Effect of Glycosylation on Carboxylase Function †

UNC Libraries(2020)10.17615/c585-qr41

N/A

0DataRank · unranked

0 citations

Mei-Yan Zheng, Jian‐Ke Tie, Darrel W. Stafford, R. Marshall Pope, David L. Straight

Modeling Zymogen Protein C

UNC Libraries(2020)10.17615/qcp3-r552

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0DataRank · unranked

0 citations

C. K. Foley, Lee G. Pedersen, Charles T. Esmon, Thomas A. Darden, Timothy Mather +2 more

Conserved Loop Cysteines of Vitamin K Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Are Involved in Its Active Site Regeneration

UNC Libraries(2020)10.17615/q0bj-v948

N/A

0DataRank · unranked

0 citations

Darrel W. Stafford, Da Yun Jin, Jian Ke Tie

Effect of Vitamin K-dependent Protein Precursor Propeptide, Vitamin K Hydroquinone, and Glutamate Substrate Binding on the Structure and Function of γ-Glutamyl Carboxylase

UNC Libraries(2020)10.17615/tc0x-j014

N/A

0DataRank · unranked

0 citations

Vasantha P. Mutucumarana, Darrel W. Stafford, James W. Jorgenson, Shannon L. Higgins-Gruber, Pen Jen Lin +1 more

Transmembrane Domain Interactions and Residue Proline 378 Are Essential for Proper Structure, Especially Disulfide Bond Formation, in the Human Vitamin K-Dependent γ-Glutamyl Carboxylase †

UNC Libraries(2020)10.17615/ntqs-k459

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0DataRank · unranked

0 citations

Kuang-Ling N. Hsiao, L. Perera, Darrel W. Stafford, Jian‐Ke Tie, David L. Straight +1 more

Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K‐dependent carboxylation

FEBS Journal(2021)10.1111/febs.16291

N/A

0DataRank · unranked

7 citations

Natsuko Furukawa, Da‐Yun Jin, Yizhou Liu, Darrel W. Stafford, Craig M. Williams +3 more

The Propeptides of the Vitamin K-dependent Proteins Possess Different Affinities for the Vitamin K-dependent Carboxylase

UNC Libraries(2021)10.17615/k2dz-a910

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0DataRank · unranked

0 citations

Thomas B. Stanley, Da Yun Jin, Darrel W. Stafford, Pen Jen Lin

Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties.

UNC Libraries(2021)10.17615/rsc6-by68

N/A

0DataRank · unranked

4 citations

Darrel W. Stafford, MJ Rabiet, BC Furie, DL Diuguid, CK Kasper +3 more

Evaluation of warfarin resistance using transcription activator-like effector nucleases-mediated vitamin K epoxide reductase knockout HEK293 cells

UNC Libraries(2021)10.17615/m14a-vw97

N/A

0DataRank · unranked

3 citations

Da-Yun Jin, Darrel W. Stafford, Jian‐Ke Tie, Kevin Tie

Localization of the human tissue factor recognition determinant of human factor VIIa

UNC Libraries(2021)10.17615/vnwd-qb54

N/A

0DataRank · unranked

3 citations

Kenneth J. Smith, Darrel W. Stafford, J R Toomey

The Propeptide Binding Site of the Bovine γ-Glutamyl Carboxylase

UNC Libraries(2021)10.17615/qy3b-8606

N/A

0DataRank · unranked

0 citations

Scott Geromanos, Darrel W. Stafford, Vasantha P. Mutucumarana, Sheue Mei Wu

Human Factor IX Binds to Specific Sites on the Collagenous Domain of Collagen IV

UNC Libraries(2021)10.17615/vb2w-jq45

N/A

0DataRank · unranked

0 citations

Dorothy A. Erie, Alisa S. Wolberg, Darrel W. Stafford

Expression and Characterization of the Naturally Occurring Mutation L394R in Human γ-Glutamyl Carboxylase

UNC Libraries(2021)10.17615/rfj3-5n12

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0DataRank · unranked

0 citations

Jesús Solera, Darrel W. Stafford, Vasantha P. Mutucumarana, Da-Yun Jin, Sheue Mei Wu +3 more

Membrane Topology Mapping of Vitamin K Epoxide Reductase by in Vitro Translation/Cotranslocation

UNC Libraries(2021)10.17615/knz2-4r49

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0DataRank · unranked

0 citations

Christopher V. Nicchitta, Jian Ke Tie, Darrel W. Stafford, Gunnar von Heijne

Binding of the Factor IX γ-Carboxyglutamic Acid Domain to the Vitamin K-dependent γ-Glutamyl Carboxylase Active Site Induces an Allosteric Effect That May Ensure Processive Carboxylation and Regulate the Release of Carboxylated Product

UNC Libraries(2021)10.17615/4k0c-bc42

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0DataRank · unranked

0 citations

David L. Straight, Darrel W. Stafford, Pen Jen Lin

A genome-wide CRISPR-Cas9 knockout screen reveals FSP1 as warfarin-resistant vitamin K reductase

Research Square(2022)10.21203/rs.3.rs-2039668/v1

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0DataRank · unranked

2 citations

Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford +2 more

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

Nature Communications(2023)10.1038/s41467-023-36446-8

N/A

0DataRank · unranked

71 citations

Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford +2 more

Molecular insights into the comorbidity of vitamin K-dependent clotting factor deficiency and chondrodysplasia punctata

Journal of Thrombosis and Haemostasis(2025)10.1016/j.jtha.2025.08.011

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0DataRank · unranked

0 citations

Xuejie Chen, Mengying Wang, Xiaofeng Qi, Darrel W. Stafford, Sara Lewis +4 more

Darrel W. Stafford

Indexed papers

Top data-sharing exemplar

Papers