Lacey E. Dobrolecki

Also affiliated with NĒRx BioSciences (United States), Children's Cancer Center

MedicineComputer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

8.2Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Nature Cancer(2022)10.1038/s43018-022-00337-6

Top 6%

3.9DataRank

Top 6%400 citations

Maihi Fujita, Andrew Butterfield, Sandra D. Scherer, Matthew H. Bailey, Zhengtao Chu +37 more

Papers

Driven by 37 papers — median percentile 69. Top paper: “A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology”.

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Nature Cancer(2022)10.1038/s43018-022-00337-6

Top 6%

3.9DataRank

Top 6%400 citations

Maihi Fujita, Andrew Butterfield, Sandra D. Scherer, Matthew H. Bailey, Zhengtao Chu +37 more

Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment

Nature Communications(2021)10.1038/s41467-021-25177-3

Top 8%

2.7DataRank

Top 8%109 citations

Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl +94 more

Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0200

N/A

2.5DataRank · unranked

140 citations

Eric J. Jaehnig, Karsten Krug, Jonathan T. Lei, Erik J. Bergstrom, Beom-Jun Kim +34 more

The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer

Nature Communications(2024)10.1038/s41467-024-45132-2

N/A

0.988DataRank · unranked

35 citations

Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey E. Dobrolecki +19 more

Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach

iScience(2022)10.1016/j.isci.2022.105799

N/A

0.830DataRank · unranked

35 citations

Lacey E. Dobrolecki, Lillian Ashmore, Alaina Lewis, Christina Sallas, Ramakrishnan Rajaram Srinivasan +25 more

Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer

Cell(2021)10.1016/j.cell.2020.12.031

N/A

0.814DataRank · unranked

227 citations

Jarey H. Wang, Fade Gong, William Wu, Nicholas J. Neill, Ik Sun Kim +32 more

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

Nature(2022)10.1038/s41586-022-04758-2

N/A

0.807DataRank · unranked

216 citations

Patricia Altea‐Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano +46 more

PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery

NAR Cancer(2022)10.1093/narcan/zcac014

Top 31%

0.652DataRank

Top 31%22 citations

Michael W. Lloyd, Jeffrey W. Grover, Nan Xiao, Sara Seepo, Sai Lakshmi Subramanian +95 more

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

UNC Libraries(2020)10.17615/43yk-w772

Top 31%

0.649DataRank

Top 31%17 citations

Qing Lai, Pavel Zuloaga, Amber M. Froehlich, Edward S. Chen, Jian Huang +24 more

RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer

EMBO Molecular Medicine(2023)10.15252/emmm.202216715

N/A

0.644DataRank · unranked

21 citations

Eva M. Trinidad, Gema Pérez-Chacón, Mansour Alsaleem, María Jiménez, María José Jiménez‐Santos +21 more

IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer

Cell(2024)10.1016/j.cell.2024.09.032

N/A

0.621DataRank · unranked

62 citations

Fanglue Peng, Qin Luo, Yao Ding, Fei Yuan, Liting Zheng +43 more

A novel treatment strategy utilizing panobinostat for high-risk and treatment-refractory hepatoblastoma

Journal of Hepatology(2024)10.1016/j.jhep.2024.01.003

N/A

0.515DataRank · unranked

30 citations

Roma H. Patel, Kalyani R. Patel, Andrew Badachhape, Richard S. Whitlock, Rohit Srivastava +23 more

PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101326

N/A

0.510DataRank · unranked

29 citations

Lacey E. Dobrolecki, Christina Sallas, Xudong Zhang, Travis Kerr, Deepa Bisht +19 more

Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer

Cancer Research(2021)10.1158/0008-5472.can-21-1256

N/A

0.483DataRank · unranked

24 citations

Meenakshi Anurag, Jonathan T. Lei, Beom‐Jun Kim, Purba Singh, Sinem Şeker +16 more

Immunologically “cold” triple negative breast cancers engraft at a higher rate in patient derived xenografts

npj Breast Cancer(2022)10.1038/s41523-022-00476-0

N/A

0.449DataRank · unranked

19 citations

Lacey E. Dobrolecki, Emily L. LaPlante, Ramakrishnan Rajaram Srinivasan, Matthew H. Bailey, Alana L. Welm +4 more

Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials

Tomography(2023)10.3390/tomography9020053

N/A

0.373DataRank · unranked

11 citations

Cristian T. Badea, Thomas L. Chenevert, Heike E. Daldrup‐Link, Li Ding, Lacey E. Dobrolecki +20 more

Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.101941

N/A

0.373DataRank · unranked

11 citations

K.H. Jung, Dongya Jia, Sukjin Yang, Kuldeep S. Attri, Songyeon Ahn +21 more

Toward Practical Integration of Omic and Imaging Data in Co-Clinical Trials

Tomography(2023)10.3390/tomography9020066

N/A

0.269DataRank · unranked

5 citations

Heidi Dowst, Julie C. DiCarlo, Lacey E. Dobrolecki, Anadulce Hernández-Herrera, David A. Hormuth +13 more

A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis

Cancer Research(2024)10.1158/0008-5472.can-23-1349

Top 62%

0.222DataRank

Top 62%3 citations

Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +49 more

ZP4: A novel target for CAR-T cell therapy in triple negative breast cancer

Molecular Therapy(2025)10.1016/j.ymthe.2025.02.029

N/A

0.208DataRank · unranked

3 citations

Jonathan T. Lei, Xinpei Yi, Diego F. Chamorro, Paul Shafer, Ahmed Z. Gad +7 more

Integrative Proteogenomics and Forward Genetics Reveal a Novel Mitotic Vulnerability in Triple-Negative Breast Cancer

Cancer Discovery(2025)10.1158/2159-8290.cd-23-1173

N/A

0.208DataRank · unranked

3 citations

Shankha Satpathy, Karsten Krug, Jitendra K. Meena, Nivetha Ramesh Babu, Cheyenne Calderon +51 more

Proteogenomic characterization unveils biomarkers associated with chemoresistance in muscle-invasive bladder cancer

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102255

N/A

0.104DataRank · unranked

1 citations

Yongchao Dou, Meggie N. Young, Alexander B. Saltzman, Meenakshi Anurag, Jonathan T. Lei +20 more

A Network Approach to Identify Biomarkers of Differential Chemotherapy Response Using Patient-Derived Xenografts of Triple-Negative Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.20.457116

N/A

0DataRank · unranked

5 citations

Lacey E. Dobrolecki, Lillian Ashmore, Alaina Lewis, Christina Sallas, Ramakrishnan Rajaram +19 more

A breast cancer patient-derived xenograft and organoid platform for drug discovery and precision oncology

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.28.433268

N/A

0DataRank · unranked

20 citations

Maihi Fujita, Andrew Butterfield, Sandra D. Scherer, Matthew H. Bailey, Zhengtao Chu +37 more

Three-dimensional electron microscopy uncovers mitochondrial network remodeling in residual triple negative breast cancer persisting after conventional chemotherapy treatments

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.09.611245

N/A

0DataRank · unranked

2 citations

Heather K. Beasley, Benjamin Rodriguez, Audra Lane, Steven W. Wall, Andrea G. Marshall +20 more

Co-Targeting BCL-xL with MCL-1 Induces Lethal Mitochondrial Dysfunction in Diffuse Mesothelioma

Molecular Cancer Therapeutics(2025)10.1158/1535-7163.mct-24-0873

N/A

0DataRank · unranked

3 citations

Cristian G. Medina, Deborah R. Surman, Lacey E. Dobrolecki, Monica Vilchis, Maheshwari Ramineni +10 more

Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity

Cancer Research(2025)10.1158/0008-5472.can-23-4022

N/A

0DataRank · unranked

2 citations

Ping Gong, John D. Landua, Ramakrishnan Rajaram Srinivasan, Abhinaya Ganesan, Lacey E. Dobrolecki +8 more

In Vivo Modeling of Human Breast Cancer Using Cell Line and Patient-Derived Xenografts

Journal of Mammary Gland Biology and Neoplasia(2022)10.1007/s10911-022-09520-y

N/A

0DataRank · unranked

34 citations

Lacey E. Dobrolecki, Hugo Villanueva, Andrew G. Sikora, Michael T. Lewis, Eric P. Souto

U-Net Model Weights for TEM Mitochondria Segmentation in Triple Negative Breast Cancer

Zenodo (CERN European Organization for Nuclear Research)(2025)10.5281/zenodo.19665008

N/A

0DataRank · unranked

0 citations

Mokryun L. Baek, Mariah J. Berner, Alexander Zhurkevich, Antentor Hinton, Matthew D. Meyer +5 more

Poziotinib Inhibits HER2-Mutant–Driven Therapeutic Resistance and Multiorgan Metastasis in Breast Cancer

Cancer Research(2022)10.1158/0008-5472.can-21-3106

N/A

0DataRank · unranked

17 citations

Ching Hui Chen, Junkai Wang, Ahmad Bin Salam, Lacey E. Dobrolecki, Alaina Lewis +9 more

XDec Simplex Map of Breast Cancer Cell States Enables Precise Modeling and Targeting of Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.06.498858

N/A

0DataRank · unranked

3 citations

Varduhi Petrosyan, Emily L. LaPlante, Lacey E. Dobrolecki, Michael T. Lewis, Aleksandar Milosavljevic +1 more

A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.26.512745

Top 100%

0DataRank

Top 100%0 citations

X. Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +45 more

Specific BRCA and immune configurations determine optimal response to platinum-based chemotherapy in triple negative breast and ovarian carcinomas

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.19.456799

N/A

0DataRank · unranked

0 citations

Kalyan Banda, Pooja Kumar, Robert F. Straub, Lacey E. Dobrolecki, Isabel V. Rodriguez +10 more

Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.16.448722

N/A

0DataRank · unranked

0 citations

Elena B. Kabotyanski, Elizabeth Villegas, Jonathan H. Shepherd, Deanna Acosta, Clark Hamor +11 more

Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer

Cancer Research(2023)10.1158/0008-5472.can-22-3484

N/A

0DataRank · unranked

12 citations

Beom-Jun Kim, Meenakshi Anurag, Jonathan T. Lei, Meggie N. Young, Matthew V. Holt +11 more

Deconvolution of cancer cell states by the XDec-SM method

PLoS Computational Biology(2023)10.1371/journal.pcbi.1011365

N/A

0DataRank · unranked

1 citations

Varduhi Petrosyan, Emily L. LaPlante, Lacey E. Dobrolecki, Michael T. Lewis, Aleksandar Milosavljevic +1 more

The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.15.557958

N/A

0DataRank · unranked

0 citations

Ping Gong, John D. Landua, R. Rajaram Srinivasan, Abhinaya Ganesan, Lacey E. Dobrolecki +8 more

Lacey E. Dobrolecki

Indexed papers

Top data-sharing exemplar

Papers