Stefan Laufer

Also affiliated with Bernstein Center for Computational Neuroscience Tübingen, University Hospital Ulm, Center for Discovery, Guided Therapeutics (United States), University of Tübingen

Biochemistry, Genetics and Molecular BiologyChemistryMaterials ScienceComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites”.

Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00848

N/A

1.3DataRank · unranked

45 citations

David E. Heppner, Ciric To, Marcel Günther, Bo Hee Shin, Jaimin K. Rana +13 more

Controlling the Covalent Reactivity of a Kinase Inhibitor with Light

Angewandte Chemie International Edition(2021)10.1002/anie.202103767

N/A

0.578DataRank · unranked

46 citations

A. Chaikuad, Benedict‐Tilman Berger, Katharina Bauer, Pierre Koch, Stefan Laufer +3 more

HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115935

N/A

0.360DataRank · unranked

10 citations

Larissa Costa de Almeida, Marina Candido Primi, Jorge Antonio Elias Godoy Carlos, Claudia Ruiz, Thales Kronenberger +14 more

Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors

ChemRxiv(2023)10.26434/chemrxiv-2023-cs3xn-v2

N/A

0.208DataRank · unranked

3 citations

Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner +15 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

ChemRxiv(2021)10.26434/chemrxiv.14601264

N/A

0DataRank · unranked

0 citations

André da Silva Santiago, Caio dos Reis, Jéssica E. Takarada, Priscila Mezzomo, Katlin B. Massirer +9 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01165

N/A

0DataRank · unranked

27 citations

André da Silva Santiago, Martin P. Schwalm, Zexi Hu, C.V. dos Reis, Jéssica E. Takarada +11 more

Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448)

ChemRxiv(2022)10.26434/chemrxiv-2022-5m8h5-v2

N/A

0DataRank · unranked

3 citations

Tyler S. Beyett, Tatiana Shaurova, Calvin Pham, Florian Wittlinger, Ilse K. Schaeffner +6 more

Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448)

ChemRxiv(2022)10.26434/chemrxiv-2022-5m8h5

N/A

0DataRank · unranked

0 citations

Tyler S. Beyett, Tatiana Shaurova, Calvin Pham, Florian Wittlinger, Ilse K. Schaeffner +6 more

Structural elements that enable specificity for mutant EGFR kinase domains with next-generation small-molecule inhibitors

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.03.013

N/A

0DataRank · unranked

8 citations

Florian Wittlinger, Tyler S. Beyett, Michael J. Eck, Stefan Laufer, David E. Heppner +1 more

Examining molecular factors of inactive versus active bivalent EGFR inhibitors: A missing link in fragment-based drug design.

ChemRxiv(2023)10.26434/chemrxiv-2023-cs3xn

N/A

0DataRank · unranked

3 citations

Blessing C. Ogboo, Calvin D. Pham, Ilse K. Schaeffner, Surbhi P. Chitnis, Tahereh Damghani +12 more

Pitfalls and considerations in determining the potency and mutant selectivity of covalent epidermal growth factor receptor inhibitors

ChemRxiv(2023)10.26434/chemrxiv-2023-tkqqk

N/A

0DataRank · unranked

2 citations

Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer +3 more

The origin of potency and mutant-selective inhibition by bivalent ATP-allosteric EGFR inhibitors

ChemRxiv(2023)10.26434/chemrxiv-2023-zzfc3

N/A

0DataRank · unranked

2 citations

Surbhi P. Chitnis, Calvin D Pham, Tahereh Damghani, Ilse K. Schaeffner, Matthew Q. Deng +13 more

Structural elements that enable specificity for mutant EGFR kinase domains with next-generation small-molecule inhibitors.

ChemRxiv(2023)10.26434/chemrxiv-2023-v522v

N/A

0DataRank · unranked

0 citations

Florian Wittlinger, Tyler S. Beyett, Michael J. Eck, Stefan Laufer, David E. Heppner +1 more

Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors

Research Square(2023)10.21203/rs.3.rs-3286949/v1

N/A

0DataRank · unranked

0 citations

Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin Pham +15 more

Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors

Communications Chemistry(2024)10.1038/s42004-024-01108-3

N/A

0DataRank · unranked

24 citations

Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner +15 more

Tilting the Scales toward EGFR Mutant Selectivity: Expanding the Scope of Bivalent “Type V” Kinase Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02311

N/A

0DataRank · unranked

8 citations

Surbhi P. Chitnis, Calvin D. Pham, Tahereh Damghani, Kishan B. Patel, Mareike Möllers +17 more

Structure–Activity Relationships of Inactive‐Conformation Binding EGFR Inhibitors: Linking the ATP and Allosteric Pockets

Archiv der Pharmazie(2025)10.1002/ardp.70027

N/A

0DataRank · unranked

5 citations

Florian Wittlinger, Mareike Möllers, Tyler J. Hartman, Marcel Günther, Michael J. Eck +3 more

Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01520

N/A

0DataRank · unranked

4 citations

Jyoti Vishwakarma, Katharina Sylvester, Nobuyo Higashi‐Kuwata, Agnieszka Dąbrowska, Renee Delgado +16 more

Molecular Design of a “Two-in-One” Orthosteric-Allosteric Chimeric Mutant Selective EGFR Inhibitor

ChemRxiv(2020)10.26434/chemrxiv.13416452

N/A

0DataRank · unranked

1 citations

david heppner, Ciric To, Marcel C. Guenther, Bo Hee Shin, Jaimin K Rana +6 more

Structure-activity relationships of inactive-conformation binding EGFR inhibitors: Linking the ATP and allosteric pockets

ChemRxiv(2025)10.26434/chemrxiv-2025-2cdjb

N/A

0DataRank · unranked

0 citations

Florian Wittlinger, Mareike Möllers, Tyler J. Hartman, Marcel Günther, Michael J. Eck +3 more

Molecular Design of a “Two-in-One” Orthosteric-Allosteric Chimeric Mutant Selective EGFR Inhibitor

(2020)10.26434/chemrxiv.13416452.v1

N/A

0DataRank · unranked

0 citations

David E. Heppner, Ciric To, Marcel C. Guenther, Bo Hee Shin, Jaimin K Rana +6 more

Controlling the Covalent Reactivity of a Kinase Inhibitor with Light

Angewandte Chemie(2021)10.1002/ange.202103767

N/A

0DataRank · unranked

4 citations

A. Chaikuad, Benedict‐Tilman Berger, Katharina Bauer, Pierre Koch, Stefan Laufer +3 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

ChemRxiv(2021)10.26434/chemrxiv.14601264.v1

N/A

0DataRank · unranked

2 citations

André da Silva Santiago, Caio dos Reis, Jéssica E. Takarada, Priscila Mezzomo, Katlin B. Massirer +9 more