🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Xushen Xiong

Broad Institute

ORCID: 0000-0001-7090-7503

Also affiliated with Sir Run Run Shaw Hospital, Second Affiliated Hospital of Zhejiang University, Massachusetts Institute of Technology, Zhejiang University

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile
0.961Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease

Nature Genetics(2023)10.1038/s41588-023-01509-5
Top 21%
0.961DataRank
Top 21%37 citations

Xushen Xiong, Yongjin Park, Carles B. Adsera, Benjamin T. James, Na Sun +11 more

Papers

Driven by 11 papers — median percentile 79. Top paper: “Genetic drivers of m6A methylation in human brain, lung, heart and muscle”.

Genetic drivers of m6A methylation in human brain, lung, heart and muscle

Nature Genetics(2021)10.1038/s41588-021-00890-3
N/A
3.3DataRank · unranked
152 citations

Lei Hou, Yongjin P. Park, Benoit Molinie, Alvaro N. Barbeira, François Aguet +4 more

Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease

Nature Genetics(2023)10.1038/s41588-023-01509-5
Top 21%
0.961DataRank
Top 21%37 citations

Xushen Xiong, Yongjin Park, Carles B. Adsera, Benjamin T. James, Na Sun +11 more

Human microglial state dynamics in Alzheimer’s disease progression

Cell(2023)10.1016/j.cell.2023.08.037
N/A
0.893DataRank · unranked
384 citations

Matheus B. Victor, Yongjin P. Park, Xushen Xiong, Aine Ni Scannail, Gloria Suella Menchaca +14 more

Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion

Cell(2023)10.1016/j.cell.2023.08.040
N/A
0.795DataRank · unranked
199 citations

Benjamin T. James, Carles B. Adsera, Yongjin P. Park, Kyriaki Galani, Matheus B. Victor +12 more

Crosstalk between epitranscriptomic and epigenomic modifications and its implication in human diseases

Cell Genomics(2024)10.1016/j.xgen.2024.100605
N/A
0.502DataRank · unranked
15 citations

Kexuan Chen, Qianchen Fang, Shaohui Shi, Jiuhong Nan, Jialin He +9 more

Deep learning prediction of ribosome profiling with Translatomer reveals translational regulation and interprets disease variants

Nature Machine Intelligence(2024)10.1038/s42256-024-00915-6
N/A
0.416DataRank · unranked
9 citations

Lei Xiong, Shaohui Shi, Chengyu Li, Kexuan Chen, Qianchen Fang +9 more

Context-dependent regulatory variants in Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.11.659973
N/A
0.171DataRank · unranked
2 citations

Yaxuan Liu, Ashley R. Brown, Heather H. Sestili, Easwaran Ramamurthy, Xushen Xiong +11 more

The tRNA Editing Complex ADAT2/3 Promotes Cancer Cell Growth and Codon-biased mRNA Translation

Journal of Molecular Biology(2025)10.1016/j.jmb.2025.169414
N/A
0DataRank · unranked
0 citations

Titi Rindi Antika, Qi Liu, Xushen Xiong, Raja Hussain Ali, Alejandro Gutiérrez +2 more

Deep learning modeling of ribosome profiling reveals regulatory underpinnings of translatome and interprets disease variants

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.26.582217
N/A
0DataRank · unranked
0 citations

Lei Xiong, Shaohui Shi, Chengyu Li, Kexuan Chen, Qianchen Fang +9 more

5. INTEGRATION OF GENETIC, EPIGENOMIC, AND PHENOTYPIC DATA ELUCIDATES ROLES OF CIRCULATING IMMUNE CELLS IN BIPOLAR DISORDER

European Neuropsychopharmacology(2023)10.1016/j.euroneuro.2023.08.116
N/A
0DataRank · unranked
0 citations

Yue Li, Xushen Xiong, Yongjin Park, Samuel Lenz, Amy Grayson +13 more

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Cell(2025)10.1016/j.cell.2025.06.031
N/A
0DataRank · unranked
38 citations

Shanshan Zhang, Benjamin T. James, Kyriaki Galani, Riley J. Mangan, Stuart B. Fass +27 more