Markus D. Siegelin

Columbia University Irving Medical Center

Also affiliated with Columbia University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 28 papers. Top paper: “Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis”.

Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis

Human Genetics(2020)10.1007/s00439-020-02188-6

N/A

2.1DataRank · unranked

32 citations

Loukas Argyriou, Francisco Martínez‐Azorín, Susanne Morlot, Gökhan Yiğit, Teresa M. Lee +19 more

Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-21-2857

N/A

1.1DataRank · unranked

31 citations

Enyuan Shang, Salveena Schiffgens, Consuelo Torrini, Chang Shu, Hasan Orhan Akman +6 more

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Cell(2022)10.1016/j.cell.2022.06.007

N/A

0.807DataRank · unranked

216 citations

Johannes C. Melms, Amit Dipak Amin, Yiping Wang, Lindsay Caprio, Alcida Karz +54 more

Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro

British Journal of Cancer(2024)10.1038/s41416-024-02608-8

N/A

0.511DataRank · unranked

13 citations

Annika Hajosch, Richard E. Kast, C Loehmann, Michal Hlaváč, Pamela Fischer‐Posovszky +7 more

Targeting cellular respiration as a therapeutic strategy in glioblastoma

Oncotarget(2023)10.18632/oncotarget.28424

N/A

0.416DataRank · unranked

15 citations

Trang Nguyen, Mike‐Andrew Westhoff, Georg Karpel‐Massler, Markus D. Siegelin, Enyuan Shang

OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma

JCI Insight(2024)10.1172/jci.insight.172565

N/A

0.415DataRank · unranked

9 citations

Consuelo Torrini, Enyuan Shang, Chang Shu, Jeong-Yeon Mun, Qiuqiang Gao +9 more

ONC201/TIC10 Is Empowered by 2-Deoxyglucose and Causes Metabolic Reprogramming in Medulloblastoma Cells in Vitro Independent of C-Myc Expression

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.734699

N/A

0.292DataRank · unranked

6 citations

Maximilian Pruss, Qiyu Cao, Mine Tanriover, Varun V. Prabhu, Joshua E. Allen +6 more

CDK12 regulates cellular metabolism to promote glioblastoma growth

JCI Insight(2025)10.1172/jci.insight.190780

N/A

0.165DataRank · unranked

2 citations

Chang Shu, Qiuqiang Gao, Zhe Zhu, Hasan O. Akman, Mike‐Andrew Westhoff +3 more

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Nature Communications(2023)10.1038/s41467-023-36630-w

N/A

0DataRank · unranked

189 citations

Dominique Higgins, Angeliki Mela, Matei A. Banu, Athanassios Dovas, Fereshteh Zandkarimi +20 more

Targeting Transcription Factors ATF5, CEBPB and CEBPD with Cell-Penetrating Peptides to Treat Brain and Other Cancers

Cells(2023)10.3390/cells12040581

N/A

0DataRank · unranked

25 citations

Qing Zhou, Markus D. Siegelin, James M. Angelastro, Lloyd A. Greene

A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.22.529581

N/A

0DataRank · unranked

3 citations

Athanassios Dovas, Michael Argenziano, Wenting Zhao, Henar Cuervo, Dominique Higgins +20 more

Data from Global Targeting of Subcellular Heat Shock Protein-90 Networks for Therapy of Glioblastoma

(2023)10.1158/1535-7163.c.6531876

N/A

0DataRank · unranked

0 citations

Janet Plescia, Christopher M. Raskett, Candace A. Gilbert, Alonzo H. Ross, Dario C. Altieri +1 more

Data from Global Targeting of Subcellular Heat Shock Protein-90 Networks for Therapy of Glioblastoma

(2023)10.1158/1535-7163.c.6531876.v1

N/A

0DataRank · unranked

0 citations

Janet Plescia, Christopher M. Raskett, Candace A. Gilbert, Alonzo H. Ross, Dario C. Altieri +1 more

Data from Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma

(2023)10.1158/1078-0432.c.6530823

N/A

0DataRank · unranked

0 citations

Enyuan Shang, Salveena Schiffgens, Consuelo Torrini, Chang Shu, Hasan O. Akman +6 more

Data from Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma

(2023)10.1158/1078-0432.c.6530823.v1

N/A

0DataRank · unranked

0 citations

Enyuan Shang, Salveena Schiffgens, Consuelo Torrini, Chang Shu, Hasan O. Akman +6 more

A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

The EMBO Journal(2024)10.1038/s44318-024-00176-4

N/A

0DataRank · unranked

26 citations

Athanassios Dovas, Michael Argenziano, Wenting Zhao, Colin Sperring, Henar Cuervo +25 more

Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator

Acta Neuropathologica(2024)10.1007/s00401-024-02755-5

N/A

0DataRank · unranked

10 citations

Matti Lam, Julie J. McInvale, Jason Mares, Sam Hyun Kwon, Nelson Humala +14 more

DPEP Inhibits Cancer Cell Glucose Uptake, Glycolysis and Survival by Upregulating Tumor Suppressor TXNIP

Cells(2024)10.3390/cells13121025

N/A

0DataRank · unranked

3 citations

Trang Nguyen, Jeong-Yeon Mun, Markus D. Siegelin, Lloyd A. Greene, Qing Zhou

DPEP Inhibits Cancer Cell Glucose Uptake, Glycolysis and Survival by Upregulating Tumor Suppressor TXNIP

Preprints.org(2024)10.20944/preprints202405.0846.v1

N/A

0DataRank · unranked

3 citations

Trang Nguyen, Jeong-Yeon Mun, Markus D. Siegelin, Lloyd A. Greene, Qing Zhou

HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models

Journal of Clinical Investigation(2020)10.1172/jci129049

N/A

0DataRank · unranked

210 citations

Yiru Zhang, Enyuan Shang, Chang Shu, Consuelo Torrini, Junfei Zhao +14 more

Targeting ATF5, CEBPB, and CEBPD with Cell-Penetrating Dpep Sensitizes Tumor Cells to NK-92MI Cell Cytotoxicity

Cells(2025)10.3390/cells14090667

N/A

0DataRank · unranked

0 citations

Markus D. Siegelin, Lloyd A. Greene, Qing Zhou

Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma

British Journal of Cancer(2020)10.1038/s41416-020-0759-0

N/A

0DataRank · unranked

54 citations

Annika Dwucet, Mine Tanriover, Michal Hlaváč, Richard E. Kast, Klaus‐Michael Debatin +6 more

Epigenetic Targeting of Mcl-1 Is Synthetically Lethal with Bcl-xL/Bcl-2 Inhibition in Model Systems of Glioblastoma

Cancers(2020)10.3390/cancers12082137

N/A

0DataRank · unranked

28 citations

Trang Nguyen, Chang Shu, Mike‐Andrew Westhoff, Georg Karpel‐Massler, Markus D. Siegelin +1 more

Metabolic Reprogramming by c-MET Inhibition as a Targetable Vulnerability in Glioblastoma

Oncoscience(2020)10.18632/oncoscience.498

N/A

0DataRank · unranked

2 citations

Enyuan Shang, Georg Karpel‐Massler, Markus D. Siegelin, Trang Nguyen

Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma

Nature Communications(2021)10.1038/s41467-021-25501-x

N/A

0DataRank · unranked

110 citations

Enyuan Shang, Chang Shu, Sung Soo Kim, Angeliki Mela, Nelson Humala +11 more

Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents

Cancers(2021)10.3390/cancers13102504

N/A

0DataRank · unranked

38 citations

Xiotian Sun, Nicolas Pasquier, Parvaneh Jefferson, Trang Nguyen, Markus D. Siegelin +3 more

Targeting super-enhancers reprograms glioblastoma central carbon metabolism

Oncotarget(2021)10.18632/oncotarget.27938

N/A

0DataRank · unranked

4 citations

Mike‐Andrew Westhoff, Georg Karpel‐Massler, Markus D. Siegelin, Trang Nguyen

RAB38 Facilitates Energy Metabolism and Counteracts Cell Death in Glioblastoma Cells

Cells(2021)10.3390/cells10071643

N/A

0DataRank · unranked

6 citations

Sierra J. Bates, Trang Nguyen, Markus D. Siegelin, Kevin A. Roth, Elena Bianchetti