Samuel Klein

Also affiliated with Jessa Hospital, Columbia University, Hasselt University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 64 papers. Top paper: “Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes”.

Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes

New England Journal of Medicine(2020)10.1056/nejmoa2003697

N/A

5.3DataRank · unranked

240 citations

Brandon D. Kayser, Jun Yoshino, Richard I. Stein, Dominic N. Reeds, J. Christopher Eagon +8 more

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women

Science(2021)10.1126/science.abe9985

N/A

4.8DataRank · unranked

419 citations

Jun Yoshino, Brandon D. Kayser, Gary J. Patti, Michael P. Franczyk, Kathryn F. Mills +6 more

Associations Among Adipose Tissue Immunology, Inflammation, Exosomes and Insulin Sensitivity in People With Obesity and Nonalcoholic Fatty Liver Disease

Gastroenterology(2021)10.1053/j.gastro.2021.05.008

N/A

3.6DataRank · unranked

158 citations

Dmitri Samovski, Gordon I. Smith, Vincenza Cifarelli, Sarah S. Farabi, Jun Yoshino +6 more

Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity

Journal of Clinical Investigation(2020)10.1172/jci141828

N/A

3.3DataRank · unranked

128 citations

Scott C. Beeman, Gordon I. Smith, Jun Yoshino, Darya Morozov, Joseph W. Beals +6 more

Influence of adiposity, insulin resistance, and intrahepatic triglyceride content on insulin kinetics

Journal of Clinical Investigation(2020)10.1172/jci136756

N/A

2.7DataRank · unranked

74 citations

David Polidori, Mihoko Yoshino, Monica L. Kearney, Bruce W. Patterson, Bettina Mittendorfer +2 more

Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity

Cell Metabolism(2024)10.1016/j.cmet.2024.03.002

N/A

2.3DataRank · unranked

128 citations

Gordon I. Smith, Hector H. Palacios, Sarah S. Farabi, Mihoko Yoshino, Jun Yoshino +12 more

The mitochondrial dicarboxylate carrier prevents hepatic lipotoxicity by inhibiting white adipocyte lipolysis

Journal of Hepatology(2021)10.1016/j.jhep.2021.03.006

N/A

2.0DataRank · unranked

61 citations

Shiuhwei Chen, Yingfeng Deng, Zhao V. Wang, Jan‐Bernd Funcke, Manasi Shah +7 more

β Cell function and plasma insulin clearance in people with obesity and different glycemic status

Journal of Clinical Investigation(2021)10.1172/jci154068

N/A

1.5DataRank · unranked

56 citations

Bruce W. Patterson, Gordon I. Smith, Mihoko Yoshino, Samuel Klein, Bettina Mittendorfer

Dietary weight loss-induced improvements in metabolic function are enhanced by exercise in people with obesity and prediabetes

Nature Metabolism(2023)10.1038/s42255-023-00829-4

N/A

1.5DataRank · unranked

55 citations

Brandon D. Kayser, Gordon I. Smith, George G. Schweitzer, Kyleigh Kirbach, Monica L. Kearney +6 more

Control of lipolysis by a population of oxytocinergic sympathetic neurons

Nature(2023)10.1038/s41586-023-06830-x

N/A

1.4DataRank · unranked

44 citations

Luhong Wang, Daqing Wang, Jingyi Chi, Zeran Lin, Gordon I. Smith +4 more

Human gut microbes associated with obesity

Nature(2006)10.1038/4441022a

N/A

1.4DataRank · unranked

8708 citations

Peter J. Turnbaugh, Samuel Klein, Jeffrey I. Gordon, Ruth E. Ley

The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice

Cell Metabolism(2022)10.1016/j.cmet.2022.09.019

N/A

1.0DataRank · unranked

30 citations

Peter M. Masschelin, Pradip Saha, Jessica B. Felix, Robert Sharp, Zeqin Lian +15 more

Why does obesity cause diabetes?

Cell Metabolism(2022)10.1016/j.cmet.2021.12.012

N/A

1.0DataRank · unranked

895 citations

Amalia Gastaldelli, Hannele Yki‐Järvinen, Philipp E. Scherer, Samuel Klein

Insulin Sensitivity and β-Cell Function During Early and Late Pregnancy in Women With and Without Gestational Diabetes Mellitus

Diabetes Care(2023)10.2337/dc22-1894

N/A

0.894DataRank · unranked

23 citations

Bruce W. Patterson, Debra Haire‐Joshu, Alison G. Cahill, W. Todd Cade, Richard I. Stein +2 more

Heterogeneity in insulin-stimulated glucose uptake among different muscle groups in healthy lean people and people with obesity

Diabetologia(2021)10.1007/s00125-021-05383-w

N/A

0.833DataRank · unranked

29 citations

Stephan van Vliet, Gretchen A. Meyer, Richard Laforest, Robert J. Gropler, Samuel Klein +2 more

Worksite-based intensive lifestyle therapy has profound cardiometabolic benefits in people with obesity and type 2 diabetes

Cell Metabolism(2022)10.1016/j.cmet.2022.08.012

N/A

0.777DataRank · unranked

25 citations

Jun Yoshino, Gordon I. Smith, Richard I. Stein, Adam J. Bittel, Daniel C. Bittel +9 more

Increased Adipose Tissue Fibrogenesis, Not Impaired Expandability, Is Associated With Nonalcoholic Fatty Liver Disease

Hepatology(2021)10.1002/hep.31822

N/A

0.598DataRank · unranked

53 citations

Gordon I. Smith, Mahalakshmi Shankaran, Anja Fuchs, George G. Schweitzer, Jun Yoshino +8 more

A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity

Cell Reports(2021)10.1016/j.celrep.2021.109301

N/A

0.596DataRank · unranked

52 citations

Susma Ghimire, Stephanie Bruggink, Kendra E. Miller, Savanna N. Weninger, Jason M. Kronenfeld +5 more

Effect of excessive gestational weight gain on insulin sensitivity and insulin kinetics in women with overweight/obesity

Obesity(2022)10.1002/oby.23533

N/A

0.595DataRank · unranked

16 citations

Bettina Mittendorfer, Bruce W. Patterson, Debra Haire‐Joshu, Alison G. Cahill, Richard I. Stein +5 more

Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes

Diabetes(2024)10.2337/db24-0083

N/A

0.585DataRank · unranked

15 citations

Mihoko Yoshino, Gordon I. Smith, Rafael Calais Gaspar, Mario Kahn, Dmitri Samovski +3 more

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

Cell(2022)10.1016/j.cell.2022.10.003

N/A

0.553DataRank · unranked

39 citations

Luiz H. M. Bozi, Yizhi Sun, Christopher L. Riley, Vivek M. Philip, Mandy Chen +41 more

Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis

Nature Communications(2021)10.1038/s41467-021-25025-4

N/A

0.538DataRank · unranked

35 citations

Na Li, Mingyang Huang, Mason Bartels, Sophie Dogné, Shangang Zhao +19 more

Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release

Cell Reports(2021)10.1016/j.celrep.2021.109298

N/A

0.529DataRank · unranked

33 citations

Susma Ghimire, Chelsea Hepler, Kendra E. Miller, Stephanie Bruggink, Kyle Kentch +6 more

Very-low-density lipoprotein triglyceride and free fatty acid plasma kinetics in women with high or low brown adipose tissue volume and overweight/obesity

Cell Reports Medicine(2024)10.1016/j.xcrm.2023.101370

N/A

0.502DataRank · unranked

13 citations

Jun Yoshino, R. Ramaswamy, Joseph Daniel Giardina, Richard Laforest, Richard L. Wahl +4 more

The role of brown adipose tissue in branched-chain amino acid clearance in people

iScience(2024)10.1016/j.isci.2024.110559

N/A

0.345DataRank · unranked

9 citations

Guobao Wang, Siqi Li, Vanessa Pellegrinelli, Abhijit J. Chaudhari, Anthony Ramirez +7 more

Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice

Journal of Clinical Investigation(2024)10.1172/jci169722

N/A

0.332DataRank · unranked

7 citations

Jason Singer, Daniel Ferguson, Trevor M. Shew, M. Katie Renkemeyer, Hector H. Palacios +15 more

Critical Evaluation of Indices Used to Assess β-Cell Function

Diabetes(2023)10.2337/db23-0613

N/A

0.292DataRank · unranked

6 citations

Han‐Chow E. Koh, Dominic N. Reeds, Bruce W. Patterson, Samuel Klein, Bettina Mittendorfer +1 more

Dorsal striatal response to taste is modified by obesity and insulin resistance

Obesity(2023)10.1002/oby.23799

N/A

0.284DataRank · unranked

4 citations

Bidhan Lamichhane, Gordon I. Smith, Amy Garner, Michael Wallendorf, Tamara Hershey +2 more

Plasma endotrophin levels correlate with insulin resistance in people with obesity

Journal of Clinical Investigation(2025)10.1172/jci190577

N/A

0.269DataRank · unranked

5 citations

Samuel Klein, Gordon I. Smith

N-acetylaspartate from fat cells regulates postprandial body temperature

Nature Metabolism(2025)10.1038/s42255-025-01334-6

N/A

0.269DataRank · unranked

5 citations

Pradip Saha, Evelyn Groot, Lin Tan, Robert Sharp, Elizabeth S Anaya +11 more

LIFE-Moms: effects of multicomponent lifestyle randomized control trial on physical activity during pregnancy in women with overweight and obesity

International Journal of Behavioral Nutrition and Physical Activity(2025)10.1186/s12966-025-01805-9

N/A

0.208DataRank · unranked

3 citations

Kimberly L. Drews, Jeremy Pomeroy, Sarah Kozey Keadle, S. Sonia Arteaga, Paul W. Franks +93 more

Combined α- and β-adrenergic receptor activation triggers thermogenesis by the futile creatine cycle

Research Square(2022)10.21203/rs.3.rs-1190032/v1

N/A

0.165DataRank · unranked

2 citations

Janane F. Rahbani, Charlotte Scholtes, Damien Lagarde, Mohammed F. Hussain, Anna Roesler +27 more

N-acetylaspartate from fat cells regulates postprandial body temperature

Research Square(2024)10.21203/rs.3.rs-3835159/v1

N/A

0.104DataRank · unranked

1 citations

Pradip Saha, Evelyn de Groot, Lin Tan, R. Sharp, Elizabeth S Anaya +11 more

The energy balance model of obesity: beyond calories in, calories out

American Journal of Clinical Nutrition(2022)10.1093/ajcn/nqac031

N/A

0DataRank · unranked

309 citations

I. Sadaf Farooqi, Jeffery M. Friedman, Samuel Klein, Ruth J. F. Loos, David J. Mangelsdorf +7 more

Accumulation of auranofin in white adipose tissues lowers leptin levels and exerts anti-diabetic effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.11.459899

N/A

0DataRank · unranked

0 citations

Peter M. Masschelin, Pradip Saha, Jessica B. Felix, Robert Sharp, Zeqin Lian +14 more

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.22.461414

N/A

0DataRank · unranked

3 citations

Manuel Gutiérrez‐Aguilar, Nicole K.H. Yiew, Andrew J. Lutkewitte, Jason Singer, Kyle S. McCommis +8 more

Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

JHEP Reports(2023)10.1016/j.jhepr.2023.100877

N/A

0DataRank · unranked

24 citations

Sabine Daemen, Joseph W. Beals, Marina Terekhova, Bin Yang, Christina Fu +14 more

Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility

Endocrinology(2021)10.1210/endocr/bqab006

N/A

0DataRank · unranked

23 citations

Nathan Qi, Kelly L. Stromsdorfer, Chengcheng Li, Shintaro Yamaguchi, Hiroshi Itoh +8 more

Cardio‐renal‐metabolic disease in primary care setting

Diabetes/Metabolism Research and Reviews(2023)10.1002/dmrr.3755

N/A

0DataRank · unranked

13 citations

Ebtesam Ba-Essa, Jason Baker, Avivit Cahn, Antonio Ceriello, Francesco Cosentino +18 more

Describing the Weight‐Reduced State: Physiology, Behavior, and Interventions

Obesity(2021)10.1002/oby.23086

N/A

0DataRank · unranked

111 citations

Kevin D. Hall, John M. Jakicic, Rudolph L. Leibel, Michael R. Lowe, Michael Rosenbaum +2 more

Heterogeneity in the effect of marked weight loss on metabolic function in women with obesity

JCI Insight(2023)10.1172/jci.insight.169541

N/A

0DataRank · unranked

8 citations

Brandon D. Kayser, Mihoko Yoshino, Jun Yoshino, Jeramie D. Watrous, Mohit Jain +4 more

Metabolically Healthy Obesity is not a Myth

JCEM Case Reports(2023)10.1210/jcemcr/luad015

N/A

0DataRank · unranked

5 citations

Gordon I. Smith, Jun Yoshino, Samuel Klein, Sarah S. Farabi

β Cell function after Roux-en-Y gastric bypass surgery or reduced energy intake alone in people with obesity

JCI Insight(2023)10.1172/jci.insight.170307

N/A

0DataRank · unranked

4 citations

Bruce W. Patterson, Faidon Magkos, Mihoko Yoshino, David Bradley, J. Christopher Eagon +2 more

Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans

Nature(2021)10.1038/s41586-021-03671-4

N/A

0DataRank · unranked

141 citations

Chandni Desai, Arjun S. Raman, Robert Y. Chen, Matthew C. Hibberd, Jiye Cheng +20 more

Short-term cold exposure induces persistent epigenomic memory in brown fat

Cell Metabolism(2024)10.1016/j.cmet.2024.05.011

N/A

0DataRank · unranked

37 citations

Matthew J. Emmett, Hee‐Woong Lim, Mohit Midha, Hannah J. Richter, Isaac J. Celwyn +6 more

Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH

Cell Reports(2021)10.1016/j.celrep.2020.108626

N/A

0DataRank · unranked

363 citations

Anastasiia Gainullina, Gowri Kalugotla, Li He, Mandy M. Chan, Joseph W. Beals +7 more

Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes

Cell Metabolism(2021)10.1016/j.cmet.2021.08.002

N/A

0DataRank · unranked

436 citations

Jan‐Bernd Funcke, Shujuan Li, Nolwenn Joffin, Christy Gliniak, Alexandra L. Ghaben +11 more

A Critical Role of Hepatic GABA in The Metabolic Dysfunction and Hyperphagia of Obesity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.02.022699

N/A

0DataRank · unranked

4 citations

Susma Ghimire, Stephanie Bruggink, Kendra E. Miller, Savanna N. Weninger, Jason M. Kronenfeld +5 more

Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction

Scientific Reports(2020)10.1038/s41598-020-60290-1

N/A

0DataRank · unranked

25 citations

Rugmani Padmanabhan Iyer, Christopher A. Novotny, Daniel METZGER, Heather Zhou, Gordon I. Smith +7 more

Effects of Obesity and Hyperglycemia on Postprandial Insulin-Mediated and Non–Insulin-Mediated Glucose Disposal

Diabetes Care(2024)10.2337/dc24-1280

N/A

0DataRank · unranked

5 citations

Bruce W. Patterson, Gordon I. Smith, Mihoko Yoshino, Samuel Klein, Bettina Mittendorfer

Impaired plasma glucose clearance is a key determinant of fasting hyperglycemia in people with obesity

Obesity(2024)10.1002/oby.23963

N/A

0DataRank · unranked

4 citations

Stephan van Vliet, Gordon I. Smith, Max C. Petersen, Bruce W. Patterson, Samuel Klein +1 more

Methods and validation of velacur determined fat fraction in patients with MASLD

WFUMB Ultrasound Open(2024)10.1016/j.wfumbo.2024.100061

N/A

0DataRank · unranked

1 citations

Julio Lobo, Caitlin Schneider, Samuel Klein, Gordon I. Smith, Rohit Loomba +7 more

MXRA8 promotes adipose tissue whitening to drive obesity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.31.578211

N/A

0DataRank · unranked

0 citations

Rocky Giwa, John R. Moley, Gordon I. Smith, Max C. Petersen, Rachael L. Field +13 more

Response to Comment on Samovski et al. Effect of Marked Weight Loss on Adipose Tissue Biology in People With Obesity and Type 2 Diabetes. Diabetes Care 2025;48:1342–1351

Diabetes Care(2025)10.2337/dci25-0101

N/A

0DataRank · unranked

1 citations

Gordon I. Smith, Hector H. Palacios, Terri Pietka, Anja Fuchs, Gary J. Patti +4 more

Isotope tracing-based metabolite identification for mass spectrometry metabolomics

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.07.647691

N/A

0DataRank · unranked

2 citations

Arjana Begzati, Nina Grankvist, Irena Roçi, Jeramie D. Watrous, Amit R. Majithia +5 more

Whole body and hematopoietic cell-specific deletion of G-protein coupled receptor 65 (GPR65) improves insulin sensitivity in diet-induced obese mice

Molecular Metabolism(2025)10.1016/j.molmet.2025.102169

N/A

0DataRank · unranked

0 citations

E. H. Bae, Simon S. Hoffman, Da Young Oh, Gordon I. Smith, Samuel Klein +2 more

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.11.664236

N/A

0DataRank · unranked

0 citations

Marjori Russo, Yun-Ling Pai, Wentong Jia, Rachael L. Field, Terri Pietka +7 more

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids

Cell Reports(2022)10.1016/j.celrep.2022.110733

N/A

0DataRank · unranked

50 citations

Manuel Gutiérrez‐Aguilar, Nicole K.H. Yiew, Andrew J. Lutkewitte, Jason Singer, Kyle S. McCommis +12 more

Influence of obesity and insulin resistance with hepatic steatosis on the human plasma lipidome

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100969

N/A

0DataRank · unranked

0 citations

Gordon I. Smith, Aaron M. Armando, Xiong Su, Oswald Quehenberger, Edward A. Dennis +2 more

Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

Nature Communications(2022)10.1038/s41467-022-28435-0

N/A

0DataRank · unranked

47 citations

Litao Xie, Ashutosh Kumar, Juan Hong, Pratik Rajesh Chheda, Kang Chen +25 more

ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP

Nature Metabolism(2022)10.1038/s42255-022-00667-w

N/A

0DataRank · unranked

57 citations

Charlotte Scholtes, Damien Lagarde, Mohammed F. Hussain, Anna Roesler, Christien B. Dykstra +27 more

Insufficient sleep and obesity: cause or consequence

Obesity(2022)10.1002/oby.23539

N/A

0DataRank · unranked

30 citations

Samuel Klein, Josiane L. Broussard

Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial

Nature Medicine(2022)10.1038/s41591-022-02011-x

N/A

0DataRank · unranked

57 citations

Schafer Boeder, Mark P. Christiansen, Douglas Denham, Timothy S. Bailey, Halis Kaan Aktürk +11 more

Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles

Hepatology(2022)10.1002/hep.32427

N/A

0DataRank · unranked

62 citations

Chiara Bruzzone, Mazen Noureddin, Rubén Gil‐Redondo, Itziar Mincholé, Maider Bizkarguenaga +36 more