Nickolas Papadopoulos

Also affiliated with Johns Hopkins Medicine, Sidney Kimmel Cancer Center, Sidney Kimmel Comprehensive Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

11.9Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Science(2006)10.1126/science.1133427

Top 1%

11.9DataRank

Top 1%3178 citations

Siân Jones, Laura D. Wood, D. Williams Parsons, Jimmy Lin, Thomas D. Barber +26 more

Papers

Driven by 59 papers — median percentile 99. Top paper: “Heteroplasmic mitochondrial DNA mutations in normal and tumour cells”.

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

Nature(2010)10.1038/nature08802

N/A

15.1DataRank · unranked

533 citations

Jian Wu, Devin C. Dressman, Christine Iacobuzio-Donahue, Sanford D. Markowitz, Victor E. Velculescu +5 more

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Science(2006)10.1126/science.1133427

Top 1%

11.9DataRank

Top 1%3178 citations

Siân Jones, Laura D. Wood, D. Williams Parsons, Jimmy Lin, Thomas D. Barber +26 more

Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies

International Journal of Cancer(2020)10.1002/ijc.33312

N/A

4.7DataRank · unranked

113 citations

Joshua D. Cohen, Serigne Lo, Yuxuan Wang, Lu Li, Michael Christie +23 more

Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-002473

N/A

2.5DataRank · unranked

67 citations

Karisa C. Schreck, Wei Fu, Chen Hu, Alexander Carvajal-González, Roisín M. Connolly +18 more

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Science(2017)10.1126/science.aan6733

N/A

1.3DataRank · unranked

6550 citations

Jennifer N. Durham, Kellie N. Smith, Hao Wang, Bjarne R. Bartlett, Laveet K. Aulakh +46 more

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

Science(2011)10.1126/science.1206923

N/A

1.1DataRank · unranked

1689 citations

Mitchell J. Frederick, Curtis R. Pickering, Chetan Bettegowda, Kyle Chang, Ryan J. Li +29 more

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

Science(2010)10.1126/science.1196333

N/A

1.1DataRank · unranked

1223 citations

Tian-Li Wang, Ie-Ming Shih, Tsui-Lien Mao, Kentaro Nakayama, Richard Roden +8 more

Altered Telomeres in Tumors with ATRX and DAXX Mutations

Science(2011)10.1126/science.1207313

N/A

1.0DataRank · unranked

1064 citations

Roeland F. de Wilde, Yuchen Jiao, Alison P. Klein, Barish H. Edil, Chanjuan Shi +20 more

Hypermutability and mismatch repair deficiency in RER+ tumor cells

Cell(1993)10.1016/0092-8674(93)90331-j

N/A

1.0DataRank · unranked

1058 citations

Guo-Min Li, Matthew J. Longley, Woei-horng Fang, Nickolas Papadopoulos, Jin Jen +7 more

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

Science(2020)10.1126/science.abb9601

N/A

0.977DataRank · unranked

673 citations

Adam H. Buchanan, Isaac Kinde, Andrew Warren, Ashley Honushefsky, Ariella Cohain +35 more

Targeting a neoantigen derived from a common TP53 mutation

Science(2021)10.1126/science.abc8697

N/A

0.880DataRank · unranked

351 citations

Katharine M. Wright, Jacqueline Douglass, Michael S. Hwang, Brian J. Mog, Alexander H. Pearlman +20 more

Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer: Overall survival and updated 5-year results from the randomized DYNAMIC trial.

Journal of Clinical Oncology(2024)10.1200/jco.2024.42.16_suppl.108

N/A

0.837DataRank · unranked

15 citations

Yuxuan Wang, Serigne Lo, Kamel Lahouel, Joshua D. Cohen, Rachel Wong +15 more

The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer

Cancer Discovery(2023)10.1158/2159-8290.cd-21-1252

N/A

0.772DataRank · unranked

171 citations

Christopher Douville, Yuxuan Wang, Maria Popoli, Janine Ptak, Natalie Silliman +18 more

Machine learning to detect the SINEs of cancer

Science Translational Medicine(2024)10.1126/scitranslmed.adi3883

N/A

0.767DataRank · unranked

22 citations

Kamel Lahouel, Albert Kuo, Haley Grant, Bracha Erlanger Avigdor, Samuel D. Curtis +33 more

Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations

Proceedings of the National Academy of Sciences(2017)10.1073/pnas.1701382114

N/A

0.700DataRank · unranked

16 citations

Yuxuan Wang, Simeon Springer, Joshua D. Cohen, Srinivasan Yegnasubramanian, William G. Nelson +4 more

Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer: 5-year outcomes of the randomized DYNAMIC trial

Nature Medicine(2025)10.1038/s41591-025-03579-w

N/A

0.691DataRank · unranked

99 citations

Yuxuan Wang, Serigne Lo, Kamel Lahouel, Joshua D. Cohen, Rachel Wong +24 more

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival

Nature Communications(2020)10.1038/s41467-020-17386-z

N/A

0.683DataRank · unranked

94 citations

Tabitha A. Harrison, Amanda I. Phipps, Robert S. Steinfelder, Quang M. Trinh, Conghui Qu +71 more

Assessing aneuploidy with repetitive element sequencing

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1910041117

N/A

0.663DataRank · unranked

82 citations

Joshua D. Cohen, Janine Ptak, Maria Popoli, Joy Schaefer, Natalie Silliman +17 more

Targeting loss of heterozygosity for cancer-specific immunotherapy

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2022410118

N/A

0.652DataRank · unranked

76 citations

Brian J. Mog, Jacqueline Douglass, Alexander H. Pearlman, Emily Han-Chung Hsiue, Suman Paul +10 more

Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with Fusobacterium nucleatum and Its Subspecies animalis

Cancer Epidemiology Biomarkers & Prevention(2021)10.1158/1055-9965.epi-21-0463

N/A

0.617DataRank · unranked

60 citations

Syed Hassan Ejaz Zaidi, Tabitha A. Harrison, Amanda I. Phipps, Jiayin Zheng, Stephen Dongsoo Lee +35 more

TCR β chain–directed bispecific antibodies for the treatment of T cell cancers

Science Translational Medicine(2021)10.1126/scitranslmed.abd3595

N/A

0.612DataRank · unranked

58 citations

Alexander H. Pearlman, Jacqueline Douglass, Brian J. Mog, Emily Han-Chung Hsiue, Michael S. Hwang +15 more

Ultrasensitive detection of tumor‐specific mutations in saliva of patients with oral cavity squamous cell carcinoma

Cancer(2021)10.1002/cncr.33393

N/A

0.584DataRank · unranked

48 citations

Arun K Hariharan, Rifat Hasina, Jayalakshmi Nair, Shanmukh Katragadda, Sivaraj Irusappan +20 more

TRBC1-targeting antibody–drug conjugates for the treatment of T cell cancers

Nature(2024)10.1038/s41586-024-07233-2

N/A

0.574DataRank · unranked

45 citations

Jiaxin Ge, Brian J. Mog, Bum Seok Lee, Alexander H. Pearlman, Michael S. Hwang +22 more

Circulating tumor DNA analysis informing adjuvant chemotherapy in locally advanced rectal cancer: The randomized AGITG DYNAMIC-Rectal study.

Journal of Clinical Oncology(2024)10.1200/jco.2024.42.3_suppl.12

N/A

0.564DataRank · unranked

42 citations

Joshua D. Cohen, Yuxuan Wang, Pablo Gonzalez Ginestet, Rachel Wong, Jeremy Shapiro +15 more

Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220704120

N/A

0.561DataRank · unranked

41 citations

Christopher Douville, Joshua D. Cohen, Austin K. Mattox, Sam Curtis, Natalie Silliman +16 more

Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens

Nature Communications(2021)10.1038/s41467-021-25605-4

N/A

0.553DataRank · unranked

39 citations

Michelle S. Miller, Puchong Thirawatananond, Jacqueline Douglass, Katharine M. Wright, Emily Han-Chung Hsiue +17 more

Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen

Nature Communications(2023)10.1038/s41467-023-40821-w

N/A

0.489DataRank · unranked

25 citations

Sarah R. DiNapoli, Michelle S. Miller, P. Aitana Azurmendi, Xiaowei Zhao, Zhiheng Yu +17 more

Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities

Science Translational Medicine(2024)10.1126/scitranslmed.adg7123

N/A

0.489DataRank · unranked

25 citations

Nikita Marcou, Sarah R. DiNapoli, Alexander H. Pearlman, Tushar D. Nichakawade, Michael S. Hwang +19 more

ctDNA-guided adjuvant chemotherapy escalation in stage III colon cancer: Primary analysis of the ctDNA-positive cohort from the randomized AGITG dynamic-III trial (intergroup study of AGITG and CCTG).

Journal of Clinical Oncology(2025)10.1200/jco.2025.43.16_suppl.3503

N/A

0.470DataRank · unranked

22 citations

Yuxuan Wang, Jonathan M. Loree, Joshua D. Cohen, David Espinosa Espinosa, Rachel Wong +15 more

Seq-ing the SINEs of central nervous system tumors in cerebrospinal fluid

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101148

N/A

0.442DataRank · unranked

18 citations

Samuel M. Curtis, Mahmoud Summers, Tej D. Azad, Jordina Rincón-Torroella, Yuxuan Wang +35 more

Detection of Cancers Three Years prior to Diagnosis Using Plasma Cell-Free DNA

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0375

N/A

0.416DataRank · unranked

15 citations

Corinne E. Joshu, Samuel D. Curtis, Christopher Douville, Vernon A. Burk, Meng Ru +13 more

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

eLife(2024)10.7554/elife.95952

N/A

0.406DataRank · unranked

10 citations

Surojit Sur, Laura Dobbyn, Evangeline Watson, Joshua D. Cohen, Blair Ptak +12 more

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.28.573594

N/A

0.331DataRank · unranked

4 citations

Surojit Sur, Laura Dobbyn, Evangeline Watson, Joshua D. Cohen, Blair Ptak +12 more

Fragmentation signatures in cancer patients resemble those of patients with vascular or autoimmune diseases

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2426890122

N/A

0.330DataRank · unranked

8 citations

Tingshan Liu, Yuhang Bai, Yuxuan Wang, Sambit Panda, Adam Li +38 more

Tumor DNA as a Cancer Biomarker through the Lens of Colorectal Neoplasia

Cancer Epidemiology Biomarkers & Prevention(2020)10.1158/1055-9965.epi-20-0549

N/A

0.330DataRank · unranked

8 citations

Brenda Diergaarde, Nickolas Papadopoulos, Kenneth W. Kinzler, Robert E. Schoen, Joshua D. Cohen

The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

Nature Communications(2023)10.1038/s41467-022-35668-6

N/A

0.312DataRank · unranked

7 citations

Austin K. Mattox, P. Aitana Azurmendi, Ilias Christodoulou, Katharine M. Wright, Maria Popoli +11 more

Detection of Human Brain Cancers using Genomic and Immune Cell Characterization of Cerebrospinal Fluid through CSF-BAM

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1788

N/A

0.257DataRank · unranked

4 citations

Yuxuan Wang, Anita Kalluri, Megan Parker, Joshua D. Cohen, Jonathan C. Dudley +37 more

Minimizing and quantifying uncertainty in AI-informed decisions: Applications in medicine

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2424203122

N/A

0.241DataRank · unranked

4 citations

Sambit Panda, Adam Li, Haoyin Xu, Yuhang Bai, Itsuki Ogihara +29 more

NXPE1 alters the sialoglycome by acetylating sialic acids in the human colon

Nature Communications(2025)10.1038/s41467-025-59671-9

N/A

0.241DataRank · unranked

4 citations

Ashley L. Cook, Surojit Sur, Laura Dobbyn, Maria Popoli, Sana Khalili +9 more

identifying cancer patients from GC-patterned fragment ends of cell-free DNA

medRxiv(2022)10.1101/2022.08.02.22278319

N/A

0.222DataRank · unranked

3 citations

Mahmoud Summers, Joshua D. Cohen, Yuxuan Wang, Nadine Nehme, Maria Popoli +17 more

Molecular Evidence of Multiorgan Damage in Patients with Immune-Related Adverse Events

New England Journal of Medicine(2025)10.1056/nejmc2513984

N/A

0.208DataRank · unranked

3 citations

Howard L. Li, Chetan Bettegowda, Kenneth W. Kinzler, Nickolas Papadopoulos, Mark Yarchoan +2 more

Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients

Frontiers in Medicine(2022)10.3389/fmed.2022.849222

N/A

0.208DataRank · unranked

3 citations

Tomi Jun, Jonathan Tyler, Emilio Schadt, Yu-Han Kao, Zichen Wang +10 more

TRBC2-targeting antibody–drug conjugates for the treatment of T cell cancers

Nature Cancer(2025)10.1038/s43018-025-01069-z

N/A

0.165DataRank · unranked

2 citations

Joshua Urban, Sarah R. DiNapoli, Bum Seok Lee, Taha Ahmedna, Tushar D. Nichakawade +26 more

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

eLife(2024)10.7554/elife.94488

N/A

0.111DataRank · unranked

1 citations

Marco Dal Molin, Brian J. Mog, Gyuri Han, Evangeline Watson, Nicolas Wyhs +12 more

Detection of rare mutations, copy number variation, and DNA methylation in the same template DNA molecules

medRxiv(2022)10.1101/2022.12.06.22283116

N/A

0.104DataRank · unranked

1 citations

Christopher Douville, Joshua D. Cohen, Austin K. Mattox, Sam Curtis, Natalie Silliman +12 more

Engineering immunotoxin-equipped effector cells and evaluation in primary human immune cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.09.691975

N/A

0.104DataRank · unranked

1 citations

Brian J. Mog, Michael S. Hwang, Jordina Rincón-Torroella, Sarah R. DiNapoli, Suman Paul +11 more

Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett’s Esophagus

Gastroenterology(2021)10.1053/j.gastro.2021.01.209

N/A

0DataRank · unranked

32 citations

Helen Moinova, Prashanthi N. Thota, Nicholas J. Shaheen, Prasad G. Iyer, Marcia Irene Canto +11 more

Cancer therapy with antibodies

Nature reviews. Cancer(2024)10.1038/s41568-024-00690-x

N/A

0DataRank · unranked

221 citations

Maximilian F. Konig, Drew M. Pardoll, Chetan Bettegowda, Nickolas Papadopoulos, Katharine M. Wright +5 more

Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists

Journal of Clinical Investigation(2020)10.1172/jci139642

N/A

0DataRank · unranked

121 citations

Michael Powell, Verena Staedtke, Ren-Yuan Bai, David L. Thomas, Nicole Fischer +13 more

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.23.550207

N/A

0DataRank · unranked

1 citations

Marco Dal Molin, Brian J. Mog, Gyuri Han, Evangeline Watson, Nicolas Wyhs +12 more

Seq-ing the SINEs of Central Nervous System Tumors in Cerebrospinal Fluid DNA

medRxiv(2022)10.1101/2022.06.28.22276835

N/A

0DataRank · unranked

0 citations

Samuel M. Curtis, Mahmoud Summers, Tej D. Azad, Jordina Rincón-Torroella, Bracha Erlanger Avigdor +33 more

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

eLife(2024)10.7554/elife.94488.1

N/A

0DataRank · unranked

0 citations

Marco Dal Molin, Brian J. Mog, Gyuri Han, Evangeline Watson, Nicolas Wyhs +12 more

Reviewer #2 (Public review): ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

(2024)10.7554/elife.94488.2.sa1

N/A

0DataRank · unranked

0 citations

Marco Dal Molin, Brian Mog, Gyuri Han, Evangeline Watson, Nicolas Wyhs +12 more

A Blood-Based Assay for Detection of Patients with Advanced Adenomas

Cancer Research Communications(2025)10.1158/2767-9764.crc-24-0398

N/A

0DataRank · unranked

2 citations

Christopher Douville, Brenda Diergaarde, Joshua D. Cohen, Haley Grant, Albert Kuo +16 more

Integrated Spatial Analysis Reveals the Molecular Landscape of Ovarian Precancerous Lesions

Cancer Research(2025)10.1158/0008-5472.can-25-3189

N/A

0DataRank · unranked

2 citations

Yen‐Wei Chien, S. S. Chen, Annelise Sokolow, Yeh Wang, Brant G. Wang +10 more

An isogenic cell line panel for sequence-based screening of targeted anticancer drugs

iScience(2022)10.1016/j.isci.2022.104437

N/A

0DataRank · unranked

14 citations

Nicolas Wyhs, Surojit Sur, Blair Ptak, Maria Popoli, Laura Dobbyn +7 more

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

eLife(2025)10.7554/elife.94488.3

N/A

0DataRank · unranked

0 citations

Marco Dal Molin, Brian J. Mog, Gyuri Han, Evangeline Watson, Nicolas Wyhs +12 more

Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma

eLife(2022)10.7554/elife.74238

N/A

0DataRank · unranked

24 citations

Christopher Douville, Natalie Silliman, Janine Ptak, Lisa Dobbyn, Joy Schaefer +11 more

An Isogenic Cell Line Panel for Sequence-based Screening of Targeted Anti-cancer Drugs

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.06.455336

N/A

0DataRank · unranked

0 citations

Nicolas Wyhs, Surojit Sur, Blair Ptak, Maria Popoli, Laura Dobbyn +7 more

Nickolas Papadopoulos

Indexed papers

Top data-sharing exemplar

Papers