Jeffrey R. Moore

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 16 papers. Top paper: “Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation”.

Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation

The Journal of General Physiology(2021)10.1085/jgp.202012640

N/A

0.520DataRank · unranked

31 citations

Jin‐Kyu Park, Michael J. Rynkiewicz, Alice Ward Racca, Nikolaos Papoutsidakis, Jonas Schwan +6 more

Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TPM1 variant S215L

PNAS Nexus(2023)10.1093/pnasnexus/pgad011

N/A

0.496DataRank · unranked

14 citations

Michael J. Rynkiewicz, Jenette G. Creso, Lorenzo R. Sewanan, Lindsey Howland, Jeffrey R. Moore +3 more

Proteasome activity modulates amyloid toxicity

FEMS Yeast Research(2022)10.1093/femsyr/foac004

N/A

0.165DataRank · unranked

2 citations

Liz Curran, Francisco Moreno, Alicia Goossens, Nicki L. Aubuchon‐Endsley, Michael A. McMurray +7 more

Dual role of Tropomyosin-R160 in thin filament regulation: Insights into phosphorylation-dependent cardiac relaxation and cardiomyopathy mechanisms

Archives of Biochemistry and Biophysics(2025)10.1016/j.abb.2025.110380

N/A

0.104DataRank · unranked

1 citations

Michael J. Rynkiewicz, Wen Jian, An-Yue Tu, Michael Regnier, William Lehman +2 more

Bridging the muscle genome to phenome across multiple biological scales

Journal of Experimental Biology(2022)10.1242/jeb.243630

N/A

0DataRank · unranked

4 citations

Barbora Rimkus, Prabath S. Meemaduma, Samuel deLap, Nicholas LaFave, Alice Ward Racca +6 more

Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.23.509077

N/A

0DataRank · unranked

0 citations

Michael J. Rynkiewicz, D. Rassici, Skylar M.L. Bodt, Meaghan E. Barry, Esther Bullitt +4 more

Multi-scale modeling will unravel connections between sarcomeric mutations and cardiomyopathies

Journal of Molecular and Cellular Cardiology Plus(2022)10.1016/j.jmccpl.2022.100025

N/A

0DataRank · unranked

0 citations

Jeffrey R. Moore, Michael J. Rynkiewicz, William Lehman, Stuart G. Campbell

Distinct mechanisms drive divergent phenotypes in hypertrophic and dilated cardiomyopathy–associated TPM1 variants

Journal of Clinical Investigation(2024)10.1172/jci179135

N/A

0DataRank · unranked

10 citations

Michael J. Rynkiewicz, Lynne Kim, Meaghan E. Barry, Ahmed Zied, Lorenzo R. Sewanan +5 more

Glutamate 139 of tropomyosin is critical for cardiac thin filament blocked-state stabilization

Journal of Molecular and Cellular Cardiology(2024)10.1016/j.yjmcc.2024.01.004

N/A

0DataRank · unranked

8 citations

Michael J. Rynkiewicz, Elumalai Pavadai, Alex Viana, William Lehman, Jeffrey R. Moore +1 more

In silico and in vitro models reveal the molecular mechanisms of hypocontractility caused by TPM1 M8R

Frontiers in Physiology(2024)10.3389/fphys.2024.1452509

N/A

0DataRank · unranked

3 citations

Ilhan Gokhan, Michael J. Rynkiewicz, William Lehman, Jeffrey R. Moore, Stuart G. Campbell +1 more

Screening single nucleotide changes to tropomyosin to identify novel cardiomyopathy mutants

Journal of Molecular and Cellular Cardiology(2025)10.1016/j.yjmcc.2025.04.009

N/A

0DataRank · unranked

0 citations

Stuart G. Campbell, Jeffrey R. Moore, William Lehman, Michael J. Rynkiewicz, Wen Jian

Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments

Biophysical Journal(2020)10.1016/j.bpj.2020.07.006

N/A

0DataRank · unranked

56 citations

Elumalai Pavadai, Michael J. Rynkiewicz, Jonathan Walklate, Esther Bullitt, Jeffrey R. Moore +4 more

Evaluating pathogenicity of TPM1 variants of unknown significance using in-silico and in-vitro models

The Journal of Precision Medicine Health and Disease(2025)10.1016/j.premed.2025.100008

N/A

0DataRank · unranked

0 citations

Jenette G. Bellitto, Michael J. Rynkiewicz, Fanny Cheung, Darren Liu, Ilayda Firlar +7 more

Phosphorylation-dependent power output of transgenic flies: an integrated study

UNC Libraries(2020)10.17615/s60t-ts50

N/A

0DataRank · unranked

0 citations

Rutawain Tohtong, Amanda Simcox, Fritz Lehmann, Michael H. Dickinson, David W. Maughan +5 more

Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin

The Journal of General Physiology(2022)10.1085/jgp.202213267

N/A

0DataRank · unranked

30 citations

Michael J. Rynkiewicz, David V. Rasicci, Skylar M.L. Bodt, Meaghan E. Barry, Esther Bullitt +4 more

Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation

The Journal of General Physiology(2022)10.1085/jgp.202213274

N/A

0DataRank · unranked

17 citations

Michael J. Rynkiewicz, Elumalai Pavadai, Skylar M.L. Bodt, David V. Rasicci, Jeffrey R. Moore +4 more