R. Jude Samulski

University of North Carolina at Chapel Hill

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 60 papers. Top paper: “Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles”.

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

UNC Libraries(2020)10.17615/ttbf-4y95

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0.269DataRank · unranked

5 citations

Stefan W. Leichtle, Lakshmanan Govindaswamy, Mavis Agbandje‐McKenna, D. Eugene Redmond, Thomas J. McCown +9 more

Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy

UNC Libraries(2020)10.17615/7faj-dh75

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0DataRank · unranked

16 citations

Paul T. Rubery, Takashi Nakamura, Xinping Zhang, Jonathan J. Carmouche, Brendan F. Boyce +10 more

Intrastromal Gene Therapy Prevents and Reverses Advanced Corneal Clouding in a Canine Model of Mucopolysaccharidosis I

Molecular Therapy(2020)10.1016/j.ymthe.2020.04.004

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0DataRank · unranked

34 citations

Laura Conatser, Telmo Llanga, Kendall Carlin, Patricia O’Donnell, Jessica Bagel +6 more

Development of AAV Variants with Human Hepatocyte Tropism and Neutralizing Antibody Escape Capacity

Molecular Therapy — Methods & Clinical Development(2020)10.1016/j.omtm.2020.06.003

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29 citations

Wenwei Shao, Allene Xing, Charles Askew, Xiaojing Chen, Caibin Cui +8 more

Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues

PLoS ONE(2020)10.1371/journal.pone.0242599

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5 citations

Charles Askew, Mark A. Brimble, R. Jude Samulski, Andrew M. Davidoff, Chengwen Li +2 more

Adeno-associated virus capsid antigen presentation is dependent on endosomal escape

UNC Libraries(2020)10.17615/zqtq-z877

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2 citations

Chengwen Li, Matt Hirsch, Yi He, R. Jude Samulski, Sarah C. Nicolson +3 more

Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates

UNC Libraries(2020)10.17615/7tm6-fk29

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8 citations

Sahana Nagabhushan Kalburgi, R. Jude Samulski, T J McCown, S J Gray

Overexpression of SOD in retina: Need for increase in H2O2-detoxifying enzyme in same cellular compartment

UNC Libraries(2020)10.17615/smgp-6298

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5 citations

Brian C. Oveson, Eunyoung Choi, Sun Young Lee, Shinichi Usui, Young–Joon Jo +5 more

Generation of Novel AAV Variants by Directed Evolution for Improved CFTR Delivery to Human Ciliated Airway Epithelium

UNC Libraries(2020)10.17615/vfay-5z44

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3 citations

Zhijian Wu, Ping‐Jie Xiao, R. Jude Samulski, Jarrod S. Johnson, Joshua C. Grieger +5 more

Efficient Transduction of Vascular Endothelial Cells with Recombinant Adeno-Associated Virus Serotype 1 and 5 Vectors

UNC Libraries(2020)10.17615/yqj9-s373

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2 citations

R. Jude Samulski, Kenneth I. Berns, Kirsten Madsen, C. Craig Tisher, Terence R. Flotte +9 more

Engraftment of a Galactose Receptor Footprint onto Adeno-associated Viral Capsids Improves Transduction Efficiency

UNC Libraries(2020)10.17615/rt2n-kg40

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2 citations

Shen Shen, Eric D. Horowitz, Mavis Agbandje‐McKenna, Andrew N. Troupes, Nagesh Pulicherla +3 more

Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell Lines In Vitro and in Murine Hepatocytes In Vivo

UNC Libraries(2020)10.17615/7w6y-pk12

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2 citations

Thomas Lentz, Wenqin Ma, Xiao Xiao, Yuan Wang, George Aslanidi +10 more

Kinetics of Adeno-Associated Virus Serotype 2 (AAV2) and AAV8 Capsid Antigen Presentation In Vivo Are Identical

UNC Libraries(2020)10.17615/5m38-rx26

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1 citations

Matt Hirsch, Mark C. Johnson, Marc S. Weinberg, Yi He, R. Jude Samulski +2 more

Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer

UNC Libraries(2020)10.17615/026a-n533

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1 citations

Chengwen Li, Aravind Asokan, Mavis Agbandje‐McKenna, Wuping Li, Scott McPhee +5 more

Oversized AAV Transductifon Is Mediated via a DNA-PKcs-independent, Rad51C-dependent Repair Pathway

UNC Libraries(2020)10.17615/xz6p-va60

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1 citations

Chaoying Yin, Chengwen Li, R. Jude Samulski, Isabelle Richard, Matthew L. Hirsch +3 more

Wild type AAV, recombinant AAV, and Adenovirus super infection impact on AAV vector mobilization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.13.094201

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1 citations

R. Jude Samulski, Matthew L. Hirsch, Liujiang Song

Proteasome Inhibitors Enhance Gene Delivery by AAV Virus Vectors Expressing Large Genomes in Hemophilia Mouse and Dog Models: A Strategy for Broad Clinical Application

UNC Libraries(2020)10.17615/a4m7-hc13

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0 citations

R. Jude Samulski, Clinton D. Lothrop, Boris Kantor, Matthew L. Hirsch, Joseph R Elia +5 more

Disruption of Microtubules Post-Virus Entry Enhances Adeno-Associated Virus Vector Transduction

UNC Libraries(2020)10.17615/9xrd-ke58

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0DataRank · unranked

0 citations

Chengwen Li, Ping‐Jie Xiao, Angela M. Mitchell, Lu Huang, R. Jude Samulski

Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure

UNC Libraries(2020)10.17615/1chy-8v44

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0DataRank · unranked

0 citations

Daniel C. Sigg, Fadi G. Akar, Evangelia G. Kranias, Scott McPhee, Kenneth Fish +15 more

Insight into the Mechanism of Inhibition of Adeno-Associated Virus by the Mre11/Rad50/Nbs1 Complex

UNC Libraries(2020)10.17615/jqab-ty38

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0 citations

Thomas B. Lentz, R. Jude Samulski

Optimization of scAAVIL-1ra In Vitro and In Vivo to Deliver High Levels of Therapeutic Protein for Treatment of Osteoarthritis

UNC Libraries(2020)10.17615/g59r-mw33

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0DataRank · unranked

0 citations

R. Jude Samulski, Joshua C. Grieger, Jennifer N. Phillips, Laurie R. Goodrich, C Wayne McIlwraith +2 more

AAVs Anatomy: Roadmap for Optimizing Vectors for Translational Success

UNC Libraries(2020)10.17615/f4bt-w697

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0DataRank · unranked

0 citations

Jayme K. Warischalk, R. Jude Samulski, Sarah C. Nicolson, Angela M. Mitchell

Creating a Novel Origin of Replication through Modulating DNA-Protein Interfaces

UNC Libraries(2020)10.17615/6azy-c660

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0 citations

F. Curtis Hewitt, R. Jude Samulski

AAV Recombineering with Single Strand Oligonucleotides

UNC Libraries(2020)10.17615/3wy3-0g19

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0DataRank · unranked

0 citations

Matthew L. Hirsch, Francesca Storici, Vivian W. Choi, Chengwen Li, R. Jude Samulski

Employing a Gain-of-Function Factor IX Variant R338L to Advance the Efficacy and Safety of Hemophilia B Human Gene Therapy: Preclinical Evaluation Supporting an Ongoing Adeno-Associated Virus Clinical Trial

UNC Libraries(2020)10.17615/fzyc-s786

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0 citations

Tong Gui, Scott McPhee, Carmen J. Booth, Junjiang Sun, Tal Kafri +11 more

Adeno-Associated Viral Vectors Show Serotype Specific Transduction of Equine Joint Tissue Explants and Cultured Monolayers

UNC Libraries(2020)10.17615/mpqq-sp13

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0 citations

R. Jude Samulski, Laurie R. Goodrich, C. Wayne McIlwraith, Daniel D. Hemphill

Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62LloFoxP3+CD4+ T cells with limited suppressor activity

UNC Libraries(2020)10.17615/j601-tq87

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0 citations

Bo Wang, Kevin Goudy, Roland Tisch, Mark C. Johnson, Alaina L. Garland +2 more

AAV Exploits Subcellular Stress Associated with Inflammation, Endoplasmic Reticulum Expansion, and Misfolded Proteins in Models of Cystic Fibrosis

UNC Libraries(2020)10.17615/1jpg-kr69

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0 citations

Jarrod S. Johnson, Tal Kafri, Liqun Zhang, Boris Kantor, Martina Gentzsch +3 more

Biology of adeno-associated viral vectors in the central nervous system

UNC Libraries(2020)10.17615/gvx8-7082

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0DataRank · unranked

0 citations

Aravind Asokan, Giridhar Murlidharan, R. Jude Samulski

K137R Mutation on Adeno-Associated Viral Capsids Had Minimal Effect on Enhancing Gene Delivery In Vivo

UNC Libraries(2020)10.17615/x7ww-2n68

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0DataRank · unranked

0 citations

Xiao Xiao, R. Jude Samulski, Jianbin Li, Chunping Qiao, Joshua C. Grieger +4 more

Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction following High-Throughput Screens

UNC Libraries(2020)10.17615/fd8m-ja44

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0DataRank · unranked

0 citations

Vincent Setola, Chengwen Li, Matthew L. Hirsch, Sarah C. Nicolson, R. Jude Samulski

β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice

UNC Libraries(2020)10.17615/kr74-7d60

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0 citations

Mark C. Johnson, Roland Tisch, Fatima Manzoor, Bo Wang, Chengwen Li +1 more

AAV9.I-1c Delivered via Direct Coronary Infusion in a Porcine Model of Heart Failure Improves Contractility and Mitigates Adverse Remodeling

UNC Libraries(2020)10.17615/9349-br56

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0DataRank · unranked

0 citations

Kenneth Fish, Lisa Tilemann, Hung Q. Ly, Evangelia G. Kranias, Kiyotake Ishikawa +8 more

An Emerging Adeno-Associated Viral Vector Pipeline for Cardiac Gene Therapy

UNC Libraries(2020)10.17615/xkmk-bs02

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0 citations

R. Jude Samulski, Aravind Asokan

Viral Single-Strand DNA Induces p53-Dependent Apoptosis in Human Embryonic Stem Cells

UNC Libraries(2020)10.17615/5zwr-a987

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0DataRank · unranked

0 citations

Swati Yadav, Matthew L. Hirsch, Larysa Pevny, Jacquelyn J. Bower, Matthew H. Porteus +3 more

Mechanistic Insights into the Enhancement of Adeno-Associated Virus Transduction by Proteasome Inhibitors

UNC Libraries(2020)10.17615/9yec-8s06

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0 citations

Angela M. Mitchell, R. Jude Samulski

Heparan Sulfate Binding Promotes Accumulation of Intravitreally Delivered Adeno-associated Viral Vectors at the Retina for Enhanced Transduction but Weakly Influences Tropism

UNC Libraries(2020)10.17615/5111-bd71

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0 citations

R. Jude Samulski, William Bennett, Kenton Woodard, Katharine J. Liang

Parkinson's Disease Gene Therapy: Success by Design Meets Failure by Efficacy

UNC Libraries(2020)10.17615/1c04-4n54

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0 citations

R. Jude Samulski, Raymond T. Bartus, Marc S. Weinberg

AAV-6 mediated efficient transduction of mouse lower airways

UNC Libraries(2020)10.17615/bfdq-0e29

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0 citations

Liqun Zhang, Zhijian Wu, R. Jude Samulski, Wuping Li, Raymond J. Pickles

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

UNC Libraries(2020)10.17615/k4e8-xw30

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0 citations

L. Govindasamy, Juan Li, Chengwen Li, Dawn E. Bowles, Xiao Xiao +10 more

The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings

UNC Libraries(2020)10.17615/sftc-mx50

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0 citations

Chao Xie, R. Jude Samulski, Xinping Zhang, Laura Yanoso, Edward M. Schwarz +6 more

The AAV Vector Toolkit: Poised at the Clinical Crossroads

UNC Libraries(2020)10.17615/jrjj-rf40

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0 citations

R. Jude Samulski, Aravind Asokan, David V. Schaffer

Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model

UNC Libraries(2020)10.17615/w2nz-2418

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0 citations

Christopher H. Evans, Julie A. Wilder, JeanClare Seagrave, Janet M. Benson, Julie A. Hutt +4 more

Customized blood-brain barrier shuttle peptide to increase AAV9 vector crossing the BBB and augment transduction in the brain

Biomaterials(2021)10.1016/j.biomaterials.2021.121340

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20 citations

Zheng Chai, Amanda L. Dobbins, Michelle S. Itano, Charles Askew, Zhe Miao +4 more

Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain

UNC Libraries(2021)10.17615/wfys-3673

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8 citations

R. Jude Samulski, Jerillyn Sifford, Joseph Muenzer, Douglas M. McCarty, Haiyan Fu +2 more

VHL and PTEN loss coordinate to promote mouse liver vascular lesions

UNC Libraries(2021)10.17615/zg2v-vc86

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2 citations

W. Kimryn Rathmell, Christie A. Sanford, Junjiang Sun, Vivian W. Choi, Shufen Chen +2 more

Serotype-specific replicating AAV helper constructs increase recombinant AAV type 2 vector production

UNC Libraries(2021)10.17615/dgst-kz56

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1 citations

Chengwen Li, R. Jude Samulski

X-Linked Inhibitor of Apoptosis Protein-Mediated Attenuation of Apoptosis, Using a Novel Cardiac-Enhanced Adeno-Associated Viral Vector

UNC Libraries(2021)10.17615/5g4f-2f08

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0DataRank · unranked

0 citations

Gayathri R. Devi, Ava Krol, Valentino Piacentino, Carmelo A. Milano, Lan Mao +8 more

Promyelocytic Leukemia Protein Is a Cell-Intrinsic Factor Inhibiting Parvovirus DNA Replication

UNC Libraries(2021)10.17615/r0wn-y710

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0 citations

R. Jude Samulski, Matthew L. Hirsch, Angela M. Mitchell, Chengwen Li

Insertional Mutagenesis of AAV2 Capsid and the Production of Recombinant Virus

UNC Libraries(2021)10.17615/2f32-7c37

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0 citations

Weidong Xiao, Joseph E. Rabinowitz, R. Jude Samulski

AAV-6 mediated efficient transduction of mouse lower airways

UNC Libraries(2021)10.17615/b2qn-gk61

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0DataRank · unranked

0 citations

Zhijian Wu, Raymond J. Pickles, Wuping Li, R. Jude Samulski, Liqun Zhang

Building a Better Vector: The Manipulation of AAV Virions

UNC Libraries(2021)10.17615/w1ay-gn52

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0 citations

Joseph E. Rabinowitz, R. Jude Samulski

Chimeric Mice Engrafted With Canine Hepatocytes Exhibits Similar AAV Transduction Efficiency to Hemophilia B Dog

Frontiers in Pharmacology(2022)10.3389/fphar.2022.815317

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4 citations

Junjiang Sun, Xiaojing Chen, Amanda L. Dobbins, Elizabeth P. Merricks, R. Jude Samulski +3 more

AAV Vector Transduction Restriction and Attenuated Toxicity in hESCs via a Rationally Designed Inverted Terminal Repeat

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.30.498264

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1 citations

Nolan J. Brown, Jacquelyn J. Bower, R. Jude Samulski, Matthew L. Hirsch, Liujiang Song

Direct comparison of epifluorescence and immunostaining for assessing viral mediated gene expression in the primate brain

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.04.510807

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0 citations

Hala G. El-Nahal, Michele A. Basso, Elizabeth J. Jun, Alex R. Bautista, R. Jude Samulski +3 more

Direct Comparison of Epifluorescence and Immunostaining for Assessing Viral Mediated Gene Expression in the Primate Brain

Human Gene Therapy(2023)10.1089/hum.2022.194

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8 citations

Hala G. El-Nahal, Michele A. Basso, Elizabeth J. Jun, Alex R. Bautista, R. Jude Samulski +3 more

IL-1ra gene therapy in equine osteoarthritis improves physiological, anatomical, and biological outcomes of joint degeneration

Journal of the American Veterinary Medical Association(2024)10.2460/javma.24.02.0078

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11 citations

C. Wayne McIlwraith, Josh Grieger, Virginia B. Kraus, Thomas Stäbler, Natasha M. Werpy +4 more

Rationally engineered novel AAV capsids for intra-articular gene delivery

Molecular Therapy — Methods & Clinical Development(2024)10.1016/j.omtm.2024.101211

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8 citations

Susi Feng, Lizette Herrschaft, R. Jude Samulski, Chengwen Li, Wenjun Li

Adeno-Associated Virus Vector Mobilization, Risk Versus Reality

Human Gene Therapy(2020)10.1089/hum.2020.118

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17 citations

R. Jude Samulski, Matthew L. Hirsch, Liujiang Song

IL-1ra gene therapy in equine osteoarthritis improves physiological, anatomical, and biological outcomes of joint degeneration.

UNC Libraries(2024)10.17615/32w7-5851

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0DataRank · unranked

0 citations

Josh Grieger, Thomas Stäbler, Virginia B. Kraus, C Wayne McIlwraith, Natasha M. Werpy +4 more