Thomas R. Cech

Also affiliated with University of Colorado Boulder

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells”.

Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells

Molecular Cell(2020)10.1016/j.molcel.2020.11.044

N/A

0.631DataRank · unranked

66 citations

Anne R. Gooding, Robin D. Dowell, Thomas R. Cech, Daniel T. Youmans

The structure of human CST reveals a decameric assembly bound to telomeric DNA

Science(2020)10.1126/science.aaz9649

N/A

0DataRank · unranked

122 citations

Alexandra T. Barbour, Arthur J. Zaug, Karen J. Goodrich, Allison E. McKay, Deborah S. Wuttke +2 more

Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers

Molecular Oncology(2020)10.1002/1878-0261.12786

N/A

0DataRank · unranked

41 citations

Andrew J. Bonham, Thomas R. Cech, Teisha J. Rowland

Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-19-1244

N/A

0DataRank · unranked

34 citations

Grace N. Hibshman, Kevin Hu, Sarah E. Ferrara, James C. Costello, William Kim +4 more

Polycomb-mediated Genome Architecture Enables Long-range Spreading of H3K27 methylation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.27.223438

N/A

0DataRank · unranked

19 citations

Kathryn E. Yost, Sedona E. Murphy, Andreas Magg, Yicheng Long, M. Ryan Corces +6 more

Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA transcripts is driven by intron retention: implications for RNA-directed therapies

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.21.212514

N/A

0DataRank · unranked

1 citations

Ulrich Braunschweig, Heera K. Langner, Katarzyna Jastrzębska, Michael J. Smallegan, Benjamin J. Blencowe +4 more

Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention

Nature Communications(2021)10.1038/s41467-021-23221-w

N/A

0DataRank · unranked

54 citations

Ulrich Braunschweig, Heera K. Langner, Michael J. Smallegan, Josep Biayna, Evan P. Hass +6 more

CST does not evict elongating telomerase but prevents initiation by ssDNA binding

Nucleic Acids Research(2021)10.1093/nar/gkab942

N/A

0DataRank · unranked

38 citations

Ci Ji Lim, Conner L. Olson, Maria Carilli, Karen J. Goodrich, Deborah S. Wuttke +2 more

Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools

Methods(2021)10.1016/j.ymeth.2021.01.002

N/A

0DataRank · unranked

6 citations

Thomas R. Cech, Yicheng Long

Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2201883119

N/A

0DataRank · unranked

113 citations

Kathryn E. Yost, Sedona E. Murphy, Andreas Magg, Yicheng Long, M. Ryan Corces +7 more

DNMT1 inhibition by pUG-fold quadruplex RNA

RNA(2022)10.1261/rna.079479.122

N/A

0DataRank · unranked

26 citations

Camila I. Sousa, Michael J. Smallegan, Jessica J. Song, Anne R. Gooding, Vignesh Kasinath +3 more

DNMT1 inhibition by pUG-fold quadruplex RNA

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.14.512272

N/A

0DataRank · unranked

2 citations

Camila I. Sousa, Michael J. Smallegan, Jessica J. Song, Anne R. Gooding, Vignesh Kasinath +3 more

Structural basis for inactivation of PRC2 by G-quadruplex RNA

Science(2023)10.1126/science.adh0059

N/A

0DataRank · unranked

68 citations

Anne R. Gooding, Wayne O. Hemphill, Brittney Love, Anne L. Robertson, Liqi Yao +5 more

PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220528120

N/A

0DataRank · unranked

19 citations

Regan Fenske, Anne R. Gooding, Thomas R. Cech, Wayne O. Hemphill

Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220537120

N/A

0DataRank · unranked

12 citations

Calvin K. Voong, Regan Fenske, James A. Goodrich, Thomas R. Cech, Wayne O. Hemphill

Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.17.553776

N/A

0DataRank · unranked

11 citations

Taeyoung Hwang, Anne R. Gooding, Karen J. Goodrich, Skylar D. Hanson, Tenaya K. Vallery +3 more

Structural basis for inactivation of PRC2 by G-quadruplex RNA

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.06.527314

N/A

0DataRank · unranked

9 citations

Anne R. Gooding, Wayne O. Hemphill, Vignesh Kasinath, Thomas R. Cech, Jiarui Song

Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.04.560962

N/A

0DataRank · unranked

5 citations

Jia Z. Woo, Arthur J. Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Thomas R. Cech +3 more

POT1 recruits and regulates CST-Polα/primase at human telomeres

Cell(2024)10.1016/j.cell.2024.05.002

N/A

0DataRank · unranked

28 citations

Hiroyuki Takai, Arthur J. Zaug, Teague C. Dilgen, Thomas R. Cech, Thomas Walz +2 more

Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis

RNA(2024)10.1261/rna.080043.124

N/A

0DataRank · unranked

7 citations

Julia M. Seidel, Thomas R. Cech, Kaitlin Johnson

Transcription factors ERα and Sox2 have differing multiphasic DNA- and RNA-binding mechanisms

RNA(2024)10.1261/rna.080027.124

N/A

0DataRank · unranked

4 citations

Halley R. Steiner, Jackson R. Kominsky, Deborah S. Wuttke, Thomas R. Cech, Wayne O. Hemphill

Telomerase misbehaves after a breakup

Science(2024)10.1126/science.adn7791

N/A

0DataRank · unranked

0 citations

Thomas R. Cech, Nausica Arnoult

Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.18.585577

N/A

0DataRank · unranked

0 citations

Halley R. Steiner, Jackson R. Kominsky, Deborah S. Wuttke, Thomas R. Cech, Wayne O. Hemphill

Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.01.587626

N/A

0DataRank · unranked

0 citations

Julia M. Seidel, Thomas R. Cech, Kaitlin Johnson

DHX36 modulates stress granule assembly independent of recruitment of mRNAs with G-quadruplex sequence motifs

Nucleic Acids Research(2025)10.1093/nar/gkaf938

N/A

0DataRank · unranked

6 citations

Nina Ripin, Thomas R. Cech, Roy Parker, Li Yi Cheng

Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq

Nature Communications(2025)10.1038/s41467-025-56149-6

N/A

0DataRank · unranked

11 citations

Jia Z. Woo, Arthur J. Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Thomas R. Cech +3 more

Rapid dynamics allow the low-abundance RTEL1 helicase to promote telomere replication

Nucleic Acids Research(2025)10.1093/nar/gkaf177

N/A

0DataRank · unranked

3 citations

Erin Taylor, Daniel T. Youmans, Nausica Arnoult, Thomas R. Cech, Guanhui Wu

RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells

Nature Genetics(2020)10.1038/s41588-020-0662-x

N/A

0DataRank · unranked

155 citations

Taeyoung Hwang, Anne R. Gooding, Karen J. Goodrich, John L. Rinn, Thomas R. Cech +1 more

RNA-induced PRC2 inhibition depends on the sequence of bound RNA

Research Square(2025)10.21203/rs.3.rs-7963476/v1

N/A

0DataRank · unranked

0 citations

Jiarui Song, Liqi Yao, Anne R. Gooding, Valentin Thron, Wayne O. Hemphill +3 more