Farshid Guilak

Also affiliated with Regenerative Medicine Institute, Shriners Hospitals for Children - St. Louis, Rockefeller University

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 90 papers. Top paper: “Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway”.

Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway

eLife(2020)10.7554/elife.49558

N/A

1.6DataRank · unranked

72 citations

Catherine C. Gloss, Jeremiah Lorentz, Ruhang Tang, Jonathan M. Brunger, Audrey McAlinden +3 more

The chondrocyte “mechanome”: Activation of the mechanosensitive ion channels TRPV4 and PIEZO1 drives unique transcriptional signatures

The FASEB Journal(2024)10.1096/fj.202400883r

N/A

0.806DataRank · unranked

35 citations

Daniel R. Palmer, Jordan Kassab, Bo Zhang, Farshid Guilak, Robert J. Nims

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes

eLife(2023)10.7554/elife.71154

N/A

0.656DataRank · unranked

23 citations

Grigory Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward +5 more

Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis

Arthritis Research & Therapy(2020)10.1186/s13075-020-02170-7

N/A

0.529DataRank · unranked

33 citations

Sara J. Oswald, Janet L. Huebner, Dianne Little, Virginia B. Kraus, Jing X. Kang +3 more

Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee

Osteoarthritis and Cartilage(2020)10.1016/j.joca.2020.01.015

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0DataRank · unranked

66 citations

Bridgette D. Furman, Jacob Zeitlin, Kelly A. Kimmerling, Chia‐Lung Wu, Farshid Guilak +2 more

NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis

Osteoarthritis and Cartilage(2020)10.1016/j.joca.2020.10.008

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0DataRank · unranked

22 citations

Era Jain, Burçin Yavuz, Thomas McGrath, L. CHEN, Matthew J. Silva +5 more

Transcriptomic analysis of bone and fibrous tissue morphogenesis during digit tip regeneration in the adult mouse

The FASEB Journal(2020)10.1096/fj.202000330r

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0DataRank · unranked

21 citations

Ilan C. Palte, Paul Gontarz, Bo Zhang, Farshid Guilak, Feini Qu

The miRNA‐mRNA interactome of murine induced pluripotent stem cell‐derived chondrocytes in response to inflammatory cytokines

The FASEB Journal(2020)10.1096/fj.202000889r

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0DataRank · unranked

17 citations

Rodrigo Coutinho de Almeida, Y.F. Ramos, Jiehan Li, Ingrid Meulenbelt, Farshid Guilak +1 more

An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties

Biochemical and Biophysical Research Communications(2020)10.1016/j.bbrc.2020.07.016

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0DataRank · unranked

10 citations

Nguyen P.T. Huynh, Alireza Savadipour, Ilan C. Palte, Farshid Guilak, Dakota B. Katz

Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma

UNC Libraries(2020)10.17615/vvhc-xt57

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0DataRank · unranked

11 citations

Yanan Yang, Daniel S. Puperi, Carmen Behrens, Alan R. Burns, Min P. Kim +22 more

Is Obesity a Disease of Stem Cells?

Cell stem cell(2020)10.1016/j.stem.2020.04.019

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0DataRank · unranked

29 citations

Kelsey H. Collins, Natalia S. Harasymowicz, Chia‐Lung Wu, Farshid Guilak, Arin K. Oestreich

Increased susceptibility of Trpv4 -deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet

UNC Libraries(2020)10.17615/apcf-x725

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0DataRank · unranked

3 citations

Timothy M. Griffin, Farshid Guilak, Christopher J. O’Conor, Wolfgang Liedtke

Initial displacement of the intra‐articular surface after articular fracture correlates with PTA in C57BL/6 mice but not “superhealer” MRL/MpJ mice

Journal of Orthopaedic Research®(2020)10.1002/jor.24912

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0DataRank · unranked

1 citations

Bridgette D. Furman, Janet L. Huebner, Kelly A. Kimmerling, Gangadhar M. Utturkar, Cynthia L. Green +4 more

The Mechanobiology of Articular Cartilage: Bearing the Burden of Osteoarthritis

UNC Libraries(2020)10.17615/qrqp-jb86

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0DataRank · unranked

1 citations

Farshid Guilak, Johannah Sanchez‐Adams, Christopher J. O’Conor, Holly A. Leddy, Amy L. McNulty

Adipose Tissue is a Critical Regulator of Osteoarthritis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.134601

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0DataRank · unranked

13 citations

Kristin L. Lenz, Eleanor N. Pollitt, Daniel Ferguson, Irina Hutson, Luke E. Springer +9 more

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.29.069294

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0DataRank · unranked

9 citations

Lara Pferdehirt, Noelani Ho, Alireza Savadipour, Jeremiah Lorentz, Sima Sohi +8 more

Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feed-forward mechanism

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.23.112565

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0DataRank · unranked

1 citations

Robert J. Nims, Alireza Savadipour, Holly A. Leddy, Fang Liu, Amy L. McNulty +4 more

Tendon mechanobiology: Current knowledge and future research opportunities: TENDON MECHANOBIOLOGY

UNC Libraries(2020)10.17615/7yzx-f180

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0DataRank · unranked

0 citations

Steven P. Arnoczky, Farshid Guilak, Albert J. Banes, Michelle E. Wall, Michael Lavagnino +1 more

Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche

UNC Libraries(2020)10.17615/sjvg-xn17

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0DataRank · unranked

0 citations

Lola M. Reid, Eliane Wauthier, Farshid Guilak, Rachael Turner, Sharon R. Lubkin +4 more

Extracellular Calcium Modulates Chondrogenic and Osteogenic Differentiation of Human Adipose-Derived Stem Cells: A Novel Approach for Osteochondral Tissue Engineering Using a Single Stem Cell Source

UNC Libraries(2020)10.17615/62rw-6g17

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0DataRank · unranked

0 citations

Mahsa Mohiti‐Asli, Morgan R. Dent, Farshid Guilak, Elizabeth G. Loboa, Arthi Kannan +2 more

The Relationship of Self-Reported Pain and Functional Impairment to Gait Mechanics in Overweight and Obese Persons With Knee Osteoarthritis

UNC Libraries(2020)10.17615/5nk0-wb92

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0DataRank · unranked

0 citations

Mary Beth Nebel, Jennifer J. Pells, David S. Caldwell, Ershela L. Sims, Farshid Guilak +4 more

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

UNC Libraries(2020)10.17615/g8hj-9y08

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0DataRank · unranked

0 citations

Farshid Guilak, Wolfgang Liedtke

Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis

UNC Libraries(2020)10.17615/zr2b-5e81

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0DataRank · unranked

0 citations

Wolfgang Liedtke, Christopher J. O’Conor, Chia‐Lung Wu, Farshid Guilak, Isaura Rigo +6 more

Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2001611118

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0DataRank · unranked

256 citations

Robert J. Nims, Alireza Savadipour, Qiaojuan Zhang, Holly A. Leddy, Fang Liu +5 more

Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis

Nature Communications(2021)10.1038/s41467-020-20598-y

N/A

0DataRank · unranked

185 citations

Amanda Dicks, Nancy Steward, Ruhang Tang, Dakota B. Katz, Yun‐Rak Choi +2 more

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Science Advances(2021)10.1126/sciadv.abd9858

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0DataRank · unranked

88 citations

Lara Pferdehirt, Noelani Ho, Alireza Savadipour, Jeremiah Lorentz, Sima Sohi +8 more

Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues

International Journal of Molecular Sciences(2021)10.3390/ijms22052716

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0DataRank · unranked

68 citations

Anthony J. Hayes, James Melrose, Farshid Guilak

A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery

Science Advances(2021)10.1126/sciadv.abj1414

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0DataRank · unranked

49 citations

Kelsey H. Collins, Luke E. Springer, Lara Pferdehirt, Alison K. Ross, Chia‐Lung Wu +6 more

Immunoengineering the next generation of arthritis therapies

Acta Biomaterialia(2021)10.1016/j.actbio.2021.03.062

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0DataRank · unranked

44 citations

Robert J. Nims, Lara Pferdehirt, Kelsey H. Collins, Natalia S. Harasymowicz, Sara J. Oswald +3 more

Single‐cell RNA sequencing reveals the induction of novel myeloid and myeloid‐associated cell populations in visceral fat with long‐term obesity

The FASEB Journal(2021)10.1096/fj.202001970r

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0DataRank · unranked

43 citations

Neda Rashidi, Alireza Savadipour, Chia‐Lung Wu, Ruhang Tang, John Bramley +3 more

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

Cell and Tissue Research(2021)10.1007/s00441-021-03498-5

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0DataRank · unranked

43 citations

Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G. H. H. Nelissen +7 more

Transient Receptor Potential Vanilloid 4 as a Regulator of Induced Pluripotent Stem Cell Chondrogenesis

Stem Cells(2021)10.1002/stem.3440

N/A

0DataRank · unranked

36 citations

Holly A. Leddy, Daniel Palmer, Chia‐Lung Wu, Wolfgang Liedtke, Farshid Guilak +1 more

Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels

Connective Tissue Research(2021)10.1080/03008207.2020.1871475

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0DataRank · unranked

35 citations

Robert J. Nims, Dakota B. Katz, Farshid Guilak, Alireza Savadipour

Mechanogenetics: harnessing mechanobiology for cellular engineering

Current Opinion in Biotechnology(2021)10.1016/j.copbio.2021.09.011

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0DataRank · unranked

31 citations

Lara Pferdehirt, Farshid Guilak, Robert J. Nims

Fresh Osteochondral and Chondral Allograft Preservation and Storage Media: A Systematic Review of the Literature

The American Journal of Sports Medicine(2021)10.1177/03635465211016832

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0DataRank · unranked

26 citations

Farshid Guilak, Robert L. Sah, William D. Bugbee, Suzanne M. Tabbaa

Taxonomic changes in the gut microbiota are associated with cartilage damage independent of adiposity, high fat diet, and joint injury

Scientific Reports(2021)10.1038/s41598-021-94125-4

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0DataRank · unranked

20 citations

Drew J. Schwartz, Kristin L. Lenz, Charles Harris, Farshid Guilak, Kelsey H. Collins

Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model

European Cells and Materials(2021)10.22203/ecm.v041a04

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0DataRank · unranked

19 citations

ML Sennett, JM Friedman, BS Ashley, BD Stoeckl, Jay Patel +14 more

Functional tissue engineering of articular cartilage for biological joint resurfacing—The 2021 Elizabeth Winston Lanier Kappa Delta Award

Journal of Orthopaedic Research®(2021)10.1002/jor.25223

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0DataRank · unranked

8 citations

Bradley T. Estes, Franklin T. Moutos, Farshid Guilak

The deformation behavior and mechanical properties of chondrocytes in articular cartilage

UNC Libraries(2021)10.17615/2ed9-w003

N/A

0DataRank · unranked

0 citations

Greta M. Lee, Wendy R. Jones, H.Ping Ting-Beall, Farshid Guilak

Leptin mediates the regulation of muscle mass and strength by adipose tissue

The Journal of Physiology(2022)10.1113/jp283034

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0DataRank · unranked

53 citations

Chang Gui, Erica V. Ely, Kristin L. Lenz, Charles Harris, Farshid Guilak +2 more

Engineering Hyaluronic Acid for the Development of New Treatment Strategies for Osteoarthritis

International Journal of Molecular Sciences(2022)10.3390/ijms23158662

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0DataRank · unranked

53 citations

Farshid Guilak, Yu Seon Kim

Modulation of TRPV4 protects against degeneration induced by sustained loading and promotes matrix synthesis in the intervertebral disc

The FASEB Journal(2022)10.1096/fj.202201388r

N/A

0DataRank · unranked

33 citations

Alireza Savadipour, Akila Anandarajah, Leanne E. Iannucci, Spencer P. Lake, Farshid Guilak +2 more

Chondrogenic Differentiation of Human-Induced Pluripotent Stem Cells

Methods in molecular biology(2022)10.1007/978-1-0716-2839-3_8

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0DataRank · unranked

14 citations

Nancy Steward, Farshid Guilak, Chia‐Lung Wu, Amanda Dicks

In vitro analysis of genome‐engineered muscle‐derived stem cells for autoregulated anti‐inflammatory and antifibrotic activity

Journal of Orthopaedic Research®(2022)10.1002/jor.25311

N/A

0DataRank · unranked

7 citations

Ping Guo, Aiping Lu, Mathew Huard, Farshid Guilak, Johnny Huard +1 more

Trimming the fat — is leptin crosstalk the link between obesity and osteoarthritis?

Osteoarthritis and Cartilage(2022)10.1016/j.joca.2022.10.011

N/A

0DataRank · unranked

6 citations

Farshid Guilak, Kelsey H. Collins

A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.19.520461

N/A

0DataRank · unranked

2 citations

Zainab Harissa, Shaunak Adkar, Amanda Dicks, Ghazaleh Hajmousa, Nancy Steward +9 more

Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.26.509507

N/A

0DataRank · unranked

1 citations

Sulbha Choudhari, Chia‐Lung Wu, Karen Abramson, David L. Corcoran, Simon G. Gregory +4 more

Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221958120

N/A

0DataRank · unranked

80 citations

Robert J. Nims, Neda Rashidi, Jaquelin M. Garcia‐Castorena, Ruhang Tang, Gabrielle K. Marushack +4 more

The role of PIEZO ion channels in the musculoskeletal system

American Journal of Physiology-Cell Physiology(2023)10.1152/ajpcell.00544.2022

N/A

0DataRank · unranked

75 citations

D. Palmer, Erica V. Ely, Kelsey H. Collins, Jaquelin M. Garcia‐Castorena, Zainab Harissa +6 more

Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks

Nature Communications(2023)10.1038/s41467-023-42056-1

N/A

0DataRank · unranked

36 citations

Dharshika RJ Pathiranage, Beatriz Baño‐Otálora, Anna Paszek, Natalie Rogers, Cátia F. Gonçalves +8 more

Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine Therapy

Gels(2023)10.3390/gels9020169

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0DataRank · unranked

22 citations

Lara Pferdehirt, Leila Saleh, Alireza Savadipour, Luke E. Springer, Kristin L. Lenz +5 more

TRPV4 differentially controls inflammatory cytokine networks during static and dynamic compression of the intervertebral disc

JOR Spine(2023)10.1002/jsp2.1282

N/A

0DataRank · unranked

20 citations

Alireza Savadipour, C. González, Farshid Guilak, Simon Y. Tang, Garrett W. D. Easson

Aging and obesity prime the methylome and transcriptome of adipose stem cells for disease and dysfunction

The FASEB Journal(2023)10.1096/fj.202201413r

N/A

0DataRank · unranked

7 citations

Sulbha Choudhari, Chia‐Lung Wu, Karen Abramson, David L. Corcoran, Simon G. Gregory +4 more

Tendon‐derived matrix crosslinking techniques for electrospun multi‐layered scaffolds

Journal of Biomedical Materials Research Part A(2023)10.1002/jbm.a.37588

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0DataRank · unranked

2 citations

Paula Sarmiento, Kentaro Umemori, Farshid Guilak, Dianne Little, Thomas L. Jenkins

Hyper-physiologic mechanical cues, as an osteoarthritis disease relevant environmental perturbation, cause a critical shift in set-points of methylation at transcriptionally active CpG sites in neo-cartilage organoids

Research Square(2023)10.21203/rs.3.rs-3568544/v1

N/A

0DataRank · unranked

1 citations

Amanda Dicks, Zainab Harissa, Rob G. H. H. Nelissen, Ghazaleh Hajmousa, Y.F. Ramos +4 more

Designer fat cells: adipogenic differentiation of CRISPR-Cas9 genome-engineered induced pluripotent stem cells

European Cells and Materials(2023)10.22203/ecm.v046a09

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0DataRank · unranked

0 citations

Ashlyn T Kapinski, S G Paradi, Ruhang Tang, Farshid Guilak, K H Collins +1 more

Gene therapy for fat-1 prevents obesity-induced metabolic dysfunction, cellular senescence, and osteoarthritis

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2402954121

N/A

0DataRank · unranked

32 citations

Natalia S. Harasymowicz, Chia‐Lung Wu, Yun‐Rak Choi, Kristin L. Lenz, Sara J. Oswald +2 more

A Damaging COL6A3 Variant Alters the MIR31HG ‐Regulated Response of Chondrocytes in Neocartilage Organoids to Hyperphysiologic Mechanical Loading

Advanced Science(2024)10.1002/advs.202400720

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0DataRank · unranked

18 citations

Zainab Harissa, Giorgia Mazzini, Shaunak Adkar, Amanda Dicks, Ghazaleh Hajmousa +10 more

Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery

Arthritis Research & Therapy(2024)10.1186/s13075-024-03425-3

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0DataRank · unranked

13 citations

Amanda Cimino, Kristin L. Lenz, Luke E. Springer, Kelsey H. Collins, Natalia S. Harasymowicz +4 more

Distinct patterns of cytokines, chemokines, and growth factors in synovial fluid after ACL injury in comparison to osteoarthritis

Journal of Orthopaedic Research®(2024)10.1002/jor.25794

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0DataRank · unranked

12 citations

Lei Cai, Nobuaki Chinzei, E. Schmidt, Omer Yousuf, Farshid Guilak +2 more

Mechanobiology of Hyaluronan: Connecting Biomechanics and Bioactivity in Musculoskeletal Tissues

Annual Review of Biomedical Engineering(2024)10.1146/annurev-bioeng-073123-120541

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10 citations

Farshid Guilak, Robert L. Sah, Sarah Calve, Deva D. Chan

PIEZO1-mediated calcium influx transiently alters nuclear mechanical properties via actin remodeling in chondrocytes

Biochemical and Biophysical Research Communications(2024)10.1016/j.bbrc.2024.151135

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0DataRank · unranked

10 citations

Rosa Riester, Miranda Gamino-Ornelas, Nikitha Ada, Farshid Guilak, Marina Danalache +1 more

Mode of injury and level of synovitis alter inflammatory chondrocyte gene expression and associated pathways

Scientific Reports(2024)10.1038/s41598-024-71964-5

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8 citations

Daniel J. Cunningham, Bridgette D. Furman, John S. Yi, Jonathan M. Brunger, Virginia B. Kraus +4 more

Excess Intramyocellular Lipid Does Not Affect Muscle Fiber Biophysical Properties in Mice or People With Metabolically Abnormal Obesity

Diabetes(2024)10.2337/db23-0991

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0DataRank · unranked

5 citations

Kelsey H. Collins, J Ferey, Alan Fappi, Jeremy J. McCormick, Bettina Mittendorfer +3 more

Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc

JOR Spine(2024)10.1002/jsp2.1362

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0DataRank · unranked

6 citations

Farshid Guilak, James Melrose

Maternal high‐fat high‐sugar diet impairs bone quality and strength but not cartilage in aging mice

Journal of Orthopaedic Research®(2024)10.1002/jor.25980

N/A

0DataRank · unranked

6 citations

Natalia S. Harasymowicz, Alireza Savadipour, Zainab Harissa, Neda Rashidi, Meredith K. Luhmann +4 more

Genetically Engineered Macrophages Derived from iPSCs for Self-Regulating Delivery of Anti-Inflammatory Biologic Drugs

Journal of Tissue Engineering and Regenerative Medicine(2024)10.1155/2024/6201728

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3 citations

Farshid Guilak, Molly Klimak

Hyper-physiologic mechanical cues, as an osteoarthritis disease-relevant environmental perturbation, cause a critical shift in set points of methylation at transcriptionally active CpG sites in neo-cartilage organoids

Clinical Epigenetics(2024)10.1186/s13148-024-01676-0

N/A

0DataRank · unranked

2 citations

Amanda Dicks, Zainab Harissa, Rob G. H. H. Nelissen, Ghazaleh Hajmousa, Y.F. Ramos +4 more

PIEZO1-Mediated Mechanotransduction Regulates Collagen Synthesis on Nanostructured 2D and 3D Models of Fibrosis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.30.601386

N/A

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2 citations

Natalia S. Harasymowicz, Alireza Savadipour, Nancy Steward, Ruhang Tang, Sara J. Oswald +2 more

Engineered Self-Regulating Macrophages for Targeted Anti-inflammatory Drug Delivery

Research Square(2024)10.21203/rs.3.rs-4385938/v1

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0DataRank · unranked

1 citations

Amanda Cimino, Kristin L. Lenz, Luke E. Springer, Kelsey H. Collins, Natalia S. Harasymowicz +4 more

Current cutting-edge omics techniques on musculoskeletal tissues and diseases

Bone Research(2025)10.1038/s41413-025-00442-z

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22 citations

Fang Ting Liang, Renpeng Zhou, Lutian Yao, Sade W. Clayton, Samantha Muscat +12 more

A synthetic chronogenetic gene circuit for programmed circadian drug delivery

Nature Communications(2025)10.1038/s41467-025-56584-5

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19 citations

Anna R. Damato, Kristin L. Lenz, Maria F. Gonzalez-Aponte, Daniel Palmer, Qing‐Jun Meng +3 more

Activation of the mechanosensitive ion channels TRPV4 and PIEZO1 downregulates key regulatory systems in the chondrocyte mechanome

Connective Tissue Research(2025)10.1080/03008207.2025.2498512

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8 citations

Robert J. Nims, Bo Zhang, Farshid Guilak, Daniel R. Palmer

Injury and obesity differentially and synergistically induce dysregulation of synovial immune cells in osteoarthritis

Annals of the Rheumatic Diseases(2025)10.1016/j.ard.2025.03.001

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15 citations

Zainab Harissa, Neda Rashidi, Kristin L. Lenz, Ruhang Tang, Farshid Guilak +1 more

Transformative approaches for effective clinical trials to reduce the disease burden of osteoarthritis

Seminars in Arthritis and Rheumatism(2025)10.1016/j.semarthrit.2025.152652

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12 citations

Marc C. Hochberg, Daniel White, Scott A. Rodeo, Johnny Huard, Shane A. Shapiro +3 more

Chondrocyte-specific knockout of Piezo1 and Piezo2 protects against post-traumatic osteoarthritis structural damage and pain in mice

Arthritis Research & Therapy(2025)10.1186/s13075-025-03620-w

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8 citations

Kristin L. Lenz, Sophie G. Paradi, Seth Ack, Abraham Behrmann, Sarah Dunivan +6 more

Programmable chronogenetic gene circuits for self-regulated circadian delivery of biologic drugs

Journal of Controlled Release(2025)10.1016/j.jconrel.2025.113959

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7 citations

Fiona Pat, Omolabake Oyebamiji, Lara Pferdehirt, Christine T. N. Pham, Erik D. Herzog +2 more

Polyunsaturated fatty acids suppress PIEZO ion channel mechanotransduction in articular chondrocytes

The FASEB Journal(2025)10.1096/fj.202400544rr

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6 citations

Alireza Savadipour, Ruhang Tang, Jaquelin M. Garcia‐Castorena, Neda Rashidi, Robert J. Nims +4 more

Skeletal dysplasia-causing mutations in TRPV4 alter the chondrocyte transcriptomic response to mechanical loading

American Journal of Physiology-Cell Physiology(2025)10.1152/ajpcell.01066.2024

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6 citations

Yun Sung Kim, Amanda Dicks, Nancy Steward, Farshid Guilak, Zainab Harissa

Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways

Journal of Biological Engineering(2025)10.1186/s13036-025-00519-7

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6 citations

Fiona Pat, Omolabake Oyebamiji, Christine T. N. Pham, Erik D. Herzog, Farshid Guilak +1 more

Digit regeneration is expedited in LG/J healer mice compared to SM/J non-healer mice

npj Regenerative Medicine(2025)10.1038/s41536-025-00399-x

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4 citations

Kristin L. Lenz, Gwendalyn L. Krekeler, Xin Duan, Muhammad Farooq, Farshid Guilak +1 more

PIEZO mechanosensitivity in chondrocytes is differentially modulated by L-type and T-type voltage-sensitive ion channels

Osteoarthritis and Cartilage Open(2025)10.1016/j.ocarto.2025.100710

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0DataRank · unranked

2 citations

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bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.22.655585

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0DataRank · unranked

1 citations

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bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.06.663396

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0DataRank · unranked

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0DataRank · unranked

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Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2021096118

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0DataRank · unranked

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0DataRank · unranked

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0DataRank · unranked

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Stem Cell Research & Therapy(2020)10.1186/s13287-020-01597-8

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Science Advances(2020)10.1126/sciadv.aaz7492

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0DataRank · unranked

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