Jeffrey T. Safrit

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques”.

Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques

Journal of Virology(2020)10.1128/jvi.00755-20

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1.3DataRank · unranked

58 citations

Andrew Kam Ho Wong, Erick White, Diane G. Carnathan, John H. Lee, Jeffrey T. Safrit +5 more

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

PLoS Pathogens(2020)10.1371/journal.ppat.1008339

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0.626DataRank · unranked

64 citations

Jhomary Molden, Kathleen Busman‐Sahay, Shaheed Abdulhaqq, Helen L. Wu, Whitney C. Weber +17 more

Safety and Virologic Impact of Haploidentical NK Cells Plus Interleukin 2 or N-803 in HIV Infection

The Journal of Infectious Diseases(2024)10.1093/infdis/jiad578

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0.520DataRank · unranked

20 citations

Joshua Rhein, Zachary Davis, Sarah Cooley, David H. McKenna, Jodi Anderson +11 more

Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8+T Cell Function Reveals Multiple Limitations of Class I-Selective Histone Deacetylase Inhibitors during HIV-1 Latency Reversal

Journal of Virology(2020)10.1128/jvi.01845-19

N/A

0.489DataRank · unranked

25 citations

Chase D. McCann, Ali Danesh, Szu-Han Huang, Dean Magat, Yanqin Ren +12 more

Impact of the IL-15 superagonist N-803 on lymphatic reservoirs of HIV

JCI Insight(2025)10.1172/jci.insight.190831

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0.348DataRank · unranked

9 citations

Jeffrey G. Chipman, Gregory J. Beilman, Ross Cromarty, Kevin Escandón-Vargas, Jodi Anderson +18 more

Control of Simian Immunodeficiency Virus Infection in Prophylactically Vaccinated, Antiretroviral Treatment-Naive Macaques Is Required for the Most Efficacious CD8 T Cell Response during Treatment with the Interleukin-15 Superagonist N-803

Journal of Virology(2022)10.1128/jvi.01185-22

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0.345DataRank · unranked

9 citations

Alexis J. Balgeman, Olivia E. Harwood, Ryan V. Moriarty, Jeffrey T. Safrit, Andrea M. Weiler +3 more

SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques

PLoS Pathogens(2025)10.1371/journal.ppat.1012863

N/A

0.241DataRank · unranked

4 citations

Tzoalli Anaya, Alexis C. King, Kedan Endrias, Anne Hébert, Alison L. Hill +11 more

Control of SIV infection in prophylactically vaccinated, ART-naïve macaques is required for the most efficacious CD8 T cell response during treatment with the IL-15 superagonist N-803

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.02.494515

N/A

0.104DataRank · unranked

1 citations

Alexis J. Balgeman, Olivia E. Harwood, Ryan V. Moriarty, Jeffrey T. Safrit, Andrea M. Weiler +3 more

Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques

Science(2024)10.1126/science.adf7966

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0DataRank · unranked

30 citations

Jina Lee, Christa E. Osuna, Pratik Vikhe, Dane Schalk, Elsa Chen +22 more

AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques

UNC Libraries(2024)10.17615/peem-q524

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0DataRank · unranked

0 citations

David S. Margolis, Vidisha Singh, Sherrie Jean, Margaret Neja, Guido Silvestri +24 more

Therapeutic CD8 + T cell tissue retention and immunomodulation during ART interruption fail to prevent SIV rebound

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2501037122

N/A

0DataRank · unranked

5 citations

Sadia Samer, Elise G. Viox, Kevin Nguyen, Claire Deléage, Leticia Kuri-Cervantes +10 more

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Nature(2020)10.1038/s41586-020-1946-0

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0DataRank · unranked

196 citations

Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp +23 more

Pre-treatment Microbiome Diversity and Function is associated with Expansion of Cytotoxic and Regulatory Immune Populations after N-803 treatment in People with HIV

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.01.679827

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0DataRank · unranked

3 citations

Ross Cromarty, Christopher M. Basting, Jodi Anderson, Ty Schroeder, Kevin Escandón-Vargas +12 more

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Nature(2020)10.1038/s41586-020-2002-9

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0DataRank · unranked

28 citations

Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp +23 more

Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021

Nature Medicine(2021)10.1038/s41591-021-01590-5

N/A

0DataRank · unranked

372 citations

Nancie M. Archin, Paula M. Cannon, Simon Collins, R. Brad Jones, Marein A.W.P. de Jong +74 more

Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors and in vivo survival of xenografted immunodeficient NSG mice

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2020-002267

N/A

0DataRank · unranked

41 citations

Gaurav Nayyar, Susiyan Jiang, Jeremy Rosenblum, Patrick Soon‐Shiong, Jeffrey T. Safrit +3 more

Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge

Frontiers in Immunology(2021)10.3389/fimmu.2021.729837

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0DataRank · unranked

29 citations

Jeffrey T. Safrit, Mohit S. Verma, Adrian Rice, Peter A. Sieling, Lise Zakin +20 more

Transient T Cell Expansion, Activation, and Proliferation in Therapeutically Vaccinated Simian Immunodeficiency Virus-Positive Macaques Treated with N-803

Journal of Virology(2022)10.1128/jvi.01424-22

N/A

0DataRank · unranked

4 citations

Alexis J. Balgeman, Abigail J. Weaver, Amy Ellis, Andrea M. Weiler, Katrina N. Erickson +10 more

IL-15 Superagonist N-803 Enhances IFN-γ Production of MAIT Cells in SIV + Macaques

Infection and Immunity(2022)10.1128/iai.00259-22

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0DataRank · unranked

2 citations

Alexis J. Balgeman, Nadean M. Kannal, Karigynn Hansen Chaimson, Anna Batchenkova, Jeffrey T. Safrit +2 more

AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques

Nature Medicine(2023)10.1038/s41591-023-02570-7

N/A

0DataRank · unranked

47 citations

Sophia Sukkestad, Anna M. Horner, Margaret Neja, Zain Siddiqi, Chevaughn Waller +24 more