Hideki Aihara

Also affiliated with University of Minnesota System, University of Minnesota Medical Center, Institute of Molecular Biology and Biophysics

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 56 papers. Top paper: “Structural Basis for Human Receptor Recognition by SARS-CoV-2 Omicron Variant BA.1”.

Structural Basis for Human Receptor Recognition by SARS-CoV-2 Omicron Variant BA.1

Journal of Virology(2022)10.1128/jvi.00249-22

N/A

2.4DataRank · unranked

72 citations

Ke Shi, Gang Ye, Wei Zhang, Hideki Aihara, Fang Li +1 more

Structural basis of receptor recognition by SARS-CoV-2

Nature(2020)10.1038/s41586-020-2179-y

N/A

1.2DataRank · unranked

4071 citations

Gang Ye, Ke Shi, Yushun Wan, Chuming Luo, Hideki Aihara +4 more

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

iScience(2023)10.1016/j.isci.2023.107823

N/A

0.581DataRank · unranked

18 citations

Erik A. Toso, Elizabeth T. Ener, Micah D. Gearhart, Lulu Yin, Felipe F. Lüttmann +6 more

Selective N‐Terminal BET Bromodomain Inhibitors by Targeting Non‐Conserved Residues and Structured Water Displacement**

Angewandte Chemie International Edition(2020)10.1002/anie.202008625

N/A

0.574DataRank · unranked

45 citations

Anand Divakaran, Anil K. Pandey, Jorden A. Johnson, Huda Zahid, Zachariah J. Hoell +6 more

The Development of a Novel Nanobody Therapeutic for SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.17.386532

N/A

0.489DataRank · unranked

25 citations

Joseph P. Gallant, Christopher Massey, Ke Shi, Wanbo Tai, Jian Zheng +14 more

A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid RNA-binding domain

Nucleic Acids Research(2024)10.1093/nar/gkae874

N/A

0.457DataRank · unranked

20 citations

Christopher Belica, Joseph A. Rollie, William L. Brown, Seyed Arad Moghadasi, Ke Shi +4 more

Current Progress in the Structural and Biochemical Characterization of Proteins Involved in the Assembly of Lipopolysaccharide

International Journal of Microbiology(2018)10.1155/2018/5319146

N/A

0.442DataRank · unranked

18 citations

Hideki Aihara, Heather O. Bohl

Targeting N-Myc in Neuroblastoma with Selective Aurora Kinase A Degraders

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.09.487756

N/A

0.376DataRank · unranked

6 citations

Ramkumar Moorthy, Özlem Demir, Zachary D. Baker, Jordan A. Naumann, Katherine F. M. Jones +10 more

Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107502

N/A

0.360DataRank · unranked

10 citations

Dustin Hicks, Ke Shi, Nicholas H. Moeller, B. Hoppe, Eric W. Lake +5 more

HK022 bacteriophage Integrase mediated RMCE as a potential tool for human gene therapy

Nucleic Acids Research(2020)10.1093/nar/gkaa1140

N/A

0.330DataRank · unranked

8 citations

Hala Kassis, Suha Abd Elkader, Natasha Gritsenko, Alessio D. Nahmad, Hodaya Shir +7 more

Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan

Structure(2024)10.1016/j.str.2024.08.019

N/A

0.208DataRank · unranked

3 citations

Amanda N Hayward, Adam T. Smiley, Ke Shi, Matthew R. Pawlak, Eric J. Aird +7 more

HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.01.478508

N/A

0.165DataRank · unranked

2 citations

Huixin Yang, Ke Shi, Raffaele Coray, Guichuan Yu, William G. Arndt +8 more

Molecular determinants for Rous sarcoma virus intasome assemblies involved in retroviral integration

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104730

N/A

0.165DataRank · unranked

2 citations

Ke Shi, Hideki Aihara, Duane P. Grandgenett, Krishan K. Pandey, Sibes Bera

Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.04.487063

N/A

0.165DataRank · unranked

2 citations

AN Hayward, AT Smiley, K. Shi, Matthew R. Pawlak, Eric J. Aird +7 more

Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.01.278671

N/A

0.104DataRank · unranked

1 citations

Mo Houtti, L.A. Litzau, Eric J. Aird, Blake A. Everett, Andrew T. Nelson +8 more

RADD: A real-time FRET-based biochemical assay for DNA deaminase studies

Methods in enzymology on CD-ROM/Methods in enzymology(2024)10.1016/bs.mie.2024.08.001

N/A

0.104DataRank · unranked

1 citations

Patricia C. Hernández, Michael A. Carpenter, Yanjun Chen, William L. Brown, Reuben S. Harris +2 more

Molecular Basis for Rep HUH‐endonuclease Mediated Protein‐DNA Bioconjugation

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.03221

N/A

0DataRank · unranked

0 citations

Mo Houtti, L.A. Litzau, Eric J. Aird, Blake A. Everett, Andrew T. Nelson +8 more

Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2106379119

N/A

0DataRank · unranked

194 citations

Ke Shi, Özlem Demir, Christopher Belica, Surajit Banerjee, Lulu Yin +4 more

Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2206509119

N/A

0DataRank · unranked

53 citations

Ke Shi, Qibin Geng, Gang Ye, Hideki Aihara, Fang Li +1 more

Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells

mBio(2022)10.1128/mbio.00784-22

N/A

0DataRank · unranked

39 citations

Morgan A. Esler, Yuka Otsuka, Jordan T. Becker, Sofia N. Moraes, Constance B. Anderson +12 more

SARS-CoV-2 nsp14 Exoribonuclease Removes the Natural Antiviral 3′-Deoxy-3′,4′-didehydro-cytidine Nucleotide from RNA

Viruses(2022)10.3390/v14081790

N/A

0DataRank · unranked

16 citations

Kellan T. Passow, Daniel A. Harki, Hideki Aihara, Nicholas H. Moeller

Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddA

Research Square(2022)10.21203/rs.3.rs-2031914/v1

N/A

0DataRank · unranked

1 citations

Lulu Yin, Ke Shi, Hideki Aihara

Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddA

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-01034-3

N/A

0DataRank · unranked

26 citations

Ke Shi, Hideki Aihara, Lulu Yin

Structural evolution of SARS-CoV-2 omicron in human receptor recognition

Journal of Virology(2023)10.1128/jvi.00822-23

N/A

0DataRank · unranked

23 citations

Ke Shi, Qibin Geng, Morgan Herbst, Michael Wang, Linfen Huang +5 more

HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168143

N/A

0DataRank · unranked

14 citations

Huixin Yang, Ke Shi, Raffaele Coray, Guichuan Yu, William G. Arndt +8 more

The crystal structure of the human smacovirus 1 Rep domain

Acta Crystallographica Section F Structural Biology Communications(2023)10.1107/s2053230x23009536

N/A

0DataRank · unranked

1 citations

Ke Shi, Amy Dao, Jacob Rugloski, Kassidy J. Tompkins, Hideki Aihara +3 more

Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.23.554512

N/A

0DataRank · unranked

5 citations

Colin T. Pierce, Bo Guan, Javier Iglesias‐Fernández, Huey-Yee Lim, L. Greenberg +8 more

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.21.524976

N/A

0DataRank · unranked

0 citations

Erik A. Toso, Elizabeth T. Ener, Micah D. Gearhart, Lulu Yin, Felipe F. Lüttmann +6 more

Molecular determinants for Rous sarcoma virus intasome assemblies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.02.528060

N/A

0DataRank · unranked

0 citations

Ke Shi, Hideki Aihara, Duane P. Grandgenett, Krishan K. Pandey, Sibes Bera

Understanding ATP binding to DosS catalytic domain with a short ATP-lid

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.29.542785

N/A

0DataRank · unranked

0 citations

Peter Windsor, Elizabeth M. Smithwick, Ke Shi, Hideki Aihara, Anoop R. Damodaran +2 more

Structural basis for raccoon dog receptor recognition by SARS-CoV-2

PLoS Pathogens(2024)10.1371/journal.ppat.1012204

N/A

0DataRank · unranked

9 citations

Ke Shi, Alise Mendoza, Fan Bu, Wei Zhang, Hideki Aihara +2 more

Structural basis for mouse receptor recognition by bat SARS2-like coronaviruses

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2322600121

N/A

0DataRank · unranked

6 citations

Ke Shi, Fu‐Chun Hsueh, Alise Mendoza, Gang Ye, Linfen Huang +4 more

A real-time biochemical assay for quantitative analyses of APOBEC-catalyzed DNA deamination

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107410

N/A

0DataRank · unranked

6 citations

Michael A. Carpenter, Yanjun Chen, William L. Brown, Nicholas H. Moeller, Ian T Boylan +3 more

Structural basis of divergent substrate recognition and inhibition of human neurolysin

Scientific Reports(2024)10.1038/s41598-024-67639-w

N/A

0DataRank · unranked

2 citations

Sounak Bagchi, Jordis Bickel, Shiva Hadi Esfahani, Lulu Yin, Tiffany Cheng +3 more

Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders

Cell chemical biology(2025)10.1016/j.chembiol.2024.12.006

N/A

0DataRank · unranked

23 citations

Ramkumar Moorthy, Laura Hirsch, Özlem Demir, Zachary D. Baker, Jordan A. Naumann +12 more

The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors

Nature Communications(2025)10.1038/s41467-025-66967-3

N/A

0DataRank · unranked

3 citations

Eric W. Lake, Kendahl L. Ott, Stella Priyanka, Sasha Celeda, Jayden L. West +9 more

Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA

Nature Communications(2025)10.1038/s41467-025-63943-9

N/A

0DataRank · unranked

1 citations

Yanjun Chen, Ke Shi, Emilia Barreto-Durán, Reuben S. Harris, Hideki Aihara +1 more

Development of cell-active BRD4-D1 selective inhibitors to decode the role of BET proteins in LPS-mediated liver inflammation

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118519

N/A

0DataRank · unranked

1 citations

Luke C. Doskey, Sai Giridhar Sarma Kandanur, Nora R. Vail, Erika R. Roderick, Elliott Peterson +8 more

Crystal structure of a seven-substitution mutant of hydroxynitrile lyase from rubber tree

Acta Crystallographica Section F Structural Biology Communications(2025)10.1107/s2053230x25007034

N/A

0DataRank · unranked

1 citations

L. Greenberg, Meghan E. Walsh, Ke Shi, D. A. Magee, Hideki Aihara +4 more

Rational design of tertiary coordination sphere of a heme-based sensor for two-orders enhanced oxygen affinity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.27.656425

N/A

0DataRank · unranked

0 citations

Eaindra Yee, Rahul L. Khade, Murphi T. Williams, Elizabeth A. Apiche, R. Hunter Wilson +7 more

A real-time biochemical assay for quantitative analyses of APOBEC-catalyzed DNA deamination

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.11.593688

N/A

0DataRank · unranked

1 citations

Michael A. Carpenter, Yanjun Chen, William L. Brown, Nicholas H. Moeller, Ian T. Boylan +3 more

Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering

Nucleic Acids Research(2020)10.1093/nar/gkaa1248

N/A

0DataRank · unranked

52 citations

Mo Houtti, L.A. Litzau, Eric J. Aird, Blake A. Everett, Andrew T. Nelson +8 more

Structural basis of host protein hijacking in human T-cell leukemia virus integration

Nature Communications(2020)10.1038/s41467-020-16963-6

N/A

0DataRank · unranked

42 citations

Ke Shi, Daniel J. Salamango, Nicholas H. Moeller, Krishan K. Pandey, Sibes Bera +9 more

DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD

The FASEB Journal(2020)10.1096/fj.201902696

N/A

0DataRank · unranked

29 citations

Jon Ashley, Ke Shi, Adeline Stiefvater, Michael Kyba, Michael Sinnreich +3 more

Structural basis of superinfection exclusion by bacteriophage T4 Spackle

Communications Biology(2020)10.1038/s42003-020-01412-3

N/A

0DataRank · unranked

28 citations

Justin Oakland, Fredy Kurniawan, Nicholas H. Moeller, Surajit Banerjee, Hideki Aihara +1 more

Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase

Scientific Reports(2020)10.1038/s41598-019-56825-w

N/A

0DataRank · unranked

5 citations

Ke Shi, Timsi Rao, Surajit Banerjee, Hideki Aihara, Na Li

Selective N‐Terminal BET Bromodomain Inhibitors by Targeting Non‐Conserved Residues and Structured Water Displacement**

Angewandte Chemie(2020)10.1002/ange.202008625

N/A

0DataRank · unranked

2 citations

Anand Divakaran, Anil K. Pandey, Jorden A. Johnson, Huda Zahid, Zachariah J. Hoell +6 more

Structural basis for receptor recognition by the novel coronavirus from Wuhan

Research Square(2020)10.21203/rs.2.24749/v1

N/A

0DataRank · unranked

49 citations

Gang Ye, Ke Shi, Yushun Wan, Chuming Luo, Hideki Aihara +4 more

The development of Nanosota-1 as anti-SARS-CoV-2 nanobody drug candidates

eLife(2021)10.7554/elife.64815

N/A

0DataRank · unranked

62 citations

Joseph P. Gallant, Jian Zheng, Christopher Massey, Ke Shi, Wanbo Tai +10 more

New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01294

N/A

0DataRank · unranked

35 citations

Caroline R. Buchholz, Manjulata Singh, Michael F. Ciccone, A. Chan, Stanley Nithianantham +8 more

Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening

Nature Communications(2021)10.1038/s41467-021-21878-x

N/A

0DataRank · unranked

40 citations

Wendy Leung, Megan Schmit, Jacob P. Matson, Lulu Yin, Marissa K. Oram +21 more

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

Nature Communications(2021)10.1038/s41467-021-27611-y

N/A

0DataRank · unranked

38 citations

Eric W. Lake, Gihan S. Gunaratne, Joseph P. Gallant, M. Fernie, Austin J. Robertson +16 more

4-Methyl-1,2,3-Triazoles as N-Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00933

N/A

0DataRank · unranked

36 citations

Angela S. Carlson, Mary A. Schleiff, Anand Divakaran, Jorden A. Johnson, Caroline R. Buchholz +9 more

Soluble Methane Monooxygenase Component Interactions Monitored by 19F NMR

Biochemistry(2021)10.1021/acs.biochem.1c00293

N/A

0DataRank · unranked

13 citations

R. Banerjee, Ke Shi, Manny M. Semonis, Hideki Aihara, William C. K. Pomerantz +2 more

Metal binding 6-arylthio-3-hydroxypyrimidine-2,4-diones inhibited human cytomegalovirus by targeting the pUL89 endonuclease of the terminase complex

European Journal of Medicinal Chemistry(2021)10.1016/j.ejmech.2021.113640

N/A

0DataRank · unranked

7 citations

Tiffany C. Edwards, Rajkumar Lalji Sahani, Jiashu Xie, Hideki Aihara, Robert J. Geraghty +2 more

Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.02.438274

N/A

0DataRank · unranked

24 citations

Ke Shi, Özlem Demir, Surajit Banerjee, Lulu Yin, Christopher Belica +4 more