Thomas J. Abbruscato

Also affiliated with Texas Tech University Health Sciences Center

NeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19”.

The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19

Journal of Pharmacology and Experimental Therapeutics(2020)10.1124/jpet.120.000170

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42 citations

Saeideh Nozohouri, Heidi Villalba, Bhuvaneshwar Vaidya, Thomas J. Abbruscato, Ali Ehsan Sifat

Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke

Life Sciences(2021)10.1016/j.lfs.2021.119343

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57 citations

Saeideh Nozohouri, Bhuvaneshwar Vaidya, Thomas J. Abbruscato, Sejal Sharma

Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers

Fluids and Barriers of the CNS(2021)10.1186/s12987-021-00261-4

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35 citations

Behnam Noorani, Ulrich Bickel, Thomas J. Abbruscato, Luca Cucullo, Hossam Kadry

Brain Energy Metabolism in Ischemic Stroke: Effects of Smoking and Diabetes

International Journal of Molecular Sciences(2022)10.3390/ijms23158512

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65 citations

Saeideh Nozohouri, Sabrina Rahman Archie, Ekram Ahmed Chowdhury, Thomas J. Abbruscato, Ali Ehsan Sifat

Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping

Fluids and Barriers of the CNS(2022)10.1186/s12987-022-00339-7

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31 citations

Sabrina Rahman Archie, Yashwardhan Ghanwatkar, Sejal Sharma, Saeideh Nozohouri, Elizabeth Burks +4 more

Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome

Fluids and Barriers of the CNS(2022)10.1186/s12987-022-00371-7

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26 citations

Sabrina Rahman Archie, Saeideh Nozohouri, Heidi Villalba, Yong Zhang, Sejal Sharma +6 more

Effects of Nicotine Exposure From Tobacco Products and Electronic Cigarettes on the Pathogenesis of Neurological Diseases: Impact on CNS Drug Delivery

Frontiers in Drug Delivery(2022)10.3389/fddev.2022.886099

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19 citations

Sabrina Rahman Archie, Vrajesh Kanchanwala, Kyle Mimun, Md. Ashrafur Rahman, Yong Zhang +2 more

In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals

Pharmaceutical Research(2022)10.1007/s11095-022-03218-w

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12 citations

Shiva Hadi Esfahani, Behnam Noorani, Dhaval Patel, Heidi Villalba, Yashwardhan Ghanwatkar +7 more

Structure-activity relationship studies of functionalized aromatic peptidomimetics as neurolysin activators

Bioorganic & Medicinal Chemistry Letters(2022)10.1016/j.bmcl.2022.128669

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7 citations

Shiva Hadi Esfahani, Saeideh Nozohouri, Shikha Kumari, Joanna Kocot, Yong Zhang +4 more

Prenatal E‐Cigarette Use Disrupts Blood‐Brain Barrier (BBB) Integrity and Induces Pro‐Inflammatory Cytokines in Postnatal Brain

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2831

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0 citations

Ali Ehsan Sifat, Heidi Villalba, Sejal Sharma, Saeideh Nozohouri, Yong Zhang +2 more

Short-term Exposure to JUUL Electronic Cigarettes Can Worsen Ischemic Stroke Outcome by Disrupting the Blood-Brain Barrier

Research Square(2022)10.21203/rs.3.rs-1581624/v1

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0 citations

Sabrina Rahman Archie, Saeideh Nozohouri, Heidi Villalba, Yashwardhan Ghanwatkar, Sejal Sharma +5 more

Maternal E-Cigarette Use Can Disrupt Postnatal Blood-Brain Barrier (BBB) Integrity and Deteriorates Motor, Learning and Memory Function: Influence of Sex and Age

Research Square(2022)10.21203/rs.3.rs-2348460/v1

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0 citations

Ali Ehsan Sifat, Yong Zhang, Heidi Villalba, Sejal Sharma, Saeideh Nozohouri +2 more

Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)

Pharmaceutics(2023)10.3390/pharmaceutics15051357

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48 citations

Yong Zhang, Khondker Ayesha Akter, Saeideh Nozohouri, Sabrina Rahman Archie, Dhaval Patel +3 more

Maternal e-cigarette use can disrupt postnatal blood-brain barrier (BBB) integrity and deteriorates motor, learning and memory function: influence of sex and age

Fluids and Barriers of the CNS(2023)10.1186/s12987-023-00416-5

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35 citations

Ali Ehsan Sifat, Yong Zhang, Heidi Villalba, Sejal Sharma, Saeideh Nozohouri +2 more

Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function

Frontiers in Pharmacology(2023)10.3389/fphar.2023.1227145

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14 citations

Ali Ehsan Sifat, D. Duncan Mara, Yeseul Ahn, Khondker Ayesha Akter, Yong Zhang +3 more

Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals

Pharmaceutical Research(2023)10.1007/s11095-023-03619-5

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6 citations

Sejal Sharma, Shirisha Jonnalagadda, Shikha Kumari, Aarfa Queen, Shiva Hadi Esfahani +7 more

Endothelial-Specific Targeting of RhoA Signaling via CD31 Antibody-Conjugated Nanoparticles

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.001384

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11 citations

Racheal G. Akwii, Dhavalkumar Patel, Siavash ShahbaziNia, Μαργαρίτα Λάμπρου, Mahboubeh Madadi +8 more

Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115309

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10 citations

Mohammad Anwar Hossain, Guangchen Ji, Sravan K. Jonnalagadda, Samuel Obeng, Md. Ashrafur Rahman +14 more

High brain-blood barrier permeability highlights a new class of neurolysin activators as promising candidates for stroke treatment: a pilot pharmacokinetic study in mice

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.533120

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0 citations

Sejal Sharma, Shiva Hadi Esfahani, Shirisha Jonnalagadda, Aarfa Queen, Saeideh Nozohouri +5 more

Metformin ameliorates neuroinflammatory environment for neurons and astrocytes during in vitro and in vivo stroke and tobacco smoke chemical exposure: Role of Nrf2 activation

Redox Biology(2024)10.1016/j.redox.2024.103266

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32 citations

Sejal Sharma, Ali Ehsan Sifat, Yong Zhang, Dhaval Patel, Luca Cucullo +2 more

Evaluation of systemic and brain pharmacokinetic parameters for repurposing metformin using intravenous bolus administration

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.124.002152

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10 citations

Yong Zhang, Dhavalkumar Patel, Khondker Ayesha Akter, Sounak Bagchi, Ali Ehsan Sifat +5 more

Brain endothelial permeability, transport, and flow assessed over 10 orders of magnitude using the in situ brain perfusion technique

Fluids and Barriers of the CNS(2024)10.1186/s12987-024-00584-y

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2 citations

Haritha Mandula, Jagan Mohan R. Parepally, Jun Oki, Fancy Thomas, Helen R. Thorsheim +6 more

Metformin’s protection against blood-brain barrier disruption and neuronal dysfunction under oxygen-glucose deprivation and tobacco smoke and e-vape chemical exposure

Fluids and Barriers of the CNS(2025)10.1186/s12987-025-00719-9

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3 citations

Sejal Sharma, Sejal Rajesh Jadhav, Yong Zhang, Thomas J. Abbruscato, Khondker Ayesha Akter