🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Alvaro Sebastian Vaca Jácome

Broad Institute

ORCID: 0000-0001-7664-4660

Also affiliated with Bruker (United States), BioNTech (United States), Bruker (Canada)

ChemistryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile
0.697Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds

Scientific Data(2021)10.1038/s41597-021-01008-4
Top 33%
0.593DataRank
Top 33%17 citations

Karen E. Christianson, Shawn B. Egri, Alvaro Sebastian Vaca Jácome, Katherine C. DeRuff, James Mullahoo +19 more

Papers

Driven by 11 papers — median percentile 44. Top paper: “Causal interactions from proteomic profiles: Molecular data meet pathway knowledge”.

Causal interactions from proteomic profiles: Molecular data meet pathway knowledge

Patterns(2021)10.1016/j.patter.2021.100257
N/A
0.677DataRank · unranked
90 citations

Augustin Luna, Anil Korkut, Funda Durupınar, Metin Can Siper, Uğur Doğrusöz +9 more

Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds

Scientific Data(2021)10.1038/s41597-021-01008-4
Top 33%
0.593DataRank
Top 33%17 citations

Karen E. Christianson, Shawn B. Egri, Alvaro Sebastian Vaca Jácome, Katherine C. DeRuff, James Mullahoo +19 more

Cloud-based DIA data analysis module for signal refinement improves accuracy and throughput of large datasets

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.14.452243
N/A
0.104DataRank · unranked
1 citations

Jacob D. Jaffe, Steven A. Carr, Alvaro Sebastian Vaca Jácome, Karen E. Christianson

Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100947
Top 78%
0.104DataRank
Top 78%1 citations

Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril +69 more

Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors

Journal of Clinical Investigation(2024)10.1172/jci180347
N/A
0DataRank · unranked
16 citations

Matthew Brown, Jason Zavras, Magdalena Riedl Khursigara, Elizabeth Grinkevich, Eriene-Heidi Sidhom +29 more

Mass spectrometry-based profiling of single-cell histone post-translational modifications to dissect chromatin heterogeneity

Nature Communications(2025)10.1038/s41467-025-66031-0
N/A
0DataRank · unranked
3 citations

Laura Corveleyn, Claudia Ctortecka, Francesca LiCausi, Joshua Cantlon, Alvaro Sebastian Vaca Jácome +7 more

High-Throughput Determination of Exchange Rates of Unmodified and PTM-Containing Peptides Using HX-MS

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100904
N/A
0DataRank · unranked
5 citations

Alvaro Sebastian Vaca Jácome, Pierre Michel Jean Beltran, Andrew H. Reiter, Charles C. Mundorff, Miklos Guttman +7 more

Corrigendum to “Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data”

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100995
N/A
0DataRank · unranked
0 citations

Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril +68 more

Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks

Molecular Cell(2022)10.1016/j.molcel.2022.09.012
N/A
0DataRank · unranked
48 citations

Lahiri Konada, Lance Heady, Richard Rueda, Alvaro Sebastian Vaca Jácome, Eric Marlin +8 more

Sensitive, High-Throughput HLA-I and HLA-II Immunopeptidomics Using Parallel Accumulation-Serial Fragmentation Mass Spectrometry

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100563
N/A
0DataRank · unranked
50 citations

Claudia Ctortecka, Alvaro Sebastian Vaca Jácome, Susan Klaeger, Eva K. Verzani, Gabrielle M. Hernandez +5 more

Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.10.532106
N/A
0DataRank · unranked
6 citations

Claudia Ctortecka, Alvaro Sebastian Vaca Jácome, Susan Klaeger, Eva K. Verzani, Gabrielle M. Hernandez +5 more