Pamela J. Lein

Agricultural and Biological SciencesNeuroscienceEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 64 papers. Top paper: “A non-hallucinogenic psychedelic analogue with therapeutic potential”.

A non-hallucinogenic psychedelic analogue with therapeutic potential

Nature(2020)10.1038/s41586-020-3008-z

N/A

9.0DataRank · unranked

468 citations

Robert J. Tombari, Ju Lu, Alexander J. Pell, Zefan Q. Hurley, Yann Ehinger +24 more

Developmental exposure to DDT or DDE alters sympathetic innervation of brown adipose in adult female mice

Environmental Health(2021)10.1186/s12940-021-00721-2

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0.848DataRank · unranked

24 citations

Sarah E. Elmore, Kyle B Jackson, Beth A. Habecker, Katherine E. Manz, Kurt D. Pennell +3 more

A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation

Journal of Neuroinflammation(2020)10.1186/s12974-020-01819-z

N/A

0.829DataRank · unranked

251 citations

Rhianna K. Morgan, Pamela J. Lein, Erkin Şeker, Noah Goshi

Mechanisms of organophosphate neurotoxicity

Current Opinion in Toxicology(2021)10.1016/j.cotox.2021.04.002

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0.740DataRank · unranked

138 citations

Pamela J. Lein, Yi-Hua Tsai

Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats

Current Research in Toxicology(2021)10.1016/j.crtox.2021.09.002

N/A

0.699DataRank · unranked

18 citations

Jonas J. Calsbeek, Yi-Hua Tsai, Mei-Yun Tang, Peter M. Andrew, Joan Vu +8 more

A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent

Critical Reviews in Toxicology(2020)10.1080/10408444.2020.1787330

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0.568DataRank · unranked

43 citations

Christopher A. Sibrizzi, Robyn Blain, Pamela Hartman, Pamela J. Lein, Kyla W. Taylor +2 more

Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment

Environmental Research(2023)10.1016/j.envres.2023.115227

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0.489DataRank · unranked

25 citations

Xueshu Li, Kari Neier, Yihui Zhu, Charles E. Mordaunt, Michele A. La Merrill +6 more

Hippocampal but Not Serum Cytokine Levels Are Altered by Traffic-Related Air Pollution in TgF344-AD and Wildtype Fischer 344 Rats in a Sex- and Age-Dependent Manner

Frontiers in Cellular Neuroscience(2022)10.3389/fncel.2022.861733

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0.434DataRank · unranked

17 citations

Anthony E. Valenzuela, Christopher Wallis, Danielle Harvey, Keith J. Bein, Anthony S. Wexler +3 more

In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder

Current Research in Toxicology(2021)10.1016/j.crtox.2021.01.002

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0.416DataRank · unranked

15 citations

C. Kennedy, Sunjay Sethi, Anthony E. Valenzuela, Alexandra Nunez, Kathy Wang +7 more

Probing changes in brain esterified oxylipin concentrations during the early stages of pathogenesis in Alzheimer’s Disease transgenic rats

Neuroscience Letters(2022)10.1016/j.neulet.2022.136921

N/A

0.416DataRank · unranked

15 citations

Kelley T. Patten, Anthony E. Valenzuela, Pamela J. Lein, Ameer Y. Taha, Qing Shen

Identification of polychlorinated biphenyls (PCBs) and PCB metabolites associated with changes in the gut microbiome of female mice exposed to an environmental PCB mixture

Journal of Hazardous Materials(2025)10.1016/j.jhazmat.2025.137688

N/A

0.396DataRank · unranked

13 citations

Hui Wang, Xueshu Li, Rachel L. Fitzjerrells, Anthony E. Valenzuela, Kari Neier +5 more

Automated high content image analysis of dendritic arborization in primary mouse hippocampal and rat cortical neurons in culture

Journal of Neuroscience Methods(2020)10.1016/j.jneumeth.2020.108793

N/A

0.385DataRank · unranked

12 citations

Kimberly P. Keil, Sunjay Sethi, Rhianna K. Morgan, Pamela J. Lein, Martin Schmuck

A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures

Neuropharmacology(2024)10.1016/j.neuropharm.2024.109918

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0.269DataRank · unranked

5 citations

Douglas J. Rowland, Yimeng Dou, Naomi Saito, Zachary T. Harmany, Donald A. Bruun +5 more

Genome-Wide DNA Methylation Profiles of Neurodevelopmental Disorder Genes in Mouse Placenta and Fetal Brain Following Prenatal Exposure to Polychlorinated Biphenyls

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.27.446011

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0.269DataRank · unranked

5 citations

Kari Neier, Anthony E. Valenzuela, Dag H. Yasui, Rebecca J. Schmidt, Pamela J. Lein +2 more

Glioma-associated microglia/macrophages augment tumorigenicity in canine astrocytoma, a naturally occurring model of human glioma

Neuro-Oncology Advances(2021)10.1093/noajnl/vdab062

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0DataRank · unranked

16 citations

Ana Cristina Grodzki, Peter J. Dickinson, Kevin Woolard, Nicole Vinson, Beverly K. Sturges +10 more

Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus

NeuroToxicology(2021)10.1016/j.neuro.2021.08.011

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0DataRank · unranked

4 citations

Eduardo González, Casey A. Boosalis, Dorota Żółkowska, Donald A. Bruun, Douglas J. Rowland +7 more

Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

Progress in Lipid Research(2022)10.1016/j.plipres.2022.101165

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0DataRank · unranked

624 citations

Laurence Balas, Nicolás G. Bazán, J. Thomas Brenna, Nan Chiang, Felipe da Costa Souza +7 more

Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure

Cell Reports(2022)10.1016/j.celrep.2022.110442

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0DataRank · unranked

84 citations

Kari Neier, Anthony E. Valenzuela, Dag H. Yasui, Rebecca J. Schmidt, Pamela J. Lein +2 more

Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer’s disease

Toxicology Reports(2022)10.1016/j.toxrep.2022.03.003

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0DataRank · unranked

19 citations

Kris M. Weigel, Kelley T. Patten, Anthony E. Valenzuela, Christopher Wallis, Keith J. Bein +4 more

Influence of microchannel geometry on device performance and electrophysiological recording fidelity during long-term studies of connected neural populations

Lab on a Chip(2022)10.1039/d2lc00683a

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0DataRank · unranked

19 citations

Gregory Girardi, Felipe da Costa Souza, Alexander Gardner, Pamela J. Lein, Erkin Şeker +1 more

Chronic exposure to traffic-related air pollution reduces lipid mediators of linoleic acid and soluble epoxide hydrolase in serum of female rats

Environmental Toxicology and Pharmacology(2022)10.1016/j.etap.2022.103875

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0DataRank · unranked

11 citations

Shiva Emami, Kelley T. Patten, Anthony E. Valenzuela, Christopher Wallis, Anthony S. Wexler +4 more

Pro-resolving Lipid Mediators Within Brain Esterified Lipid Pools are Reduced in Female Rats Chronically Exposed to Traffic-Related Air Pollution or Genetically Susceptible to Alzheimer’s Disease Phenotype

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.16.480656

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0DataRank · unranked

3 citations

Nuanyi Liang, Kelley T. Patten, Yurika Otoki, Anthony E. Valenzuela, Christopher Wallis +5 more

Effects of Senescent Human Endothelial Cells on Neuronal Viability and Neurite Outgrowth Are Not IL‐8‐ or Serpin E1‐Dependent

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5199

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0DataRank · unranked

0 citations

Yun Lin, Anne A. Knowlton, Pamela J. Lein, Ana C. Grodzki

Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment

medRxiv(2022)10.1101/2022.11.13.22282272

N/A

0DataRank · unranked

0 citations

Xueshu Li, Kari Neier, Yihui Zhu, Charles E. Mordaunt, Michele A. La Merrill +6 more

Oxidized linoleic acid metabolites regulate neuronal morphogenesis in vitro

Neurochemistry International(2023)10.1016/j.neuint.2023.105506

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0DataRank · unranked

24 citations

Ana Cristina Grodzki, Rhianna K. Morgan, Zhichao Zhang, Ameer Y. Taha, Pamela J. Lein +1 more

Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish (Danio rerio)

ACS Chemical Neuroscience(2023)10.1021/acschemneuro.2c00642

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0DataRank · unranked

15 citations

Paige C. Mundy, Kelly M. Morales, Lee E. Dunlap, David E. Olson, Pamela J. Lein +1 more

Rebuttal to Correspondence on “Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples”

Environmental Science & Technology(2023)10.1021/acs.est.3c01659

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0DataRank · unranked

1 citations

Xueshu Li, Kimberly P. Keil, Sunjay Sethi, Weizhu Yang, Rachel F. Marek +5 more

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2 responding CD4 + T cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.25.559429

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0DataRank · unranked

0 citations

Keegan Malany, Krista Thongphanh, Clarisa Martinez, Michael L. Goodson, Felipe da Costa Souza +6 more

Interactions of Polychlorinated Biphenyls and Their Metabolites with the Brain and Liver Transcriptome of Female Mice

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00367

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0DataRank · unranked

20 citations

Hui Wang, Anthony E. Valenzuela, Kari Neier, Rebecca J. Wilson, Jessie R Badley +5 more

Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate

Journal of Neuroinflammation(2024)10.1186/s12974-024-03272-8

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0DataRank · unranked

10 citations

Jeremy A. MacMahon, Pedro N. Bernardino, Yi‐Hua Tsai, Brad A. Hobson, Valerie A. Porter +9 more

Dietary resistant starch supplementation increases gut luminal deoxycholic acid abundance in mice

Gut Microbes(2024)10.1080/19490976.2024.2315632

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0DataRank · unranked

21 citations

Madelynn Tucker, Zara Marfori, Rahaf Shishani, Jessica Miranda Bustamante, Rosalinda Moreno +10 more

Fully automated whole brain segmentation from rat MRI scans with a convolutional neural network

Journal of Neuroscience Methods(2024)10.1016/j.jneumeth.2024.110078

N/A

0DataRank · unranked

10 citations

Brad A. Hobson, Brent Foster, Pamela J. Lein, Abhijit J. Chaudhari, Valerie A. Porter

The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats

Aging(2024)10.18632/aging.205741

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0DataRank · unranked

10 citations

Zabrisky Roland, Anthony E. Valenzuela, An B. Nguyen, Heui Hye Park, Natalie Six +5 more

Primary cortical cell tri-culture to study effects of amyloid-β on microglia function and neuroinflammatory response

Journal of Alzheimer s Disease(2024)10.1177/13872877241291142

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0DataRank · unranked

9 citations

Bryan Le, Noah Goshi, Kan Zhu, Ana Cristina Grodzki, Pamela J. Lein +3 more

Significant metabolic alterations in mouse dams exposed to an environmental mixture of polychlorinated biphenyls (PCBs) during gestation and lactation: Insights into PCB and metabolite profiles

Environmental Toxicology and Pharmacology(2024)10.1016/j.etap.2024.104567

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0DataRank · unranked

7 citations

Youjun Suh, Rebecca J. Wilson, Pamela J. Lein, Julia Yue Cui, Hans‐Joachim Lehmler +1 more

Intraperitoneally injected d11-11(12)-epoxyeicosatrienoic acid is rapidly incorporated and esterified within rat plasma and peripheral tissues but not the brain

Prostaglandins Leukotrienes and Essential Fatty Acids(2024)10.1016/j.plefa.2024.102622

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0DataRank · unranked

7 citations

Felipe da Costa Souza, Ibuki Kusumoto, Qing Shen, Nitin Nitin, Pamela J. Lein +2 more

Quantitative T2 mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication

Neuropharmacology(2024)10.1016/j.neuropharm.2024.109895

N/A

0DataRank · unranked

2 citations

Brad A. Hobson, Naomi Saito, Donald A. Bruun, Valerie A. Porter, Danielle Harvey +4 more

Cardiovascular responses of adult male Sprague–Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone

Archives of Toxicology(2024)10.1007/s00204-023-03679-x

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0DataRank · unranked

2 citations

Donald A. Bruun, Pamela J. Lein, Chao-Yin Chen, Shiyue Pan

The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability

Toxics(2024)10.3390/toxics12040263

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0DataRank · unranked

2 citations

Wayne Wei Feng, Jonas J. Calsbeek, Shane Antrobus, Gennady A. Cherednychenko, Jeremy A. MacMahon +6 more

Rat primary cortical cell tri-culture to study effects of amyloid-beta on microglia function

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.15.584736

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0DataRank · unranked

0 citations

Bryan Le, Noah Goshi, Kan Zhu, Ana Cristina Grodzki, Pamela J. Lein +3 more

Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication

Acta Neuropathologica Communications(2025)10.1186/s40478-025-01979-0

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0DataRank · unranked

5 citations

Jeremy A. MacMahon, Pedro N. Bernardino, Ryan E. Hogans, Mei-Yun Cheng, Joan Vu +11 more

Bile Acid Profile Differs Between Brain Regions in Rodents and Is Disrupted in a Rodent Model of Alzheimer's Disease

Comprehensive physiology(2025)10.1002/cph4.70034

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0DataRank · unranked

3 citations

Rosalinda Moreno, Madelynn E. Agabao‐Tucker, Rahaf Shishani, Jessica Miranda Bustamante, Zara Marfori +7 more

A primary rat neuron-astrocyte-microglia tri-culture model for studying mechanisms of neurotoxicity

Frontiers in Toxicology(2025)10.3389/ftox.2024.1523387

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0DataRank · unranked

2 citations

Aishwarya Bhusal, Pamela J. Lein, Jessie R Badley

Three-dimensional U-Net with transfer learning improves automated whole brain delineation from MRI brain scans of rats, mice, and monkeys

Computers in Biology and Medicine(2025)10.1016/j.compbiomed.2025.110569

N/A

0DataRank · unranked

2 citations

Brad A. Hobson, Alita J D'Almeida, Karen L. Bales, Pamela J. Lein, Abhijit J. Chaudhari +1 more

Air pollution and Alzheimer disease phenotype deplete esterified proresolving lipid mediator reserves in the brain

JCI Insight(2025)10.1172/jci.insight.175917

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0DataRank · unranked

1 citations

Qing Shen, Yurika Otoki, Nuanyi Liang, Kelley T. Patten, Anthony E. Valenzuela +10 more

PCB 37 (3,4, 4’-trichlorobiphenyl) increased apoptosis and modulated neuronal morphogenesis in primary rat cortical neuron-glia cocultures in a concentration-, sex-, age-, and CREB-dependent manner

NeuroToxicology(2025)10.1016/j.neuro.2025.08.004

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0DataRank · unranked

1 citations

Peter M. Andrew, Hans‐Joachim Lehmler, Pamela J. Lein, Jessie R Badley

Single-cell transcriptomics showed that maternal PCB exposure dysregulated ER stress-mediated cell type-specific responses in the liver of female offspring

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.04.657944

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0DataRank · unranked

0 citations

Youjun Suh, Xueshu Li, Rebecca J. Wilson, Hans‐Joachim Lehmler, Pamela J. Lein +2 more

Spatial and spectral mapping of traffic-related air pollution (TRAP) nanoparticles in relation to plaques and inflammatory markers in an Alzheimer disease model

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.01.662638

N/A

0DataRank · unranked

0 citations

A. Everette James, Nasir Nasim, Dustin J. Hadley, Enatra Hale, Qing He +8 more

Dantrolene normalizes heightened Ca2+ influx in activated T cells from the familial Alzheimer's disease TgF344-AD rats

Cell Calcium(2025)10.1016/j.ceca.2025.103072

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0DataRank · unranked

0 citations

Anthony E. Valenzuela, Pamela J. Lein, Alla F. Fomina, Navdeep K. Uppal

Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100174

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0DataRank · unranked

0 citations

Youjun Suh, Xueshu Li, R. Wilson, Hans‐Joachim Lehmler, Pamela J. Lein +2 more

Dataset for 3,3'-Dichlorobiphenyl (PCB 11) Alters the Hepatic Expression of Cytochrome P450 Enzymes in the Liver of Mouse Dams Exposed Orally During Pregnancy and Lactation.

Iowa Research Online (The University of Iowa)(2025)10.25820/data.007803

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0DataRank · unranked

0 citations

Roach, Crystal M, Koester, Nate R., Ahn, Jeonghyeon, Pope, R Marshall, Wilson, Rebecca J. +7 more

Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth

ACS Pharmacology & Translational Science(2020)10.1021/acsptsci.0c00065

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0DataRank · unranked

127 citations

Alexandra C. Greb, Maxemiliano V. Vargas, Whitney C. Duim, Ana Cristina Grodzki, Pamela J. Lein +2 more

Translational toxicology in zebrafish

Current Opinion in Toxicology(2020)10.1016/j.cotox.2020.05.004

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0DataRank · unranked

72 citations

Bianca Yaghoobi, Pamela J. Lein, Tamara Tal

Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats

Translational Psychiatry(2020)10.1038/s41398-020-0845-3

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0DataRank · unranked

57 citations

Eduardo A. González, Anthony E. Valenzuela, Elizabeth L. Berg, Christopher Wallis, Joel R. Garbow +5 more

Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation

Scientific Reports(2020)10.1038/s41598-020-65090-1

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0DataRank · unranked

13 citations

Michael C. Pride, Carolyn Klocke, Timothy A. Fenton, Jeannine Logan White, Pamela J. Lein +5 more

Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate

European Journal of Pharmacology(2020)10.1016/j.ejphar.2020.173538

N/A

0DataRank · unranked

32 citations

Eduardo A. González, Douglas J. Rowland, Brad A. Hobson, Donald A. Bruun, Michelle Guignet +7 more

Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats

Translational Psychiatry(2020)10.1038/s41398-020-00978-0

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0DataRank · unranked

30 citations

Lauren R. Pedersen, Michael C. Pride, Stela P. Petkova, Kelley T. Patten, Anthony E. Valenzuela +6 more

Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform

Frontiers in Cell and Developmental Biology(2020)10.3389/fcell.2020.586296

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0DataRank · unranked

27 citations

José M. Uribe‐Salazar, KaeChandra B. Weyenberg, Aditya Sriram, Alejandra Quezada, Gulhan Kaya +5 more

Magnitude of behavioral deficits varies with job-related chlorpyrifos exposure levels among Egyptian pesticide workers

NeuroToxicology(2020)10.1016/j.neuro.2020.01.012

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0DataRank · unranked

24 citations

Fayssal Farahat, Pamela J. Lein, Michael Lasarev, James R. Olson, Taghreed Farahat +2 more

A Primary Neural Cell Culture Model for Neuroinflammation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.23.914226

N/A

0DataRank · unranked

2 citations

Rhianna K. Morgan, Pamela J. Lein, Erkin Şeker, Noah Goshi

Assessment of autism zebrafish mutant models using a high-throughput larval phenotyping platform

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.23.217273

N/A

0DataRank · unranked

0 citations

José M. Uribe‐Salazar, KaeChandra Weyenberg, Aditya Sriram, Alejandra Quezada, Gulhan Kaya +5 more

The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer’s Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats

Environmental Health Perspectives(2021)10.1289/ehp8905

N/A

0DataRank · unranked

91 citations

Anthony E. Valenzuela, Christopher Wallis, Elizabeth L. Berg, Jill L. Silverman, Keith J. Bein +3 more

Neuroinflammation as a Therapeutic Target for Mitigating the Long-Term Consequences of Acute Organophosphate Intoxication

Frontiers in Pharmacology(2021)10.3389/fphar.2021.674325

N/A

0DataRank · unranked

34 citations

Pamela J. Lein, Peter M. Andrew

Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate

NeuroToxicology(2021)10.1016/j.neuro.2021.09.001

N/A

0DataRank · unranked

14 citations

Eduardo A. González, Donald A. Bruun, Michelle Guignet, Nycole A. Copping, Mallory E. Dawson +7 more