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Jonathan L. Chen

Jonathan L. Chen

Scripps Research Institute

ORCID: 0000-0001-7907-9732

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 15 papers. Top paper: “Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau’s Pre-mRNA Splicing”.

Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau’s Pre-mRNA Splicing

ACS Chemical Biology(2025)10.1021/acschembio.5c00260

N/A

0.104DataRank · unranked

1 citations

Amirhossein Taghavi, Masahito Abe, Haruo Aikawa, Yoshihiro Akahori, Jonathan L. Chen +6 more

A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex

Cell chemical biology(2020)10.1016/j.chembiol.2020.10.007

N/A

0DataRank · unranked

48 citations

Raphael I. Benhamou, Suzanne G. Rzuczek, Shruti Choudhary, Zhenzhi Tang, Jonathan L. Chen +7 more

Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD

ACS Chemical Biology(2020)10.1021/acschembio.0c00049

N/A

0DataRank · unranked

20 citations

Kye Won Wang, Jessica A. Bush, Shruti Choudhary, Jonathan L. Chen, Jared T. Baisden +6 more

A small molecule that binds an RNA repeat expansion stimulates its decay via the exosome complex

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.11.088427

N/A

0DataRank · unranked

3 citations

Raphael I. Benhamou, Suzanne G. Rzuczek, Shruti Choudhary, Zhenzhi Tang, Jonathan L. Chen +7 more

Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G 4 C 2 ) repeat expansion in vitro and in vivo ALS models

Science Translational Medicine(2021)10.1126/scitranslmed.abd5991

N/A

0DataRank · unranked

80 citations

Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M. Meyer +19 more

A Druglike Small Molecule that Targets r(CCUG) Repeats in Myotonic Dystrophy Type 2 Facilitates Degradation by RNA Quality Control Pathways

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00414

N/A

0DataRank · unranked

17 citations

Masahito Abe, Raphael I. Benhamou, Alicia J. Angelbello, Kamalakannan Vishnu, Jonathan L. Chen +3 more

Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes

Molecular Cell(2023)10.1016/j.molcel.2023.01.009

N/A

0DataRank · unranked

69 citations

Yi Pan, Xueyang He, Jonathan L. Chen, Bart Klein, Gerard Platenburg +4 more

Broad-spectrum metastasis suppressing compounds and therapeutic uses thereof in human tumors

Scientific Reports(2023)10.1038/s41598-023-47478-x

N/A

0DataRank · unranked

3 citations

Jonathan L. Chen, Jessica L. Childs‐Disney, Matthew D. Disney, Dan Canaani, Pnina Gottfried Komlosh

NMR structures of small molecules bound to a model of a CUG RNA repeat expansion

Bioorganic & Medicinal Chemistry Letters(2024)10.1016/j.bmcl.2024.129888

N/A

0DataRank · unranked

6 citations

Amirhossein Taghavi, Alexander J. Frank, Matthew A. Fountain, Shruti Choudhary, Soma Roy +3 more

Updated Pseudo-seq Protocol for Transcriptome-Wide Detection of Pseudouridines

BIO-PROTOCOL(2024)10.21769/bioprotoc.4985

N/A

0DataRank · unranked

1 citations

Hironori Adachi, Xueyang He, Jonathan L. Chen, Yi‐Tao Yu, Paul L. Boutz +1 more

NMR structures of small molecules bound to a model of an RNA CUG repeat expansion

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.21.600119

N/A

0DataRank · unranked

2 citations

Amirhossein Taghavi, Alexander J. Frank, Matthew A. Fountain, Shruti Choudhary, Soma Roy +3 more

RNA‐Guided RNA Pseudouridylation and 2’‐O‐Methylation

Israel Journal of Chemistry(2024)10.1002/ijch.202400005

N/A

0DataRank · unranked

0 citations

Jonathan L. Chen, W.‐Matthias Leeder, Pedro Morais, Yi‐Tao Yu, Hironori Adachi

NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansion

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.20.608150

N/A

0DataRank · unranked

0 citations

Jonathan L. Chen, Zhen Wang, Krishshanthi Sinnadurai, David Georges Salthouse, Matthew Ozon +6 more

Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing

Journal of the American Chemical Society(2020)10.1021/jacs.0c00768

N/A

0DataRank · unranked

81 citations

Peiyuan Zhang, Masahito Abe, Haruo Aikawa, Liying Zhang, Alexander J. Frank +14 more

Design of an orally bioavailable small molecule that modulates the microtubule-associated protein tau’s pre-mRNA splicing

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.30.651234

N/A

0DataRank · unranked

0 citations

Amirhossein Taghavi, Masahito Abe, Haruo Aikawa, Yoshihiro Akahori, Jonathan L. Chen +6 more