Stephen J. Elledge

Also affiliated with Howard Hughes Medical Institute, Harvard University, Critical Path Institute, Center for Human Genetics

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 42 papers. Top paper: “Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity”.

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

Science(2020)10.1126/science.abd4250

N/A

14.5DataRank · unranked

769 citations

Eric Fujimura, Tomasz Kula, Richard T. Timms, I‐Hsiu Lee, Yumei Leng +95 more

High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100410

N/A

1.8DataRank · unranked

63 citations

Ellen Shrock, Mamie Z. Li, Jonathan M. Spergel, Kari C. Nadeau, Jacqueline A. Pongracic +8 more

Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer

Cancer Research(2024)10.1158/0008-5472.can-24-0970

N/A

0.774DataRank · unranked

28 citations

Timothy D. Martin, Haley E. Manchester, Jenny Högström, Na Zhang, Emmalyn Lecky +14 more

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Science(2023)10.1126/science.adh5021

N/A

0.755DataRank · unranked

152 citations

Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg +1 more

Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior

Genes & Development(2021)10.1101/gad.349048.121

N/A

0.724DataRank · unranked

24 citations

Bruno Di Stefano, Jessica Makofske, Emma V. Watson, Marit AC de Kort, Timothy D. Martin +7 more

TScan-II: A genome-scale platform for the de novo identification of CD4+ T cell epitopes

Cell(2023)10.1016/j.cell.2023.10.024

N/A

0.598DataRank · unranked

53 citations

Tomasz Kula, Thomas Pranzatelli, Nolan Kamitaki, Qingda Meng, Bhuwan Khatri +14 more

High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits

Nature Biotechnology(2024)10.1038/s41587-024-02248-6

N/A

0.571DataRank · unranked

44 citations

M Dezfulian, Brandon Sie, Charlotte I. Wang, Tomasz Kula, Uri Laserson +3 more

Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

Neuron(2024)10.1016/j.neuron.2024.06.002

N/A

0.520DataRank · unranked

31 citations

Alain Ndayisaba, Amanda J. Lewis, YuHong Fu, Giselle T. Sagredo, Anastasia Kuzkina +49 more

Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

iScience(2022)10.1016/j.isci.2022.104925

N/A

0.510DataRank · unranked

29 citations

Patrick T. Keiser, Deisy Morselli-Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J. Donahue +21 more

Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2

Nature Communications(2024)10.1038/s41467-024-52966-3

N/A

0.494DataRank · unranked

26 citations

Suresh Dharuman, Elizabeth C. Griffith, Sergio C. Chai, Jarrid Ronnebaum, Moeko T. King +17 more

A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells

Nature Communications(2022)10.1038/s41467-021-27731-5

N/A

0.483DataRank · unranked

24 citations

Rodrigo Romero, Emma V. Watson, Anthony C. Liang, Megan L. Burger, Peter M.K. Westcott +7 more

Signatures of AAV-2 immunity are enriched in children with severe acute hepatitis of unknown etiology

Science Translational Medicine(2023)10.1126/scitranslmed.adh9917

N/A

0.360DataRank · unranked

10 citations

Yumei Leng, Suresh B. Boppana, William J. Britt, Luz Helena Gutierrez Sanchez, Stephen J. Elledge +1 more

Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.20.440626

N/A

0.345DataRank · unranked

9 citations

Patrick T. Keiser, Deisy Morselli Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J. Donahue +21 more

Regulation and Function of Cellular Gene Products Involved in UV and Chemical Mutagenesis in E. Coli

Induced Mutagenesis(1983)10.1007/978-1-4684-4382-0_7

N/A

0.330DataRank · unranked

8 citations

Stephen J. Elledge, Karen L. Perry, Anne Bagg, Cynthia J. Kenyon, Graham C. Walker

Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation

Genes & Development(2025)10.1101/gad.352512.124

N/A

0.294DataRank · unranked

6 citations

Arshia N. Kaur, Faith Keller, Abdulrazak Frederick, Tenzin Tseyang, John D. Haley +7 more

An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity

Cell(2022)10.1016/j.cell.2022.01.009

N/A

0DataRank · unranked

124 citations

Valentina Poli, Ellen Shrock, Roberto Spreafico, Xin Liu, Novalia Pishesha +29 more

Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of α-synuclein inclusions

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.08.515615

N/A

0DataRank · unranked

9 citations

Alain Ndayisaba, Amanda J. Lewis, YuHong Fu, Giselle T. Sagredo, Ludovica Zaccagnini +44 more

The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair

Molecular Cell(2021)10.1016/j.molcel.2021.09.008

N/A

0DataRank · unranked

26 citations

Nicholas A. Willis, Andrew E. H. Elia, Connor S. Clairmont, Shibo Li, Xiaohua Wu +4 more

Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses

Science(2023)10.1126/science.adc9498

N/A

0DataRank · unranked

91 citations

Richard T. Timms, Tomasz Kula, Elijah L. Mena, Anthony P. West, Rui Guo +14 more

Defining E3 ligase–substrate relationships through multiplex CRISPR screening

Nature Cell Biology(2023)10.1038/s41556-023-01229-2

N/A

0DataRank · unranked

69 citations

Elijah L. Mena, Yumei Leng, Mamie Z. Li, Iva A. Tchasovnikarova, Itay Koren +2 more

ORF10–Cullin-2–ZYG11B complex is not required for SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2023157118

N/A

0DataRank · unranked

36 citations

Callie J. Donahue, Laura Pontano Vaites, Jie Li, Gergely Róna, Colin O’Leary +11 more

High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform

Nature Biotechnology(2023)10.1038/s41587-022-01566-x

N/A

0DataRank · unranked

50 citations

Richard T. Timms, Nouran S. Abdelfattah, Yumei Leng, Felipe Lelis, Duane R. Wesemann +3 more

A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

Molecular Cell(2023)10.1016/j.molcel.2022.12.013

N/A

0DataRank · unranked

50 citations

Brad A. Palanski, Daniel C. Scott, Richard T. Timms, Karl W. Barber, Xin Gu +7 more

Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping

Molecular Cell(2023)10.1016/j.molcel.2023.08.022

N/A

0DataRank · unranked

48 citations

Brandon Sie, Aiquan Chang, Yumei Leng, Christopher Nardone, Richard T. Timms +2 more

E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity

Molecular Cell(2023)10.1016/j.molcel.2023.01.019

N/A

0DataRank · unranked

38 citations

Moeko T. King, Kheewoong Baek, Clifford T. Gee, Ravi Kalathur, Jerry Li +10 more

Systematic characterization of mutations altering protein degradation in human cancers

Molecular Cell(2021)10.1016/j.molcel.2021.01.020

N/A

0DataRank · unranked

86 citations

Xiaoqing Wang, Richard T. Timms, Boning Zhang, Elijah L. Mena, Binbin Wang +8 more

Multiplex CRISPR screening to identify E3 ligase substrates

Research Square(2023)10.21203/rs.3.pex-2341/v1

N/A

0DataRank · unranked

1 citations

Elijah L. Mena, Stephen J. Elledge, Richard T. Timms

Data from CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells

(2023)10.1158/2159-8290.c.6549178.v1

N/A

0DataRank · unranked

0 citations

Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono +17 more

Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.30.551179

N/A

0DataRank · unranked

0 citations

Thiagarajan Venkataraman, William R. Morgenlander, Miso Na, Tomasz Kula, Kathleen Waugh +9 more

Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns

Nature Genetics(2024)10.1038/s41588-024-01665-2

N/A

0DataRank · unranked

56 citations

Jake June-Koo Lee, D. Gulhan, Giorgio Melloni, Sergey V. Venev, Rayna Y. Magesh +8 more

Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality

Journal of Clinical Investigation(2021)10.1172/jci146927

N/A

0DataRank · unranked

87 citations

Stephanie N. Henson, Daniel R. Monaco, Athena Chen, Kirsten Littlefield, Evan M. Bloch +24 more

CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1144

N/A

0DataRank · unranked

98 citations

Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono +17 more

Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction

Science(2021)10.1126/science.abc0476

N/A

0DataRank · unranked

156 citations

David L. Akey, Marcus P. Wong, William Clay Brown, Nicholas T. N. Lo, Henry Puerta‐Guardo +15 more

Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality

medRxiv(2020)10.1101/2020.12.16.20248294

N/A

0DataRank · unranked

17 citations

Stephanie N. Henson, Daniel R. Monaco, Athena Chen, Kirsten Littlefield, Evan M. Bloch +24 more

Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases

Nature Communications(2024)10.1038/s41467-024-54126-z

N/A

0DataRank · unranked

13 citations

Sagar Chittori, Nicholas Purser, Moeko T. King, Samuel Maiwald, Kelly Churion +9 more

The T cell receptor sequence influences the likelihood of T cell memory formation

Cell Reports(2024)10.1016/j.celrep.2024.115098

N/A

0DataRank · unranked

9 citations

Ayano C. Kohlgruber, Nouran S. Abdelfattah, Aparna Nathan, Laurie Rumker, Michael E. Birnbaum +3 more

Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn

Nature Communications(2024)10.1038/s41467-024-45601-8

N/A

0DataRank · unranked

9 citations

Thiagarajan Venkataraman, William R. Morgenlander, Miso Na, Tomasz Kula, Kathleen Waugh +9 more

T-Switch: A specificity-based engineering platform for developing safe and effective T cell therapeutics

Immunity(2024)10.1016/j.immuni.2024.11.009

N/A

0DataRank · unranked

9 citations

Tomasz Kula, Stephen J. Elledge, Nouran S. Abdelfattah

Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma

Molecular Cell(2025)10.1016/j.molcel.2025.05.030

N/A

0DataRank · unranked

16 citations

Jingjing Gao, Hyuk‐Soo Seo, Julian Mintseris, Lucy Ort, Matthew C. J. Yip +12 more

Conserved CD8 T cell vaccines without B cell epitopes drive robust protection against SARS-CoV-2 that is enhanced by intranasal boost

Science Advances(2025)10.1126/sciadv.adx0037

N/A

0DataRank · unranked

1 citations

Thao Nguyen, Lindsay G. A. McKay, Sravya Sowdamini Nakka, Pan Hu, Jana S. McBride +7 more

Genetic analysis of cancer drivers reveals cohesin and CTCF as suppressors of PD-L1

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2120540119

N/A

0DataRank · unranked

34 citations

Emily C. Wheeler, Kristen E. Mengwasser, Eric Fujimura, Timothy D. Martin, Zuzana Tóthová +2 more

High-Throughput Screening of Kawasaki Disease Sera for Antiviral Antibodies

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa253

N/A

0DataRank · unranked

15 citations

Tomasz Kula, Chisato Shimizu, John T. Kanegaye, Adriana H. Tremoulet, Zachary Pitkowsky +5 more