R. Graham Barr

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

10.5Author DataRank

Indexed papers

10in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 10 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Nature(2021)10.1038/s41586-021-03205-y

Top 3%

7.0DataRank

Top 3%2322 citations

Daniel Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raúl Torres +95 more

Papers

Driven by 129 papers — median percentile 48. Top paper: “Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection”.

Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection

JAMA(2023)10.1001/jama.2023.8823

N/A

10.9DataRank · unranked

865 citations

Sarah E. Jolley, Elizabeth W. Karlson, Emily B. Levitan, Bruce D. Levy, Grace A. McComsey +95 more

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers

American Journal of Respiratory and Critical Care Medicine(2020)10.1164/rccm.202006-2248oc

N/A

7.3DataRank · unranked

184 citations

Brett M. Elicker, Travis S. Henry, David S. Gierada, Mark L. Schiebler, Wayne H. Anderson +29 more

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Nature Genetics(2022)10.1038/s41588-021-00997-7

N/A

7.2DataRank · unranked

363 citations

Deepti Jain, Zhili Zheng, TOPMed Anthropometry Working Group, Stella Aslibekyan, Diane M. Becker +95 more

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Nature(2021)10.1038/s41586-021-03205-y

Top 3%

7.0DataRank

Top 3%2322 citations

Daniel Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raúl Torres +95 more

Genetic diversity fuels gene discovery for tobacco and alcohol use

Nature(2022)10.1038/s41586-022-05477-4

N/A

5.9DataRank · unranked

513 citations

Xingyan Wang, Fang Chen, Seon-Kyeong Jang, Mengzhen Liu, Chen Wang +95 more

Reconsidering the Utility of Race-Specific Lung Function Prediction Equations

American Journal of Respiratory and Critical Care Medicine(2021)10.1164/rccm.202105-1246oc

N/A

5.9DataRank · unranked

112 citations

Stephen Shiboski, Nadia N. Hansel, Victor E. Ortega, Igor Barjaktarević, R. Graham Barr +21 more

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

Nature Genetics(2020)10.1038/s41588-020-0676-4

N/A

5.3DataRank · unranked

295 citations

Zilin Li, Hufeng Zhou, Sheila M. Gaynor, Yaowu Liu, Han Chen +88 more

Clonal haematopoiesis and risk of chronic liver disease

Nature(2023)10.1038/s41586-023-05857-4

N/A

4.5DataRank · unranked

204 citations

Connor A. Emdin, Alexander G. Bick, Seyedeh M. Zekavat, Abhishek Niroula, James P. Pirruccello +95 more

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Nature Genetics(2021)10.1038/s41588-021-00935-7

N/A

4.0DataRank · unranked

191 citations

Masahiro Kanai, Wanson Choi, Xinyi Li, Saori Sakaue, Kenichi Yamamoto +95 more

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Nature Communications(2018)10.1038/s41467-018-04668-w

N/A

3.7DataRank · unranked

109 citations

Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan M. Bloom, Timothy Poterba +442 more

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1902766117

N/A

3.0DataRank · unranked

112 citations

Douglas P. Loesch, James A. Perry, Nancy L. Heard‐Costa, Daniel Taliun, Brian E. Cade +93 more

Hiatal hernia prevalence and natural history on non-contrast CT in the Multi-Ethnic Study of Atherosclerosis (MESA)

BMJ Open Gastroenterology(2021)10.1136/bmjgast-2020-000565

N/A

2.6DataRank · unranked

92 citations

Grant Hiura, Elizabeth C. Oelsner, Xiaorui Yin, R. Graham Barr, Benjamin M. Smith +2 more

Genome sequencing unveils a regulatory landscape of platelet reactivity

Nature Communications(2021)10.1038/s41467-021-23470-9

N/A

1.5DataRank · unranked

54 citations

Ming‐Huei Chen, Benjamin A.T. Rodriguez, Lisa R. Yanek, Arunoday Bhan, Brady Gaynor +94 more

Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort

JCI Insight(2020)10.1172/jci.insight.133984

N/A

1.5DataRank · unranked

43 citations

Michelle C. Rice, Katherine L. Hoffman, Clara Oromendia, Igor Barjaktarević, J. Michael Wells +22 more

Significance of FEV3/FEV6 in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD

CHEST Journal(2021)10.1016/j.chest.2021.10.046

N/A

1.4DataRank · unranked

36 citations

Daniela Markovic, Russell G. Buhr, Spyridon Fortis, Mehrdad Arjomandi, David Couper +17 more

Pulmonary Arterial Pruning and Longitudinal Change in Percent Emphysema and Lung Function

CHEST Journal(2021)10.1016/j.chest.2021.01.084

N/A

1.2DataRank · unranked

51 citations

Pietro Nardelli, Samuel Y. Ash, C.E. Come, Alejandro A. Díaz, Farbod N. Rahaghi +78 more

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

Nature Genetics(2022)10.1038/s41588-022-01225-6

N/A

1.2DataRank · unranked

63 citations

Corbin Quick, Hufeng Zhou, Sheila M. Gaynor, Yaowu Liu, Han Chen +95 more

A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities

American Journal of Respiratory and Critical Care Medicine(2023)10.1164/rccm.202212-2257oc

N/A

1.2DataRank · unranked

62 citations

Anna L. Peljto, John S. Kim, Hanfei Xu, Catherine L. Debban, Xianfeng Chen +33 more

Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Nature Communications(2022)10.1038/s41467-022-32275-3

N/A

1.1DataRank · unranked

63 citations

Daniel H. Katz, Julián Ávila-Pacheco, Alexander G. Bick, Akhil Pampana, Jeremy Robbins +95 more

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

New England Journal of Medicine(2020)10.1056/nejmoa2012410

N/A

1.1DataRank · unranked

1738 citations

Yifei Sun, Jonathan Platt, Jason Zucker, Matthew R. Baldwin, George Hripcsak +7 more

Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design

American Journal of Epidemiology(2022)10.1093/aje/kwac032

Top 19%

1.1DataRank

Top 19%36 citations

Akshaya Krishnaswamy, Pallavi Balte, Norrina B. Allen, Tauqeer Ali, Pramod Anugu +81 more

Randomization to Omega-3 Fatty Acid Supplementation and Endothelial Function in COPD: The COD-Fish Randomized Controlled Trial

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2020)10.15326/jcopdf.8.1.2020.0132

N/A

1.0DataRank · unranked

22 citations

Michael A. Thomashow, Natalie Yip, Kristin M. Burkart, Christian M. Lo Cascio, Daichi Shimbo +2 more

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

Genome Medicine(2021)10.1186/s13073-021-00917-8

Top 21%

0.976DataRank

Top 21%35 citations

Jiwon Lee, Tamar Sofer, Heming Wang, Man Zhang, Han Chen +94 more

Diffusing Capacity and Mortality in Chronic Obstructive Pulmonary Disease

Annals of the American Thoracic Society(2022)10.1513/annalsats.202203-226oc

N/A

0.873DataRank · unranked

28 citations

Nirupama Putcha, Neil R. MacIntyre, Robert L. Jensen, Gregory L. Kinney, William W. Stringer +12 more

Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity

SLEEP(2022)10.1093/sleep/zsac107

N/A

0.843DataRank · unranked

27 citations

Russell G. Buhr, P. Miguel Quibrera, Igor Barjaktarević, R. Graham Barr, Russell P. Bowler +18 more

Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

Nature Communications(2021)10.1038/s41467-021-23655-2

N/A

0.840DataRank · unranked

21 citations

Xiuwen Zheng, Cecelia Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos +91 more

Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts

The Lancet Respiratory Medicine(2020)10.1016/s2213-2600(20)30101-6

N/A

0.727DataRank · unranked

126 citations

Phuwanat Sakornsakolpat, Nick Shrine, Brian D. Hobbs, Dawn L. DeMeo, Catherine John +82 more

Ratio of FEV1/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function

CHEST Journal(2021)10.1016/j.chest.2021.01.067

N/A

0.675DataRank · unranked

18 citations

Alejandro P. Comellas, Surya P. Bhatt, Eric A. Hoffman, MeiLan K. Han, Nirav R. Bhakta +27 more

The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers

CHEST Journal(2021)10.1016/j.chest.2021.04.066

N/A

0.673DataRank · unranked

22 citations

Aman Gupta, Gregory L. Kinney, Carl R. Fuhrman, Joseph K. Leader, Alejandro A. Díaz +79 more

E-Cigarettes and Cardiopulmonary Health

Function(2021)10.1093/function/zqab004

N/A

0.646DataRank · unranked

73 citations

R. Graham Barr, Neal L. Benowitz, Aruni Bhatnagar, Hong Wei Chu, Pamela Dalton +22 more

Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing

Nature Genetics(2023)10.1038/s41588-022-01282-x

N/A

0.606DataRank · unranked

56 citations

Xingyan Wang, Seon-Kyeong Jang, Bryan C. Quach, J. Dylan Weissenkampen, Chachrit Khunsriraksakul +85 more

Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort

CHEST Journal(2022)10.1016/j.chest.2022.10.029

N/A

0.581DataRank · unranked

14 citations

P. Miguel Quibrera, David Couper, Donald P Tashkin, Eugene R. Bleecker, Claire M. Doerschuk +18 more

Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans

Thorax(2023)10.1136/thorax-2022-219158

N/A

0.561DataRank · unranked

41 citations

Jie Yang, Pallavi Balte, Eric A. Hoffman, Ani Manichaikul, Yifei Sun +36 more

Investigating Associations of Omega-3 Fatty Acids, Lung Function Decline, and Airway Obstruction

American Journal of Respiratory and Critical Care Medicine(2023)10.1164/rccm.202301-0074oc

N/A

0.561DataRank · unranked

41 citations

Pallavi Balte, Traci M. Bartz, R. Graham Barr, Myriam Fornage, Mariaelisa Graff +19 more

Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

International Journal of COPD(2021)10.2147/copd.s301466

Top 35%

0.557DataRank

Top 35%15 citations

Frank Li, Jiwoong Choi, Babak Haghighi, Sanghun Choi, Prathish K. Rajaraman +21 more

Systemic Markers of Lung Function and Forced Expiratory Volume in 1 Second Decline across Diverse Cohorts

Annals of the American Thoracic Society(2023)10.1513/annalsats.202210-857oc

N/A

0.556DataRank · unranked

13 citations

Katherine Pratte, Claudia Flexeder, Hans Petersen, Hong Dang, Yanlin Ma +49 more

Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis

American Journal of Respiratory and Critical Care Medicine(2022)10.1164/rccm.202108-1907oc

N/A

0.546DataRank · unranked

37 citations

Tianxiao Huan, Daniel L. McCartney, Geetha Chittoor, Maaike de Vries, Lies Lahousse +57 more

Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR

American Journal of Respiratory and Critical Care Medicine(2023)10.1164/rccm.202302-0207oc

N/A

0.483DataRank · unranked

24 citations

Han sang woo, Kirsten Koehler, Amanda J. Gassett, Laura M. Paulin, Neil E. Alexis +17 more

A Research Agenda to Improve Outcomes in Patients with Chronic Obstructive Pulmonary Disease and Cardiovascular Disease: An Official American Thoracic Society Research Statement

American Journal of Respiratory and Critical Care Medicine(2024)10.1164/rccm.202407-1320st

N/A

0.457DataRank · unranked

20 citations

Jennifer K Quint, Nathaniel M. Hawkins, Nirupama Putcha, Alan Hamilton, Peter K. Lindenauer +17 more

Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data

Human Molecular Genetics(2022)10.1093/hmg/ddac117

N/A

0.455DataRank · unranked

6 citations

Julian Hecker, R. Graham Barr, Eric Boerwinkle, Brian E. Cade, Adolfo Correa +21 more

Associations of ω-3 Fatty Acids With Interstitial Lung Disease and Lung Imaging Abnormalities Among Adults

American Journal of Epidemiology(2020)10.1093/aje/kwaa168

N/A

0.449DataRank · unranked

19 citations

Brian T. Steffen, Anna J. Podolanczuk, Steven M. Kawut, Imre Noth, Ganesh Raghu +17 more

Novel Subtypes of Pulmonary Emphysema Based on Spatially-Informed Lung Texture Learning: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study

IEEE Transactions on Medical Imaging(2021)10.1109/tmi.2021.3094660

N/A

0.442DataRank · unranked

18 citations

Elsa D. Angelini, Pallavi Balte, Eric A. Hoffman, John H. M. Austin, Benjamin M. Smith +3 more

Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD

CHEST Journal(2022)10.1016/j.chest.2022.11.009

N/A

0.425DataRank · unranked

16 citations

P. Miguel Quibrera, Alejandro P. Comellas, Surya P. Bhatt, Donald P Tashkin, Eric A. Hoffman +52 more

Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS

Respiratory Research(2022)10.1186/s12931-022-02225-0

N/A

0.416DataRank · unranked

15 citations

Han Woo, Chen Liu, Anna Tillery sup sup, Amanda J. Gassett, Richard E. Kanner +22 more

The Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study

American Journal of Respiratory and Critical Care Medicine(2024)10.1164/rccm.202310-1965oc

N/A

0.403DataRank · unranked

10 citations

Daniela Markovic, Han Woo, Mehrdad Arjomandi, R. Graham Barr, Russell P. Bowler +22 more

A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies

Nature Computational Science(2025)10.1038/s43588-024-00764-8

N/A

0.393DataRank · unranked

10 citations

Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Yuxuan Wang +95 more

Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design

medRxiv(2021)10.1101/2021.03.19.21253986

Top 48%

0.380DataRank

Top 48%5 citations

Norrina B. Allen, Tauqeer Ali, Pramod Anugu, Howard Andrews, Alyssa Asaro +77 more

Air Pollution Exposure and Interstitial Lung Features in SPIROMICS Participants with Chronic Obstructive Pulmonary Disease

Annals of the American Thoracic Society(2024)10.1513/annalsats.202308-741oc

N/A

0.374DataRank · unranked

6 citations

Laura M. Paulin, Amanda J. Gassett, Han Woo, Eric A. Hoffman, John D. Newell +14 more

Association of Lung Quantitative CT Scan Textures With Systemic Inflammation and Mortality in COPD

CHEST Journal(2025)10.1016/j.chest.2025.04.017

N/A

0.368DataRank · unranked

9 citations

Muhammad F. A. Chaudhary, Anthony D. El-Sokkary, Eric A. Hoffman, Alejandro P. Comellas, Junfeng Guo +19 more

Changes in Lung Volumes with Spirometric Disease Progression in COPD

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2023)10.15326/jcopdf.2022.0363

N/A

0.345DataRank · unranked

9 citations

Siyang Zeng, Jianhong Chen, Surya P. Bhatt, Fereidoun Abtin, Igor Barjaktarević +27 more

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Nature Communications(2020)10.1038/s41467-020-15236-6

Top 57%

0.275DataRank

Top 57%2 citations

Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan M. Bloom, Timothy Poterba +442 more

Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Nature Genetics(2021)10.1038/s41588-021-00979-9

N/A

0.246DataRank · unranked

4 citations

Masahiro Kanai, Wanson Choi, Xinyi Li, Saori Sakaue, Kenichi Yamamoto +95 more

Association of Occupational Exposures and Chronic Obstructive Pulmonary Disease Morbidity

Journal of Occupational and Environmental Medicine(2023)10.1097/jom.0000000000002850

N/A

0.241DataRank · unranked

4 citations

Peter S. J. Lees, Kirsten Koehler, Jessie P. Buckley, Lesliam Quirós-Alcalá, MeiLan K. Han +15 more

Investigating associations of omega-3 fatty acids, lung function decline, and airway obstruction

medRxiv(2023)10.1101/2023.01.18.23284671

N/A

0.208DataRank · unranked

3 citations

Palavi Balte, Traci M. Bartz, R. Graham Barr, Myriam Fornage, Mariaelisa Graff +19 more

Platelet activation and COPD-related clinical and imaging characteristics: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study

Respiratory Medicine(2025)10.1016/j.rmed.2025.108058

N/A

0.208DataRank · unranked

3 citations

Eric A. Hoffman, Martin R. Prince, Emlyn Hughes, Stephen Dashnaw, Christian M. Lo Cascio +9 more

Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function

UNC Libraries(2020)10.17615/6mem-qn63

N/A

0.208DataRank · unranked

3 citations

Matthew Kowgier, Tamara B. Harris, Wei Gao, Xiangjun Gu, Rasika A. Mathias +27 more

Peripheral Blood Mononuclear Cell Gene Expression Associated with Pulmonary Microvascular Perfusion: The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease

Annals of the American Thoracic Society(2024)10.1513/annalsats.202305-417oc

N/A

0.183DataRank · unranked

2 citations

Tess D. Pottinger, Jens Vogel‐Claussen, Charles A. Powell, François Aguet, Norrina B. Allen +21 more

Associations of Prepandemic Lung Function and Structure with COVID-19 Outcomes: The C4R Study

American Journal of Respiratory and Critical Care Medicine(2025)10.1164/rccm.202408-1656oc

N/A

0.165DataRank · unranked

2 citations

John S. Kim, Yifei Sun, Nori Allen, Elsa D. Angelini, Alexander Arynchyn +48 more

Proteomic discovery analysis of quantitatively assessed emphysema in the general population. The MESA Lung Study

Respiratory Research(2025)10.1186/s12931-025-03312-8

N/A

0.165DataRank · unranked

2 citations

L. Ruvuna, Claire Guo, Yifei Sun, Katherine Pratte, Ani Manichaikul +25 more

Soluble Receptor for Advanced Glycation End Products (sRAGE) as a Biomarker of COPD

(2020)10.21203/rs.3.rs-135754/v1

N/A

0.133DataRank · unranked

1 citations

Jeffrey L. Curtis, Katerina Kechris, David Couper, Michael H. Cho, Edwin K. Silverman +30 more

Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function

American Journal of Clinical Nutrition(2024)10.1016/j.ajcnut.2024.03.007

N/A

0.104DataRank · unranked

1 citations

Nathan Gaddis, Bonnie Patchen, Jiayi Xu, R. Graham Barr, George O'connor +7 more

Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

Research Square (Research Square)(2020)10.21203/rs.3.rs-31250/v1

Top 78%

0.104DataRank

Top 78%1 citations

Frank Li, Jiwoong Choi, Babak Haghighi, Sanghun Choi, Prathish K. Rajaraman +21 more

Proteomics and machine learning in the prediction and explanation of low pectoralis muscle area

Scientific Reports(2024)10.1038/s41598-024-68447-y

N/A

0.104DataRank · unranked

1 citations

J.W. Chiles, Stefanie Mason, Toru Shirahata, Víctor M. Castro, Elizabeth Regan +90 more

Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants

Genome Biology(2026)10.1186/s13059-025-03921-y

Top 78%

0.104DataRank

Top 78%1 citations

Xiaowei Hu, Kangjin Kim, Sung Chun, Peter Orchard, Dandi Qiao +65 more

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Nature Genetics(2023)10.1038/s41588-023-01314-0

N/A

0DataRank · unranked

190 citations

Abril G. Izquierdo, Jing Chen, Richard Packer, Robert J. Hall, Anna L. Guyatt +95 more

cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

Nature Methods(2025)10.1038/s41592-025-02919-5

N/A

0DataRank · unranked

0 citations

Yi Zhang, Xihao Li, Margaret Sunitha Selvaraj, Zilin Li, Hufeng Zhou +544 more

Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study

The Lancet Digital Health(2023)10.1016/s2589-7500(22)00232-1

N/A

0DataRank · unranked

43 citations

Eric A. Hoffman, Junfeng Guo, Alejandro P Comellas, John D. Newell, Prashant Nagpal +22 more

Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease

American Journal of Respiratory and Critical Care Medicine(2023)10.1164/rccm.202209-1698pp

N/A

0DataRank · unranked

33 citations

R. Graham Barr, MeiLan K. Han, Wayne H. Anderson, Igor Barjaktarević, Eugene R. Bleecker +14 more

Impact of Bronchiectasis on COPD Severity and Alpha-1 Antitrypsin Deficiency as a Risk Factor in Individuals with a Heavy Smoking History

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2023)10.15326/jcopdf.2022.0388

N/A

0DataRank · unranked

2 citations

Chad R. Marion, Frank Genese, John D. Newell, Wanda K. O’Neal, Xingnan Li +21 more

Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis

Respiratory Research(2023)10.1186/s12931-023-02316-6

N/A

0DataRank · unranked

8 citations

Craig Riley, Aabida Saferali, Peter J. Castaldi, Grace Zhang, François Aguet +17 more

Ambient Air Pollution Exposure and Sleep Quality in COPD

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2023)10.15326/jcopdf.2022.0350

N/A

0DataRank · unranked

6 citations

Abigail L. Koch, Nirupama Putcha, Han Woo, Amanda J. Gassett, Laura M. Paulin +20 more

CT-derived pectoralis composition and incident pneumonia hospitalization using fully automated deep-learning algorithm: multi-ethnic study of atherosclerosis

European Radiology(2023)10.1007/s00330-023-10372-1

N/A

0DataRank · unranked

3 citations

Quincy A. Hathaway, David A. Bluemke, Arta Kasaeian, Joshua G. Klein, Matthew J. Budoff +6 more

Lung Structure and Risk of Sleep Apnea in SPIROMICS

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2023)10.15326/jcopdf.2023.0411

N/A

0DataRank · unranked

3 citations

Tracie L. Shing, Andrew M. Namen, David Couper, Benjamin M. Smith, R. Graham Barr +21 more

Impact of Bronchiectasis on COPD Severity and Alpha-1 Antitrypsin Deficiency as a Risk Factor in Individuals with a Heavy Smoking History

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2023)10.15326/jcopdf.2023.0388

N/A

0DataRank · unranked

2 citations

Chad R. Marion, Frank Genese, John D. Newell, Wanda K. O’Neal, Xingnan Li +21 more

Multi-View Cnn For Total Lung Volume Inference On Cardiac Computed Tomography

PubMed(2023)10.1109/isbi53787.2023.10230821

N/A

0DataRank · unranked

3 citations

Elsa D. Angelini, Yifei Sun, Benjamin M. Smith, Eric A. Hoffman, Karen Hinckley Stukovsky +7 more

Returning incidentally discovered Hepatitis C RNA-seq results to COPDGene study participants

npj Genomic Medicine(2023)10.1038/s41525-023-00379-4

N/A

0DataRank · unranked

0 citations

Arthur Y. Kim, Barry J. Make, Elizabeth A. Regan, Jarrett D. Morrow, Craig P. Hersh +23 more

Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD

UNC Libraries(2023)10.17615/t4sz-0y09

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0 citations

R.P. Bowler, S.P. Peters, P. Miguel Quibrera, F.J. Martinez, N.N. Hansel +24 more

Association of Ground-Glass Opacities with Systemic Inflammation and Progression of Emphysema

American Journal of Respiratory and Critical Care Medicine(2024)10.1164/rccm.202310-1825oc

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8 citations

Junfeng Guo, Prashant Nagpal, Muhammad F. A. Chaudhary, John D. Newell, Sarah E. Gerard +21 more

Estimating ambient air pollutant concentrations outside and inside homes in the Subpopulations and Intermediate outcomes in COPD air pollution (SPIROMICS air) cohort

Environmental Research(2024)10.1016/j.envres.2024.119512

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3 citations

Amanda J. Gassett, Coralynn Sack, Laura M. Paulin, C.S. Pirozzi, R. Graham Barr +8 more

Dynamic and prognostic proteomic associations with FEV 1 decline in chronic obstructive pulmonary disease

medRxiv(2024)10.1101/2024.08.07.24311507

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2 citations

Kahkeshan Hijazi, Daniel E. Guzman, Claire Guo, Joseph Loureiro, Edward Khokhlovich +34 more

Unsupervised Airway Tree Clustering with Deep Learning: the Multi-Ethnic Study of Atherosclerosis (Mesa) Lung Study

PubMed(2024)10.1109/isbi56570.2024.10635651

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1 citations

Elsa D. Angelini, R. Graham Barr, Norrina B. Allen, Alain G. Bertoni, Eric A. Hoffman +8 more

Robust deep labeling of radiological emphysema subtypes using squeeze and excitation convolutional neural networks: The MESA Lung and SPIROMICS Studies

arXiv (Cornell University)(2024)10.48550/arxiv.2403.00257

N/A

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0 citations

Nabil Ettehadi, Soroush Arabshahi, Yifei Sun, Karen Hinkley Stukovsky, Karol E. Watson +8 more

Indices of Childhood Socioeconomic Status and Dysanapsis among Older Adults: The Multi-Ethnic Study of Atherosclerosis Lung Study

Annals of the American Thoracic Society(2024)10.1513/annalsats.202401-006rl

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0 citations

Jana A. Hirsh, Eric A. Hoffman, Norrina B. Allen, Alain G. Bertoni, Junfeng Guo +11 more

Meta-analysis of exome array data identifies six novel genetic loci for lung function

UNC Libraries(2024)10.17615/2hwq-jx43

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0 citations

André G. Uitterlinden, George O'connor, Jonathan Marten, Charlotta Pisinger, K. Strauch +95 more

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Digital Commons@Becker (Washington University School of Medicine)(2024)10.17615/m0db-s715

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0 citations

Patricia A. Cassano, E.G. Holliday, Tianxiao Huan, Richard H. Myers, Woo Jin Kim +95 more

Association of Forced Vital Capacity with the Developmental Gene NCOR2

Tampere University Institutional Repository (Tampere University)(2024)10.17615/agfx-qc43

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0 citations

Lies Lahousse, Henry Völzke, K. De Jong, Thor Aspelund, G. Eiríksdóttir +95 more

Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design

UNC Libraries(2024)10.17615/sz7d-v414

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Yuan‐I Min, Gregory L. Kinney, Mary Cushman, R. Graham Barr, Wendy S. Post +80 more

Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study

UNC Libraries(2024)10.17615/04sy-k027

N/A

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0 citations

DAVID R. JACOBS, Wendy White, David Couper, Joseph E. Schwartz, George O'connor +20 more

Harmonization of Respiratory Data from 9 US Population-Based Cohorts

UNC Libraries(2024)10.17615/a0zy-yy16

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Stephanie J. London, Yunlong Zhang, R. Graham Barr, Richard F. Kaplan, P. Balte +21 more

International Contrast Ultrasound Society Safety Round Table

Journal of Ultrasound in Medicine(2025)10.1002/jum.70084

N/A

0DataRank · unranked

1 citations

Jordan B. Strom, Dirk‐André Clevert, Stephanie R. Wilson, Thomas R. Porter, Kassa Darge +1 more

Antinuclear antibodies and progression of quantitative interstitial lung changes: The Multi-Ethnic Study of Atherosclerosis (MESA)-Lung Study

Respiratory Medicine(2025)10.1016/j.rmed.2025.107955

N/A

0DataRank · unranked

0 citations

Michael George, John S. Kim, Jesse Y. Hsu, Anna J. Podolanczuk, Eric A. Hoffman +9 more

Phase-Resolved Functional Lung MRI Evaluation of Dynamic Hyperinflation Induced by Metronome-Paced Tachypnea in Patients with Chronic Obstructive Pulmonary Disease

COPD Journal of Chronic Obstructive Pulmonary Disease(2025)10.1080/15412555.2025.2502671

N/A

0DataRank · unranked

0 citations

Filip Klimeš, Andreas Voskrebenzev, Lea Behrendt, Till F. Kaireit, Marius Wernz +9 more

Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans

UNC Libraries(2025)10.17615/6455-md85

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0 citations

Fernando J. Martínez, David Couper, Mark T. Dransfield, Martin R. Prince, Elsa D. Angelini +36 more

Vessel and Airway Characteristics in One-Year Computed Tomography-defined Rapid Emphysema Progression: SPIROMICS.

UNC Libraries(2025)10.17615/esdr-g636

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0DataRank · unranked

0 citations

Stephen Rennard, MeiLan K. Han, Sarah E. Gerard, Amin Motahari, Richard E. Kanner +20 more

Marginal structural models for quantifying the causal effects of exposure to ambient air pollution on progression of CT emphysema in the MESA lung and MESA air studies

American Journal of Epidemiology(2025)10.1093/aje/kwaf252

N/A

0DataRank · unranked

0 citations

Meng Wang, Rachel S. Heise, Carrie L. Pistenmaa, Eric A. Hoffman, Lianne Sheppard +7 more

Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology

UNC Libraries(2020)10.17615/33pe-2827

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0 citations

R.E. Kanner, J. Choi, E. Bleecker, F.J. Martinez, W. O apos Neal +15 more

Antiphospholipid antibodies and subclinical interstitial lung disease in the MESA cohort

Respiratory Research(2025)10.1186/s12931-025-03395-3

N/A

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0 citations

Mary Salvatore, John D. Newell, Jubal R. Watts, P. H. Nath, Sushilkumar K. Sonavane +8 more

APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema

UNC Libraries(2020)10.17615/t31a-f298

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0DataRank · unranked

0 citations

Karol E. Watson, Martin D. Tobin, Michael Y. Tsai, Firas S. Ahmed, Marcy F. Petrini +26 more

Lung function decline over 25 years of follow-up among black and white adults in the ARIC study cohort

UNC Libraries(2020)10.17615/e6ge-rb19

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0 citations

Sunil Agarwal, R. Graham Barr, Stephanie J. London, Noorie Hyun, David Couper +5 more

Anemia and adverse outcomes in a chronic obstructive pulmonary disease population with a high burden of comorbidities an analysis from SPIROMICS

UNC Libraries(2020)10.17615/8j8c-8w77

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0 citations

G.G. Paul, J. Michael Wells, R.A. Wise, J. Woo, W.K. O apos Neal +15 more

Replication and fine mapping of asthma-associated loci in individuals of African ancestry

UNC Libraries(2020)10.17615/fpe5-k921

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0 citations

Meng, Yan, Alkes L. Price, R. Graham Barr, Laura R. Loehr, Wendy White +16 more

Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort

npj Biofilms and Microbiomes(2021)10.1038/s41522-021-00185-9

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70 citations

Lesa Begley, John R. Erb‐Downward, Christine M. Freeman, Siddharth Madapoosi, Neil E. Alexis +27 more

Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos

UNC Libraries(2020)10.17615/t83e-sv82

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0 citations

B. S. Weir, Sylvia Wassertheil‐Smoller, Anne E. Justice, Mariaelisa Graff, Martha L. Daviglus +32 more

Classifying Chronic Lower Respiratory Disease Events in Epidemiologic Cohort Studies

UNC Libraries(2020)10.17615/s144-n304

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0 citations

Laura R. Loehr, Ashley G. Henderson, R. Graham Barr, Benjamin M. Smith, Andrew L. Ries +7 more

SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs

UNC Libraries(2020)10.17615/chh1-4c06

N/A

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0 citations

Nadia N. Hansel, Junfeng Guo, Stephen I. Rennard, Jonathan Goldin, Fernando J. Martínez +12 more

Radiological Society of North America/Quantitative Imaging Biomarker Alliance Shear Wave Speed Bias Quantification in Elastic and Viscoelastic Phantoms

Journal of Ultrasound in Medicine(2021)10.1002/jum.15609

N/A

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50 citations

Andy Milkowski, R. Graham Barr, Paul L. Carson, Mathieu Couade, Jun Chen +39 more

Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD

CHEST Journal(2021)10.1016/j.chest.2021.10.049

N/A

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41 citations

Wanda K. O’Neal, Wayne H. Anderson, Mehmet Kesımer, Agathe Ceppe, Claire M. Doerschuk +52 more

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium

Genome Medicine(2021)10.1186/s13073-021-00866-2

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38 citations

Silva Kasela, Victor E. Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen +39 more

Erratum: Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers

Korean Journal of Radiology(2020)10.3348/kjr.2019.0912

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0 citations

Kum Ju Chae, Gong Yong Jin, Jiwoong Choi, Ching‐Long Lin, Eric A. Hoffman +18 more

Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults

CHEST Journal(2021)10.1016/j.chest.2021.03.058

N/A

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30 citations

John S. Kim, Matthew Allison, Jon T. Giles, Eric A. Hoffman, Jingzhong Ding +3 more

CT-Assessed Dysanapsis and Airflow Obstruction in Early and Mid Adulthood

CHEST Journal(2021)10.1016/j.chest.2021.08.038

N/A

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27 citations

Grant Hiura, R. Graham Barr, Jessica C. Sieren, Benjamin M. Smith, Eric A. Hoffman +1 more

Latent traits of lung tissue patterns in former smokers derived by dual channel deep learning in computed tomography images

Scientific Reports(2021)10.1038/s41598-021-84547-5

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17 citations

Jiwoong Choi, Chunrui Zou, John D. Newell, Alejandro P. Comellas, Chang Hyun Lee +20 more

Aortic enlargement in chronic obstructive pulmonary disease (COPD) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD study

International Journal of Cardiology(2021)10.1016/j.ijcard.2021.02.017

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16 citations

Alessandra Albini, R. Graham Barr, Megha A. Parikh, Julia P. Kern, Eric A. Hoffman +8 more

Quantitative CT‐Based Methods for Bone Microstructural Measures and Their Relationships With Vertebral Fractures in a Pilot Study on Smokers

JBMR Plus(2021)10.1002/jbm4.10484

N/A

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12 citations

Alejandro P Comellas, Elizabeth A. Regan, Indranil Guha, Amal Shibli‐Rahhal, Mishaela R. Rubin +6 more

Reply to “the impact of mechanical properties on aortic dilation in patients with COPD and emphysema”

International Journal of Cardiology(2021)10.1016/j.ijcard.2021.04.045

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0 citations

Grant Hiura, R. Graham Barr, Martin R. Prince, Kana Fujikura

Air Pollution Exposure and Interstitial Lung Abnormalities in COPD: Analysis of the SPIROMICS Cohort

(2021)10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3161

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0 citations

Laura M. Paulin, Amanda J. Gassett, Han Woo, Eric A. Hoffman, P. Woodruff +10 more

Air Pollutant Exposure-by-Gene Interactions Associated with Emphysema, Lung Structure, and Lung Function in SPIROMICS

(2021)10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1095

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0 citations

Laura M. Paulin, Joel D. Kaufman, E. Ampleford, Han Woo, G.A. Hawkins +26 more

Intakes of long-chain n–3 polyunsaturated fatty acids and fish in relation to measurements of subclinical atherosclerosis

UNC Libraries(2020)10.17615/3e23-ek25

N/A

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7 citations

David S. Siscovick, Nancy S. Jenny, R. Graham Barr, Rui Jiang, Colin O. Wu +8 more

Antinuclear antibodies and subclinical interstitial lung disease in community-dwelling adults: the MESA study

European Respiratory Journal(2020)10.1183/13993003.02262-2019

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4 citations

John H. M. Austin, Steven M. Kawut, Ganesh Raghu, Eric A. Hoffman, John D. Newell +6 more

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

Nature Methods(2022)10.1038/s41592-022-01640-x

N/A

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109 citations

Xihao Li, Hufeng Zhou, Sheila M. Gaynor, Margaret Sunitha Selvaraj, Theodore Arapoglou +95 more

Clinical Phenotypes of Atopy and Asthma in COPD

CHEST Journal(2020)10.1016/j.chest.2020.04.069

N/A

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28 citations

Ashraf Fawzy, Elizabeth C. Matsui, Mark C. Liu, R.P. Bowler, Prescott G. Woodruff +23 more

Regional distribution of high-attenuation areas on chest computed tomography in the Multi-Ethnic Study of Atherosclerosis

ERJ Open Research(2020)10.1183/23120541.00115-2019

N/A

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14 citations

Steven M. Kawut, Ganesh Raghu, Eric A. Hoffman, Russell P. Tracy, Purnema Madahar +5 more

Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD

CHEST Journal(2020)10.1016/j.chest.2019.11.047

N/A

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53 citations

Agathe Ceppe, Claire M. Doerschuk, David Couper, Eric A. Hoffman, Alejandro P. Comellas +53 more

Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation(2022)10.15326/jcopdf.2021.0241

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35 citations

David Couper, Igor Barjaktarević, Christopher B. Cooper, Richard E. Kanner, C.S. Pirozzi +21 more

The Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease

International Journal of COPD(2020)10.2147/copd.s238933

N/A

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61 citations

Han Woo, Laura M. Paulin, Amy Kind, Nirupama Putcha, Amanda J. Gassett +14 more

Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR

The Science of The Total Environment(2022)10.1016/j.scitotenv.2022.154694

N/A

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14 citations

Han Woo, Nirupama Putcha, Laura M. Paulin, Kirsten Koehler, Ashraf Fawzy +20 more

Association of Pericardial Fat with Cardiac Structure, Function, and Mechanics: The Multi-Ethnic Study of Atherosclerosis

Journal of the American Society of Echocardiography(2022)10.1016/j.echo.2022.01.005

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11 citations

Mary Putt, Wei Yang, Alain G. Bertoni, Jingzhong Ding, João A.C. Lima +9 more

Robust Measures of Image-Registration-Derived Lung Biomechanics in SPIROMICS

Journal of Imaging(2022)10.3390/jimaging8110309

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5 citations

Di Wang, Muhammad F. A. Chaudhary, Wei Shao, Sarah E. Gerard, Oguz C. Durumeric +6 more

Five-year Progression of Emphysema and Air Trapping at CT in Smokers with and Those without Chronic Obstructive Pulmonary Disease: Results from the COPDGene Study

Radiology(2020)10.1148/radiol.2020191429

N/A

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100 citations

Matthew Strand, Eva M. van Rikxoort, Eric A. Hoffman, R. Graham Barr, Jean Paul Charbonnier +10 more

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