Douglas J. Kojetin

Also affiliated with Vanderbilt University, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

Biochemistry, Genetics and Molecular BiologyNeuroscienceComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages”.

Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

Immunity(2024)10.1016/j.immuni.2024.03.020

N/A

0.533DataRank · unranked

34 citations

Rosa A. Sierra-Mondragon, Rachel V. Jimenez, Darwin Chang, Eslam Mohamed, Shiun Chang +23 more

Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ

eLife(2024)10.7554/elife.99782

N/A

0.385DataRank · unranked

12 citations

Douglas J. Kojetin, Jinsai Shang

Structure–Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 (34) for Autoimmune Disorders

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01413

N/A

0.373DataRank · unranked

11 citations

Di Zhu, Kevin L. Greenman, Claudia Ruiz, Jinsai Shang, Qun Lu +7 more

The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors

British Journal of Pharmacology(2024)10.1111/bph.17366

N/A

0.373DataRank · unranked

11 citations

Beatrice Pflüger‐Müller, Virna Margarita Martín Giménez, Fiona Sailer, Henrik Dirks, Simonida Zehr +21 more

Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.23.590805

N/A

0.360DataRank · unranked

10 citations

Di Zhu, Jinsai Shang, Qianzhen Shao, Zhongyue J Yang, Theodore M. Kamenecka +2 more

Assessment of NR4A Ligands that Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.22.109017

N/A

0.269DataRank · unranked

5 citations

Hua Lin, Pasha M. Khan, Ian Mitchelle S. de Vera, Theodore M. Kamenecka, Douglas J. Kojetin +1 more

Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy

eLife(2025)10.7554/elife.106697

N/A

0.104DataRank · unranked

1 citations

Brian S. MacTavish, Zane T. Laughlin, Mithun Nag Karadi Giridhar, Jinsai Shang, Mei Li +5 more

Structural basis of interdomain communication in PPARγ

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.13.499031

N/A

0DataRank · unranked

6 citations

Paola Munoz‐Tello, Kuan‐Ting Kuo, Brian S. MacTavish, Xiaoyu Yu, Daniel Scholl +10 more

Molecular basis of ligand-dependent Nurr1-RXRα activation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.08.515219

N/A

0DataRank · unranked

0 citations

Jinsai Shang, Douglas J. Kojetin, Xiaoyu Yu

Molecular basis of ligand-dependent Nurr1-RXRα activation

eLife(2023)10.7554/elife.85039

N/A

0DataRank · unranked

18 citations

Jinsai Shang, Douglas J. Kojetin, Xiaoyu Yu

Go big and go home: A bulky extension makes promiscuous ligands settle down

Structure(2023)10.1016/j.str.2023.11.001

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0DataRank · unranked

0 citations

Douglas J. Kojetin, Xiaoyu Yu

Structural insights into IMP2 dimerization and RNA binding

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.16.580656

N/A

0DataRank · unranked

3 citations

Paola Munoz‐Tello, Timothy O’Leary, Xiaoyu Yu, Mithun Nag, Althea Hansel-Harris +6 more

Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.15.594037

N/A

0DataRank · unranked

0 citations

Douglas J. Kojetin, Jinsai Shang

Author response: Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ

(2024)10.7554/elife.99782.2.sa0

N/A

0DataRank · unranked

0 citations

Douglas J. Kojetin, Jinsai Shang

Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ

eLife(2024)10.7554/elife.99782.2

N/A

0DataRank · unranked

0 citations

Douglas J. Kojetin, Jinsai Shang

Structural Basis of PPARγ-Mediated Transcriptional Repression by the Covalent Inverse Agonist FX-909

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01252

N/A

0DataRank · unranked

4 citations

Liudmyla Arifova, Paola Munoz‐Tello, Xiaoyu Yu, Mithun Nag Karadi Giridhar, Jinhui Dong +5 more

Structural insights into IMP2 dimerization and RNA binding

Journal of Structural Biology(2025)10.1016/j.jsb.2025.108247

N/A

0DataRank · unranked

1 citations

Paola Munoz‐Tello, Timothy R. O’Leary, Xiaoyu Yu, Mithun Nag Karadi Giridhar, Alexander D. Hondros +7 more

Structural basis of PPARγ-mediated transcriptional repression by the covalent inverse agonist FX-909

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.04.651770

N/A

0DataRank · unranked

2 citations

Liudmyla Arifova, Paola Munoz‐Tello, Xiaoyu Yu, Mithun Nag Karadi Giridhar, Jinhui Dong +5 more

A molecular switch regulating transcriptional repression and activation of PPARγ

Nature Communications(2020)10.1038/s41467-020-14750-x

N/A

0DataRank · unranked

98 citations

Sarah A. Mosure, Jie Zheng, Richard Brust, Jared Bass, Ashley Nichols +4 more

A tethering mechanism underlies Pin1-catalyzed proline cis–trans isomerization at a noncanonical site

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2414606122

N/A

0DataRank · unranked

0 citations

Jonathan Chuck, Paola Munoz‐Tello, Douglas J. Kojetin, Christopher C. Williams

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00894

N/A

0DataRank · unranked

66 citations

Hua Lin, Pasha M. Khan, Ian Mitchelle S. de Vera, Theodore M. Kamenecka, Douglas J. Kojetin +1 more

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.05.079277

N/A

0DataRank · unranked

2 citations

Jinsai Shang, Paola Munoz‐Tello, Douglas J. Kojetin, Sarah A. Mosure

Structural Mechanism Underlying Ligand Binding and Activation of PPARγ

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.22.298109

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0DataRank · unranked

1 citations

Douglas J. Kojetin, Jinsai Shang

CAR directs T cell adaptation to bile acids in the small intestine

Nature(2021)10.1038/s41586-021-03421-6

N/A

0DataRank · unranked

86 citations

Xiangsheng Huang, Hongtao Wang, Courtney L Hegner, Yujin Liu, Jinsai Shang +15 more

Structural mechanism underlying ligand binding and activation of PPARγ

Structure(2021)10.1016/j.str.2021.02.006

N/A

0DataRank · unranked

47 citations

Douglas J. Kojetin, Jinsai Shang

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ

Science Advances(2021)10.1126/sciadv.abc6479

N/A

0DataRank · unranked

22 citations

Timothy S. Strutzenberg, Jinsai Shang, Paola Munoz‐Tello, Laura A. Solt, Patrick R. Griffin +2 more