Theodore R. Holman

Biochemistry, Genetics and Molecular BiologyMedicineNursingPharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “Supplementation with omega‐3 or omega‐6 fatty acids attenuates platelet reactivity in postmenopausal women”.

Supplementation with omega‐3 or omega‐6 fatty acids attenuates platelet reactivity in postmenopausal women

Clinical and Translational Science(2022)10.1111/cts.13366

N/A

0.485DataRank · unranked

13 citations

Livia Stanger, John C. Freedman, Amanda Prieur, Rachel Thav, Jennyfer Tena +3 more

A 12‐lipoxygenase‐Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish

The FASEB Journal(2020)10.1096/fj.201902308rr

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0DataRank · unranked

20 citations

Abhishek Kulkarni, Niharika Samala, Cody A. Sorrell, Kimberley El, Isra Haider +7 more

Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1

Biochemistry(2020)10.1021/acs.biochem.0c00622

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0DataRank · unranked

18 citations

Thomas Horn, Benjamin E. Tourdot, Adriana Yamaguchi, Chakrapani Kalyanaraman, William S. Conrad +5 more

Altered specificity of 15-LOX-1 in the biosynthesis of 7S,14S-diHDHA implicates 15-LOX-2 in biosynthesis of resolvin D5

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.25.008573

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0DataRank · unranked

1 citations

Chakrapani Kalyanaraman, Benjamin E. Tourdot, William S. Conrad, Oluwayomi Akinkugbe, John C. Freedman +4 more

Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116349

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0DataRank · unranked

28 citations

Nathaniel C. Gilbert, Amanda Ohler, Michelle Armstrong, Steve Perry, Chakrapani Kalyanaraman +14 more

Docking and mutagenesis studies lead to improved inhibitor development of ML355 for human platelet 12-lipoxygenase

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116347

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0DataRank · unranked

14 citations

Ansari M. Aleem, Jennyfer Tena, Mirella Rivera-Velazquez, Harman Brah, Sarvind Tripathi +6 more

Structural basis for altered positional specificity of 15-lipoxygenase-1 with 5S-HETE and 7S-HDHA and the implications for the biosynthesis of resolvin E4

Archives of Biochemistry and Biophysics(2022)10.1016/j.abb.2022.109317

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0DataRank · unranked

7 citations

Christopher van Hoorebeke, James T. Sorrentino, Leslie Bautista, Oluwayomi Akinkugbe, William S. Conrad +3 more

Biochemical and hydrogen-deuterium exchange studies of the single nucleotide polymorphism Y649C in human platelet 12-lipoxygenase linked to a bleeding disorder

Archives of Biochemistry and Biophysics(2022)10.1016/j.abb.2022.109472

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4 citations

Rachel L. Signorelli, Adriana Yamaguchi, Eefie Chen, Michael Holinstat, Anthony T. Iavarone +3 more

Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors

Blood(2023)10.1182/blood.2023020441

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0DataRank · unranked

22 citations

Katrina A. Black, Michelle Tran, Wessel A. C. Burger, Hariprasad Venugopal, Theodore R. Holman +4 more

Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2218896120

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0DataRank · unranked

27 citations

Karolina Mikulska‐Ruminska, Yulia Y. Tyurina, Diane K. Luci, Adam Yasgar, Svetlana N. Samovich +23 more

Fatty acids negatively regulate platelet function through formation of noncanonical 15‐lipoxygenase‐derived eicosanoids

Pharmacology Research & Perspectives(2023)10.1002/prp2.1056

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0DataRank · unranked

12 citations

Christopher van Hoorebeke, Benjamin E. Tourdot, Steve Perry, Grace Lee, Nicole Rhoads +8 more

Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.10.532002

N/A

0DataRank · unranked

2 citations

Katrina A. Black, Michelle Tran, Hariprasad Venugopal, Theodore R. Holman, Michael Holinstat +3 more

Investigating the catalytic efficiency of C22-Fatty acids with LOX human isozymes and the platelet response of the C22-oxylipin products

Archives of Biochemistry and Biophysics(2023)10.1016/j.abb.2023.109742

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0DataRank · unranked

0 citations

Livia Stanger, Srihari Narendra, Michael Holinstat, Theodore R. Holman, Michelle Tran

Strikingly High Activity of 15‐Lipoxygenase Towards Di‐Polyunsaturated Arachidonoyl/Adrenoyl‐Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death

Angewandte Chemie International Edition(2024)10.1002/anie.202314710

N/A

0DataRank · unranked

52 citations

Karolina Mikulska‐Ruminska, Haider H. Dar, Yulia Y. Tyurina, Vladimir A. Tyurin, Austin B. Souryavong +17 more

The EPA oxylipin, 12-HEPE, directly regulates human platelet activity

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100807

N/A

0DataRank · unranked

7 citations

Livia Stanger, Andrew Rickenberg, Anthony Nguyễn, Taekyu Lee, Theodore R. Holman +2 more

12-Hepe Regulates the Antiplatelet Effects of Epa, the ω-3 Fatty Acid

Blood(2024)10.1182/blood-2024-212421

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0DataRank · unranked

2 citations

Livia Stanger, Andrew Rickenberg, Theodore R. Holman, Michael Holinstat, Krista Goerger

15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5

Journal of Lipid Research(2020)10.1194/jlr.ra120000777

N/A

0DataRank · unranked

51 citations

Chakrapani Kalyanaraman, Benjamin E. Tourdot, William S. Conrad, Oluwayomi Akinkugbe, John C. Freedman +4 more

Strikingly High Activity of 15‐Lipoxygenase Towards Di‐Polyunsaturated Arachidonoyl/Adrenoyl‐Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death

Angewandte Chemie(2024)10.1002/ange.202314710

N/A

0DataRank · unranked

0 citations

Karolina Mikulska‐Ruminska, Haider H. Dar, Yulia Y. Tyurina, Vladimir A. Tyurin, Austin B. Souryavong +17 more